Gene description for TNFSF12
Gene name	tumor necrosis factor (ligand) superfamily, member 12
Gene symbol	TNFSF12
Other names/aliases	APO3L DR3LG TWEAK
Species	Homo sapiens
Database cross references - TNFSF12
ExoCarta	ExoCarta_8742
Vesiclepedia	VP_8742
Entrez Gene	8742
HGNC	11927
MIM	602695
UniProt	O43508
TNFSF12 identified in sEVs derived from the following tissue/cell type
Saliva	19199708

Gene ontology annotations for TNFSF12

Molecular Function     signaling receptor binding GO:0005102 TAS     cytokine activity GO:0005125 IEA     cytokine activity GO:0005125 TAS     tumor necrosis factor receptor binding GO:0005164 IEA     protein binding GO:0005515 IPI     receptor ligand activity GO:0048018 IBA Biological Process     angiogenesis GO:0001525 IEA     positive regulation of endothelial cell proliferation GO:0001938 TAS     apoptotic process GO:0006915 TAS     immune response GO:0006955 IEA     signal transduction GO:0007165 TAS     cell differentiation GO:0030154 IEA     endothelial cell migration GO:0043542 TAS     positive regulation of protein catabolic process GO:0045732 IDA     positive regulation of angiogenesis GO:0045766 TAS     apoptotic signaling pathway GO:0097190 TAS     extrinsic apoptotic signaling pathway GO:0097191 IBA     positive regulation of extrinsic apoptotic signaling pathway GO:2001238 IDA Subcellular Localization     extracellular region GO:0005576 TAS     extracellular space GO:0005615 IBA     extracellular space GO:0005615 TAS     plasma membrane GO:0005886 TAS     perinuclear region of cytoplasm GO:0048471 IDA