Gene description for RPL35A
Gene name ribosomal protein L35a
Gene symbol RPL35A
Other names/aliases DBA5
L35A
Species Homo sapiens
 Database cross references - RPL35A
ExoCarta ExoCarta_6165
Vesiclepedia VP_6165
Entrez Gene 6165
HGNC 10345
MIM 180468
UniProt P18077  
 RPL35A identified in sEVs derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 36706192    
Embryonic kidney cells 36706192    
Foreskin fibroblasts 34108659    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocytes 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells Unpublished / Not applicable
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for RPL35A
Molecular Function
    tRNA binding GO:0000049 IEA
    RNA binding GO:0003723 HDA
    structural constituent of ribosome GO:0003735 IBA
    structural constituent of ribosome GO:0003735 IDA
    structural constituent of ribosome GO:0003735 IMP
    structural constituent of ribosome GO:0003735 NAS
    protein binding GO:0005515 IPI
Biological Process
    cytoplasmic translation GO:0002181 IBA
    cytoplasmic translation GO:0002181 IC
    cytoplasmic translation GO:0002181 NAS
    rRNA processing GO:0006364 IMP
    translation GO:0006412 NAS
    ribosomal large subunit biogenesis GO:0042273 IBA
    ribosomal large subunit biogenesis GO:0042273 IMP
Subcellular Localization
    cytoplasm GO:0005737 NAS
    cytosol GO:0005829 TAS
    membrane GO:0016020 HDA
    cytosolic large ribosomal subunit GO:0022625 HDA
    cytosolic large ribosomal subunit GO:0022625 IBA
    cytosolic large ribosomal subunit GO:0022625 IDA
    cytosolic large ribosomal subunit GO:0022625 IPI
    cytosolic ribosome GO:0022626 IDA
    synapse GO:0045202 IEA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified RPL35A in sEVs
1
Experiment ID 79
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 80
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
3
Experiment ID 489
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 490
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 491
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 492
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 412
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
8
Experiment ID 414
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
9
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
10
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
12
Experiment ID 498
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
13
Experiment ID 207
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 208
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 407
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
20
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
21
Experiment ID 1275
MISEV standards
Biophysical techniques
✔ Enriched markers
✔ Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 1280
MISEV standards
Biophysical techniques
✔ Enriched markers
✔ Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T - Fraction 5
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density 1.151 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 405
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 234
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-C3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
25
Experiment ID 235
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
26
Experiment ID 236
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
27
Experiment ID 237
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
28
Experiment ID 417
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 411
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
31
Experiment ID 488
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
32
Experiment ID 418
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
33
Experiment ID 413
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
34
Experiment ID 406
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 415
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
37
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
38
Experiment ID 408
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
39
Experiment ID 409
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
40
Experiment ID 416
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
41
Experiment ID 834
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
42
Experiment ID 835
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
43
Experiment ID 410
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
44
Experiment ID 217
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RPL35A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RAC3 5881
Affinity Capture-MS Homo sapiens
2 RPSA 3921
Co-fractionation Homo sapiens
3 RALY 22913
Affinity Capture-MS Homo sapiens
4 SRP19 6728
Affinity Capture-MS Homo sapiens
5 MLLT4 4301
Affinity Capture-MS Homo sapiens
6 UBE2H 7328
Affinity Capture-MS Homo sapiens
7 RAD21 5885
Two-hybrid Homo sapiens
8 RPL26L1 51121
Affinity Capture-MS Homo sapiens
9 CD3EAP  
Affinity Capture-MS Homo sapiens
10 PPP2R5D 5528
Affinity Capture-MS Homo sapiens
11 SPPL3  
Affinity Capture-MS Homo sapiens
12 WDR3  
Affinity Capture-MS Homo sapiens
13 DNAJC8 22826
Proximity Label-MS Homo sapiens
14 RPS3A 6189
Co-fractionation Homo sapiens
15 COX15 1355
Affinity Capture-MS Homo sapiens
16 KIAA0020 9933
Affinity Capture-MS Homo sapiens
17 PPIE 10450
Affinity Capture-MS Homo sapiens
18 ACAA1 30
Affinity Capture-MS Homo sapiens
19 SH3GL1 6455
Affinity Capture-MS Homo sapiens
20 BTF3 689
Affinity Capture-MS Homo sapiens
21 PRPF38B 55119
Affinity Capture-MS Homo sapiens
22 RPL13A 23521
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
23 OXSR1 9943
Affinity Capture-MS Homo sapiens
24 ACTC1 70
Affinity Capture-MS Homo sapiens
25 FBXL19  
Affinity Capture-MS Homo sapiens
26 NOP56 10528
Affinity Capture-MS Homo sapiens
27 GTF2F1 2962
Affinity Capture-MS Homo sapiens
28 RPS19 6223
Co-fractionation Homo sapiens
29 RPL10 6134
Co-fractionation Homo sapiens
30 KIF20A 10112
Affinity Capture-MS Homo sapiens
31 S100A7 6278
Affinity Capture-MS Homo sapiens
32 RPL14 9045
Co-fractionation Homo sapiens
33 CAND1 55832
Affinity Capture-MS Homo sapiens
34 SCAF4 57466
Affinity Capture-MS Homo sapiens
35 RBM12 10137
Affinity Capture-MS Homo sapiens
36 PTPN1 5770
Affinity Capture-MS Homo sapiens
37 PRPF40A 55660
Affinity Capture-MS Homo sapiens
38 SOX2  
Affinity Capture-MS Homo sapiens
39 SBDS 51119
Affinity Capture-MS Homo sapiens
40 EEF1A2 1917
Affinity Capture-MS Homo sapiens
41 WDR36 134430
Affinity Capture-MS Homo sapiens
42 RPS3 6188
Co-fractionation Homo sapiens
43 HNRNPUL2 221092
Co-fractionation Homo sapiens
44 ATG13 9776
Affinity Capture-MS Homo sapiens
45 RPS18 6222
Co-fractionation Homo sapiens
46 PTRH2 51651
Affinity Capture-MS Homo sapiens
47 XRCC1 7515
Affinity Capture-MS Homo sapiens
48 PARK2  
Affinity Capture-MS Homo sapiens
49 RPS20 6224
Co-fractionation Homo sapiens
50 METAP2 10988
Affinity Capture-MS Homo sapiens
51 PSMG3 84262
Affinity Capture-MS Homo sapiens
52 RNPS1 10921
Co-fractionation Homo sapiens
53 B3GNT2 10678
Affinity Capture-MS Homo sapiens
54 RPL39 6170
Co-fractionation Homo sapiens
55 PRC1 9055
Affinity Capture-MS Homo sapiens
56 ZBTB10 65986
Affinity Capture-MS Homo sapiens
57 KIF23 9493
Affinity Capture-MS Homo sapiens
58 MCM2 4171
Affinity Capture-MS Homo sapiens
59 HIBCH 26275
Affinity Capture-MS Homo sapiens
60 TLN1 7094
Affinity Capture-MS Homo sapiens
61 HARS2 23438
Affinity Capture-MS Homo sapiens
62 HDLBP 3069
Affinity Capture-MS Homo sapiens
63 FBXW7  
Affinity Capture-MS Homo sapiens
64 RPL24 6152
Co-fractionation Homo sapiens
65 SNX27 81609
Affinity Capture-MS Homo sapiens
66 MDC1  
Affinity Capture-MS Homo sapiens
67 RECQL4  
Affinity Capture-MS Homo sapiens
68 HIST1H2AI 8329
Affinity Capture-MS Homo sapiens
69 RPS5 6193
Co-fractionation Homo sapiens
70 RPS9 6203
Co-fractionation Homo sapiens
71 ABCE1 6059
Affinity Capture-MS Homo sapiens
72 ADARB1 104
Affinity Capture-MS Homo sapiens
73 UBP1 7342
Affinity Capture-MS Homo sapiens
74 PRKRA 8575
Affinity Capture-MS Homo sapiens
75 SMCHD1 23347
Affinity Capture-MS Homo sapiens
76 CHORDC1 26973
Affinity Capture-MS Homo sapiens
77 BRD4 23476
Affinity Capture-MS Homo sapiens
78 SRP68 6730
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
79 BLVRB 645
Affinity Capture-MS Homo sapiens
80 ATG3 64422
Affinity Capture-MS Homo sapiens
81 EIF2A 83939
Affinity Capture-MS Homo sapiens
82 Eif3a 13669
Affinity Capture-MS Mus musculus
83 CUL1 8454
Affinity Capture-MS Homo sapiens
84 PKN2 5586
Affinity Capture-MS Homo sapiens
85 ARIH2 10425
Affinity Capture-MS Homo sapiens
86 RPS11 6205
Co-fractionation Homo sapiens
87 RECQL 5965
Affinity Capture-MS Homo sapiens
88 RPL19 6143
Co-fractionation Homo sapiens
89 MTERF3  
Proximity Label-MS Homo sapiens
90 RBM8A 9939
Affinity Capture-MS Homo sapiens
91 KIF14 9928
Affinity Capture-MS Homo sapiens
92 FEN1 2237
Affinity Capture-MS Homo sapiens
93 LIN28A  
Affinity Capture-MS Homo sapiens
94 EMC9  
Affinity Capture-MS Homo sapiens
95 CHMP4C 92421
Affinity Capture-MS Homo sapiens
96 RAB5A 5868
Affinity Capture-MS Homo sapiens
97 RPL27 6155
Co-fractionation Homo sapiens
98 CYB5R3 1727
Affinity Capture-MS Homo sapiens
99 SH3GL3  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
100 DBNL 28988
Affinity Capture-MS Homo sapiens
101 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
102 UBE2T  
Affinity Capture-MS Homo sapiens
103 RPL9 6133
Co-fractionation Homo sapiens
104 RAB5B 5869
Affinity Capture-MS Homo sapiens
105 CUL4B 8450
Affinity Capture-MS Homo sapiens
106 RPL4 6124
Co-fractionation Homo sapiens
107 DRG1 4733
Affinity Capture-MS Homo sapiens
108 RRP9 9136
Cross-Linking-MS (XL-MS) Homo sapiens
109 TMOD1  
Affinity Capture-MS Homo sapiens
110 TBCE 6905
Affinity Capture-MS Homo sapiens
111 SYMPK 8189
Affinity Capture-MS Homo sapiens
112 RPL5 6125
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
113 RAB4A 5867
Affinity Capture-MS Homo sapiens
114 SRRT 51593
Affinity Capture-MS Homo sapiens
115 RTF1 23168
Co-fractionation Homo sapiens
116 VRK1 7443
Affinity Capture-MS Homo sapiens
117 HSCB 150274
Proximity Label-MS Homo sapiens
118 RPL18A 6142
Co-fractionation Homo sapiens
119 PTPN21 11099
Cross-Linking-MS (XL-MS) Homo sapiens
120 RAP1B 5908
Affinity Capture-MS Homo sapiens
121 CCDC51 79714
Affinity Capture-MS Homo sapiens
122 RPA2 6118
Proximity Label-MS Homo sapiens
123 PDS5A 23244
Affinity Capture-MS Homo sapiens
124 RPS10 6204
Co-fractionation Homo sapiens
125 ALDH6A1 4329
Affinity Capture-MS Homo sapiens
126 CKAP5 9793
Affinity Capture-MS Homo sapiens
127 RPL31 6160
Co-fractionation Homo sapiens
128 SAR1B 51128
Affinity Capture-MS Homo sapiens
129 EFHD1  
Affinity Capture-MS Homo sapiens
130 ARNT 405
Affinity Capture-MS Homo sapiens
131 RAP1A 5906
Affinity Capture-MS Homo sapiens
132 API5 8539
Affinity Capture-MS Homo sapiens
133 RPL36 25873
Co-fractionation Homo sapiens
134 RPL27A 6157
Co-fractionation Homo sapiens
135 ACTB 60
Affinity Capture-MS Homo sapiens
136 TPP2 7174
Affinity Capture-MS Homo sapiens
137 EIF4G2 1982
Affinity Capture-MS Homo sapiens
138 RPS6 6194
Co-fractionation Homo sapiens
139 ENY2 56943
Affinity Capture-MS Homo sapiens
140 RPLP0 6175
Co-fractionation Homo sapiens
141 BRD3 8019
Affinity Capture-MS Homo sapiens
142 MAGEB2 4113
Affinity Capture-MS Homo sapiens
143 TRIM31  
Affinity Capture-MS Homo sapiens
144 RPS15A 6210
Co-fractionation Homo sapiens
145 KLF12  
Proximity Label-MS Homo sapiens
146 CTNNBL1 56259
Affinity Capture-MS Homo sapiens
147 USP28 57646
Affinity Capture-MS Homo sapiens
148 CYLD  
Affinity Capture-MS Homo sapiens
149 SF3A3 10946
Affinity Capture-MS Homo sapiens
150 UBLCP1  
Affinity Capture-MS Homo sapiens
151 NARS 4677
Affinity Capture-MS Homo sapiens
152 PPP1R8 5511
Affinity Capture-MS Homo sapiens
153 RPL11 6135
Co-fractionation Homo sapiens
154 SLC4A7 9497
Affinity Capture-MS Homo sapiens
155 CNBP 7555
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
156 ANLN 54443
Affinity Capture-MS Homo sapiens
157 TPX2  
Affinity Capture-MS Homo sapiens
158 NUMA1 4926
Co-fractionation Homo sapiens
159 RPL32 6161
Co-fractionation Homo sapiens
160 TOMM34 10953
Affinity Capture-MS Homo sapiens
161 PAPSS1 9061
Affinity Capture-MS Homo sapiens
162 RPLP2 6181
Co-fractionation Homo sapiens
163 FANCD2  
Affinity Capture-MS Homo sapiens
164 SF1 7536
Affinity Capture-MS Homo sapiens
165 METTL14  
Affinity Capture-MS Homo sapiens
166 RPL23 9349
Co-fractionation Homo sapiens
167 RPS2 6187
Co-fractionation Homo sapiens
168 PTPN6 5777
Affinity Capture-MS Homo sapiens
169 ECT2 1894
Affinity Capture-MS Homo sapiens
170 DNAJC2 27000
Affinity Capture-MS Homo sapiens
171 LETM1 3954
Affinity Capture-MS Homo sapiens
172 RPL35 11224
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
173 CTNNB1 1499
Affinity Capture-MS Homo sapiens
174 NAA15 80155
Affinity Capture-MS Homo sapiens
175 VAMP3 9341
Affinity Capture-MS Homo sapiens
176 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
177 Rrbp1  
Affinity Capture-MS Mus musculus
178 DACH1  
Affinity Capture-MS Homo sapiens
179 RPL21 6144
Co-fractionation Homo sapiens
180 RPL3 6122
Co-fractionation Homo sapiens
181 DNAJC17  
Proximity Label-MS Homo sapiens
182 ETF1 2107
Affinity Capture-MS Homo sapiens
183 YY1 7528
Affinity Capture-MS Homo sapiens
184 MAVS 57506
Affinity Capture-MS Homo sapiens
185 FAM49B 51571
Affinity Capture-MS Homo sapiens
186 RPL7 6129
Co-fractionation Homo sapiens
187 RBM33  
Affinity Capture-MS Homo sapiens
188 PDS5B 23047
Affinity Capture-MS Homo sapiens
189 SF3A1 10291
Affinity Capture-MS Homo sapiens
190 RPS27 6232
Co-fractionation Homo sapiens
191 PSTPIP1 9051
Affinity Capture-MS Homo sapiens
192 NCAPH 23397
Affinity Capture-MS Homo sapiens
193 ZMPSTE24 10269
Affinity Capture-MS Homo sapiens
194 PCBP1 5093
Affinity Capture-MS Homo sapiens
195 FOS 2353
Affinity Capture-MS Homo sapiens
196 MYC  
Affinity Capture-MS Homo sapiens
197 RPA3 6119
Proximity Label-MS Homo sapiens
198 RPS13 6207
Co-fractionation Homo sapiens
199 NAA50 80218
Affinity Capture-MS Homo sapiens
200 KITLG  
Affinity Capture-MS Homo sapiens
201 EGFR 1956
Negative Genetic Homo sapiens
202 NDUFB8 4714
Affinity Capture-MS Homo sapiens
203 RPS14 6208
Co-fractionation Homo sapiens
204 RPL12 6136
Co-fractionation Homo sapiens
205 RPA4  
Proximity Label-MS Homo sapiens
206 RPL22 6146
Co-fractionation Homo sapiens
207 MYCN  
Affinity Capture-MS Homo sapiens
208 EIF2AK2 5610
Affinity Capture-MS Homo sapiens
209 HNF1B  
Affinity Capture-MS Homo sapiens
210 RPL18 6141
Co-fractionation Homo sapiens
211 DDRGK1 65992
Affinity Capture-MS Homo sapiens
212 COQ9  
Affinity Capture-MS Homo sapiens
213 LRRC40 55631
Affinity Capture-MS Homo sapiens
214 CPSF3L 54973
Affinity Capture-MS Homo sapiens
215 BMP4 652
Affinity Capture-MS Homo sapiens
216 ZC3H11A  
Affinity Capture-MS Homo sapiens
217 RPL15 6138
Co-fractionation Homo sapiens
218 SCCPDH 51097
Affinity Capture-MS Homo sapiens
219 RPS16 6217
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
220 DDX46 9879
Affinity Capture-MS Homo sapiens
221 AK4 205
Affinity Capture-MS Homo sapiens
222 RPL13 6137
Co-fractionation Homo sapiens
223 RPL37 6167
Co-fractionation Homo sapiens
224 GLS 2744
Affinity Capture-MS Homo sapiens
225 KIF2A 3796
Affinity Capture-MS Homo sapiens
226 ARRB2 409
Affinity Capture-MS Homo sapiens
227 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
228 IDH3G 3421
Affinity Capture-MS Homo sapiens
229 LZIC 84328
Affinity Capture-MS Homo sapiens
230 TERF2  
Affinity Capture-MS Homo sapiens
231 RPS25 6230
Co-fractionation Homo sapiens
232 PARP1 142
Proximity Label-MS Homo sapiens
233 BKRF1  
Affinity Capture-MS
234 HDGF 3068
Affinity Capture-MS Homo sapiens
235 MCTS1 28985
Affinity Capture-MS Homo sapiens
236 RRS1 23212
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
237 RPL6 6128
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
238 CIT 11113
Affinity Capture-MS Homo sapiens
239 FOLR1 2348
Affinity Capture-MS Homo sapiens
240 PIN1 5300
Affinity Capture-MS Homo sapiens
241 GINS1  
Affinity Capture-MS Homo sapiens
242 DUSP3 1845
Affinity Capture-MS Homo sapiens
243 USP36  
Affinity Capture-MS Homo sapiens
244 ARF5 381
Affinity Capture-MS Homo sapiens
245 UBA52 7311
Co-fractionation Homo sapiens
246 RPS12 6206
Co-fractionation Homo sapiens
247 HMGN5 79366
Affinity Capture-MS Homo sapiens
248 LASP1 3927
Affinity Capture-MS Homo sapiens
249 RPS4X 6191
Co-fractionation Homo sapiens
250 RPS15 6209
Co-fractionation Homo sapiens
251 NSDHL 50814
Affinity Capture-MS Homo sapiens
252 SRP72 6731
Affinity Capture-MS Homo sapiens
253 Cpsf6  
Two-hybrid Mus musculus
254 CAPRIN1 4076
Affinity Capture-MS Homo sapiens
255 RNF20 56254
Affinity Capture-MS Homo sapiens
256 MTHFD1 4522
Co-fractionation Homo sapiens
257 DDX58 23586
Affinity Capture-RNA Homo sapiens
258 SYAP1 94056
Affinity Capture-MS Homo sapiens
259 MAP2K1 5604
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
260 RPL34 6164
Co-fractionation Homo sapiens
261 S100A8 6279
Affinity Capture-MS Homo sapiens
262 RAVER1 125950
Affinity Capture-MS Homo sapiens
263 PDZD8 118987
Affinity Capture-MS Homo sapiens
264 UFL1 23376
Affinity Capture-MS Homo sapiens
265 RPL10A 4736
Co-fractionation Homo sapiens
266 SETD8  
Affinity Capture-MS Homo sapiens
267 PPP1R12A 4659
Affinity Capture-MS Homo sapiens
268 NCL 4691
Affinity Capture-MS Homo sapiens
269 WIBG 84305
Affinity Capture-MS Homo sapiens
270 TRIP4 9325
Affinity Capture-MS Homo sapiens
271 NDRG1 10397
Affinity Capture-MS Homo sapiens
272 RPL7A 6130
Co-fractionation Homo sapiens
273 RPS8 6202
Co-fractionation Homo sapiens
274 RPL8 6132
Co-fractionation Homo sapiens
275 PHF3  
Affinity Capture-MS Homo sapiens
276 RPRD1B 58490
Affinity Capture-MS Homo sapiens
277 RPS27L 51065
Co-fractionation Homo sapiens
278 XPNPEP1 7511
Affinity Capture-MS Homo sapiens
279 RPL23A 6147
Co-fractionation Homo sapiens
280 KRAS 3845
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
281 UHRF1 29128
Affinity Capture-MS Homo sapiens
282 C9orf72  
Affinity Capture-MS Homo sapiens
283 RPL36AL 6166
Co-fractionation Homo sapiens
284 RBM34  
Affinity Capture-MS Homo sapiens
285 SCML2  
Affinity Capture-MS Homo sapiens
286 TTLL12 23170
Affinity Capture-MS Homo sapiens
287 WDHD1  
Affinity Capture-MS Homo sapiens
288 RPL17 6139
Co-fractionation Homo sapiens
289 ASB2  
Affinity Capture-MS Homo sapiens
290 C12orf57 113246
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which RPL35A is involved
PathwayEvidenceSource
Axon guidance IEA Reactome
Cap-dependent Translation Initiation TAS Reactome
Cellular response to starvation IEA Reactome
Cellular responses to stimuli IEA Reactome
Cellular responses to stress IEA Reactome
Developmental Biology IEA Reactome
Disease TAS Reactome
Eukaryotic Translation Elongation IEA Reactome
Eukaryotic Translation Initiation TAS Reactome
Eukaryotic Translation Termination IEA Reactome
Formation of a pool of free 40S subunits TAS Reactome
GTP hydrolysis and joining of the 60S ribosomal subunit TAS Reactome
Infectious disease TAS Reactome
Influenza Infection TAS Reactome
Influenza Viral RNA Transcription and Replication TAS Reactome
L13a-mediated translational silencing of Ceruloplasmin expression TAS Reactome
Major pathway of rRNA processing in the nucleolus and cytosol TAS Reactome
Metabolism IEA Reactome
Metabolism of amino acids and derivatives IEA Reactome
Metabolism of proteins TAS Reactome
Metabolism of proteins IEA Reactome
Metabolism of RNA TAS Reactome
Nervous system development IEA Reactome
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) TAS Reactome
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) TAS Reactome
Nonsense-Mediated Decay (NMD) TAS Reactome
Peptide chain elongation IEA Reactome
Regulation of expression of SLITs and ROBOs IEA Reactome
Response of EIF2AK4 (GCN2) to amino acid deficiency IEA Reactome
rRNA processing TAS Reactome
rRNA processing in the nucleus and cytosol TAS Reactome
Selenoamino acid metabolism IEA Reactome
Selenocysteine synthesis IEA Reactome
Signaling by ROBO receptors IEA Reactome
SRP-dependent cotranslational protein targeting to membrane IEA Reactome
SRP-dependent cotranslational protein targeting to membrane TAS Reactome
Translation TAS Reactome
Translation IEA Reactome
Viral Infection Pathways TAS Reactome
Viral mRNA Translation TAS Reactome





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