Gene description for KLK11
Gene name kallikrein-related peptidase 11
Gene symbol KLK11
Other names/aliases PRSS20
TLSP
Species Homo sapiens
 Database cross references - KLK11
ExoCarta ExoCarta_11012
Vesiclepedia VP_11012
Entrez Gene 11012
HGNC 6359
MIM 604434
UniProt Q9UBX7  
 KLK11 identified in sEVs derived from the following tissue/cell type
Keratinocytes 19530224    
Keratinocytes 19530224    
 Gene ontology annotations for KLK11
Molecular Function
    serine-type endopeptidase activity GO:0004252 IBA
    serine-type peptidase activity GO:0008236 TAS
Biological Process
    proteolysis GO:0006508 IEA
    protein maturation GO:0051604 IBA
Subcellular Localization
    extracellular space GO:0005615 HDA
    extracellular space GO:0005615 IBA
    Golgi apparatus GO:0005794 IEA
    secretory granule GO:0030141 IBA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified KLK11 in sEVs
1
Experiment ID 189
MISEV standards
EM
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors "Chavez-Muñoz C, Kilani RT, Ghahary A."
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Differentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 190
MISEV standards
EM
Biophysical techniques
HSC70
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors "Chavez-Muñoz C, Kilani RT, Ghahary A."
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Undifferentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for KLK11
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 AP3S1 1176
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 NEU3  
Affinity Capture-MS Homo sapiens
3 WDR34 89891
Affinity Capture-MS Homo sapiens
4 PCDH20  
Affinity Capture-MS Homo sapiens
5 POLE2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 MOCOS  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 FAT1 2195
Affinity Capture-MS Homo sapiens
8 RB1 5925
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 VMP1 81671
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 KIAA1147  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 SPINT2 10653
Affinity Capture-MS Homo sapiens
12 LOXL2 4017
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 TUBB3 10381
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 CHD1L 9557
Affinity Capture-MS Homo sapiens
15 TBL3 10607
Affinity Capture-MS Homo sapiens
16 FTH1 2495
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 TUBA1A 7846
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 SPSB3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 TUBA4A 7277
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 MANBA 4126
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
21 CHPT1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 TUBA1C 84790
Affinity Capture-MS Homo sapiens
23 GALNT11 63917
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 C19orf52  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 FRAS1 80144
Affinity Capture-MS Homo sapiens
26 ERAP1 51752
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 TGFBR3 7049
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 CCR1  
Affinity Capture-MS Homo sapiens
29 CBWD1 55871
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 TXNDC11 51061
Affinity Capture-MS Homo sapiens
31 RPL29 6159
Co-fractionation Homo sapiens
View the network image/svg+xml
 Pathways in which KLK11 is involved
No pathways found





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