Experiment description of studies that identified ARVCF in sEVs

1 Experiment ID 20 MISEV standards ✔ EM Biophysical techniques ✔ HSP90|CD63|CD81|LAMP1 Enriched markers ✔ GOLGA2|cytochrome c Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 17956143     Organism Homo sapiens Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells. Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS" Journal name JPR Publication year 2007 Sample Colorectal cancer cells Sample name HT29 Isolation/purification methods Differential centrifugation Sucrose density gradient Diafiltration Flotation density 1.16 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] Western blotting

2 Experiment ID 211 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|EpCAM|TFRC Enriched markers ✔ cytochrome c|GOLGA2 Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23333927     Organism Homo sapiens Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes. Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K." Journal name J Proteomics Publication year 2013 Sample Ovarian cancer cells Sample name IGROV1 Isolation/purification methods Differential centrifugation Ultracentrifugation Sucrose density gradient Flotation density 1.09-1.15 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

3 Experiment ID 212 MISEV standards ✔ CEM Biophysical techniques ✔ TSG101|Alix|EpCAM|TFRC Enriched markers ✔ Cytochrome C|GOLGA2 Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23333927     Organism Homo sapiens Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes. Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K." Journal name J Proteomics Publication year 2013 Sample Ovarian cancer cells Sample name OVCAR-3 Isolation/purification methods Differential centrifugation Ultracentrifugation Sucrose density gradient Flotation density 1.09-1.15 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

Protein-protein interactions for ARVCF

Protein Interactor ExoCarta ID Identification method PubMed Species 1 HNRNPH1 3187 Affinity Capture-RNA Homo sapiens 2 ANLN 54443 Affinity Capture-MS Homo sapiens 3 SLIRP 81892 Affinity Capture-MS Homo sapiens 4 CYSTM1 84418 Affinity Capture-MS Homo sapiens 5 EFNA4   Affinity Capture-MS Homo sapiens 6 TACR1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 7 SDC1 6382 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 8 Cdh1 12550 Affinity Capture-MS Mus musculus 9 S1PR2 9294 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 10 ERBB2IP 55914 Reconstituted Complex Homo sapiens 11 CDH8   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 12 P4HA2 8974 Affinity Capture-MS Homo sapiens 13 CTNNB1 1499 Affinity Capture-MS Homo sapiens Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 14 S100A2 6273 Affinity Capture-MS Homo sapiens 15 CYP2S1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 16 NR3C1 2908 Proximity Label-MS Homo sapiens 17 CDH15 1013 Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens Two-hybrid Homo sapiens 18 C11orf52 91894 Proximity Label-MS Homo sapiens 19 CCDC85A   Affinity Capture-MS Homo sapiens 20 CERS2 29956 Affinity Capture-MS Homo sapiens 21 GJB7   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 22 PROZ 8858 Affinity Capture-MS Homo sapiens 23 TAX1BP3 30851 Affinity Capture-MS Homo sapiens 24 CDH1 999 Proximity Label-MS Homo sapiens 25 CDH5   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 26 NTRK1 4914 Affinity Capture-MS Homo sapiens 27 GPR45   Affinity Capture-MS Homo sapiens 28 SCML1   Affinity Capture-MS Homo sapiens 29 CDH2 1000 Affinity Capture-MS Homo sapiens 30 EPHA2 1969 Proximity Label-MS Homo sapiens 31 ANK3   Proximity Label-MS Homo sapiens 32 RHOB 388 Proximity Label-MS Homo sapiens 33 CPA5   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 34 KRAS 3845 Proximity Label-MS Homo sapiens 35 CTNNA3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 36 SEMA4C 54910 Affinity Capture-MS Homo sapiens 37 CAV1 857 Proximity Label-MS Homo sapiens 38 CTDSPL 10217 Proximity Label-MS Homo sapiens 39 LNX1   Two-hybrid Homo sapiens 40 CDH12   Affinity Capture-MS Homo sapiens 41 PROSER2 254427 Affinity Capture-MS Homo sapiens View the network

Pathways in which ARVCF is involved

No pathways found