Gene description for St13
Gene name suppression of tumorigenicity 13
Gene symbol St13
Other names/aliases 1110007I03Rik
3110002K08Rik
AW555194
HIP
HOP
HSPABP
HSPABP1
PRO0786
SNC6
p48
Species Mus musculus
 Database cross references - St13
ExoCarta ExoCarta_70356
Vesiclepedia VP_70356
Entrez Gene 70356
UniProt Q99L47  
 St13 identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for St13
Molecular Function
    protein domain specific binding GO:0019904 ISO
    Hsp70 protein binding GO:0030544 IBA
    Hsp70 protein binding GO:0030544 ISO
    dATP binding GO:0032564 ISO
    identical protein binding GO:0042802 ISO
    protein-containing complex binding GO:0044877 ISO
    protein dimerization activity GO:0046983 IEA
    unfolded protein binding GO:0051082 ISO
    protein-folding chaperone binding GO:0051087 ISO
Biological Process
    response to bacterium GO:0009617 IEP
    chaperone cofactor-dependent protein refolding GO:0051085 IBA
    chaperone cofactor-dependent protein refolding GO:0051085 ISO
    negative regulation of protein refolding GO:0061084 ISO
Subcellular Localization
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
    protein-containing complex GO:0032991 ISO
 Experiment description of studies that identified St13 in sEVs
1
Experiment ID 907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for St13
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Dpysl3 22240
Co-fractionation Mus musculus
2 Pcbd1  
Co-fractionation Mus musculus
3 Apoe 11816
Co-fractionation Mus musculus
4 Bag1  
Co-fractionation Mus musculus
5 Kctd13  
Affinity Capture-MS Mus musculus
6 Xrcc6  
Co-fractionation Mus musculus
7 F2  
Co-fractionation Mus musculus
8 Chaf1a  
Affinity Capture-MS Mus musculus
9 Dapk1  
Co-fractionation Mus musculus
10 Twist1  
Proximity Label-MS Mus musculus
View the network image/svg+xml



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