Gene description for SRRT
Gene name serrate, RNA effector molecule
Gene symbol SRRT
Other names/aliases ARS2
ASR2
serrate
Species Homo sapiens
 Database cross references - SRRT
ExoCarta ExoCarta_51593
Vesiclepedia VP_51593
Entrez Gene 51593
HGNC 24101
MIM 614469
UniProt Q9BXP5  
 SRRT identified in sEVs derived from the following tissue/cell type
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for SRRT
Molecular Function
    DNA binding GO:0003677 ISS
    RNA binding GO:0003723 HDA
    protein binding GO:0005515 IPI
    protein-macromolecule adaptor activity GO:0030674 IDA
    mRNA cap binding complex binding GO:0140262 IDA
Biological Process
    regulation of DNA-templated transcription GO:0006355 ISS
    mRNA processing GO:0006397 IEA
    primary miRNA processing GO:0031053 IBA
    primary miRNA processing GO:0031053 IMP
    response to arsenic-containing substance GO:0046685 NAS
    positive regulation of neurogenesis GO:0050769 IEA
    neuronal stem cell population maintenance GO:0097150 ISS
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 ISS
    nucleoplasm GO:0005654 TAS
    cytoplasm GO:0005737 ISS
    nuclear body GO:0016604 IBA
    protein-containing complex GO:0032991 IDA
    ribonucleoprotein complex GO:1990904 IDA
 Experiment description of studies that identified SRRT in sEVs
1
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
2
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
3
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
4
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
5
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
8
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
11
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
12
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
18
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
20
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
24
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
25
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
28
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
29
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
33
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SRRT
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 SNRPA 6626
Affinity Capture-MS Homo sapiens
3 RIT1 6016
Negative Genetic Homo sapiens
4 CPSF6 11052
Affinity Capture-MS Homo sapiens
5 LUZP4  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
6 Tmed2 56334
Affinity Capture-MS Mus musculus
7 NCBP1 4686
Affinity Capture-MS Homo sapiens
8 SERPINB4 6318
Affinity Capture-MS Homo sapiens
9 LGR4 55366
Affinity Capture-MS Homo sapiens
10 TSSK2  
Co-fractionation Homo sapiens
11 FBXO7 25793
Affinity Capture-MS Homo sapiens
12 OGFOD1  
Co-fractionation Homo sapiens
13 ANLN 54443
Affinity Capture-MS Homo sapiens
14 IVL 3713
Affinity Capture-MS Homo sapiens
15 ADH7  
Affinity Capture-MS Homo sapiens
16 TARDBP 23435
Affinity Capture-MS Homo sapiens
17 SP1  
Affinity Capture-MS Homo sapiens
18 MCM7 4176
Co-fractionation Homo sapiens
19 SERPINB13 5275
Affinity Capture-MS Homo sapiens
20 LIMS1 3987
Affinity Capture-MS Homo sapiens
21 FAM213A 84293
Affinity Capture-MS Homo sapiens
22 MAGEA1  
Affinity Capture-MS Homo sapiens
23 DHRS1 115817
Affinity Capture-MS Homo sapiens
24 TOP1 7150
Affinity Capture-MS Homo sapiens
25 CSNK2A1 1457
Biochemical Activity Homo sapiens
26 IL1RN 3557
Affinity Capture-MS Homo sapiens
27 KPNA2 3838
Affinity Capture-MS Homo sapiens
28 NEFM 4741
Cross-Linking-MS (XL-MS) Homo sapiens
29 SNRPF 6636
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
30 SNRPD2 6633
Affinity Capture-MS Homo sapiens
31 APP 351
Reconstituted Complex Homo sapiens
32 CENPA  
Co-purification Homo sapiens
33 S100A14 57402
Affinity Capture-MS Homo sapiens
34 HNRNPUL2 221092
Affinity Capture-MS Homo sapiens
35 CPSF2 53981
Affinity Capture-MS Homo sapiens
36 MAOB  
Affinity Capture-MS Homo sapiens
37 RNPS1 10921
Affinity Capture-MS Homo sapiens
38 SPRR3 6707
Affinity Capture-MS Homo sapiens
39 ZG16B 124220
Affinity Capture-MS Homo sapiens
40 Cep85l  
Affinity Capture-MS Mus musculus
41 GTF2F2 2963
Co-fractionation Homo sapiens
42 HSPA5 3309
Co-fractionation Homo sapiens
43 PPP6C 5537
Co-fractionation Homo sapiens
44 C3 718
Affinity Capture-MS Homo sapiens
45 SF3B1 23451
Affinity Capture-MS Homo sapiens
46 FAM129B 64855
Affinity Capture-MS Homo sapiens
47 PRC1 9055
Affinity Capture-MS Homo sapiens
48 DSC2 1824
Affinity Capture-MS Homo sapiens
49 C2orf54  
Affinity Capture-MS Homo sapiens
50 STAT3 6774
Two-hybrid Homo sapiens
51 SNRPC 6631
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
52 CLIP1 6249
Affinity Capture-MS Homo sapiens
53 OBSL1 23363
Affinity Capture-MS Homo sapiens
54 TINF2  
Affinity Capture-MS Homo sapiens
55 SOST  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
56 MAGED2 10916
Co-fractionation Homo sapiens
57 SERPINB1 1992
Affinity Capture-MS Homo sapiens
58 C17orf85  
Proximity Label-MS Homo sapiens
59 SF3B3 23450
Co-fractionation Homo sapiens
60 CES1  
Affinity Capture-MS Homo sapiens
61 ACLY 47
Co-fractionation Homo sapiens
62 DSG3 1830
Affinity Capture-MS Homo sapiens
63 EED  
Affinity Capture-MS Homo sapiens
64 ENDOU  
Affinity Capture-MS Homo sapiens
65 MECP2 4204
Affinity Capture-MS Homo sapiens
66 PPP6R3 55291
Co-fractionation Homo sapiens
67 MYCN  
Affinity Capture-MS Homo sapiens
68 RBM42  
Affinity Capture-MS Homo sapiens
69 CHD3 1107
Two-hybrid Homo sapiens
70 NARS 4677
Affinity Capture-MS Homo sapiens
71 RBM14 10432
Affinity Capture-MS Homo sapiens
72 Tmed10 68581
Affinity Capture-MS Mus musculus
73 HSPA8 3312
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
74 LIN28A  
Affinity Capture-MS Homo sapiens
75 PSME3 10197
Co-fractionation Homo sapiens
76 TGM3 7053
Affinity Capture-MS Homo sapiens
77 CST2  
Affinity Capture-MS Homo sapiens
78 CLK2 1196
Affinity Capture-MS Homo sapiens
79 ALDH1A3 220
Affinity Capture-MS Homo sapiens
80 SF3A2 8175
Affinity Capture-MS Homo sapiens
81 DLD 1738
Affinity Capture-MS Homo sapiens
82 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
83 DDX21 9188
Affinity Capture-MS Homo sapiens
84 IGHA2 3494
Affinity Capture-MS Homo sapiens
85 SCEL 8796
Affinity Capture-MS Homo sapiens
86 SMARCA5 8467
Co-fractionation Homo sapiens
87 CALML3 810
Affinity Capture-MS Homo sapiens
88 PARK2  
Affinity Capture-MS Homo sapiens
89 PHAX  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
90 ACADVL 37
Affinity Capture-MS Homo sapiens
91 AKR1C3 8644
Affinity Capture-MS Homo sapiens
92 TRA2A 29896
Affinity Capture-MS Homo sapiens
93 RBM7  
Affinity Capture-MS Homo sapiens
94 MGLL 11343
Affinity Capture-MS Homo sapiens
95 SRSF6 6431
Affinity Capture-MS Homo sapiens
96 FAM162A 26355
Co-fractionation Homo sapiens
97 AKR7L 246181
Affinity Capture-MS Homo sapiens
98 S100A16 140576
Affinity Capture-MS Homo sapiens
99 MKRN2 23609
Affinity Capture-RNA Homo sapiens
100 GIT1 28964
Two-hybrid Homo sapiens
101 Rab3gap1  
Affinity Capture-MS Mus musculus
102 WDYHV1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
103 NTRK1 4914
Affinity Capture-MS Homo sapiens
104 SAR1B 51128
Affinity Capture-MS Homo sapiens
105 LUC7L2 51631
Affinity Capture-MS Homo sapiens
106 TACSTD2 4070
Affinity Capture-MS Homo sapiens
107 ALDH3A1 218
Affinity Capture-MS Homo sapiens
108 DHX9 1660
Co-fractionation Homo sapiens
109 HECTD1 25831
Affinity Capture-MS Homo sapiens
110 VAV2 7410
Two-hybrid Homo sapiens
111 ZFC3H1 196441
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
112 MBD3 53615
Co-fractionation Homo sapiens
113 DDX39B 7919
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
114 H2AFY 9555
Affinity Capture-MS Homo sapiens
115 ANXA8 653145
Affinity Capture-MS Homo sapiens
116 MCM2 4171
Co-fractionation Homo sapiens
117 CRNN 49860
Affinity Capture-MS Homo sapiens
118 Ncbp2  
Affinity Capture-MS Mus musculus
119 RPA3 6119
Proximity Label-MS Homo sapiens
120 SNRPB2 6629
Affinity Capture-MS Homo sapiens
121 SQRDL 58472
Affinity Capture-MS Homo sapiens
122 COPS8 10920
Co-fractionation Homo sapiens
123 ELAVL2 1993
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
124 SBDS 51119
Affinity Capture-MS Homo sapiens
125 RNF40 9810
Affinity Capture-MS Homo sapiens
126 PSMA3 5684
Affinity Capture-MS Homo sapiens
127 SERPINB3 6317
Affinity Capture-MS Homo sapiens
128 CCNA2 890
Affinity Capture-MS Homo sapiens
129 PRPF4B 8899
Affinity Capture-MS Homo sapiens
130 FANCD2  
Affinity Capture-MS Homo sapiens
131 MX1 4599
Affinity Capture-MS Homo sapiens
132 MUC7 4589
Affinity Capture-MS Homo sapiens
133 CLK3  
Affinity Capture-MS Homo sapiens
134 XPO1 7514
Affinity Capture-MS Homo sapiens
135 NCBP2 22916
Affinity Capture-MS Homo sapiens
136 ECT2 1894
Affinity Capture-MS Homo sapiens
137 Dennd6a  
Affinity Capture-MS Mus musculus
138 HMGCS1 3157
Affinity Capture-MS Homo sapiens
139 SNRPB 6628
Affinity Capture-MS Homo sapiens
140 CRYAB 1410
Affinity Capture-MS Homo sapiens
141 RPL35A 6165
Affinity Capture-MS Homo sapiens
142 RAB25 57111
Affinity Capture-MS Homo sapiens
143 CD274 29126
Affinity Capture-MS Homo sapiens
144 HYPK 25764
Affinity Capture-MS Homo sapiens
145 CUL3 8452
Affinity Capture-MS Homo sapiens
146 CD9 928
Affinity Capture-MS Homo sapiens
147 EGFR 1956
Negative Genetic Homo sapiens
148 OSGEP 55644
Affinity Capture-MS Homo sapiens
149 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
150 FUS 2521
Affinity Capture-MS Homo sapiens
151 GBP6 163351
Affinity Capture-MS Homo sapiens
152 POLR2A 5430
Co-fractionation Homo sapiens
153 SERPINB5 5268
Affinity Capture-MS Homo sapiens
154 PKP3 11187
Affinity Capture-MS Homo sapiens
155 A2ML1 144568
Affinity Capture-MS Homo sapiens
156 SF3A1 10291
Affinity Capture-MS Homo sapiens
157 AMY1C 278
Affinity Capture-MS Homo sapiens
158 ASB12  
Affinity Capture-MS Homo sapiens
159 GEMIN4 50628
Two-hybrid Homo sapiens
160 RGS13  
Affinity Capture-MS Homo sapiens
161 CST4 1472
Affinity Capture-MS Homo sapiens
162 MCM4 4173
Co-fractionation Homo sapiens
163 PSPC1 55269
Affinity Capture-MS Homo sapiens
164 Uso1 56041
Affinity Capture-MS Mus musculus
165 ZC3H18  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
166 APEH 327
Co-fractionation Homo sapiens
167 PABPC5 140886
Affinity Capture-MS Homo sapiens
168 Sesn2  
Affinity Capture-MS Mus musculus
169 IP6K3  
Affinity Capture-MS Homo sapiens
170 SAMD9 54809
Affinity Capture-MS Homo sapiens
171 EVPL 2125
Affinity Capture-MS Homo sapiens
172 ANXA1 301
Affinity Capture-MS Homo sapiens
173 IGHG1 3500
Affinity Capture-MS Homo sapiens
174 PCGF1 84759
Affinity Capture-MS Homo sapiens
175 PLEKHG1  
Affinity Capture-MS Homo sapiens
176 Jup 16480
Affinity Capture-MS Mus musculus
177 BMI1  
Affinity Capture-MS Homo sapiens
178 BPIFA2 140683
Affinity Capture-MS Homo sapiens
179 RBBP5 5929
Co-fractionation Homo sapiens
180 ARHGEF40 55701
Affinity Capture-MS Homo sapiens
181 EPS8L2 64787
Affinity Capture-MS Homo sapiens
182 RBM11  
Affinity Capture-MS Homo sapiens
183 TGM1 7051
Affinity Capture-MS Homo sapiens
184 PAIP1 10605
Affinity Capture-MS Homo sapiens
185 IMMT 10989
Two-hybrid Homo sapiens
186 JMJD7-PLA2G4B  
Affinity Capture-MS Homo sapiens
187 SNCA 6622
Affinity Capture-MS Homo sapiens
188 MRPL42  
Affinity Capture-MS Homo sapiens
189 LINC00624  
Protein-RNA Homo sapiens
190 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
191 PRKCSH 5589
Co-fractionation Homo sapiens
192 Tubg1 103733
Affinity Capture-MS Mus musculus
193 SIRT6  
Affinity Capture-MS Homo sapiens
194 KIF14 9928
Affinity Capture-MS Homo sapiens
195 BKRF1  
Affinity Capture-MS
196 Sod1 20655
Affinity Capture-MS Mus musculus
197 WDR77 79084
Affinity Capture-MS Homo sapiens
198 JUP 3728
Affinity Capture-MS Homo sapiens
199 Osgep  
Affinity Capture-MS Mus musculus
200 CLCA4 22802
Affinity Capture-MS Homo sapiens
201 PDIA4 9601
Co-fractionation Homo sapiens
202 VIM 7431
Two-hybrid Homo sapiens
203 CRABP2 1382
Affinity Capture-MS Homo sapiens
204 AKR1C2  
Affinity Capture-MS Homo sapiens
205 SAP18 10284
Co-fractionation Homo sapiens
206 PTGR1 22949
Affinity Capture-MS Homo sapiens
207 PDHA1 5160
Affinity Capture-MS Homo sapiens
208 EPS8L1 54869
Affinity Capture-MS Homo sapiens
209 HNRNPM 4670
Co-fractionation Homo sapiens
210 RBM39 9584
Affinity Capture-MS Homo sapiens
211 PRMT1 3276
Affinity Capture-MS Homo sapiens
212 IGHG2 3501
Affinity Capture-MS Homo sapiens
213 CHD4 1108
Affinity Capture-MS Homo sapiens
214 HSP90AA1 3320
Cross-Linking-MS (XL-MS) Homo sapiens
215 EIF4A3 9775
Co-fractionation Homo sapiens
216 S100A9 6280
Co-fractionation Homo sapiens
217 PPL 5493
Affinity Capture-MS Homo sapiens
218 PKP1 5317
Affinity Capture-MS Homo sapiens
219 HNRNPK 3190
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
220 HTR6  
Two-hybrid Homo sapiens
221 SNRNP40 9410
Affinity Capture-MS Homo sapiens
222 WDHD1  
Co-fractionation Homo sapiens
223 SNIP1  
Affinity Capture-MS Homo sapiens
224 ALYREF 10189
Affinity Capture-MS Homo sapiens
225 HNRNPL 3191
Affinity Capture-MS Homo sapiens
226 TTC21A  
Cross-Linking-MS (XL-MS) Homo sapiens
227 AKR1B10 57016
Affinity Capture-MS Homo sapiens
228 EEF1D 1936
Co-fractionation Homo sapiens
229 NDRG1 10397
Affinity Capture-MS Homo sapiens
230 SRSF7 6432
Affinity Capture-MS Homo sapiens
231 ZNF185 7739
Affinity Capture-MS Homo sapiens
232 TRIM28 10155
Co-fractionation Homo sapiens
233 TMPRSS11D 9407
Affinity Capture-MS Homo sapiens
234 SERPINB2 5055
Affinity Capture-MS Homo sapiens
235 CAPG 822
Affinity Capture-MS Homo sapiens
236 SERBP1 26135
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
237 CUL7 9820
Affinity Capture-MS Homo sapiens
238 ECM1 1893
Affinity Capture-MS Homo sapiens
239 SYN1  
Co-fractionation Homo sapiens
240 SRP9 6726
Affinity Capture-MS Homo sapiens
241 MYC  
Affinity Capture-MS Homo sapiens
242 TRIM29 23650
Affinity Capture-MS Homo sapiens
243 SSRP1 6749
Affinity Capture-MS Homo sapiens
244 MEN1 4221
Affinity Capture-MS Homo sapiens
245 SP7  
Proximity Label-MS Homo sapiens
246 LUC7L 55692
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
247 NOTCH1 4851
Affinity Capture-MS Homo sapiens
248 SULT2B1 6820
Affinity Capture-MS Homo sapiens
249 EP300 2033
Affinity Capture-MS Homo sapiens
250 BAIAP2 10458
Affinity Capture-MS Homo sapiens
251 GTF2E2  
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here