Experiment description of studies that identified RAPGEF6 in sEVs

1 Experiment ID 224 MISEV standards ✔ EM|AFM Biophysical techniques ✔ Alix|TSG101|CD63|CD81 Enriched markers ✔ GOLGA2 Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25944692     Organism Homo sapiens Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S" Journal name Oncotarget Publication year 2015 Sample Neuroblastoma cells Sample name SH-SY5Y Isolation/purification methods Differential centrifugation Ultracentrifugation OptiPrep density gradient Flotation density 1.10 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting

Protein-protein interactions for RAPGEF6

Protein Interactor ExoCarta ID Identification method PubMed Species 1 YWHAH 7533 Affinity Capture-MS Homo sapiens 2 PARD3 56288 Proximity Label-MS Homo sapiens 3 FTL 2512 Affinity Capture-MS Homo sapiens 4 PHLPP1   Proximity Label-MS Homo sapiens 5 SNX27 81609 Affinity Capture-MS Homo sapiens 6 PLEKHA4 57664 Affinity Capture-MS Homo sapiens 7 BAG2 9532 Affinity Capture-MS Homo sapiens 8 GRN 2896 Affinity Capture-MS Homo sapiens 9 RAPGEF2 9693 Affinity Capture-MS Homo sapiens 10 NEDD4 4734 Reconstituted Complex Homo sapiens 11 OCLN 100506658 Proximity Label-MS Homo sapiens 12 WWP1 11059 Affinity Capture-MS Homo sapiens 13 XPO1 7514 Affinity Capture-MS Homo sapiens 14 YWHAB 7529 Affinity Capture-MS Homo sapiens 15 LINC00839   Protein-RNA Homo sapiens 16 PFN1 5216 Proximity Label-MS Homo sapiens 17 KRT8 3856 Proximity Label-MS Homo sapiens 18 SSSCA1 10534 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 19 APBA3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 20 RAP1A 5906 Biochemical Activity Homo sapiens 21 SHMT2 6472 Affinity Capture-RNA Homo sapiens 22 MAGEA9   Affinity Capture-MS Homo sapiens 23 DUSP16   Affinity Capture-MS Homo sapiens 24 MRAS 22808 Reconstituted Complex Homo sapiens 25 NXF1 10482 Affinity Capture-RNA Homo sapiens 26 APEX1 328 Affinity Capture-RNA Homo sapiens 27 RPA3 6119 Proximity Label-MS Homo sapiens 28 SOWAHB   Affinity Capture-MS Homo sapiens 29 MOV10 4343 Affinity Capture-RNA Homo sapiens 30 YWHAZ 7534 Affinity Capture-MS Homo sapiens 31 AURKA 6790 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 32 HSPA2 3306 Affinity Capture-MS Homo sapiens 33 GOLGA1   Proximity Label-MS Homo sapiens 34 SERPINB2 5055 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 35 HSPA1A 3303 Affinity Capture-MS Homo sapiens 36 RARRES1 5918 Affinity Capture-MS Homo sapiens 37 EPHA2 1969 Proximity Label-MS Homo sapiens 38 RPA4   Proximity Label-MS Homo sapiens 39 ENO1 2023 Affinity Capture-RNA Homo sapiens 40 KRAS 3845 Proximity Label-MS Homo sapiens 41 RHOB 388 Proximity Label-MS Homo sapiens 42 YWHAG 7532 Affinity Capture-MS Homo sapiens 43 YWHAE 7531 Affinity Capture-MS Homo sapiens 44 YAP1 10413 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 45 CAV1 857 Proximity Label-MS Homo sapiens 46 PIPSL 266971 Affinity Capture-MS Homo sapiens 47 RAP2A 5911 Affinity Capture-MS Homo sapiens Biochemical Activity Homo sapiens View the network

Pathways in which RAPGEF6 is involved

No pathways found