Experiment description of studies that identified ZNF451 in sEVs

1 Experiment ID 226 MISEV standards ✔ EM Biophysical techniques ✔ GAPDH|CD9|FLOT1 Enriched markers ✔ LMNA|H2AFX|ATP5A1|TOMM20 Negative markers ✘ Particle analysis Identified molecule mRNA Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa) PubMed ID 26027894     Organism Homo sapiens Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting" Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar" Journal name Journal of Extracellular Vesicles Publication year 2015 Sample Endothelial cells Sample name HMEC-1 Isolation/purification methods Differential ultracentrifugation Sucrose density gradient Flotation density 1.10 g/mL Molecules identified in the study miRNA Protein snoRNA lncRNA yRNA snRNA mRNA ncRNA mtRNA vtRNA scaRNA lincRNA Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa) Western blotting

Protein-protein interactions for ZNF451

Protein Interactor ExoCarta ID Identification method PubMed Species 1 NEURL4   Affinity Capture-MS Homo sapiens 2 SENP3 26168 Affinity Capture-MS Homo sapiens 3 RNF40 9810 Two-hybrid Homo sapiens 4 RAP1GDS1 5910 Two-hybrid Homo sapiens 5 CDCA4 55038 Two-hybrid Homo sapiens 6 PARP1 142 Proximity Label-MS Homo sapiens 7 CLU 1191 Affinity Capture-MS Homo sapiens 8 FAM118A   Two-hybrid Homo sapiens 9 TP53 7157 Affinity Capture-MS Homo sapiens 10 TOP2B 7155 Affinity Capture-MS Homo sapiens 11 HNF4A   Proximity Label-MS Homo sapiens 12 RPA2 6118 Proximity Label-MS Homo sapiens 13 JMJD6 23210 Two-hybrid Homo sapiens 14 DHX8 1659 Proximity Label-MS Homo sapiens 15 CUL3 8452 Affinity Capture-MS Homo sapiens 16 NHLRC2 374354 Affinity Capture-MS Homo sapiens 17 UBC 7316 Reconstituted Complex Homo sapiens Reconstituted Complex Homo sapiens 18 CALM1 801 Affinity Capture-MS Homo sapiens 19 OPLAH 26873 Two-hybrid Homo sapiens 20 PRPF40A 55660 Two-hybrid Homo sapiens 21 CREB1   Two-hybrid Homo sapiens 22 ZNF467   Two-hybrid Homo sapiens 23 BATF3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 24 Top2b 21974 Affinity Capture-MS Mus musculus 25 APOD 347 Affinity Capture-MS Homo sapiens 26 TOP2A 7153 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 27 CENPA   Proximity Label-MS Homo sapiens 28 HTT 3064 Two-hybrid Homo sapiens 29 CBX3 11335 Proximity Label-MS Homo sapiens 30 NUP50 10762 Proximity Label-MS Homo sapiens 31 UBE2I 7329 Two-hybrid Homo sapiens Two-hybrid Homo sapiens Biochemical Activity Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens 32 KDM1A 23028 Two-hybrid Homo sapiens 33 PIAS1 8554 Co-localization Homo sapiens Two-hybrid Homo sapiens 34 FXR2 9513 Two-hybrid Homo sapiens 35 KIF23 9493 Affinity Capture-MS Homo sapiens 36 PIAS2   Two-hybrid Homo sapiens 37 SUMO2 6613 Reconstituted Complex Homo sapiens 38 PCBD1 5092 Two-hybrid Homo sapiens 39 MUCL1   Affinity Capture-MS Homo sapiens 40 S100B 6285 Affinity Capture-MS Homo sapiens 41 PTGES3 10728 Affinity Capture-MS Homo sapiens 42 SUV39H1   Two-hybrid Homo sapiens 43 PML 5371 Affinity Capture-MS Homo sapiens 44 KLHL40   Two-hybrid Homo sapiens 45 AR 367 Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens 46 CALCOCO2   Two-hybrid Homo sapiens 47 LZTR1 8216 Two-hybrid Homo sapiens 48 SUMO1 7341 Reconstituted Complex Homo sapiens 49 DNAJB1 3337 Proximity Label-MS Homo sapiens 50 PRMT1 3276 Two-hybrid Homo sapiens 51 ZNF451 26036 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 52 PRMT8   Two-hybrid Homo sapiens 53 CPTP   Two-hybrid Homo sapiens 54 HERC2 8924 Affinity Capture-MS Homo sapiens 55 CDC5L 988 Two-hybrid Homo sapiens 56 ZBED1   Two-hybrid Homo sapiens View the network

Pathways in which ZNF451 is involved

No pathways found