Gene description for Ilf2
Gene name interleukin enhancer binding factor 2
Gene symbol Ilf2
Other names/aliases 6230405A16Rik
TEG-267
Tex261
Tex267
Species Mus musculus
 Database cross references - Ilf2
ExoCarta ExoCarta_67781
Vesiclepedia VP_67781
Entrez Gene 67781
UniProt Q9CXY6  
 Ilf2 identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Ilf2
Molecular Function
    DNA binding GO:0003677 IBA
    DNA binding GO:0003677 ISO
    DNA binding GO:0003677 ISS
    double-stranded RNA binding GO:0003725 IBA
    double-stranded RNA binding GO:0003725 ISO
    double-stranded RNA binding GO:0003725 ISS
Biological Process
    positive regulation of DNA-templated transcription GO:0045893 IBA
    positive regulation of DNA-templated transcription GO:0045893 ISO
    positive regulation of DNA-templated transcription GO:0045893 ISS
Subcellular Localization
    nucleus GO:0005634 IDA
    nucleus GO:0005634 ISO
    nucleus GO:0005634 ISS
    nucleoplasm GO:0005654 IEA
    nucleoplasm GO:0005654 ISO
    nucleolus GO:0005730 IDA
    nucleolus GO:0005730 ISO
    nucleolus GO:0005730 ISS
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
    ribonucleoprotein complex GO:1990904 ISO
    ribonucleoprotein complex GO:1990904 ISS
 Experiment description of studies that identified Ilf2 in sEVs
1
Experiment ID 907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Ilf2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Hnrnpl 15388
Co-fractionation Mus musculus
2 Zbtb7b  
Affinity Capture-MS Mus musculus
3 Eprs 107508
Co-fractionation Mus musculus
4 Fxr1 14359
Affinity Capture-MS Mus musculus
5 Ncbp1 433702
Co-fractionation Mus musculus
6 Fzr1  
Affinity Capture-MS Mus musculus
7 Atxn1  
Affinity Capture-MS Mus musculus
8 Eed  
Affinity Capture-MS Mus musculus
9 MKRN1 23608
Affinity Capture-MS Homo sapiens
10 Plrg1  
Co-fractionation Mus musculus
11 Ago2 239528
Co-fractionation Mus musculus
12 Hnrnpd 11991
Co-fractionation Mus musculus
13 Atg16l1  
Affinity Capture-MS Mus musculus
14 SGSM2  
Two-hybrid Homo sapiens
15 Pou5f1  
Affinity Capture-MS Mus musculus
16 Ncl 17975
Co-fractionation Mus musculus
17 Hnrnpab 15384
Co-fractionation Mus musculus
18 Nanog  
Affinity Capture-MS Mus musculus
19 Pabpn1 54196
Co-fractionation Mus musculus
20 Kctd13  
Affinity Capture-MS Mus musculus
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