Gene description for NDUFB10
Gene name NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa
Gene symbol NDUFB10
Other names/aliases PDSW
Species Homo sapiens
 Database cross references - NDUFB10
ExoCarta ExoCarta_4716
Vesiclepedia VP_4716
Entrez Gene 4716
HGNC 7696
MIM 603843
UniProt O96000  
 NDUFB10 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
 Gene ontology annotations for NDUFB10
Molecular Function
    protein binding GO:0005515 IPI
    NADH dehydrogenase (ubiquinone) activity GO:0008137 NAS
Biological Process
    mitochondrial electron transport, NADH to ubiquinone GO:0006120 NAS
    aerobic respiration GO:0009060 NAS
    mitochondrial respiratory chain complex I assembly GO:0032981 IMP
    proton motive force-driven mitochondrial ATP synthesis GO:0042776 NAS
    proton transmembrane transport GO:1902600 IEA
Subcellular Localization
    mitochondrion GO:0005739 HTP
    mitochondrial inner membrane GO:0005743 IDA
    mitochondrial inner membrane GO:0005743 IMP
    mitochondrial inner membrane GO:0005743 TAS
    respiratory chain complex I GO:0045271 IBA
    respiratory chain complex I GO:0045271 IDA
    respiratory chain complex I GO:0045271 NAS
 Experiment description of studies that identified NDUFB10 in sEVs
1
Experiment ID 489
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for NDUFB10
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ATP6V1B2 526
Co-fractionation Homo sapiens
2 LIG4 3981
Two-hybrid Homo sapiens
3 CBX1 10951
Affinity Capture-MS Homo sapiens
4 PTPN22  
Affinity Capture-MS Homo sapiens
5 NDUFS1 4719
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
6 TPM2 7169
Co-fractionation Homo sapiens
7 FAM9B  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
8 NDUFB5 4711
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
9 KIF20A 10112
Affinity Capture-MS Homo sapiens
10 NDUFA12 55967
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
11 NDUFA4 4697
Affinity Capture-MS Homo sapiens
12 DNAJC15  
Proximity Label-MS Homo sapiens
13 CCDC90B  
Proximity Label-MS Homo sapiens
14 KIAA1429 25962
Affinity Capture-MS Homo sapiens
15 NDUFB9 4715
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
16 NDUFS3 4722
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 ATP5A1 498
Co-fractionation Homo sapiens
18 NDUFA7 4701
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
19 TIMMDC1  
Affinity Capture-MS Homo sapiens
20 TMED2 10959
Affinity Capture-MS Homo sapiens
21 HGS 9146
Two-hybrid Homo sapiens
22 NDUFA5 4698
Co-fractionation Homo sapiens
23 COA3 28958
Co-fractionation Homo sapiens
24 DDX58 23586
Affinity Capture-RNA Homo sapiens
25 SURF1  
Proximity Label-MS Homo sapiens
26 ATP5O 539
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
27 NDUFA8 4702
Co-fractionation Homo sapiens
28 NDUFV1 4723
Co-fractionation Homo sapiens
29 PHB 5245
Co-fractionation Homo sapiens
30 NDUFV3 4731
Affinity Capture-MS Homo sapiens
31 ATP5H 10476
Co-fractionation Homo sapiens
32 UQCC3  
Co-fractionation Homo sapiens
33 MYCN  
Affinity Capture-MS Homo sapiens
34 NDUFS5 4725
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
35 SLC25A3 5250
Co-fractionation Homo sapiens
36 FAS 355
Proximity Label-MS Homo sapiens
37 RNF181  
Two-hybrid Homo sapiens
38 NDUFB1 4707
Co-fractionation Homo sapiens
39 APOO 79135
Proximity Label-MS Homo sapiens
40 MRPL13  
Co-fractionation Homo sapiens
41 MTCH2 23788
Co-fractionation Homo sapiens
42 DNAJB8 165721
Affinity Capture-MS Homo sapiens
43 NDUFS4 4724
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
44 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
45 NDUFB7 4713
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
46 XRN1 54464
Two-hybrid Homo sapiens
47 SPARC 6678
Co-fractionation Homo sapiens
48 TUFM 7284
Co-fractionation Homo sapiens
49 DIABLO 56616
Proximity Label-MS Homo sapiens
50 TPM4 7171
Co-fractionation Homo sapiens
51 CCDC109B 55013
Proximity Label-MS Homo sapiens
52 CYC1 1537
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
53 MTMR1 8776
Affinity Capture-MS Homo sapiens
54 DNAJC30  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 AGPS 8540
Co-fractionation Homo sapiens
56 TMEM70  
Proximity Label-MS Homo sapiens
57 NDUFAF3 25915
Affinity Capture-MS Homo sapiens
58 ATP5B 506
Co-fractionation Homo sapiens
59 COX4I1 1327
Proximity Label-MS Homo sapiens
60 SLC25A24 29957
Co-fractionation Homo sapiens
61 HADHB 3032
Co-fractionation Homo sapiens
62 SLC25A12 8604
Proximity Label-MS Homo sapiens
63 AIFM1 9131
Proximity Label-MS Homo sapiens
64 CANX 821
Co-fractionation Homo sapiens
65 MCCC2 64087
Co-fractionation Homo sapiens
66 NDUFA13 51079
Affinity Capture-MS Homo sapiens
67 LRRC59 55379
Co-fractionation Homo sapiens
68 NDUFA9 4704
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
69 UQCRC2 7385
Co-fractionation Homo sapiens
70 MRPS7 51081
Co-fractionation Homo sapiens
71 BCAP31 10134
Co-fractionation Homo sapiens
72 RMND1 55005
Proximity Label-MS Homo sapiens
73 FKBP8 23770
Co-fractionation Homo sapiens
74 RIPK4  
Affinity Capture-MS Homo sapiens
75 MAPK6  
Affinity Capture-MS Homo sapiens
76 TPM1 7168
Co-fractionation Homo sapiens
77 NDUFB3 4709
Affinity Capture-MS Homo sapiens
78 COX6C 1345
Co-fractionation Homo sapiens
79 ACTB 60
Co-fractionation Homo sapiens
80 RCN2 5955
Co-fractionation Homo sapiens
81 VDAC1 7416
Co-fractionation Homo sapiens
82 NDUFV2 4729
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
83 NDUFC2 4718
Affinity Capture-MS Homo sapiens
84 MARC1  
Co-fractionation Homo sapiens
85 NDUFB11 54539
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
86 MCUR1 63933
Proximity Label-MS Homo sapiens
87 TPM3 7170
Co-fractionation Homo sapiens
88 NDUFA1 4694
Affinity Capture-MS Homo sapiens
89 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
90 PHB2 11331
Co-fractionation Homo sapiens
91 POLR1C 9533
Two-hybrid Homo sapiens
92 ALDH1B1 219
Co-fractionation Homo sapiens
93 COX5A 9377
Co-fractionation Homo sapiens
94 DNAJA3 9093
Proximity Label-MS Homo sapiens
95 Htt  
Affinity Capture-MS Mus musculus
96 PDHB 5162
Co-fractionation Homo sapiens
97 C21orf33  
Proximity Label-MS Homo sapiens
98 SFXN1 94081
Proximity Label-MS Homo sapiens
99 NIPSNAP1 8508
Co-fractionation Homo sapiens
100 NDUFS8 4728
Co-fractionation Homo sapiens
101 NDUFA2 4695
Co-fractionation Homo sapiens
102 YBX3 8531
Co-fractionation Homo sapiens
103 UPF1 5976
Two-hybrid Homo sapiens
104 SLC25A51  
Proximity Label-MS Homo sapiens
105 CORO1B 57175
Co-fractionation Homo sapiens
106 SERBP1 26135
Affinity Capture-MS Homo sapiens
107 PIK3R2 5296
Affinity Capture-MS Homo sapiens
108 NDUFAF4 29078
Affinity Capture-MS Homo sapiens
109 COX7C 1350
Co-fractionation Homo sapiens
110 C9orf72  
Affinity Capture-MS Homo sapiens
111 NDUFS6  
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
112 NDUFS7 374291
Co-fractionation Homo sapiens
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