Experiment description of studies that identified LEPROTL1 in sEVs

1 Experiment ID 224 MISEV standards ✔ EM|AFM Biophysical techniques ✔ Alix|TSG101|CD63|CD81 Enriched markers ✔ GOLGA2 Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25944692     Organism Homo sapiens Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S" Journal name Oncotarget Publication year 2015 Sample Neuroblastoma cells Sample name SH-SY5Y Isolation/purification methods Differential centrifugation Ultracentrifugation OptiPrep density gradient Flotation density 1.10 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting

Protein-protein interactions for LEPROTL1

Protein Interactor ExoCarta ID Identification method PubMed Species 1 TMEM19   Two-hybrid Homo sapiens 2 GJA8   Two-hybrid Homo sapiens 3 GPX8 493869 Two-hybrid Homo sapiens 4 PEX16 9409 Two-hybrid Homo sapiens 5 SDCBP 6386 Two-hybrid Homo sapiens 6 FFAR2   Two-hybrid Homo sapiens 7 RBFA   Two-hybrid Homo sapiens 8 TMEM42   Two-hybrid Homo sapiens 9 SSMEM1   Two-hybrid Homo sapiens 10 LEPROTL1 23484 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 11 GJA5 2702 Two-hybrid Homo sapiens 12 SYNDIG1   Two-hybrid Homo sapiens 13 VAPA 9218 Two-hybrid Homo sapiens 14 SLC16A2   Two-hybrid Homo sapiens 15 MALL   Two-hybrid Homo sapiens 16 KLRG1   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 17 UNK   Affinity Capture-RNA Homo sapiens 18 TMEM248 55069 Two-hybrid Homo sapiens 19 EHHADH 1962 Two-hybrid Homo sapiens 20 TSNARE1   Two-hybrid Homo sapiens 21 FCER1G 2207 Two-hybrid Homo sapiens 22 CLDN7 1366 Two-hybrid Homo sapiens 23 TMEM14B   Two-hybrid Homo sapiens 24 RNF5   Two-hybrid Homo sapiens 25 SMCO4   Two-hybrid Homo sapiens 26 ORMDL3 94103 Two-hybrid Homo sapiens 27 LMBR1   Two-hybrid Homo sapiens 28 ELAVL1 1994 Affinity Capture-RNA Homo sapiens 29 LRRC4C   Two-hybrid Homo sapiens 30 REEP4   Two-hybrid Homo sapiens 31 CD79A   Two-hybrid Homo sapiens 32 TMEM11 8834 Two-hybrid Homo sapiens 33 EMP1   Two-hybrid Homo sapiens 34 SFXN3 81855 Two-hybrid Homo sapiens 35 CREB3L1   Two-hybrid Homo sapiens 36 KCNJ6   Two-hybrid Homo sapiens 37 PAQR8   Two-hybrid Homo sapiens 38 TSPAN2 10100 Two-hybrid Homo sapiens 39 GPR152   Two-hybrid Homo sapiens 40 TMEM173   Two-hybrid Homo sapiens 41 EDA   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 42 MSR1   Two-hybrid Homo sapiens 43 GPR42   Two-hybrid Homo sapiens 44 CD300C   Two-hybrid Homo sapiens 45 ARL13B 200894 Two-hybrid Homo sapiens 46 TMEM237 65062 Two-hybrid Homo sapiens 47 TMEM50B 757 Two-hybrid Homo sapiens 48 CYP4F2   Two-hybrid Homo sapiens 49 TMEM50A 23585 Two-hybrid Homo sapiens 50 YIPF2 78992 Two-hybrid Homo sapiens 51 RTP2   Two-hybrid Homo sapiens 52 CISD2 493856 Two-hybrid Homo sapiens 53 TGFA   Two-hybrid Homo sapiens 54 PDZK1IP1 10158 Two-hybrid Homo sapiens 55 JPH1 56704 Two-hybrid Homo sapiens 56 NAT8   Two-hybrid Homo sapiens 57 PLP1 5354 Two-hybrid Homo sapiens 58 TVP23A   Two-hybrid Homo sapiens 59 SLC30A4 7782 Two-hybrid Homo sapiens 60 SCN3B   Two-hybrid Homo sapiens 61 ELOVL4   Two-hybrid Homo sapiens 62 LPAR3   Two-hybrid Homo sapiens 63 ZDHHC15 158866 Two-hybrid Homo sapiens 64 REEP6   Two-hybrid Homo sapiens 65 HIATL1 84641 Two-hybrid Homo sapiens 66 TMX2 51075 Two-hybrid Homo sapiens 67 SLC7A1 6541 Two-hybrid Homo sapiens 68 SLC25A46 91137 Two-hybrid Homo sapiens 69 STX12 23673 Two-hybrid Homo sapiens View the network

Pathways in which LEPROTL1 is involved

No pathways found