Gene description for AZU1
Gene name	azurocidin 1
Gene symbol	AZU1
Other names/aliases	AZAMP AZU CAP37 HBP HUMAZUR NAZC
Species	Homo sapiens
Database cross references - AZU1
ExoCarta	ExoCarta_566
Vesiclepedia	VP_566
Entrez Gene	566
HGNC	913
MIM	162815
UniProt	P20160
AZU1 identified in sEVs derived from the following tissue/cell type
Urine	19056867

Gene ontology annotations for AZU1

Molecular Function     serine-type endopeptidase activity GO:0004252 IBA     protein binding GO:0005515 IPI     heparin binding GO:0008201 IMP     peptidase activity GO:0008233 IDA     toxic substance binding GO:0015643 NAS     heparan sulfate proteoglycan binding GO:0043395 IDA Biological Process     microglial cell activation GO:0001774 IEP     proteolysis GO:0006508 IDA     inflammatory response GO:0006954 NAS     phospholipase C-activating G protein-coupled receptor signaling pathway GO:0007200 TAS     glial cell migration GO:0008347 IDA     antimicrobial humoral response GO:0019730 IMP     positive regulation of fractalkine production GO:0032724 IDA     positive regulation of interleukin-1 beta production GO:0032731 IDA     positive regulation of tumor necrosis factor production GO:0032760 IDA     intracellular signal transduction GO:0035556 IMP     monocyte extravasation GO:0035696 IDA     monocyte activation GO:0042117 TAS     negative regulation of apoptotic process GO:0043066 NAS     regulation of vascular permeability GO:0043114 NAS     cellular extravasation GO:0045123 NAS     positive regulation of MHC class II biosynthetic process GO:0045348 IEP     positive regulation of cell adhesion GO:0045785 IDA     macrophage chemotaxis GO:0048246 NAS     positive regulation of phagocytosis GO:0050766 IDA     defense response to Gram-negative bacterium GO:0050829 TAS     induction of positive chemotaxis GO:0050930 NAS     protein maturation GO:0051604 IBA     defense response to virus GO:0051607 IMP     cell chemotaxis GO:0060326 IMP     neutrophil-mediated killing of bacterium GO:0070944 IDA Subcellular Localization     extracellular region GO:0005576 NAS     extracellular region GO:0005576 TAS     extracellular space GO:0005615 IBA     extracellular space GO:0005615 IDA     membrane GO:0016020 IDA     azurophil granule membrane GO:0035577 IDA     azurophil granule lumen GO:0035578 TAS     azurophil granule GO:0042582 IDA     intracellular membrane-bounded organelle GO:0043231 IDA     extracellular exosome GO:0070062 HDA