Gene description for HYAL1
Gene name	hyaluronoglucosaminidase 1
Gene symbol	HYAL1
Other names/aliases	HYAL-1 LUCA1 MPS9 NAT6
Species	Homo sapiens
Database cross references - HYAL1
ExoCarta	ExoCarta_3373
Vesiclepedia	VP_3373
Entrez Gene	3373
HGNC	5320
MIM	607071
UniProt	Q12794
HYAL1 identified in sEVs derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723

Gene ontology annotations for HYAL1

Molecular Function     virus receptor activity GO:0001618 IDA     hyalurononglucosaminidase activity GO:0004415 IDA     hyalurononglucosaminidase activity GO:0004415 IDA     hyalurononglucosaminidase activity GO:0004415 TAS     chondroitin hydrolase activity GO:0052757 IEA Biological Process     response to reactive oxygen species GO:0000302 IDA     carbohydrate metabolic process GO:0005975 IEA     glycosaminoglycan catabolic process GO:0006027 TAS     inflammatory response GO:0006954 IDA     response to virus GO:0009615 IDA     chondroitin sulfate catabolic process GO:0030207 IEA     hyaluronan metabolic process GO:0030212 IDA     hyaluronan catabolic process GO:0030214 IBA     hyaluronan catabolic process GO:0030214 IDA     hyaluronan catabolic process GO:0030214 TAS     positive regulation of cell growth GO:0030307 IMP     negative regulation of cell growth GO:0030308 IDA     cellular response to platelet-derived growth factor stimulus GO:0036120 IDA     cellular response to fibroblast growth factor stimulus GO:0044344 IDA     positive regulation of angiogenesis GO:0045766 IMP     positive regulation of cell adhesion GO:0045785 IMP     response to antibiotic GO:0046677 IDA     cartilage development GO:0051216 IEP     embryonic skeletal joint morphogenesis GO:0060272 IEA     cellular response to interleukin-1 GO:0071347 IDA     cellular response to tumor necrosis factor GO:0071356 IEP     cellular response to pH GO:0071467 IDA     cellular response to UV-B GO:0071493 IDA     positive regulation of hyaluranon cable assembly GO:1900106 IDA Subcellular Localization     extracellular space GO:0005615 IDA     lysosome GO:0005764 IDA     cytoplasmic vesicle GO:0031410 IBA     cytoplasmic vesicle GO:0031410 IDA     hyaluranon cable GO:0036117 IDA     lysosomal lumen GO:0043202 TAS     extracellular exosome GO:0070062 HDA