Gene description for BAG2
Gene name BCL2-associated athanogene 2
Gene symbol BAG2
Other names/aliases BAG-2
dJ417I1.2
Species Homo sapiens
 Database cross references - BAG2
ExoCarta ExoCarta_9532
Vesiclepedia VP_9532
Entrez Gene 9532
HGNC 938
MIM 603882
UniProt O95816  
 BAG2 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
 Gene ontology annotations for BAG2
Molecular Function
    adenyl-nucleotide exchange factor activity GO:0000774 IBA
    adenyl-nucleotide exchange factor activity GO:0000774 IDA
    protein binding GO:0005515 IPI
    heat shock protein binding GO:0031072 IEA
    ubiquitin protein ligase binding GO:0031625 IEA
    identical protein binding GO:0042802 IPI
    transmembrane transporter binding GO:0044325 IPI
    tau protein binding GO:0048156 NAS
    protein-folding chaperone binding GO:0051087 IPI
Biological Process
    protein folding GO:0006457 TAS
    positive regulation of protein processing GO:0010954 IMP
    protein metabolic process GO:0019538 IDA
    negative regulation of protein ubiquitination GO:0031397 IDA
    negative regulation of protein ubiquitination GO:0031397 ISS
    negative regulation of protein binding GO:0032091 IDA
    positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436 ISS
    protein stabilization GO:0050821 IBA
    protein stabilization GO:0050821 IDA
    positive regulation of proteasomal protein catabolic process GO:1901800 ISS
    negative regulation of ubiquitin protein ligase activity GO:1904667 IDA
Subcellular Localization
    cytosol GO:0005829 TAS
    microtubule GO:0005874 ISS
    axon GO:0030424 ISS
    dendrite GO:0030425 ISS
    protein folding chaperone complex GO:0101031 IPI
    dendritic microtubule GO:1901588 ISS
 Experiment description of studies that identified BAG2 in sEVs
1
Experiment ID 489
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 407
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 405
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
15
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 417
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 411
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 488
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
21
Experiment ID 418
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 413
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 211
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
24
Experiment ID 212
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
25
Experiment ID 406
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 415
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
28
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
29
Experiment ID 408
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 409
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 416
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 410
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for BAG2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HDAC4  
Affinity Capture-MS Homo sapiens
2 NOTCH3 4854
Reconstituted Complex Homo sapiens
3 DGCR14  
Affinity Capture-MS Homo sapiens
4 DNAJC11 55735
Proximity Label-MS Homo sapiens
5 PRPF8 10594
Proximity Label-MS Homo sapiens
6 LLGL1 3996
Affinity Capture-MS Homo sapiens
7 WNK1 65125
Affinity Capture-MS Homo sapiens
8 MKS1 54903
Affinity Capture-MS Homo sapiens
9 ZNF703  
Affinity Capture-MS Homo sapiens
10 DNAJB2 3300
Affinity Capture-MS Homo sapiens
11 EBNA-LP  
Affinity Capture-Western
Co-purification
Affinity Capture-MS
Co-fractionation
12 GAK 2580
Affinity Capture-MS Homo sapiens
13 GTF2F1 2962
Affinity Capture-MS Homo sapiens
14 KIF20A 10112
Affinity Capture-MS Homo sapiens
15 BRD2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 UBC 7316
Affinity Capture-MS Homo sapiens
17 VPS13C 54832
Affinity Capture-MS Homo sapiens
18 EDC4 23644
Affinity Capture-MS Homo sapiens
19 ISG15 9636
Affinity Capture-MS Homo sapiens
20 EIF4E2  
Affinity Capture-MS Homo sapiens
21 SOX2  
Affinity Capture-MS Homo sapiens
22 WDR62  
Affinity Capture-MS Homo sapiens
23 HDAC3 8841
Affinity Capture-MS Homo sapiens
24 WDR76  
Affinity Capture-MS Homo sapiens
25 STRN 6801
Affinity Capture-MS Homo sapiens
26 KIF23 9493
Affinity Capture-MS Homo sapiens
27 PPP2R5D 5528
Affinity Capture-MS Homo sapiens
28 Tube1  
Affinity Capture-MS Mus musculus
29 PTPN23 25930
Affinity Capture-MS Homo sapiens
30 POU5F1  
Affinity Capture-MS Homo sapiens
31 KIAA1671  
Affinity Capture-MS Homo sapiens
32 PPEF1  
Affinity Capture-MS Homo sapiens
33 VPS13D 55187
Affinity Capture-MS Homo sapiens
34 BOD1L1 259282
Affinity Capture-MS Homo sapiens
35 DNAJB1 3337
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
36 TUBGCP6 85378
Affinity Capture-MS Homo sapiens
37 POLR2C 5432
Proximity Label-MS Homo sapiens
38 ZNF598 90850
Affinity Capture-MS Homo sapiens
39 SLU7  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
40 KIF14 9928
Affinity Capture-MS Homo sapiens
41 PPIP5K2 23262
Affinity Capture-MS Homo sapiens
42 CHMP4C 92421
Affinity Capture-MS Homo sapiens
43 MTCH2 23788
Proximity Label-MS Homo sapiens
44 HPS5 11234
Affinity Capture-MS Homo sapiens
45 DBNL 28988
Affinity Capture-MS Homo sapiens
46 MARCH7  
Affinity Capture-MS Homo sapiens
47 ECT2 1894
Affinity Capture-MS Homo sapiens
48 LUZP1 7798
Affinity Capture-MS Homo sapiens
49 MAPRE1 22919
Affinity Capture-MS Homo sapiens
50 DNAJB7  
Affinity Capture-MS Homo sapiens
51 OFD1 8481
Affinity Capture-MS Homo sapiens
52 DNAJB8  
Affinity Capture-MS Homo sapiens
53 OTUD1 220213
Affinity Capture-MS Homo sapiens
54 YAP1 10413
Affinity Capture-MS Homo sapiens
55 TYK2 7297
Affinity Capture-MS Homo sapiens
56 CKAP5 9793
Affinity Capture-MS Homo sapiens
57 GTF3C2  
Affinity Capture-MS Homo sapiens
58 ANAPC5 51433
Affinity Capture-MS Homo sapiens
59 NOS2  
Affinity Capture-MS Homo sapiens
60 ENO1 2023
Cross-Linking-MS (XL-MS) Homo sapiens
61 EXPH5  
Affinity Capture-MS Homo sapiens
62 DDX39B 7919
Affinity Capture-MS Homo sapiens
63 PICALM 8301
Affinity Capture-MS Homo sapiens
64 STAM 8027
Affinity Capture-MS Homo sapiens
65 ANLN 54443
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 TMF1 7110
Affinity Capture-MS Homo sapiens
67 PHLPP1  
Affinity Capture-MS Homo sapiens
68 MARCH3 115123
Affinity Capture-MS Homo sapiens
69 DNAJB14  
Affinity Capture-MS Homo sapiens
70 HSPA5 3309
Affinity Capture-MS Homo sapiens
71 PPP2R2B 5521
Affinity Capture-MS Homo sapiens
72 TTC26 79989
Affinity Capture-MS Homo sapiens
73 Atg2a  
Affinity Capture-MS Mus musculus
74 ARRDC4  
Affinity Capture-MS Homo sapiens
75 EPAS1  
Affinity Capture-MS Homo sapiens
76 TXNRD3  
Affinity Capture-MS Homo sapiens
77 PRKCZ 5590
Affinity Capture-MS Homo sapiens
78 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
79 BPTF 2186
Affinity Capture-MS Homo sapiens
80 TTF2 8458
Affinity Capture-MS Homo sapiens
81 FN1 2335
Affinity Capture-MS Homo sapiens
82 PI4K2B 55300
Affinity Capture-MS Homo sapiens
83 EYA3  
Affinity Capture-MS Homo sapiens
84 SPEN 23013
Affinity Capture-MS Homo sapiens
85 RPA3 6119
Affinity Capture-MS Homo sapiens
86 DLST 1743
Affinity Capture-MS Homo sapiens
87 PHC1  
Affinity Capture-MS Homo sapiens
88 HSPA1A 3303
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
89 TBL1X 6907
Affinity Capture-MS Homo sapiens
90 HSPA4 3308
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
91 SGTA 6449
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
92 ILK 3611
Affinity Capture-MS Homo sapiens
93 CSDE1 7812
Affinity Capture-MS Homo sapiens
94 CHD5 26038
Affinity Capture-MS Homo sapiens
95 NPHP4 261734
Affinity Capture-MS Homo sapiens
96 STIL  
Affinity Capture-MS Homo sapiens
97 HAUS3  
Affinity Capture-MS Homo sapiens
98 VASP 7408
Affinity Capture-MS Homo sapiens
99 STUB1 10273
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
100 RELA 5970
Affinity Capture-MS Homo sapiens
101 TP53BP2  
Affinity Capture-MS Homo sapiens
102 TUBGCP2 10844
Affinity Capture-MS Homo sapiens
103 Tubg1 103733
Affinity Capture-MS Mus musculus
104 BCAS2 10286
Affinity Capture-MS Homo sapiens
105 USP49 25862
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
106 WDR77 79084
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
107 SLC5A5 6528
Affinity Capture-MS Homo sapiens
108 URGCP 55665
Affinity Capture-MS Homo sapiens
109 SHROOM1 134549
Affinity Capture-MS Homo sapiens
110 FKBP15 23307
Affinity Capture-MS Homo sapiens
111 RBM25 58517
Affinity Capture-MS Homo sapiens
112 TUBGCP3 10426
Affinity Capture-MS Homo sapiens
113 TBL3 10607
Affinity Capture-MS Homo sapiens
114 HSP90AA1 3320
Affinity Capture-MS Homo sapiens
115 MEF2D  
Affinity Capture-MS Homo sapiens
116 PRAME  
Affinity Capture-MS Homo sapiens
117 C3orf38 285237
Affinity Capture-MS Homo sapiens
118 SUPT6H 6830
Affinity Capture-MS Homo sapiens
119 CLTA 1211
Affinity Capture-MS Homo sapiens
120 ACO2 50
Affinity Capture-MS Homo sapiens
121 ZNF503 84858
Affinity Capture-MS Homo sapiens
122 FLYWCH2  
Affinity Capture-MS Homo sapiens
123 SNW1 22938
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
124 CIZ1  
Affinity Capture-MS Homo sapiens
125 POLG  
Affinity Capture-MS Homo sapiens
126 PIK3C2A 5286
Affinity Capture-MS Homo sapiens
127 PSMC4 5704
Affinity Capture-MS Homo sapiens
128 AP5Z1 9907
Affinity Capture-MS Homo sapiens
129 PPP2R2D 55844
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
130 POC5  
Affinity Capture-MS Homo sapiens
131 EDRF1  
Affinity Capture-MS Homo sapiens
132 EIF4G3 8672
Affinity Capture-MS Homo sapiens
133 KIF16B 55614
Affinity Capture-MS Homo sapiens
134 NCOA6  
Affinity Capture-MS Homo sapiens
135 KLC2 64837
Affinity Capture-MS Homo sapiens
136 DPH2 1802
Affinity Capture-MS Homo sapiens
137 HMCES  
Affinity Capture-MS Homo sapiens
138 FBXO7 25793
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
139 AAK1 22848
Affinity Capture-MS Homo sapiens
140 TARDBP 23435
Affinity Capture-MS Homo sapiens
141 DAPK1 1612
Affinity Capture-MS Homo sapiens
142 RPA2 6118
Affinity Capture-MS Homo sapiens
143 ARFGAP2 84364
Affinity Capture-MS Homo sapiens
144 QKI 9444
Affinity Capture-MS Homo sapiens
145 TRIM33 51592
Affinity Capture-MS Homo sapiens
146 ASXL1  
Affinity Capture-MS Homo sapiens
147 DNAJB6 10049
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
148 LGALS3BP 3959
Affinity Capture-MS Homo sapiens
149 NCOR1  
Affinity Capture-MS Homo sapiens
150 B3GNT2 10678
Affinity Capture-MS Homo sapiens
151 SKA1  
Affinity Capture-MS Homo sapiens
152 DHX35  
Affinity Capture-MS Homo sapiens
153 TLN1 7094
Affinity Capture-MS Homo sapiens
154 BRWD3  
Affinity Capture-MS Homo sapiens
155 PHC3  
Affinity Capture-MS Homo sapiens
156 RRM2B 50484
Affinity Capture-MS Homo sapiens
157 NR2F2  
Affinity Capture-MS Homo sapiens
158 PRC1 9055
Affinity Capture-MS Homo sapiens
159 TBC1D23 55773
Affinity Capture-MS Homo sapiens
160 TNIK 23043
Affinity Capture-MS Homo sapiens
161 SRRM2 23524
Affinity Capture-MS Homo sapiens
162 RECQL4  
Affinity Capture-MS Homo sapiens
163 OBSL1 23363
Affinity Capture-MS Homo sapiens
164 C6orf106  
Affinity Capture-MS Homo sapiens
165 STIP1 10963
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
166 DNAJC7 7266
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
167 TOMM40 10452
Affinity Capture-MS Homo sapiens
168 WIZ 58525
Affinity Capture-MS Homo sapiens
169 PALLD 23022
Affinity Capture-MS Homo sapiens
170 AMBRA1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
171 SETD1A 9739
Affinity Capture-MS Homo sapiens
172 NPAS1  
Affinity Capture-MS Homo sapiens
173 DNAH2 146754
Affinity Capture-MS Homo sapiens
174 AMOT  
Affinity Capture-MS Homo sapiens
175 DLGAP5  
Affinity Capture-MS Homo sapiens
176 LMAN1 3998
Proximity Label-MS Homo sapiens
177 UBN2  
Affinity Capture-MS Homo sapiens
178 PPP5C 5536
Affinity Capture-MS Homo sapiens
179 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
180 NFRKB  
Affinity Capture-MS Homo sapiens
181 EIF2A 83939
Affinity Capture-MS Homo sapiens
182 PSMD14 10213
Affinity Capture-MS Homo sapiens
183 CBL 867
Affinity Capture-MS Homo sapiens
184 KDM4B  
Affinity Capture-MS Homo sapiens
185 TUBA1C 84790
Affinity Capture-MS Homo sapiens
186 CSTF3 1479
Affinity Capture-MS Homo sapiens
187 PPP1R13B  
Affinity Capture-MS Homo sapiens
188 RAD18  
Affinity Capture-MS Homo sapiens
189 DCAF10  
Affinity Capture-MS Homo sapiens
190 SLFN5 162394
Affinity Capture-MS Homo sapiens
191 PHACTR4 65979
Affinity Capture-MS Homo sapiens
192 KCTD3  
Affinity Capture-MS Homo sapiens
193 ZCCHC11 23318
Affinity Capture-MS Homo sapiens
194 Ksr1  
Affinity Capture-MS Mus musculus
195 CYLD  
Affinity Capture-MS Homo sapiens
196 ZNF609  
Affinity Capture-MS Homo sapiens
197 TPX2  
Affinity Capture-MS Homo sapiens
198 YEATS2  
Affinity Capture-MS Homo sapiens
199 R3HDM1  
Affinity Capture-MS Homo sapiens
200 RC3H2  
Affinity Capture-MS Homo sapiens
201 UBAP2 55833
Affinity Capture-MS Homo sapiens
202 VWA5B2  
Affinity Capture-MS Homo sapiens
203 TBCE 6905
Affinity Capture-MS Homo sapiens
204 C1orf52  
Affinity Capture-MS Homo sapiens
205 UBE2L6 9246
Affinity Capture-MS Homo sapiens
206 BRD8 10902
Affinity Capture-MS Homo sapiens
207 RICTOR 253260
Affinity Capture-MS Homo sapiens
208 4932438A13Rik  
Affinity Capture-MS Mus musculus
209 EGFR 1956
Affinity Capture-MS Homo sapiens
210 PTK2 5747
Affinity Capture-MS Homo sapiens
211 LAMB3 3914
Affinity Capture-MS Homo sapiens
212 RIPK4  
Affinity Capture-MS Homo sapiens
213 LIMD1 8994
Affinity Capture-MS Homo sapiens
214 C21orf59 56683
Affinity Capture-MS Homo sapiens
215 SCYL2 55681
Affinity Capture-MS Homo sapiens
216 KDM3B  
Affinity Capture-MS Homo sapiens
217 SMAP1 60682
Affinity Capture-MS Homo sapiens
218 HAUS5 23354
Affinity Capture-MS Homo sapiens
219 MYC  
Affinity Capture-MS Homo sapiens
220 FAM91A1 157769
Affinity Capture-MS Homo sapiens
221 CUL7 9820
Affinity Capture-MS Homo sapiens
222 SLC12A6 9990
Affinity Capture-MS Homo sapiens
223 HUWE1 10075
Affinity Capture-MS Homo sapiens
224 TACC3  
Affinity Capture-MS Homo sapiens
225 KIAA0100  
Affinity Capture-MS Homo sapiens
226 TRAF7  
Affinity Capture-MS Homo sapiens
227 MAP2K2 5605
Affinity Capture-MS Homo sapiens
228 RRM2 6241
Affinity Capture-MS Homo sapiens
229 ARFIP1 27236
Affinity Capture-MS Homo sapiens
230 ZNFX1 57169
Affinity Capture-MS Homo sapiens
231 TTC1 7265
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
232 PRKY  
Affinity Capture-MS Homo sapiens
233 CEP170P1  
Affinity Capture-MS Homo sapiens
234 TP53 7157
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
235 SLK 9748
Affinity Capture-MS Homo sapiens
236 VPS13B  
Affinity Capture-MS Homo sapiens
237 VWA9  
Affinity Capture-MS Homo sapiens
238 CCDC117  
Affinity Capture-MS Homo sapiens
239 OXSR1 9943
Affinity Capture-MS Homo sapiens
240 PPP2R2C 5522
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
241 QSER1  
Affinity Capture-MS Homo sapiens
242 LSS 4047
Affinity Capture-MS Homo sapiens
243 OTUB1 55611
Affinity Capture-MS Homo sapiens
244 PIWIL1  
Affinity Capture-MS Homo sapiens
245 POU2F1 5451
Affinity Capture-MS Homo sapiens
246 JAK3 3718
Affinity Capture-MS Homo sapiens
247 ZNF195  
Affinity Capture-MS Homo sapiens
248 BAG5 9529
Affinity Capture-MS Homo sapiens
249 QRICH1  
Affinity Capture-MS Homo sapiens
250 DNAJB4 11080
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
251 STXBP2 6813
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
252 PUM1 9698
Affinity Capture-MS Homo sapiens
253 BRD1 23774
Affinity Capture-MS Homo sapiens
254 SKA3  
Affinity Capture-MS Homo sapiens
255 KRAS 3845
Affinity Capture-MS Homo sapiens
256 Smn1 20595
Affinity Capture-MS Mus musculus
257 CPSF3 51692
Affinity Capture-MS Homo sapiens
258 C17orf59 54785
Proximity Label-MS Homo sapiens
259 MTMR6 9107
Affinity Capture-MS Homo sapiens
260 COPG2 26958
Cross-Linking-MS (XL-MS) Homo sapiens
261 UBE2H 7328
Affinity Capture-MS Homo sapiens
262 FOXC1  
Affinity Capture-MS Homo sapiens
263 GMNN  
Affinity Capture-MS Homo sapiens
264 SP1  
Affinity Capture-MS Homo sapiens
265 REL 5966
Affinity Capture-MS Homo sapiens
266 DNAJA4 55466
Affinity Capture-MS Homo sapiens
267 MED16 10025
Affinity Capture-MS Homo sapiens
268 BUB1B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
269 RPS6KB2  
Affinity Capture-MS Homo sapiens
270 HSF2  
Affinity Capture-MS Homo sapiens
271 CAPZB 832
Affinity Capture-MS Homo sapiens
272 MCM2 4171
Affinity Capture-MS Homo sapiens
273 RASAL2 9462
Affinity Capture-MS Homo sapiens
274 LIG1 3978
Affinity Capture-MS Homo sapiens
275 MDC1  
Affinity Capture-MS Homo sapiens
276 BRPF3  
Affinity Capture-MS Homo sapiens
277 SF3A2 8175
Affinity Capture-MS Homo sapiens
278 TFEB  
Affinity Capture-MS Homo sapiens
279 PLD2 5338
Affinity Capture-MS Homo sapiens
280 BCORL1  
Affinity Capture-MS Homo sapiens
281 ESPL1  
Affinity Capture-MS Homo sapiens
282 MAVS 57506
Affinity Capture-MS Homo sapiens
283 DPH1  
Affinity Capture-MS Homo sapiens
284 HSPA8 3312
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
285 FAS 355
Proximity Label-MS Homo sapiens
286 PALD1 27143
Affinity Capture-MS Homo sapiens
287 CXXC1  
Affinity Capture-MS Homo sapiens
288 DLD 1738
Affinity Capture-MS Homo sapiens
289 FOXA1  
Affinity Capture-MS Homo sapiens
290 EML4 27436
Affinity Capture-MS Homo sapiens
291 PPIH 10465
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
292 IRAK1  
Affinity Capture-MS Homo sapiens
293 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
294 MTO1  
Affinity Capture-MS Homo sapiens
295 TUBA1A 7846
Affinity Capture-MS Homo sapiens
296 RTF1 23168
Affinity Capture-MS Homo sapiens
297 DNAJC5 80331
Affinity Capture-MS Homo sapiens
298 NLRP5  
Affinity Capture-MS Homo sapiens
299 MAPT  
Affinity Capture-MS Homo sapiens
300 LRWD1  
Affinity Capture-MS Homo sapiens
301 CHMP4B 128866
Affinity Capture-MS Homo sapiens
302 BTF3 689
Affinity Capture-MS Homo sapiens
303 METTL21A  
Affinity Capture-MS Homo sapiens
304 ARNT 405
Affinity Capture-MS Homo sapiens
305 DNAJA1 3301
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
306 ARMC1 55156
Affinity Capture-MS Homo sapiens
307 KIF11 3832
Affinity Capture-MS Homo sapiens
308 NFYC 4802
Affinity Capture-MS Homo sapiens
309 SLAIN1 122060
Affinity Capture-MS Homo sapiens
310 CCZ1 51622
Affinity Capture-MS Homo sapiens
311 PHF12  
Affinity Capture-MS Homo sapiens
312 LATS2 26524
Proximity Label-MS Homo sapiens
313 HDAC5 10014
Affinity Capture-MS Homo sapiens
314 MFF 56947
Affinity Capture-MS Homo sapiens
315 SF3A3 10946
Affinity Capture-MS Homo sapiens
316 ENDOG  
Affinity Capture-MS Homo sapiens
317 ARHGAP17 55114
Affinity Capture-MS Homo sapiens
318 DISC1 27185
Two-hybrid Homo sapiens
319 CWF19L1 55280
Affinity Capture-MS Homo sapiens
320 EFNA4  
Affinity Capture-MS Homo sapiens
321 METTL14  
Affinity Capture-MS Homo sapiens
322 DNAJB12 54788
Affinity Capture-MS Homo sapiens
323 CSTF2T  
Affinity Capture-MS Homo sapiens
324 BAG2 9532
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
325 SMG8 55181
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
326 AHNAK 79026
Co-fractionation Homo sapiens
327 TAB2  
Affinity Capture-MS Homo sapiens
328 RPRD2  
Affinity Capture-MS Homo sapiens
329 SF1 7536
Affinity Capture-MS Homo sapiens
330 NR3C1 2908
Affinity Capture-MS Homo sapiens
331 YY1 7528
Affinity Capture-MS Homo sapiens
332 METTL21B  
Affinity Capture-MS Homo sapiens
333 PDPK1 5170
Affinity Capture-MS Homo sapiens
334 MAP3K7  
Affinity Capture-MS Homo sapiens
335 RBM33  
Affinity Capture-MS Homo sapiens
336 DNAJC18  
Affinity Capture-MS Homo sapiens
337 HDLBP 3069
Affinity Capture-MS Homo sapiens
338 MBNL3  
Affinity Capture-MS Homo sapiens
339 Kctd5  
Affinity Capture-MS Mus musculus
340 SIK2  
Affinity Capture-MS Homo sapiens
341 LRRC40 55631
Affinity Capture-MS Homo sapiens
342 CPSF3L 54973
Affinity Capture-MS Homo sapiens
343 ARAF 369
Affinity Capture-MS Homo sapiens
344 FOXK1 221937
Affinity Capture-MS Homo sapiens
345 AKAP1 8165
Affinity Capture-MS Homo sapiens
346 DNAJC6  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
347 HIF1A 3091
Affinity Capture-MS Homo sapiens
348 FNBP4  
Affinity Capture-MS Homo sapiens
349 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
350 FBXL6  
Affinity Capture-MS Homo sapiens
351 MKL2  
Affinity Capture-MS Homo sapiens
352 PRRC2C 23215
Affinity Capture-MS Homo sapiens
353 RPA1 6117
Affinity Capture-MS Homo sapiens
354 MEN1 4221
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
355 RNF214  
Affinity Capture-MS Homo sapiens
356 RPTOR 57521
Affinity Capture-MS Homo sapiens
357 SHFM1 7979
Affinity Capture-MS Homo sapiens
358 MLF2 8079
Affinity Capture-MS Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
359 PTBP3 9991
Affinity Capture-MS Homo sapiens
360 CREBBP  
Affinity Capture-MS Homo sapiens
361 EIF4ENIF1 56478
Affinity Capture-MS Homo sapiens
362 RAVER1 125950
Affinity Capture-MS Homo sapiens
363 UFL1 23376
Affinity Capture-MS Homo sapiens
364 SPG11 80208
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
365 MBNL1 4154
Affinity Capture-MS Homo sapiens
366 MED12  
Affinity Capture-MS Homo sapiens
367 LRRK2 120892
Reconstituted Complex Homo sapiens
368 DNAJC5B  
Affinity Capture-MS Homo sapiens
369 NEDD1 121441
Affinity Capture-MS Homo sapiens
370 TCF20  
Affinity Capture-MS Homo sapiens
371 CIT 11113
Affinity Capture-MS Homo sapiens
372 METTL3  
Affinity Capture-MS Homo sapiens
373 RPRD1B 58490
Affinity Capture-MS Homo sapiens
374 MARCH4  
Affinity Capture-MS Homo sapiens
375 RC3H1 149041
Affinity Capture-MS Homo sapiens
376 ATXN3 4287
Affinity Capture-MS Homo sapiens
377 TEP1 7011
Affinity Capture-MS Homo sapiens
378 ZNF318 24149
Affinity Capture-MS Homo sapiens
379 EP300 2033
Affinity Capture-MS Homo sapiens
380 HSPA2 3306
Affinity Capture-MS Homo sapiens
381 CRBN  
Affinity Capture-MS Homo sapiens
382 REC8  
Affinity Capture-MS Homo sapiens
383 C15orf39  
Affinity Capture-MS Homo sapiens
384 CEP170 9859
Affinity Capture-MS Homo sapiens
385 ARHGAP21 57584
Affinity Capture-MS Homo sapiens
386 OTUD5 55593
Affinity Capture-MS Homo sapiens
387 Myh3  
Affinity Capture-MS Mus musculus
388 ABL2  
Affinity Capture-MS Homo sapiens
389 LRRC20  
Cross-Linking-MS (XL-MS) Homo sapiens
390 NCOA2 10499
Affinity Capture-MS Homo sapiens
391 POT1  
Affinity Capture-MS Homo sapiens
392 BUB1  
Affinity Capture-MS Homo sapiens
393 MKL1 57591
Affinity Capture-MS Homo sapiens
394 PPIE 10450
Affinity Capture-MS Homo sapiens
395 UBE2M 9040
Affinity Capture-MS Homo sapiens
396 TRIM66  
Affinity Capture-MS Homo sapiens
397 IFT122 55764
Affinity Capture-MS Homo sapiens
398 TAB1 10454
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
399 KDM6A  
Affinity Capture-MS Homo sapiens
400 WDR83  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
401 SMAP2 64744
Affinity Capture-MS Homo sapiens
402 PEX1 5189
Affinity Capture-MS Homo sapiens
403 USP36  
Affinity Capture-MS Homo sapiens
404 KIAA1429 25962
Affinity Capture-MS Homo sapiens
405 SRP54 6729
Affinity Capture-MS Homo sapiens
406 IRF2BP1 26145
Affinity Capture-MS Homo sapiens
407 PPP1R12A 4659
Affinity Capture-MS Homo sapiens
408 VPS72  
Affinity Capture-MS Homo sapiens
409 TGFB1 7040
Affinity Capture-MS Homo sapiens
410 TBL1XR1 79718
Affinity Capture-MS Homo sapiens
411 CASC5  
Affinity Capture-MS Homo sapiens
412 RNF219  
Affinity Capture-MS Homo sapiens
413 IMPDH2 3615
Proximity Label-MS Homo sapiens
414 HGS 9146
Affinity Capture-MS Homo sapiens
415 ARHGEF10 9639
Affinity Capture-MS Homo sapiens
416 DNAJC16  
Affinity Capture-MS Homo sapiens
417 BRD4 23476
Affinity Capture-MS Homo sapiens
418 BCOR  
Affinity Capture-MS Homo sapiens
419 MYCN  
Affinity Capture-MS Homo sapiens
420 FBXW5  
Affinity Capture-MS Homo sapiens
421 E2F4  
Affinity Capture-MS Homo sapiens
422 POLD1 5424
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
423 RFX1  
Affinity Capture-MS Homo sapiens
424 CCAR2 57805
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
425 IRF2BPL 64207
Affinity Capture-MS Homo sapiens
426 ZFC3H1 196441
Cross-Linking-MS (XL-MS) Homo sapiens
427 OTUD4  
Affinity Capture-MS Homo sapiens
428 ANKHD1 54882
Affinity Capture-MS Homo sapiens
429 SP110  
Affinity Capture-MS Homo sapiens
430 VCP 7415
Affinity Capture-MS Homo sapiens
431 TRIM32 22954
Affinity Capture-MS Homo sapiens
432 TRIM11  
Affinity Capture-MS Homo sapiens
433 HJURP  
Affinity Capture-MS Homo sapiens
434 CRY2  
Affinity Capture-MS Homo sapiens
435 PML 5371
Affinity Capture-MS Homo sapiens
436 EIF4G2 1982
Affinity Capture-MS Homo sapiens
437 POLE  
Affinity Capture-MS Homo sapiens
438 DNAJB5  
Affinity Capture-MS Homo sapiens
439 KIAA1033 23325
Affinity Capture-MS Homo sapiens
440 ENAH 55740
Affinity Capture-MS Homo sapiens
441 DNAJB11 51726
Affinity Capture-MS Homo sapiens
442 RAVER2  
Affinity Capture-MS Homo sapiens
443 BAG3 9531
Affinity Capture-MS Homo sapiens
444 SNX1 6642
Affinity Capture-MS Homo sapiens
445 ASCC3 10973
Affinity Capture-MS Homo sapiens
446 GAPVD1 26130
Affinity Capture-MS Homo sapiens
447 FANCD2  
Affinity Capture-MS Homo sapiens
448 TLE2  
Affinity Capture-MS Homo sapiens
449 DOCK7 85440
Affinity Capture-MS Homo sapiens
450 ZNF143  
Affinity Capture-MS Homo sapiens
451 XAB2 56949
Affinity Capture-MS Homo sapiens
452 CKAP2  
Affinity Capture-MS Homo sapiens
453 ADNP 23394
Affinity Capture-MS Homo sapiens
454 GREB1 9687
Affinity Capture-MS Homo sapiens
455 ELAC2 60528
Affinity Capture-MS Homo sapiens
456 BCL3  
Affinity Capture-MS Homo sapiens
457 RBM27  
Affinity Capture-MS Homo sapiens
458 TBCD 6904
Affinity Capture-MS Homo sapiens
459 SF3A1 10291
Affinity Capture-MS Homo sapiens
460 AURKB 9212
Affinity Capture-MS Homo sapiens
461 MLF1  
Affinity Capture-MS Homo sapiens
462 MAPK6  
Affinity Capture-MS Homo sapiens
463 Get4  
Affinity Capture-MS Mus musculus
464 EPN1 29924
Affinity Capture-MS Homo sapiens
465 RREB1 6239
Affinity Capture-MS Homo sapiens
466 ESRP2 80004
Affinity Capture-MS Homo sapiens
467 MFN2 9927
Proximity Label-MS Homo sapiens
468 CLTC 1213
Affinity Capture-MS Homo sapiens
469 C11orf84  
Affinity Capture-MS Homo sapiens
470 NANOG  
Affinity Capture-MS Homo sapiens
471 BRD3 8019
Affinity Capture-MS Homo sapiens
472 DNAJC13 23317
Affinity Capture-MS Homo sapiens
473 PRR14L 253143
Affinity Capture-MS Homo sapiens
474 SHKBP1  
Affinity Capture-MS Homo sapiens
475 KCNH2  
Affinity Capture-MS Homo sapiens
476 SALL2  
Affinity Capture-MS Homo sapiens
477 PAPOLA 10914
Affinity Capture-MS Homo sapiens
478 SYAP1 94056
Affinity Capture-MS Homo sapiens
479 DOCK5 80005
Affinity Capture-MS Homo sapiens
480 TUBG1 7283
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
481 PPP1R13L 10848
Affinity Capture-MS Homo sapiens
482 DNAJA2 10294
Affinity Capture-MS Homo sapiens
483 PTPN18 26469
Affinity Capture-MS Homo sapiens
484 RPAP1  
Affinity Capture-MS Homo sapiens
485 HNRNPA2B1 3181
Affinity Capture-MS Homo sapiens
486 MAPRE2 10982
Affinity Capture-MS Homo sapiens
487 ARHGAP18 93663
Affinity Capture-MS Homo sapiens
488 TAF2  
Affinity Capture-MS Homo sapiens
489 CNOT3 4849
Affinity Capture-MS Homo sapiens
490 TLE4  
Affinity Capture-MS Homo sapiens
491 PDLIM5 10611
Affinity Capture-MS Homo sapiens
492 WNK3  
Affinity Capture-MS Homo sapiens
493 TANGO6 79613
Affinity Capture-MS Homo sapiens
494 STK33  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
495 HSF1  
Affinity Capture-MS Homo sapiens
496 PXN 5829
Proximity Label-MS Homo sapiens
497 PINK1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
498 XRCC6 2547
Affinity Capture-MS Homo sapiens
499 HIRA  
Affinity Capture-MS Homo sapiens
500 C9orf72  
Affinity Capture-MS Homo sapiens
501 ARHGAP35 2909
Affinity Capture-MS Homo sapiens
502 IRF2BP2  
Affinity Capture-MS Homo sapiens
503 RAPGEF6 51735
Affinity Capture-MS Homo sapiens
504 LIMK2 3985
Affinity Capture-MS Homo sapiens
505 WDHD1  
Affinity Capture-MS Homo sapiens
506 CDC5L 988
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here