Gene description for DCTN1
Gene name dynactin 1
Gene symbol DCTN1
Other names/aliases DAP-150
DP-150
P135
Species Homo sapiens
 Database cross references - DCTN1
ExoCarta ExoCarta_1639
Vesiclepedia VP_1639
Entrez Gene 1639
HGNC 2711
MIM 601143
UniProt Q14203  
 DCTN1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 36706192    
Embryonic kidney cells 36706192    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells Unpublished / Not applicable
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for DCTN1
Molecular Function
    protein binding GO:0005515 IPI
    microtubule binding GO:0008017 IDA
    microtubule binding GO:0008017 IMP
    tubulin binding GO:0015631 IDA
    protein kinase binding GO:0019901 IPI
    tau protein binding GO:0048156 NAS
Biological Process
    establishment of mitotic spindle orientation GO:0000132 IBA
    establishment of mitotic spindle orientation GO:0000132 IMP
    mitotic cell cycle GO:0000278 NAS
    nuclear migration GO:0007097 IBA
    nervous system development GO:0007399 NAS
    neuromuscular junction development GO:0007528 IMP
    centriole-centriole cohesion GO:0010457 IMP
    ventral spinal cord development GO:0021517 IMP
    positive regulation of microtubule polymerization GO:0031116 IDA
    positive regulation of microtubule polymerization GO:0031116 IMP
    melanosome transport GO:0032402 IEA
    microtubule anchoring at centrosome GO:0034454 IMP
    retrograde transport, endosome to Golgi GO:0042147 IMP
    neuromuscular process GO:0050905 IMP
    nuclear membrane disassembly GO:0051081 IMP
    cell division GO:0051301 IEA
    regulation of mitotic spindle organization GO:0060236 IMP
    motor behavior GO:0061744 IMP
    neuron cellular homeostasis GO:0070050 IMP
    positive regulation of microtubule nucleation GO:0090063 IDA
    axonal transport GO:0098930 IMP
    maintenance of synapse structure GO:0099558 TAS
    positive regulation of neuromuscular junction development GO:1904398 IMP
    non-motile cilium assembly GO:1905515 IMP
    neuron projection maintenance GO:1990535 IMP
Subcellular Localization
    kinetochore GO:0000776 IBA
    kinetochore GO:0000776 IDA
    spindle pole GO:0000922 IBA
    spindle pole GO:0000922 IDA
    nuclear envelope GO:0005635 IDA
    cytoplasm GO:0005737 IDA
    centrosome GO:0005813 IDA
    centriole GO:0005814 IDA
    spindle GO:0005819 IDA
    cytosol GO:0005829 TAS
    microtubule GO:0005874 IDA
    microtubule associated complex GO:0005875 IBA
    microtubule associated complex GO:0005875 IMP
    cell cortex GO:0005938 IDA
    cell cortex GO:0005938 IDA
    microtubule cytoskeleton GO:0015630 IDA
    membrane GO:0016020 HDA
    dynein complex GO:0030286 IEA
    axon GO:0030424 IBA
    retromer complex GO:0030904 IDA
    cell leading edge GO:0031252 IEA
    microtubule plus-end GO:0035371 IDA
    ciliary basal body GO:0036064 IEA
    neuron projection GO:0043005 IDA
    neuronal cell body GO:0043025 IDA
    intercellular bridge GO:0045171 IDA
    mitotic spindle GO:0072686 IDA
    cell cortex region GO:0099738 IDA
    centriolar subdistal appendage GO:0120103 IDA
 Experiment description of studies that identified DCTN1 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
11
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
14
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
15
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
16
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
19
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
20
Experiment ID 1275
MISEV standards
Biophysical techniques
✔
CD9|TSG101|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 1280
MISEV standards
Biophysical techniques
✔
TSG101|CD9|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T - Fraction 5
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density 1.151 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
24
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
25
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
26
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
29
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
30
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
33
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
34
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
37
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
38
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
39
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
40
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
41
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
42
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for DCTN1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 CCAR1 55749
Co-fractionation Homo sapiens
3 MCM7 4176
Co-fractionation Homo sapiens
4 PFDN1 5201
Two-hybrid Homo sapiens
5 NUF2  
Proximity Label-MS Homo sapiens
6 ARHGEF2 9181
Proximity Label-MS Homo sapiens
7 HOOK1  
Proximity Label-MS Homo sapiens
8 GEN1  
Proximity Label-MS Homo sapiens
9 CYFIP1 23191
Co-fractionation Homo sapiens
10 LGR4 55366
Affinity Capture-MS Homo sapiens
11 RBL2 5934
Two-hybrid Homo sapiens
12 KIAA1107  
Proximity Label-MS Homo sapiens
13 Dctn1 13191
Affinity Capture-MS Mus musculus
Affinity Capture-MS Mus musculus
14 DCTN6 10671
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 SMURF1 57154
Affinity Capture-MS Homo sapiens
16 IPO7 10527
Proximity Label-MS Homo sapiens
17 MAP1S 55201
Proximity Label-MS Homo sapiens
18 RPS19BP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 DYNC1I2 1781
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
20 TRIM26 7726
Proximity Label-MS Homo sapiens
21 YWHAE 7531
Affinity Capture-MS Homo sapiens
22 MCM3 4172
Co-fractionation Homo sapiens
23 ACTC1 70
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
24 SNX2 6643
Co-fractionation Homo sapiens
25 HSPA12B 116835
Proximity Label-MS Homo sapiens
26 DYNC1I1  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
27 MAP4 4134
Proximity Label-MS Homo sapiens
28 KIF20A 10112
Affinity Capture-MS Homo sapiens
29 NAV1 89796
Proximity Label-MS Homo sapiens
30 MCCC1 56922
Co-fractionation Homo sapiens
31 RIC8A 60626
Affinity Capture-MS Homo sapiens
32 DHX57 90957
Proximity Label-MS Homo sapiens
33 CAMSAP2  
Proximity Label-MS Homo sapiens
34 KIF7 374654
Proximity Label-MS Homo sapiens
35 CCDC124 115098
Proximity Label-MS Homo sapiens
36 KIF1B 23095
Proximity Label-MS Homo sapiens
37 ANKRD28 23243
Proximity Label-MS Homo sapiens
38 AGAP3 116988
Affinity Capture-MS Homo sapiens
39 DCTN3 11258
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 HMMR  
Proximity Label-MS Homo sapiens
41 APEX1 328
Affinity Capture-RNA Homo sapiens
42 KIAA1429 25962
Affinity Capture-MS Homo sapiens
43 FBXW4 6468
Affinity Capture-MS Homo sapiens
44 CAPZB 832
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 DUSP12 11266
Affinity Capture-MS Homo sapiens
46 MARK2 2011
Proximity Label-MS Homo sapiens
47 SNX3 8724
Co-fractionation Homo sapiens
48 JAKMIP1 152789
Proximity Label-MS Homo sapiens
49 GKAP1  
Proximity Label-MS Homo sapiens
50 DYNC1LI2 1783
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
51 PSRC1  
Proximity Label-MS Homo sapiens
52 CFAP97  
Proximity Label-MS Homo sapiens
53 SKA3  
Proximity Label-MS Homo sapiens
54 DCTN4 51164
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 CAMSAP1 157922
Proximity Label-MS Homo sapiens
56 RFXANK  
Affinity Capture-MS Homo sapiens
57 ESPL1  
Proximity Label-MS Homo sapiens
58 UPF3B 65109
Proximity Label-MS Homo sapiens
59 TTN 7273
Proximity Label-MS Homo sapiens
60 DIAPH3 81624
Proximity Label-MS Homo sapiens
61 FBXW7  
Affinity Capture-MS Homo sapiens
62 PRC1 9055
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
63 TXNL1 9352
Proximity Label-MS Homo sapiens
64 CLIP1 6249
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
65 ACTR1A 10121
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 ZNF512B  
Two-hybrid Homo sapiens
67 SPECC1L 23384
Proximity Label-MS Homo sapiens
68 PSMB6 5694
Co-fractionation Homo sapiens
69 MAP7 9053
Proximity Label-MS Homo sapiens
70 SMC2 10592
Co-fractionation Homo sapiens
71 Cep76  
Affinity Capture-MS Mus musculus
72 Cenpe  
Affinity Capture-MS Mus musculus
73 HAUS6  
Proximity Label-MS Homo sapiens
74 TUBB3 10381
Proximity Label-MS Homo sapiens
75 Kctd5  
Affinity Capture-MS Mus musculus
76 DYNLL1 8655
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
77 DCLK1 9201
Proximity Label-MS Homo sapiens
78 Dctn4  
Affinity Capture-MS Mus musculus
79 CDC27 996
Proximity Label-MS Homo sapiens
80 KIF2C 11004
Proximity Label-MS Homo sapiens
81 YWHAB 7529
Affinity Capture-MS Homo sapiens
82 HAP1  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
83 PPP6R1 22870
Proximity Label-MS Homo sapiens
84 NAP1L4 4676
Proximity Label-MS Homo sapiens
85 GTSE1 51512
Proximity Label-MS Homo sapiens
86 Dctn5  
Affinity Capture-MS Mus musculus
87 ZNF622 90441
Proximity Label-MS Homo sapiens
88 HUWE1 10075
Affinity Capture-MS Homo sapiens
89 AKTIP  
Affinity Capture-MS Homo sapiens
90 KNSTRN  
Proximity Label-MS Homo sapiens
91 CEP131 22994
Proximity Label-MS Homo sapiens
92 ADSS 159
Cross-Linking-MS (XL-MS) Homo sapiens
93 DLGAP5  
Proximity Label-MS Homo sapiens
94 MTA2 9219
Co-fractionation Homo sapiens
95 DYNLT1 6993
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
96 KIF14 9928
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
97 CLASP2 23122
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
98 MAP2 4133
Proximity Label-MS Homo sapiens
99 FBXL5  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
100 PAK4 10298
Proximity Label-MS Homo sapiens
101 C1orf106  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
102 AURKA 6790
Affinity Capture-MS Homo sapiens
103 CAMK2A 815
Affinity Capture-MS Homo sapiens
104 MAPK8IP3  
Affinity Capture-MS Homo sapiens
105 PPP1CA 5499
Two-hybrid Homo sapiens
106 DCLK2 166614
Proximity Label-MS Homo sapiens
107 CC2D1B 200014
Co-fractionation Homo sapiens
108 IPO8 10526
Proximity Label-MS Homo sapiens
109 ENSA 2029
Proximity Label-MS Homo sapiens
110 EML4 27436
Proximity Label-MS Homo sapiens
111 CEP55 55165
Proximity Label-MS Homo sapiens
112 CAPZA1 829
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
113 CEP41  
Proximity Label-MS Homo sapiens
114 LUZP1 7798
Proximity Label-MS Homo sapiens
115 DCTN5 84516
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
116 CCDC88C 440193
Affinity Capture-Western Homo sapiens
117 PSMD11 5717
Co-fractionation Homo sapiens
118 MAPRE1 22919
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
119 PSMD14 10213
Affinity Capture-MS Homo sapiens
120 PDLIM3 27295
Proximity Label-MS Homo sapiens
121 OFD1 8481
Proximity Label-MS Homo sapiens
122 DTNBP1  
Two-hybrid Homo sapiens
123 CCNB1 891
Proximity Label-MS Homo sapiens
124 MAPT  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Co-purification Homo sapiens
Proximity Label-MS Homo sapiens
125 RPL18A 6142
Cross-Linking-MS (XL-MS) Homo sapiens
126 MED14  
Two-hybrid Homo sapiens
127 LRRFIP1 9208
Cross-Linking-MS (XL-MS) Homo sapiens
128 CEP170 9859
Proximity Label-MS Homo sapiens
129 HAUS8  
Proximity Label-MS Homo sapiens
130 Actr1b 226977
Affinity Capture-MS Mus musculus
131 RNF168  
Co-fractionation Homo sapiens
132 NTRK1 4914
Affinity Capture-MS Homo sapiens
133 CENPE 1062
Proximity Label-MS Homo sapiens
134 YWHAH 7533
Affinity Capture-MS Homo sapiens
135 ARHGAP11A  
Affinity Capture-MS Homo sapiens
136 HSPA1A 3303
Cross-Linking-MS (XL-MS) Homo sapiens
137 PLK1 5347
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
138 DCTN1 1639
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
139 PEX14 5195
Co-purification Homo sapiens
140 KIF11 3832
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
141 HIST1H1C 3006
Cross-Linking-MS (XL-MS) Homo sapiens
142 SPAG5 10615
Proximity Label-MS Homo sapiens
143 ACTB 60
Affinity Capture-MS Homo sapiens
144 SLAIN1 122060
Proximity Label-MS Homo sapiens
145 BBS4 585
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
146 Coro1c 23790
Affinity Capture-MS Mus musculus
147 DYNLL2 140735
Affinity Capture-MS Homo sapiens
148 KIAA1217 56243
Proximity Label-MS Homo sapiens
149 NINL  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
150 APC  
Proximity Label-MS Homo sapiens
151 ACTR10 55860
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
152 ACTG1 71
Affinity Capture-MS Homo sapiens
153 CYLD  
Affinity Capture-MS Homo sapiens
154 SF3A3 10946
Co-fractionation Homo sapiens
155 BZW1 9689
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
156 IPO9 55705
Proximity Label-MS Homo sapiens
157 MAP1A 4130
Proximity Label-MS Homo sapiens
158 POLR2B 5431
Co-fractionation Homo sapiens
159 DCDC5  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
160 NCKAP5L  
Proximity Label-MS Homo sapiens
161 DST 667
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
162 DISC1 27185
Two-hybrid Homo sapiens
163 HNRNPD 3184
Cross-Linking-MS (XL-MS) Homo sapiens
164 PRKCSH 5589
Co-fractionation Homo sapiens
165 RAB6A 5870
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
166 SLAIN2  
Proximity Label-MS Homo sapiens
167 SEPT14  
Affinity Capture-MS Homo sapiens
168 DNAJC21  
Proximity Label-MS Homo sapiens
169 SYNJ2 8871
Proximity Label-MS Homo sapiens
170 Bicd2  
Affinity Capture-Western Mus musculus
171 NASP 4678
Co-fractionation Homo sapiens
172 SOGA1 140710
Proximity Label-MS Homo sapiens
173 ABCF3 55324
Proximity Label-MS Homo sapiens
174 POP1 10940
Co-fractionation Homo sapiens
175 ZNF598 90850
Proximity Label-MS Homo sapiens
176 CAMSAP3  
Proximity Label-MS Homo sapiens
177 ZC3H7A  
Proximity Label-MS Homo sapiens
178 DHX29 54505
Proximity Label-MS Homo sapiens
179 CKAP2  
Proximity Label-MS Homo sapiens
180 MEX3A  
Affinity Capture-RNA Homo sapiens
181 MIPEP  
Affinity Capture-MS Homo sapiens
182 ARHGAP21 57584
Proximity Label-MS Homo sapiens
183 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
184 YWHAZ 7534
Affinity Capture-MS Homo sapiens
185 TUBB4B 10383
Affinity Capture-MS Homo sapiens
186 SPECC1 92521
Proximity Label-MS Homo sapiens
187 GAS2L3  
Proximity Label-MS Homo sapiens
188 MYO19  
Affinity Capture-MS Homo sapiens
189 HOOK3 84376
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
190 SH3PXD2B 285590
Proximity Label-MS Homo sapiens
191 MCM4 4173
Co-fractionation Homo sapiens
192 NAP1L1 4673
Proximity Label-MS Homo sapiens
193 PLEKHA5 54477
Proximity Label-MS Homo sapiens
194 TTF2 8458
Proximity Label-MS Homo sapiens
195 Dynlrb1 67068
Affinity Capture-MS Mus musculus
196 SPTBN1 6711
Affinity Capture-Western Homo sapiens
197 NXF1 10482
Affinity Capture-RNA Homo sapiens
198 DUSP13  
Affinity Capture-MS Homo sapiens
199 Dctn2 69654
Affinity Capture-MS Mus musculus
Affinity Capture-MS Mus musculus
200 RANBP9 10048
Co-fractionation Homo sapiens
201 MAPRE3  
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
202 MAP7D1 55700
Proximity Label-MS Homo sapiens
203 TDRD3  
Proximity Label-MS Homo sapiens
204 ANKRD52 283373
Proximity Label-MS Homo sapiens
205 MTUS1  
Proximity Label-MS Homo sapiens
206 PCBP1 5093
Affinity Capture-MS Homo sapiens
207 STAT1 6772
Two-hybrid Homo sapiens
208 MYO6 4646
Affinity Capture-MS Homo sapiens
209 ZC2HC1A 51101
Proximity Label-MS Homo sapiens
210 BICD2 23299
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
211 DYNC1LI1 51143
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
212 CEP170B  
Proximity Label-MS Homo sapiens
213 CCDC138  
Proximity Label-MS Homo sapiens
214 ESD 2098
Affinity Capture-MS Homo sapiens
215 SEC16A 9919
Affinity Capture-MS Homo sapiens
216 MAP9 79884
Proximity Label-MS Homo sapiens
217 GSTK1 373156
Affinity Capture-MS Homo sapiens
218 EPB41 2035
Affinity Capture-Western Homo sapiens
219 C16orf45  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
220 SH3D19 152503
Proximity Label-MS Homo sapiens
221 NDC80 10403
Proximity Label-MS Homo sapiens
222 MATR3 9782
Co-fractionation Homo sapiens
223 Actr1a 54130
Affinity Capture-MS Mus musculus
224 EDF1 8721
Proximity Label-MS Homo sapiens
225 SF3B3 23450
Co-fractionation Homo sapiens
226 KIAA0368 23392
Co-localization Homo sapiens
227 CEP72  
Proximity Label-MS Homo sapiens
228 CCDC88A 55704
Affinity Capture-Western Homo sapiens
229 AKT1 207
Two-hybrid Homo sapiens
230 CEP350 9857
Proximity Label-MS Homo sapiens
231 TSR1 55720
Proximity Label-MS Homo sapiens
232 MAP7D2 256714
Proximity Label-MS Homo sapiens
233 Ccdc64b  
Affinity Capture-Western Mus musculus
234 IRF3 3661
Affinity Capture-MS Homo sapiens
235 KLHL2 11275
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
236 EIF3D 8664
Co-fractionation Homo sapiens
237 MPHOSPH9  
Proximity Label-MS Homo sapiens
238 PAFAH1B1 5048
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
239 YTHDC2 64848
Proximity Label-MS Homo sapiens
240 SPICE1  
Proximity Label-MS Homo sapiens
241 KIF2A 3796
Proximity Label-MS Homo sapiens
242 CEP290  
Proximity Label-MS Homo sapiens
243 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
244 FASN 2194
Negative Genetic Homo sapiens
245 HSPB2  
Two-hybrid Homo sapiens
246 PDGFD 80310
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
247 GRB2 2885
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
248 AHI1  
Affinity Capture-MS Homo sapiens
249 UBE2O 63893
Proximity Label-MS Homo sapiens
250 MACF1 23499
Proximity Label-MS Homo sapiens
251 CKAP2L  
Proximity Label-MS Homo sapiens
252 Dync1li1 235661
Affinity Capture-MS Mus musculus
253 DNAJA2 10294
Co-fractionation Homo sapiens
254 STRN4 29888
Co-fractionation Homo sapiens
255 SAP30BP  
Co-fractionation Homo sapiens
256 CENPJ 55835
Proximity Label-MS Homo sapiens
257 MTERF1  
Reconstituted Complex Homo sapiens
258 Capza1 12340
Affinity Capture-MS Mus musculus
259 Myo1c 17913
Affinity Capture-MS Mus musculus
260 CDC37 11140
Two-hybrid Homo sapiens
261 ZKSCAN1  
Affinity Capture-MS Homo sapiens
262 Ccdc64  
Affinity Capture-Western Mus musculus
263 CAPZA2 830
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
264 MAPRE2 10982
Proximity Label-MS Homo sapiens
265 VPS26A 9559
Co-fractionation Homo sapiens
266 ACTR1B 10120
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
267 DCTN2 10540
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
268 HAUS5 23354
Proximity Label-MS Homo sapiens
269 PRR36 80164
Proximity Label-MS Homo sapiens
270 EIF2A 83939
Co-fractionation Homo sapiens
271 DDX58 23586
Affinity Capture-RNA Homo sapiens
272 MAP7D3 79649
Proximity Label-MS Homo sapiens
273 PACSIN3 29763
Co-fractionation Homo sapiens
274 DYNC1H1 1778
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
275 CEP44  
Proximity Label-MS Homo sapiens
276 UFL1 23376
Affinity Capture-MS Homo sapiens
277 NF1 4763
Negative Genetic Homo sapiens
278 CLASP1 23332
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
279 DSTYK 25778
Affinity Capture-MS Homo sapiens
280 NEK2  
Two-hybrid Homo sapiens
281 DCDC2  
Proximity Label-MS Homo sapiens
282 MOV10 4343
Affinity Capture-RNA Homo sapiens
283 CEP162  
Proximity Label-MS Homo sapiens
284 Dctn3  
Affinity Capture-MS Mus musculus
Affinity Capture-MS Mus musculus
285 TMEM79  
Proximity Label-MS Homo sapiens
286 TRIM36  
Proximity Label-MS Homo sapiens
287 NEDD1 121441
Proximity Label-MS Homo sapiens
288 FAM161A  
Proximity Label-MS Homo sapiens
289 IBTK 25998
Proximity Label-MS Homo sapiens
290 ACTA2 59
Affinity Capture-MS Homo sapiens
291 DYNLRB1 83658
Affinity Capture-Western Homo sapiens
292 IFT74 80173
Proximity Label-MS Homo sapiens
293 MISP 126353
Affinity Capture-Western Homo sapiens
294 FLNC 2318
Co-fractionation Homo sapiens
295 SNW1 22938
Affinity Capture-MS Homo sapiens
296 LTV1  
Proximity Label-MS Homo sapiens
297 C9orf72  
Affinity Capture-MS Homo sapiens
298 TRIM29 23650
Affinity Capture-MS Homo sapiens
299 VIM 7431
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
300 RPA3 6119
Proximity Label-MS Homo sapiens
301 GAPDH 2597
Cross-Linking-MS (XL-MS) Homo sapiens
302 KIAA0408  
Two-hybrid Homo sapiens
303 WDHD1  
Co-fractionation Homo sapiens
304 WDR62  
Proximity Label-MS Homo sapiens
305 NIN 51199
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
306 CUL4A 8451
Affinity Capture-MS Homo sapiens
307 CC2D1A 54862
Proximity Label-MS Homo sapiens
308 CCSER2 54462
Proximity Label-MS Homo sapiens
309 SKA1  
Proximity Label-MS Homo sapiens
View the network image/svg+xml
 Pathways in which DCTN1 is involved
PathwayEvidenceSource
Adaptive Immune System TAS Reactome
Anchoring of the basal body to the plasma membrane TAS Reactome
Asparagine N-linked glycosylation TAS Reactome
AURKA Activation by TPX2 TAS Reactome
Cell Cycle TAS Reactome
Cell Cycle, Mitotic TAS Reactome
Cellular responses to stimuli TAS Reactome
Cellular responses to stress TAS Reactome
Centrosome maturation TAS Reactome
Cilium Assembly TAS Reactome
COPI-independent Golgi-to-ER retrograde traffic TAS Reactome
COPI-mediated anterograde transport TAS Reactome
Disease TAS Reactome
Diseases of signal transduction by growth factor receptors and second messengers TAS Reactome
ER to Golgi Anterograde Transport TAS Reactome
G2/M Transition TAS Reactome
Golgi-to-ER retrograde transport TAS Reactome
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand TAS Reactome
Immune System TAS Reactome
Intra-Golgi and retrograde Golgi-to-ER traffic TAS Reactome
IRE1alpha activates chaperones TAS Reactome
Loss of Nlp from mitotic centrosomes TAS Reactome
Loss of proteins required for interphase microtubule organization from the centrosome TAS Reactome
M Phase TAS Reactome
Membrane Trafficking TAS Reactome
Metabolism of proteins TAS Reactome
MHC class II antigen presentation TAS Reactome
Mitotic G2-G2/M phases TAS Reactome
Mitotic Prometaphase TAS Reactome
Organelle biogenesis and maintenance TAS Reactome
Post-translational protein modification TAS Reactome
Recruitment of mitotic centrosome proteins and complexes TAS Reactome
Recruitment of NuMA to mitotic centrosomes TAS Reactome
Regulation of PLK1 Activity at G2/M Transition TAS Reactome
Signaling by ALK fusions and activated point mutants TAS Reactome
Signaling by ALK in cancer TAS Reactome
Transport to the Golgi and subsequent modification TAS Reactome
Unfolded Protein Response (UPR) TAS Reactome
Vesicle-mediated transport TAS Reactome
XBP1(S) activates chaperone genes TAS Reactome





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