Gene description for Prdx3
Gene name	peroxiredoxin 3
Gene symbol	Prdx3
Other names/aliases	AW822249 Aop1 D0Tohi1 Ef2l Mer5 Prx3 SP22 TDXM
Species	Mus musculus
Database cross references - Prdx3
ExoCarta	ExoCarta_11757
Vesiclepedia	VP_11757
Entrez Gene	11757
UniProt	P20108
Prdx3 identified in sEVs derived from the following tissue/cell type
Melanoma cells	34957415
Melanoma cells	34957415
Pancreatic cells	19351151

Gene ontology annotations for Prdx3

Molecular Function     thioredoxin peroxidase activity GO:0008379 IBA     thioredoxin peroxidase activity GO:0008379 IEA     thioredoxin peroxidase activity GO:0008379 ISO     protein kinase binding GO:0019901 IEA     protein kinase binding GO:0019901 ISO     identical protein binding GO:0042802 IPI     identical protein binding GO:0042802 ISO     cysteine-type endopeptidase inhibitor activity involved in apoptotic process GO:0043027 IEA     cysteine-type endopeptidase inhibitor activity involved in apoptotic process GO:0043027 ISO Biological Process     maternal placenta development GO:0001893 IMP     response to oxidative stress GO:0006979 IBA     response to oxidative stress GO:0006979 IMP     response to oxidative stress GO:0006979 ISO     mitochondrion organization GO:0007005 IEA     mitochondrion organization GO:0007005 ISO     positive regulation of cell population proliferation GO:0008284 IEA     positive regulation of cell population proliferation GO:0008284 ISO     peptidyl-cysteine oxidation GO:0018171 ISO     myeloid cell differentiation GO:0030099 IMP     response to lipopolysaccharide GO:0032496 IMP     negative regulation of kinase activity GO:0033673 ISO     cellular response to oxidative stress GO:0034599 ISO     cellular response to reactive oxygen species GO:0034614 IEA     cellular response to reactive oxygen species GO:0034614 ISO     response to hydrogen peroxide GO:0042542 IEA     response to hydrogen peroxide GO:0042542 ISO     hydrogen peroxide catabolic process GO:0042744 IBA     hydrogen peroxide catabolic process GO:0042744 ISO     hydrogen peroxide catabolic process GO:0042744 ISO     negative regulation of apoptotic process GO:0043066 IEA     negative regulation of apoptotic process GO:0043066 ISO     negative regulation of neuron apoptotic process GO:0043524 ISO     cell redox homeostasis GO:0045454 IBA     positive regulation of NF-kappaB transcription factor activity GO:0051092 ISO     regulation of mitochondrial membrane potential GO:0051881 IEA     regulation of mitochondrial membrane potential GO:0051881 ISO     cellular oxidant detoxification GO:0098869 IEA Subcellular Localization     nucleoplasm GO:0005654 IEA     nucleoplasm GO:0005654 ISO     cytoplasm GO:0005737 ISO     mitochondrion GO:0005739 HDA     mitochondrion GO:0005739 IBA     mitochondrion GO:0005739 ISO     early endosome GO:0005769 IEA     early endosome GO:0005769 ISO     cytosol GO:0005829 IBA     cytosol GO:0005829 IEA     cytosol GO:0005829 ISO     plasma membrane GO:0005886 IEA     plasma membrane GO:0005886 ISO     protein-containing complex GO:0032991 IEA     protein-containing complex GO:0032991 ISO     myelin sheath GO:0043209 HDA     intracellular membrane-bounded organelle GO:0043231 ISO