Gene ontology annotations for METAP2
Experiment description of studies that identified METAP2 in sEVs
1
Experiment ID
489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 6
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
2
Experiment ID
490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 7
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
3
Experiment ID
491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 8
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
4
Experiment ID
492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 9
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
5
Experiment ID
412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Breast cancer cells
Sample name
MCF7
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
6
Experiment ID
414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Breast cancer cells
Sample name
MDA-MB-231
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
7
Experiment ID
426
MISEV standards
✘
Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Breast cancer cells
Sample name
MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
8
Experiment ID
427
MISEV standards
✘
Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Breast cancer cells
Sample name
MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
9
Experiment ID
497
MISEV standards
✘
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35931686
Organism
Homo sapiens
Experiment description
Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors
"Varela-EirÃÂn M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, GarcÃÂa-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name
Cell Death Dis
Publication year
2022
Sample
Chondrocytes
Sample name
T/C-28a2
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
10
Experiment ID
498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35931686
Organism
Homo sapiens
Experiment description
Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors
"Varela-EirÃÂn M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, GarcÃÂa-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name
Cell Death Dis
Publication year
2022
Sample
Chondrocytes
Sample name
T/C-28a2
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
11
Experiment ID
207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23161513
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors
"Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name
Mol Cell Proteomics
Publication year
2012
Sample
Colorectal cancer cells
Sample name
DKO-1
Isolation/purification methods
Differential centrifugation Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
12
Experiment ID
208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23161513
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors
"Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name
Mol Cell Proteomics
Publication year
2012
Sample
Colorectal cancer cells
Sample name
Dks-8
Isolation/purification methods
Differential centrifugation Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
13
Experiment ID
209
MISEV standards
✘
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23161513
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors
"Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name
Mol Cell Proteomics
Publication year
2012
Sample
Colorectal cancer cells
Sample name
DLD-1
Isolation/purification methods
Differential centrifugation Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
14
Experiment ID
407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Embryonic kidney cells
Sample name
HEK293T
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
15
Experiment ID
419
MISEV standards
✘
Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Embryonic kidney cells
Sample name
HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
16
Experiment ID
419
MISEV standards
✘
Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Embryonic kidney cells
Sample name
HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
17
Experiment ID
420
MISEV standards
✘
Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Embryonic kidney cells
Sample name
HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
18
Experiment ID
420
MISEV standards
✘
Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Embryonic kidney cells
Sample name
HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
19
Experiment ID
405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Foreskin fibroblasts
Sample name
BJ
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
20
Experiment ID
417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Lymphoma cells
Sample name
Raji
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
21
Experiment ID
411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Mammary cancer-associated fibroblasts
Sample name
mCAF
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
22
Experiment ID
488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Homo sapiens
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Mesenchymal stem cells
Sample name
UCMSC
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
23
Experiment ID
418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Monocytic leukemia cells
Sample name
THP-1
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
24
Experiment ID
413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Normal mammary epithelial cells
Sample name
MCF10A
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
25
Experiment ID
211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
"Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
IGROV1
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
26
Experiment ID
212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
"Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
OVCAR-3
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
27
Experiment ID
406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Pancreatic cancer cells
Sample name
BxPC3
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
28
Experiment ID
415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Pancreatic cancer cells
Sample name
PANC-1
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
29
Experiment ID
434
MISEV standards
✘
Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Pancreatic cancer cells
Sample name
PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
30
Experiment ID
435
MISEV standards
✘
Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Pancreatic cancer cells
Sample name
PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
31
Experiment ID
408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Pancreatic duct epithalial cells
Sample name
HPDE
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
32
Experiment ID
409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Pancreatic duct epithalial cells
Sample name
HPNE
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
33
Experiment ID
416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Pluripotent stem cells
Sample name
PSC
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
34
Experiment ID
191
MISEV standards
✘
Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
20124223
Organism
Homo sapiens
Experiment description
Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors
"Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name
Mol Cell Proteomics
Publication year
2010
Sample
Squamous carcinoma cells
Sample name
Squamous carcinoma cell (A431)
Isolation/purification methods
Differential centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
35
Experiment ID
410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
T lymphocytes
Sample name
Jurkat
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
Protein-protein interactions for METAP2
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
GNL2
29889
Affinity Capture-MS
Homo sapiens
2
RPSA
3921
Affinity Capture-MS
Homo sapiens
3
RPL14
9045
Affinity Capture-MS
Homo sapiens
4
RIT1
6016
Negative Genetic
Homo sapiens
5
NPEPPS
9520
Co-fractionation
Homo sapiens
6
RPL26L1
51121
Affinity Capture-MS
Homo sapiens
7
EIF3A
8661
Affinity Capture-MS
Homo sapiens
8
CCT3
7203
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
9
RPS3A
6189
Affinity Capture-MS
Homo sapiens
10
VAPA
9218
Affinity Capture-MS
Homo sapiens
11
EIF2S3
1968
Affinity Capture-MS
Homo sapiens
12
EIF3K
27335
Affinity Capture-MS
Homo sapiens
13
RPS17
6218
Affinity Capture-MS
Homo sapiens
14
SRPRB
58477
Affinity Capture-MS
Homo sapiens
15
DLK2
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
16
YWHAE
7531
Reconstituted Complex
Homo sapiens
17
RPL13A
23521
Affinity Capture-MS
Homo sapiens
18
RPL37A
6168
Affinity Capture-MS
Homo sapiens
19
PDE4A
5141
Affinity Capture-MS
Homo sapiens
20
RPS19
6223
Affinity Capture-MS
Homo sapiens
21
RPL10
6134
Affinity Capture-MS
Homo sapiens
22
RPL15
6138
Affinity Capture-MS
Homo sapiens
23
LAD1
3898
Affinity Capture-MS
Homo sapiens
24
ALDH5A1
7915
Affinity Capture-MS
Homo sapiens
25
EIF4A1
1973
Affinity Capture-MS
Homo sapiens
26
CCT6B
10693
Affinity Capture-MS
Homo sapiens
27
EIF3G
8666
Affinity Capture-MS
Homo sapiens
28
Fgfr1
14182
Affinity Capture-MS
Mus musculus
29
CCDC124
115098
Affinity Capture-MS
Homo sapiens
30
APP
351
Reconstituted Complex
Homo sapiens
31
FAU
2197
Affinity Capture-MS
Homo sapiens
32
RPS3
6188
Affinity Capture-MS
Homo sapiens
33
JAZF1
Affinity Capture-MS
Homo sapiens
34
SEZ6
Affinity Capture-MS
Homo sapiens
35
RPS18
6222
Affinity Capture-MS
Homo sapiens
36
SRP54
6729
Affinity Capture-MS
Homo sapiens
37
RPS6
6194
Affinity Capture-MS
Homo sapiens
38
RPL4
6124
Affinity Capture-MS
Homo sapiens
39
RPS20
6224
Affinity Capture-MS
Homo sapiens
40
IGF2BP3
10643
Affinity Capture-MS
Homo sapiens
41
NKRF
55922
Affinity Capture-MS
Homo sapiens
42
RPL39
6170
Affinity Capture-MS
Homo sapiens
43
H1FX
8971
Affinity Capture-MS
Homo sapiens
44
EIF3B
8662
Affinity Capture-MS
Homo sapiens
45
RPN1
6184
Affinity Capture-MS
Homo sapiens
46
RPL24
6152
Affinity Capture-MS
Homo sapiens
47
RPL18
6141
Affinity Capture-MS
Homo sapiens
48
RPL36
25873
Affinity Capture-MS
Homo sapiens
49
LSG1
Affinity Capture-MS
Homo sapiens
50
TNFRSF19
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
51
SSR1
6745
Affinity Capture-MS
Homo sapiens
52
RPS5
6193
Affinity Capture-MS
Homo sapiens
53
RPS9
6203
Affinity Capture-MS
Homo sapiens
54
PLIN5
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
55
TEKT2
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
56
EIF3E
3646
Affinity Capture-MS
Homo sapiens
57
CWF19L1
55280
Affinity Capture-MS
Homo sapiens
58
SUN2
25777
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
59
TMEM108
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
60
FCRL2
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
61
SRP68
6730
Affinity Capture-MS
Homo sapiens
62
RPL29
6159
Affinity Capture-MS
Homo sapiens
63
ATG16L1
55054
Affinity Capture-MS
Homo sapiens
64
SLC25A25
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
65
MTDH
92140
Affinity Capture-MS
Homo sapiens
66
RPL34
6164
Affinity Capture-MS
Homo sapiens
67
MECP2
4204
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
68
CTPS1
1503
Affinity Capture-MS
Homo sapiens
69
CHD3
1107
Co-fractionation
Homo sapiens
70
C1QTNF9B
Affinity Capture-MS
Homo sapiens
71
HK1
3098
Affinity Capture-MS
Homo sapiens
72
PABPC4
8761
Affinity Capture-MS
Homo sapiens
73
CKMT2
Affinity Capture-MS
Homo sapiens
74
KIF14
9928
Affinity Capture-MS
Homo sapiens
75
RPS14
6208
Affinity Capture-MS
Homo sapiens
76
ATXN2
6311
Affinity Capture-MS
Homo sapiens
77
CCT2
10576
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
78
BSG
682
Affinity Capture-MS
Homo sapiens
79
RPS23
6228
Affinity Capture-MS
Homo sapiens
80
EIF2AK2
5610
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
81
ATAD1
84896
Affinity Capture-MS
Homo sapiens
82
RPL30
6156
Affinity Capture-MS
Homo sapiens
83
RGS2
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
84
USP10
9100
Affinity Capture-MS
Homo sapiens
85
RPL9
6133
Affinity Capture-MS
Homo sapiens
86
NDUFB7
4713
Affinity Capture-MS
Homo sapiens
87
TMEM213
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
88
PARK2
Affinity Capture-MS
Homo sapiens
89
RBM28
55131
Affinity Capture-MS
Homo sapiens
90
RPS10
6204
Affinity Capture-MS
Homo sapiens
91
STAU1
6780
Affinity Capture-MS
Homo sapiens
92
CCT5
22948
Affinity Capture-MS
Homo sapiens
93
RPL5
6125
Affinity Capture-MS
Homo sapiens
94
PABPC1
26986
Affinity Capture-MS
Homo sapiens
95
C1QTNF9
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
96
OGT
8473
Reconstituted Complex
Homo sapiens
97
RPL31
6160
Affinity Capture-MS
Homo sapiens
98
ACTL6A
86
Affinity Capture-MS
Homo sapiens
99
SYNCRIP
10492
Affinity Capture-MS
Homo sapiens
100
NCL
4691
Affinity Capture-MS
Homo sapiens
101
NOMO3
408050
Affinity Capture-MS
Homo sapiens
102
RPL27A
6157
Affinity Capture-MS
Homo sapiens
103
RPLP1
6176
Affinity Capture-MS
Homo sapiens
104
LYAR
55646
Affinity Capture-MS
Homo sapiens
105
GPBP1L1
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
106
DHX9
1660
Affinity Capture-MS
Homo sapiens
107
RPLP0
6175
Affinity Capture-MS
Homo sapiens
108
RPS16
6217
Affinity Capture-MS
Homo sapiens
109
PELP1
27043
Affinity Capture-MS
Homo sapiens
110
EN1
Affinity Capture-MS
Homo sapiens
111
RPS15A
6210
Affinity Capture-MS
Homo sapiens
112
CEBPA
Protein-peptide
Homo sapiens
113
GTPBP4
23560
Affinity Capture-MS
Homo sapiens
114
RPL11
6135
Affinity Capture-MS
Homo sapiens
115
LARP1
23367
Affinity Capture-MS
Homo sapiens
116
GRIA3
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
117
NTRK1
4914
Affinity Capture-MS
Homo sapiens
118
RPL32
6161
Affinity Capture-MS
Homo sapiens
119
DDX6
1656
Affinity Capture-MS
Homo sapiens
120
RDH14
57665
Affinity Capture-MS
Homo sapiens
121
DNAJC27
Affinity Capture-MS
Homo sapiens
122
IL31
Affinity Capture-MS
Homo sapiens
123
RPL7A
6130
Affinity Capture-MS
Homo sapiens
124
RPS2
6187
Affinity Capture-MS
Homo sapiens
125
XPO1
7514
Affinity Capture-MS
Homo sapiens
126
MRPL35
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
127
RPL35
11224
Affinity Capture-MS
Homo sapiens
128
DHX29
54505
Affinity Capture-MS
Homo sapiens
129
RPL21
6144
Affinity Capture-MS
Homo sapiens
130
ASB6
140459
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
131
HSP90AB1
3326
Cross-Linking-MS (XL-MS)
Homo sapiens
132
RPS7
6201
Affinity Capture-MS
Homo sapiens
133
CTTN
2017
Affinity Capture-MS
Homo sapiens
134
RPL3
6122
Affinity Capture-MS
Homo sapiens
135
EIF4E
1977
Affinity Capture-MS
Homo sapiens
136
DHX30
22907
Affinity Capture-MS
Homo sapiens
137
TMEM194A
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
138
OPRL1
4987
Affinity Capture-MS
Homo sapiens
139
EIF2S2
8894
Affinity Capture-MS
Homo sapiens
140
RPL7
6129
Affinity Capture-MS
Homo sapiens
141
RIPK4
Affinity Capture-MS
Homo sapiens
142
CALM1
801
Reconstituted Complex
Homo sapiens
143
RPS27
6232
Affinity Capture-MS
Homo sapiens
144
C1QB
713
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
145
NOB1
Affinity Capture-MS
Homo sapiens
146
GNAS
2778
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
147
RARRES1
5918
Affinity Capture-MS
Homo sapiens
148
C11orf98
Affinity Capture-MS
Homo sapiens
149
MTOR
2475
Affinity Capture-Western
Homo sapiens
150
PRRC2A
7916
Affinity Capture-MS
Homo sapiens
151
RPL35A
6165
Affinity Capture-MS
Homo sapiens
152
RPL12
6136
Affinity Capture-MS
Homo sapiens
153
RPL22
6146
Affinity Capture-MS
Homo sapiens
154
EIF3CL
728689
Affinity Capture-MS
Homo sapiens
155
FAM195B
348262
Affinity Capture-MS
Homo sapiens
156
HYOU1
10525
Affinity Capture-MS
Homo sapiens
157
PVR
5817
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
158
RPS11
6205
Affinity Capture-MS
Homo sapiens
159
KTN1
3895
Affinity Capture-MS
Homo sapiens
160
LRRC37B
Affinity Capture-MS
Homo sapiens
161
TKFC
26007
Co-fractionation
Homo sapiens
162
LPPR2
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
163
EEF2K
Affinity Capture-MS
Homo sapiens
164
EIF4G2
1982
Affinity Capture-MS
Homo sapiens
165
RPLP2
6181
Affinity Capture-MS
Homo sapiens
166
GNL3
26354
Affinity Capture-MS
Homo sapiens
167
EIF3D
8664
Affinity Capture-MS
Homo sapiens
168
EIF3H
8667
Affinity Capture-MS
Homo sapiens
169
RPL19
6143
Affinity Capture-MS
Homo sapiens
170
RPL13
6137
Affinity Capture-MS
Homo sapiens
171
EIF2S1
1965
Affinity Capture-MS
Homo sapiens
172
RSPH1
Affinity Capture-MS
Homo sapiens
173
GLUD1
2746
Affinity Capture-MS
Homo sapiens
174
PCBD2
84105
Affinity Capture-MS
Homo sapiens
175
RPS25
6230
Affinity Capture-MS
Homo sapiens
176
EIF3C
8663
Affinity Capture-MS
Homo sapiens
177
STAC2
Affinity Capture-MS
Homo sapiens
178
ILF3
3609
Affinity Capture-MS
Homo sapiens
179
GBP1
2633
Co-fractionation
Homo sapiens
180
RPL6
6128
Affinity Capture-MS
Homo sapiens
181
RPS21
6227
Affinity Capture-MS
Homo sapiens
182
EIF3I
8668
Affinity Capture-MS
Homo sapiens
183
LILRB3
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
184
EIF4G1
1981
Affinity Capture-MS
Homo sapiens
185
NUFIP2
57532
Affinity Capture-MS
Homo sapiens
186
CUL5
8065
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
187
RPS12
6206
Affinity Capture-MS
Homo sapiens
188
RPS4X
6191
Affinity Capture-MS
Homo sapiens
189
RPS15
6209
Affinity Capture-MS
Homo sapiens
190
C1orf35
Affinity Capture-MS
Homo sapiens
191
SESN2
83667
Affinity Capture-Western
Homo sapiens
192
SRP72
6731
Affinity Capture-MS
Homo sapiens
193
CAPRIN1
4076
Affinity Capture-MS
Homo sapiens
194
SUCLA2
8803
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
195
GNB1
2782
Affinity Capture-MS
Homo sapiens
196
FMNL3
91010
Affinity Capture-MS
Homo sapiens
197
PRRC2B
Affinity Capture-MS
Homo sapiens
198
OTUD6B
51633
Affinity Capture-MS
Homo sapiens
199
CCT7
10574
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
200
RNF7
Affinity Capture-MS
Homo sapiens
201
RPS26
6231
Affinity Capture-MS
Homo sapiens
202
DRG1
4733
Affinity Capture-MS
Homo sapiens
203
RPS28
6234
Affinity Capture-MS
Homo sapiens
204
RPL10A
4736
Affinity Capture-MS
Homo sapiens
205
HSPBP1
23640
Affinity Capture-MS
Homo sapiens
206
RPL38
6169
Affinity Capture-MS
Homo sapiens
207
RPS24
6229
Affinity Capture-MS
Homo sapiens
208
GAPDH
2597
Co-fractionation
Homo sapiens
209
EIF3M
10480
Affinity Capture-MS
Homo sapiens
210
EIF4B
1975
Affinity Capture-MS
Homo sapiens
211
UPF1
5976
Affinity Capture-MS
Homo sapiens
212
RPS8
6202
Affinity Capture-MS
Homo sapiens
213
RPL8
6132
Affinity Capture-MS
Homo sapiens
214
RPL27
6155
Affinity Capture-MS
Homo sapiens
215
RPL28
6158
Affinity Capture-MS
Homo sapiens
216
RPS27L
51065
Affinity Capture-MS
Homo sapiens
217
SERBP1
26135
Affinity Capture-MS
Homo sapiens
218
RPL23A
6147
Affinity Capture-MS
Homo sapiens
219
KRAS
3845
Negative Genetic
Homo sapiens
220
GNB2L1
10399
Affinity Capture-MS
Homo sapiens
221
DNMT1
1786
Co-fractionation
Homo sapiens
222
SNX29
Affinity Capture-MS
Homo sapiens
223
ABCE1
6059
Affinity Capture-MS
Homo sapiens
224
DDX28
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
225
RPL17
6139
Affinity Capture-MS
Homo sapiens
226
EIF3L
51386
Affinity Capture-MS
Homo sapiens
227
RPS13
6207
Affinity Capture-MS
Homo sapiens
View the network
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Pathways in which METAP2 is involved