Gene description for G3BP2
Gene name GTPase activating protein (SH3 domain) binding protein 2
Gene symbol G3BP2
Other names/aliases -
Species Homo sapiens
 Database cross references - G3BP2
ExoCarta ExoCarta_9908
Vesiclepedia VP_9908
Entrez Gene 9908
HGNC 30291
UniProt Q9UN86  
 G3BP2 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
 Gene ontology annotations for G3BP2
Molecular Function
    RNA binding GO:0003723 HDA
    mRNA binding GO:0003729 IBA
    protein binding GO:0005515 IPI
    signaling receptor complex adaptor activity GO:0030159 NAS
    molecular condensate scaffold activity GO:0140693 IBA
    molecular condensate scaffold activity GO:0140693 IDA
Biological Process
    cytoplasmic sequestering of NF-kappaB GO:0007253 NAS
    Ras protein signal transduction GO:0007265 NAS
    stress granule assembly GO:0034063 IBA
    stress granule assembly GO:0034063 IDA
    innate immune response GO:0045087 IEA
    mRNA transport GO:0051028 IEA
    protein homooligomerization GO:0051260 IMP
    positive regulation of stress granule assembly GO:0062029 IMP
Subcellular Localization
    cytoplasm GO:0005737 NAS
    cytosol GO:0005829 IBA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    cytoplasmic stress granule GO:0010494 IBA
    cytoplasmic stress granule GO:0010494 IMP
 Experiment description of studies that identified G3BP2 in sEVs
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 407
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 419
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 419
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 420
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 420
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 405
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
15
Experiment ID 363
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 364
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 365
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 417
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 411
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
21
Experiment ID 418
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 418
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 413
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 211
MISEV standards
EM
Biophysical techniques
TSG101|Alix|EpCAM|TFRC
Enriched markers
cytochrome c|GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
25
Experiment ID 212
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|EpCAM|TFRC
Enriched markers
Cytochrome C|GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
26
Experiment ID 406
MISEV standards
EM
Biophysical techniques
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 415
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 434
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
29
Experiment ID 435
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
30
Experiment ID 408
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 409
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 416
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
33
Experiment ID 191
MISEV standards
Biophysical techniques
Alix|CD81|CD9
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
34
Experiment ID 410
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for G3BP2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GNL2 29889
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
3 EIF3A 8661
Affinity Capture-MS Homo sapiens
4 RPS12 6206
Affinity Capture-MS Homo sapiens
5 RPSA 3921
Affinity Capture-MS Homo sapiens
6 IGF2BP1 10642
Affinity Capture-MS Homo sapiens
7 METTL17  
Affinity Capture-MS Homo sapiens
8 KLF8  
Affinity Capture-MS Homo sapiens
9 TRMT1L 81627
Affinity Capture-MS Homo sapiens
10 RPS28 6234
Affinity Capture-MS Homo sapiens
11 TTC37 9652
Affinity Capture-MS Homo sapiens
12 COIL  
Affinity Capture-MS Homo sapiens
13 RPS3A 6189
Affinity Capture-MS Homo sapiens
14 EIF2S2 8894
Affinity Capture-MS Homo sapiens
15 DCP1B  
Affinity Capture-MS Homo sapiens
16 EIF3C 8663
Affinity Capture-MS Homo sapiens
17 RPL30 6156
Affinity Capture-MS Homo sapiens
18 H1FX 8971
Affinity Capture-MS Homo sapiens
19 TOP2B 7155
Affinity Capture-MS Homo sapiens
20 RFC4 5984
Affinity Capture-MS Homo sapiens
21 QARS 5859
Affinity Capture-MS Homo sapiens
22 TARDBP 23435
Affinity Capture-MS Homo sapiens
23 FMR1 2332
Affinity Capture-MS Homo sapiens
24 BTF3 689
Affinity Capture-MS Homo sapiens
25 RPS2 6187
Affinity Capture-MS Homo sapiens
26 NUP62 23636
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 G3BP1 10146
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
28 RPL26L1 51121
Affinity Capture-MS Homo sapiens
29 RPS19 6223
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
30 RPL10 6134
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 KIF20A 10112
Affinity Capture-MS Homo sapiens
32 UBC 7316
Affinity Capture-MS Homo sapiens
33 POM121  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 EIF4A1 1973
Affinity Capture-MS Homo sapiens
35 USP19 10869
Affinity Capture-MS Homo sapiens
36 CAND1 55832
Affinity Capture-MS Homo sapiens
37 LRRC59 55379
Affinity Capture-MS Homo sapiens
38 SRP72 6731
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 PPP1R10  
Affinity Capture-MS Homo sapiens
40 SOX2  
Affinity Capture-MS Homo sapiens
41 ZNF618  
Two-hybrid Homo sapiens
42 WDR36 134430
Affinity Capture-MS Homo sapiens
43 RIOK1 83732
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
44 GRB7 2886
Affinity Capture-MS Homo sapiens
45 RPS18 6222
Affinity Capture-MS Homo sapiens
46 RNH1 6050
Affinity Capture-MS Homo sapiens
47 CAPZB 832
Affinity Capture-MS Homo sapiens
48 PARK2  
Affinity Capture-MS Homo sapiens
49 RPS20 6224
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 IGF2BP3 10643
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 RPL7A 6130
Affinity Capture-MS Homo sapiens
52 LASP1 3927
Affinity Capture-MS Homo sapiens
53 KIF23 9493
Affinity Capture-MS Homo sapiens
54 DDX24 57062
Affinity Capture-MS Homo sapiens
55 ATXN2L 11273
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
56 NUP153 9972
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
57 HDLBP 3069
Affinity Capture-MS Homo sapiens
58 EIF3B 8662
Affinity Capture-MS Homo sapiens
59 COPS5 10987
Affinity Capture-MS Homo sapiens
60 PRC1 9055
Affinity Capture-MS Homo sapiens
61 HGS 9146
Affinity Capture-MS Homo sapiens
62 NPM1 4869
Affinity Capture-MS Homo sapiens
63 HSPH1 10808
Affinity Capture-MS Homo sapiens
64 RPS8 6202
Affinity Capture-MS Homo sapiens
65 FBXW8 26259
Affinity Capture-MS Homo sapiens
66 SRP19 6728
Affinity Capture-MS Homo sapiens
67 OBSL1 23363
Affinity Capture-MS Homo sapiens
68 RPL24 6152
Affinity Capture-MS Homo sapiens
69 RPS9 6203
Affinity Capture-MS Homo sapiens
70 ABCE1 6059
Affinity Capture-MS Homo sapiens
71 RPF2 84154
Affinity Capture-MS Homo sapiens
72 EIF4G1 1981
Affinity Capture-MS Homo sapiens
73 KTN1 3895
Affinity Capture-MS Homo sapiens
74 SRP68 6730
Affinity Capture-MS Homo sapiens
75 GNL3 26354
Affinity Capture-MS Homo sapiens
76 ATG16L1 55054
Affinity Capture-MS Homo sapiens
77 DDX6 1656
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
78 SFN 2810
Affinity Capture-MS Homo sapiens
79 MTDH 92140
Affinity Capture-MS Homo sapiens
80 FARS2 10667
Affinity Capture-MS Homo sapiens
81 ERMAP 114625
Affinity Capture-MS Homo sapiens
82 POP1 10940
Affinity Capture-MS Homo sapiens
83 LTV1  
Affinity Capture-MS Homo sapiens
84 CUL1 8454
Affinity Capture-MS Homo sapiens
85 MYCN  
Affinity Capture-MS Homo sapiens
86 CSNK1D 1453
Affinity Capture-MS Homo sapiens
87 USP7 7874
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
88 RPS11 6205
Affinity Capture-MS Homo sapiens
89 RPL34 6164
Affinity Capture-MS Homo sapiens
90 GNB2L1 10399
Affinity Capture-MS Homo sapiens
91 PABPC4 8761
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
92 FAM120A 23196
Affinity Capture-MS Homo sapiens
93 RBM8A 9939
Affinity Capture-MS Homo sapiens
94 KIF14 9928
Affinity Capture-MS Homo sapiens
95 RPS26 6231
Affinity Capture-MS Homo sapiens
96 LSM12 124801
Affinity Capture-MS Homo sapiens
97 ADSL 158
Co-fractionation Homo sapiens
98 EIF2S3 1968
Affinity Capture-MS Homo sapiens
99 KLF16  
Affinity Capture-MS Homo sapiens
100 EDC4 23644
Affinity Capture-MS Homo sapiens
101 RPS23 6228
Affinity Capture-MS Homo sapiens
102 NF2 4771
Affinity Capture-MS Homo sapiens
103 RPL27 6155
Affinity Capture-MS Homo sapiens
104 RPL22L1 200916
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
105 EIF3K 27335
Affinity Capture-MS Homo sapiens
106 RPS16 6217
Affinity Capture-MS Homo sapiens
107 ING4  
Affinity Capture-Western Homo sapiens
108 PRPF8 10594
Co-fractionation Homo sapiens
109 USP10 9100
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
110 RPL9 6133
Affinity Capture-MS Homo sapiens
111 SRP14 6727
Affinity Capture-MS Homo sapiens
112 UBAP2 55833
Affinity Capture-MS Homo sapiens
113 MEPCE 56257
Affinity Capture-MS Homo sapiens
114 STAU1 6780
Affinity Capture-MS Homo sapiens
115 RPS15 6209
Affinity Capture-MS Homo sapiens
116 DRG1 4733
Affinity Capture-MS Homo sapiens
117 MARS 4141
Affinity Capture-MS Homo sapiens
118 UBAP2L 9898
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
119 ADAR 103
Affinity Capture-MS Homo sapiens
120 EIF3E 3646
Affinity Capture-MS Homo sapiens
121 RPL32 6161
Affinity Capture-MS Homo sapiens
122 PNO1 56902
Affinity Capture-MS Homo sapiens
123 WDR61 80349
Affinity Capture-MS Homo sapiens
124 RPL5 6125
Affinity Capture-MS Homo sapiens
125 RPL18A 6142
Affinity Capture-MS Homo sapiens
126 PABPC1 26986
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
127 DDX10  
Affinity Capture-MS Homo sapiens
128 CHMP4B 128866
Affinity Capture-MS Homo sapiens
129 RPS25 6230
Affinity Capture-MS Homo sapiens
130 VCP 7415
Affinity Capture-MS Homo sapiens
131 NTRK1 4914
Affinity Capture-MS Homo sapiens
132 RPL31 6160
Affinity Capture-MS Homo sapiens
133 DHX9 1660
Affinity Capture-MS Homo sapiens
134 RPS7 6201
Affinity Capture-MS Homo sapiens
135 IFI16 3428
Affinity Capture-MS Homo sapiens
136 RPL13A 23521
Affinity Capture-MS Homo sapiens
137 NSRP1  
Affinity Capture-MS Homo sapiens
138 DHX29 54505
Affinity Capture-MS Homo sapiens
139 NOB1  
Affinity Capture-MS Homo sapiens
140 LYAR 55646
Affinity Capture-MS Homo sapiens
141 RPS6 6194
Affinity Capture-MS Homo sapiens
142 ANXA1 301
Protein-peptide Homo sapiens
143 IARS 3376
Affinity Capture-MS Homo sapiens
144 TRIM72  
Affinity Capture-Western Homo sapiens
145 UPF1 5976
Affinity Capture-MS Homo sapiens
146 SND1 27044
Affinity Capture-MS Homo sapiens
147 RPS15A 6210
Affinity Capture-MS Homo sapiens
148 CNOT10 25904
Affinity Capture-MS Homo sapiens
149 CEBPA  
Protein-peptide Homo sapiens
150 SEC61B 10952
Affinity Capture-MS Homo sapiens
151 CYLD  
Affinity Capture-MS Homo sapiens
152 FAM76A  
Affinity Capture-MS Homo sapiens
153 C7orf50 84310
Affinity Capture-MS Homo sapiens
154 CA9 768
Affinity Capture-MS Homo sapiens
155 LARP1 23367
Affinity Capture-MS Homo sapiens
156 RSL1D1 26156
Affinity Capture-MS Homo sapiens
157 ANLN 54443
Affinity Capture-MS Homo sapiens
158 PA2G4 5036
Affinity Capture-MS Homo sapiens
159 HNRNPD 3184
Affinity Capture-MS Homo sapiens
160 EIF3G 8666
Affinity Capture-MS Homo sapiens
161 OGT 8473
Reconstituted Complex Homo sapiens
162 FAM76B  
Affinity Capture-MS Homo sapiens
163 ASCC3 10973
Affinity Capture-MS Homo sapiens
164 RPL28 6158
Affinity Capture-MS Homo sapiens
165 RPL10A 4736
Affinity Capture-MS Homo sapiens
166 RPLP2 6181
Affinity Capture-MS Homo sapiens
167 RPS24 6229
Affinity Capture-MS Homo sapiens
168 RPL23 9349
Affinity Capture-MS Homo sapiens
169 RPL13 6137
Affinity Capture-MS Homo sapiens
170 NR3C1 2908
Proximity Label-MS Homo sapiens
171 RC3H2  
Affinity Capture-MS Homo sapiens
172 ECT2 1894
Affinity Capture-MS Homo sapiens
173 CCDC124 115098
Affinity Capture-MS Homo sapiens
174 RPL35 11224
Affinity Capture-MS Homo sapiens
175 NFKBIA  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
176 IFI30  
Co-fractionation Homo sapiens
177 NUP88 4927
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
178 RPL14 9045
Affinity Capture-MS Homo sapiens
179 CUL3 8452
Affinity Capture-MS Homo sapiens
180 PTEN 5728
Affinity Capture-MS Homo sapiens
181 RPL21 6144
Affinity Capture-MS Homo sapiens
182 RPL3 6122
Affinity Capture-MS Homo sapiens
183 HSD17B10 3028
Affinity Capture-MS Homo sapiens
184 H1F0 3005
Affinity Capture-MS Homo sapiens
185 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
186 DHX30 22907
Affinity Capture-MS Homo sapiens
187 ACE2 59272
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
188 RPS17 6218
Affinity Capture-MS Homo sapiens
189 RPL7 6129
Affinity Capture-MS Homo sapiens
190 PPP1R12A 4659
Co-fractionation Homo sapiens
191 SUZ12  
Affinity Capture-MS Homo sapiens
192 RPLP1 6176
Affinity Capture-MS Homo sapiens
193 GLUD1 2746
Affinity Capture-MS Homo sapiens
194 DHX57 90957
Affinity Capture-MS Homo sapiens
195 AURKB 9212
Affinity Capture-MS Homo sapiens
196 CCNT2  
Affinity Capture-MS Homo sapiens
197 RPS27 6232
Affinity Capture-MS Homo sapiens
198 CDK2 1017
Affinity Capture-MS Homo sapiens
199 RPL29 6159
Affinity Capture-MS Homo sapiens
200 RPL36 25873
Affinity Capture-MS Homo sapiens
201 EDF1 8721
Affinity Capture-MS Homo sapiens
202 MYC  
Affinity Capture-MS Homo sapiens
203 FXR2 9513
Affinity Capture-MS Homo sapiens
204 RPS13 6207
Affinity Capture-MS Homo sapiens
205 PRRC2A 7916
Affinity Capture-MS Homo sapiens
206 EXOSC3 51010
Affinity Capture-MS Homo sapiens
207 RPS14 6208
Affinity Capture-MS Homo sapiens
208 RPL12 6136
Affinity Capture-MS Homo sapiens
209 RPL27A 6157
Affinity Capture-MS Homo sapiens
210 RPL22 6146
Affinity Capture-MS Homo sapiens
211 HP1BP3 50809
Affinity Capture-MS Homo sapiens
212 NUP214 8021
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
213 FAU 2197
Affinity Capture-MS Homo sapiens
214 RPL23A 6147
Affinity Capture-MS Homo sapiens
215 RPL18 6141
Affinity Capture-MS Homo sapiens
216 DDRGK1 65992
Affinity Capture-MS Homo sapiens
217 RNF2  
Affinity Capture-MS Homo sapiens
218 BMI1  
Affinity Capture-MS Homo sapiens
219 GLA 2717
Affinity Capture-MS Homo sapiens
220 CNOT11 55571
Affinity Capture-MS Homo sapiens
221 RPL11 6135
Affinity Capture-MS Homo sapiens
222 RPS10 6204
Affinity Capture-MS Homo sapiens
223 TSR1 55720
Affinity Capture-MS Homo sapiens
224 EXOSC2 23404
Affinity Capture-MS Homo sapiens
225 LARP4 113251
Affinity Capture-MS Homo sapiens
226 MDM2  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
227 RPL15 6138
Affinity Capture-MS Homo sapiens
228 FXR1 8087
Affinity Capture-MS Homo sapiens
229 C3orf17  
Affinity Capture-MS Homo sapiens
230 AIMP1 9255
Affinity Capture-MS Homo sapiens
231 CKMT2  
Affinity Capture-MS Homo sapiens
232 RRBP1 6238
Affinity Capture-MS Homo sapiens
233 CBX4  
Affinity Capture-MS Homo sapiens
234 HECTD1 25831
Affinity Capture-MS Homo sapiens
235 TLX1  
Affinity Capture-MS Homo sapiens
236 EIF2S1 1965
Affinity Capture-MS Homo sapiens
237 SRP54 6729
Affinity Capture-MS Homo sapiens
238 EIF3H 8667
Affinity Capture-MS Homo sapiens
239 ARRB2 409
Affinity Capture-MS Homo sapiens
240 UIMC1  
Affinity Capture-MS Homo sapiens
241 RPL3L 6123
Affinity Capture-MS Homo sapiens
242 STK24 8428
Affinity Capture-MS Homo sapiens
243 SPOP  
Affinity Capture-MS Homo sapiens
244 TERF2  
Affinity Capture-MS Homo sapiens
245 SIRT6  
Affinity Capture-MS Homo sapiens
246 MTPN 136319
Affinity Capture-MS Homo sapiens
247 PDE4B  
Protein-RNA Homo sapiens
248 ILF3 3609
Affinity Capture-MS Homo sapiens
249 WDR77 79084
Affinity Capture-MS Homo sapiens
250 LARP4B 23185
Affinity Capture-MS Homo sapiens
251 TP53 7157
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
252 RPL6 6128
Affinity Capture-MS Homo sapiens
253 NOMO3 408050
Affinity Capture-MS Homo sapiens
254 RPS21 6227
Affinity Capture-MS Homo sapiens
255 EIF3I 8668
Affinity Capture-MS Homo sapiens
256 ZEB1  
Affinity Capture-MS Homo sapiens
257 TPR 7175
Co-fractionation Homo sapiens
258 PIN1 5300
Reconstituted Complex Homo sapiens
259 KLHDC3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
260 PRRC2C 23215
Affinity Capture-MS Homo sapiens
261 NUFIP2 57532
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
262 PDCD4 27250
Affinity Capture-MS Homo sapiens
263 SSR4 6748
Affinity Capture-MS Homo sapiens
264 RPS4X 6191
Affinity Capture-MS Homo sapiens
265 SQSTM1 8878
Affinity Capture-Western Homo sapiens
266 YARS 8565
Co-fractionation Homo sapiens
267 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
268 CAPRIN1 4076
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
269 PRMT5 10419
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
270 ZC3H15 55854
Affinity Capture-MS Homo sapiens
271 RPS5 6193
Affinity Capture-MS Homo sapiens
272 PRRC2B  
Affinity Capture-MS Homo sapiens
273 TRIM25 7706
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
274 TOP2A 7153
Affinity Capture-MS Homo sapiens
275 ESR1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
276 UFL1 23376
Affinity Capture-MS Homo sapiens
277 WWP2 11060
Affinity Capture-MS Homo sapiens
278 EIF3F 8665
Affinity Capture-MS Homo sapiens
279 SNIP1  
Affinity Capture-MS Homo sapiens
280 RPL38 6169
Affinity Capture-MS Homo sapiens
281 MED12  
Affinity Capture-MS Homo sapiens
282 NCL 4691
Affinity Capture-MS Homo sapiens
283 GTPBP4 23560
Affinity Capture-MS Homo sapiens
284 HNRNPL 3191
Affinity Capture-MS Homo sapiens
285 EIF3M 10480
Affinity Capture-MS Homo sapiens
286 EIF4B 1975
Affinity Capture-MS Homo sapiens
287 TRIP4 9325
Affinity Capture-MS Homo sapiens
288 TRIM31  
Affinity Capture-MS Homo sapiens
289 CIT 11113
Affinity Capture-MS Homo sapiens
290 RPL8 6132
Affinity Capture-MS Homo sapiens
291 C14orf166 51637
Affinity Capture-MS Homo sapiens
292 GRSF1 2926
Proximity Label-MS Homo sapiens
293 RPS27L 51065
Affinity Capture-MS Homo sapiens
294 SERBP1 26135
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
295 RPLP0 6175
Affinity Capture-MS Homo sapiens
296 SNW1 22938
Affinity Capture-MS Homo sapiens
297 KRAS 3845
Affinity Capture-MS Homo sapiens
298 RARS 5917
Affinity Capture-MS Homo sapiens
299 C9orf72  
Affinity Capture-MS Homo sapiens
300 RPL4 6124
Affinity Capture-MS Homo sapiens
301 RC3H1 149041
Affinity Capture-MS Homo sapiens
302 CKAP4 10970
Affinity Capture-MS Homo sapiens
303 IVNS1ABP  
Affinity Capture-MS Homo sapiens
304 RPS3 6188
Affinity Capture-MS Homo sapiens
305 PRMT1 3276
Affinity Capture-MS Homo sapiens
306 EPRS 2058
Affinity Capture-MS Homo sapiens
307 SDAD1  
Affinity Capture-MS Homo sapiens
308 RPL17 6139
Affinity Capture-MS Homo sapiens
309 EP300 2033
Affinity Capture-MS Homo sapiens
310 EIF3J 8669
Affinity Capture-MS Homo sapiens
311 EIF3L 51386
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here