Gene description for Mgp
Gene name
matrix Gla protein
Gene symbol
Mgp
Other names/aliases
Mglap
Species
Mus musculus
Database cross references - Mgp
ExoCarta
ExoCarta_17313
Vesiclepedia
VP_17313
Entrez Gene
17313
UniProt
P19788
Mgp identified in sEVs derived from the following tissue/cell type
Colon cancer cells
37309723
T-cell lymphoma cells
37309723
Gene ontology annotations for Mgp
Experiment description of studies that identified Mgp in sEVs
1
Experiment ID
907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
Colon cancer cells
Sample name
C26
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
T-cell lymphoma cells
Sample name
EL4
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for Mgp
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
UBR5
51366
Affinity Capture-MS
Homo sapiens
2
HEATR1
55127
Affinity Capture-MS
Homo sapiens
3
CALU
813
Affinity Capture-MS
Homo sapiens
4
UBR4
23352
Affinity Capture-MS
Homo sapiens
5
LGALS3BP
3959
Affinity Capture-MS
Homo sapiens
6
TTI1
9675
Affinity Capture-MS
Homo sapiens
7
RNF219
Affinity Capture-MS
Homo sapiens
8
PKN3
29941
Affinity Capture-MS
Homo sapiens
9
GANAB
23193
Affinity Capture-MS
Homo sapiens
10
HNRNPM
4670
Affinity Capture-MS
Homo sapiens
11
SQSTM1
8878
Affinity Capture-MS
Homo sapiens
12
HADHB
3032
Affinity Capture-MS
Homo sapiens
13
UBR1
197131
Affinity Capture-MS
Homo sapiens
14
GGCX
2677
Affinity Capture-MS
Homo sapiens
15
RASAL2
9462
Affinity Capture-MS
Homo sapiens
16
HSP90B1
7184
Affinity Capture-MS
Homo sapiens
17
RCN1
5954
Affinity Capture-MS
Homo sapiens
View the network
image/svg+xml
Pathways in which Mgp is involved
No pathways found