Gene description for RPA1
Gene name replication protein A1, 70kDa
Gene symbol RPA1
Other names/aliases HSSB
MST075
REPA1
RF-A
RP-A
RPA70
Species Homo sapiens
 Database cross references - RPA1
ExoCarta ExoCarta_6117
Vesiclepedia VP_6117
Entrez Gene 6117
HGNC 10289
MIM 179835
UniProt P27694  
 RPA1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 36706192    
Embryonic kidney cells 36706192    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for RPA1
Molecular Function
    damaged DNA binding GO:0003684 IBA
    damaged DNA binding GO:0003684 IDA
    single-stranded DNA binding GO:0003697 IDA
    protein binding GO:0005515 IPI
    single-stranded telomeric DNA binding GO:0043047 IBA
    metal ion binding GO:0046872 IEA
    G-rich strand telomeric DNA binding GO:0098505 IDA
    G-rich strand telomeric DNA binding GO:0098505 IMP
    chromatin-protein adaptor activity GO:0140463 IDA
Biological Process
    telomere maintenance GO:0000723 IC
    telomere maintenance GO:0000723 IMP
    telomere maintenance GO:0000723 NAS
    double-strand break repair via homologous recombination GO:0000724 IBA
    double-strand break repair via homologous recombination GO:0000724 IMP
    double-strand break repair via homologous recombination GO:0000724 NAS
    DNA replication GO:0006260 IMP
    DNA replication GO:0006260 NAS
    DNA-templated DNA replication GO:0006261 TAS
    DNA unwinding involved in DNA replication GO:0006268 IBA
    DNA repair GO:0006281 IDA
    DNA repair GO:0006281 IMP
    base-excision repair GO:0006284 IDA
    nucleotide-excision repair GO:0006289 IBA
    nucleotide-excision repair GO:0006289 IMP
    nucleotide-excision repair GO:0006289 NAS
    mismatch repair GO:0006298 IMP
    DNA recombination GO:0006310 TAS
    chromatin organization GO:0006325 IEA
    DNA damage response GO:0006974 IMP
    telomere maintenance via telomerase GO:0007004 IBA
    protein localization to chromosome GO:0034502 IDA
    meiotic cell cycle GO:0051321 IBA
    protein localization to site of double-strand break GO:1990166 IDA
Subcellular Localization
    chromosome, telomeric region GO:0000781 HDA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    DNA replication factor A complex GO:0005662 IBA
    DNA replication factor A complex GO:0005662 IDA
    DNA replication factor A complex GO:0005662 IPI
    PML body GO:0016605 IDA
    PML body GO:0016605 IDA
    site of double-strand break GO:0035861 IDA
    site of DNA damage GO:0090734 IMP
 Experiment description of studies that identified RPA1 in sEVs
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 497
MISEV standards
Biophysical techniques
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 498
MISEV standards
EM
Biophysical techniques
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 1203
MISEV standards
EM
Biophysical techniques
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
12
Experiment ID 407
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
13
Experiment ID 419
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 419
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 420
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 420
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 1275
MISEV standards
Biophysical techniques
CD9|TSG101|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 1280
MISEV standards
Biophysical techniques
TSG101|CD9|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T - Fraction 5
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density 1.151 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 405
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 363
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 364
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 365
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 417
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 411
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
26
Experiment ID 418
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 418
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 413
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 211
MISEV standards
EM
Biophysical techniques
TSG101|Alix|EpCAM|TFRC
Enriched markers
cytochrome c|GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
30
Experiment ID 212
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|EpCAM|TFRC
Enriched markers
Cytochrome C|GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
31
Experiment ID 406
MISEV standards
EM
Biophysical techniques
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 415
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
33
Experiment ID 434
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
34
Experiment ID 435
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
35
Experiment ID 408
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 409
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
37
Experiment ID 416
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
38
Experiment ID 191
MISEV standards
Biophysical techniques
Alix|CD81|CD9
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
39
Experiment ID 410
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
40
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RPA1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SEC22B 9554
Affinity Capture-MS Homo sapiens
2 ITGB1 3688
Affinity Capture-MS Homo sapiens
3 ARHGEF2 9181
Affinity Capture-MS Homo sapiens
4 MACROD1 28992
Affinity Capture-MS Homo sapiens
5 TK1 7083
Two-hybrid Homo sapiens
6 PCF11 51585
Affinity Capture-MS Homo sapiens
7 PRPF8 10594
Affinity Capture-MS Homo sapiens
8 ARPC2 10109
Co-fractionation Homo sapiens
9 TOP2B 7155
Affinity Capture-MS Homo sapiens
10 TPM2 7169
Affinity Capture-MS Homo sapiens
11 ARPC4 10093
Co-fractionation Homo sapiens
12 NFATC1 4772
Affinity Capture-MS Homo sapiens
13 DDX17 10521
Affinity Capture-MS Homo sapiens
14 EN1  
Affinity Capture-MS Homo sapiens
15 BRCA1 672
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
16 CELF1 10658
Affinity Capture-MS Homo sapiens
17 MAP4 4134
Affinity Capture-MS Homo sapiens
18 SNRNP40 9410
Affinity Capture-MS Homo sapiens
19 UBC 7316
Affinity Capture-MS Homo sapiens
20 THOC7 80145
Affinity Capture-MS Homo sapiens
21 SCAF4 57466
Affinity Capture-MS Homo sapiens
22 INTS1 26173
Affinity Capture-MS Homo sapiens
23 PRPF40A 55660
Affinity Capture-MS Homo sapiens
24 TAF1  
Affinity Capture-Western Homo sapiens
25 SOX2  
Affinity Capture-MS Homo sapiens
26 CENPA  
Affinity Capture-MS Homo sapiens
27 APEX1 328
Affinity Capture-MS Homo sapiens
28 EFNA3  
Affinity Capture-MS Homo sapiens
29 CUL7 9820
Affinity Capture-MS Homo sapiens
30 DDX23 9416
Affinity Capture-MS Homo sapiens
31 WDR76  
Affinity Capture-MS Homo sapiens
32 CHAF1A  
Affinity Capture-Western Homo sapiens
33 ACTR3 10096
Co-fractionation Homo sapiens
34 SF3B1 23451
Affinity Capture-MS Homo sapiens
35 CALD1 800
Affinity Capture-MS Homo sapiens
36 CPSF7 79869
Affinity Capture-MS Homo sapiens
37 FBL 2091
Affinity Capture-MS Homo sapiens
38 SMC2 10592
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 RPS9 6203
Affinity Capture-MS Homo sapiens
40 ORC6  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
41 HERC2 8924
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
42 ZNF598 90850
Affinity Capture-MS Homo sapiens
43 LMAN2 10960
Affinity Capture-MS Homo sapiens
44 CHTF18 63922
Affinity Capture-MS Homo sapiens
45 KIF3A 11127
Affinity Capture-MS Homo sapiens
46 TFRC 7037
Affinity Capture-MS Homo sapiens
47 EEF1A1 1915
Affinity Capture-MS Homo sapiens
48 RBM14 10432
Affinity Capture-MS Homo sapiens
49 DYNLT1 6993
Co-fractionation Homo sapiens
50 KIF14 9928
Affinity Capture-MS Homo sapiens
51 POLA2  
Co-fractionation Homo sapiens
52 KLF16  
Affinity Capture-MS Homo sapiens
53 CHMP4C 92421
Affinity Capture-MS Homo sapiens
54 SRBD1  
Affinity Capture-MS Homo sapiens
55 TCOF1 6949
Affinity Capture-MS Homo sapiens
56 ANXA7 310
Two-hybrid Homo sapiens
57 UBE4B 10277
Co-fractionation Homo sapiens
58 SPTA1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
59 RNF4 6047
Affinity Capture-Western Homo sapiens
60 CAPZA1 829
Affinity Capture-MS Homo sapiens
61 RFC5 5985
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
62 RAB14 51552
Affinity Capture-MS Homo sapiens
63 MUTYH  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
64 RAD9A  
Affinity Capture-Western Homo sapiens
65 ARG1 383
Affinity Capture-MS Homo sapiens
66 RPL18A 6142
Affinity Capture-MS Homo sapiens
67 PABPC1 26986
Affinity Capture-MS Homo sapiens
68 FANCG 2189
Affinity Capture-Western Homo sapiens
69 YAP1 10413
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
70 MYH9 4627
Affinity Capture-MS Homo sapiens
71 TRIM21 6737
Affinity Capture-MS Homo sapiens
72 SLX4  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
73 RAD1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
74 NAA10 8260
Co-fractionation Homo sapiens
75 SYNCRIP 10492
Affinity Capture-MS Homo sapiens
76 FKBP15 23307
Affinity Capture-MS Homo sapiens
77 ASCC2 84164
Two-hybrid Homo sapiens
78 RFC4 5984
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
79 PAK2 5062
Co-fractionation Homo sapiens
80 DYNLT3 6990
Co-fractionation Homo sapiens
81 HSPA5 3309
Affinity Capture-MS Homo sapiens
82 RBM39 9584
Affinity Capture-MS Homo sapiens
83 LMNB1 4001
Co-fractionation Homo sapiens
84 BKRF4  
Affinity Capture-MS
85 LMO7 4008
Affinity Capture-MS Homo sapiens
86 POLD3  
Co-fractionation Homo sapiens
87 ANXA1 301
Two-hybrid Homo sapiens
88 BCAP31 10134
Affinity Capture-MS Homo sapiens
89 ACTBL2 345651
Affinity Capture-MS Homo sapiens
90 ATRIP  
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
91 SSH3 54961
Co-fractionation Homo sapiens
92 EPRS 2058
Affinity Capture-MS Homo sapiens
93 EIF2S2 8894
Affinity Capture-MS Homo sapiens
94 FN1 2335
Affinity Capture-MS Homo sapiens
95 NTHL1  
Affinity Capture-MS Homo sapiens
96 TUBA4A 7277
Affinity Capture-MS Homo sapiens
97 FANCA  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
98 RPA3 6119
Co-purification Homo sapiens
Proximity Label-MS Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
99 ATP6V0D1 9114
Affinity Capture-MS Homo sapiens
100 AP2A2 161
Affinity Capture-MS Homo sapiens
101 OBSCN 84033
Affinity Capture-MS Homo sapiens
102 RFWD3  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
103 ANKS1A 23294
Co-fractionation Homo sapiens
104 DDX1 1653
Affinity Capture-MS Homo sapiens
105 NFATC2  
Affinity Capture-MS Homo sapiens
106 PRKDC 5591
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
107 U2SURP 23350
Affinity Capture-MS Homo sapiens
108 DDX46 9879
Affinity Capture-MS Homo sapiens
109 TLX1  
Affinity Capture-MS Homo sapiens
110 NUDT21 11051
Affinity Capture-MS Homo sapiens
111 BCAS2 10286
Affinity Capture-MS Homo sapiens
112 DTX3L 151636
Affinity Capture-MS Homo sapiens
113 CSNK1A1L 122011
Affinity Capture-MS Homo sapiens
114 POLR1B 84172
Affinity Capture-MS Homo sapiens
115 RBM25 58517
Affinity Capture-MS Homo sapiens
116 RUVBL2 10856
Affinity Capture-MS Homo sapiens
117 TCERG1 10915
Affinity Capture-MS Homo sapiens
118 CDK1 983
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Co-fractionation Homo sapiens
119 PSMB7 5695
Co-fractionation Homo sapiens
120 POLE3  
Co-fractionation Homo sapiens
121 MORF4L2  
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
122 FYCO1 79443
Affinity Capture-MS Homo sapiens
123 RMI1  
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
124 SIRT1  
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
125 RAB11FIP1 80223
Co-fractionation Homo sapiens
126 SSBP1 6742
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
127 DYNC1H1 1778
Co-fractionation Homo sapiens
128 SMC3 9126
Affinity Capture-MS Homo sapiens
129 ERCC6  
Affinity Capture-Western Homo sapiens
130 DROSHA  
Affinity Capture-MS Homo sapiens
131 NCL 4691
Affinity Capture-MS Homo sapiens
132 HNRNPL 3191
Affinity Capture-MS Homo sapiens
133 RAB13 5872
Affinity Capture-MS Homo sapiens
134 KAT2B  
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
135 POLA1  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
136 CEBPB  
Co-fractionation Homo sapiens
137 INTS3 65123
Affinity Capture-MS Homo sapiens
138 SNW1 22938
Affinity Capture-MS Homo sapiens
139 RAB5C 5878
Affinity Capture-MS Homo sapiens
140 ANXA2 302
Affinity Capture-MS Homo sapiens
141 SCAMP3 10067
Affinity Capture-MS Homo sapiens
142 RTEL1 51750
Affinity Capture-MS Homo sapiens
143 POLD2 5425
Co-fractionation Homo sapiens
144 EXOSC8  
Affinity Capture-MS Homo sapiens
145 DERL1 79139
Affinity Capture-MS Homo sapiens
146 HNRNPH1 3187
Affinity Capture-MS Homo sapiens
147 ATR  
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
148 PDHA1 5160
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
149 LDHA 3939
Affinity Capture-MS Homo sapiens
150 MCM3 4172
Affinity Capture-MS Homo sapiens
151 ORC2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
152 EXOSC7 23016
Affinity Capture-MS Homo sapiens
153 SPRTN  
Co-localization Homo sapiens
154 WDR3  
Affinity Capture-MS Homo sapiens
155 HSPA6 3310
Two-hybrid Homo sapiens
156 KCTD10 83892
Affinity Capture-MS Homo sapiens
157 SH3GL1 6455
Co-fractionation Homo sapiens
158 TARDBP 23435
Affinity Capture-MS Homo sapiens
159 RPA2 6118
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
160 MYO1F 4542
Affinity Capture-MS Homo sapiens
161 AP2A1 160
Affinity Capture-MS Homo sapiens
162 XPA  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
163 ZFR 51663
Affinity Capture-MS Homo sapiens
164 COPA 1314
Affinity Capture-MS Homo sapiens
165 YTHDF2 51441
Affinity Capture-MS Homo sapiens
166 PSIP1 11168
Affinity Capture-MS Homo sapiens
167 XRCC1 7515
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
168 RBM15 64783
Affinity Capture-MS Homo sapiens
169 RBM3 5935
Affinity Capture-MS Homo sapiens
170 CPSF1 29894
Affinity Capture-MS Homo sapiens
171 PRC1 9055
Affinity Capture-MS Homo sapiens
172 NPM1 4869
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
173 KHDRBS1 10657
Affinity Capture-MS Homo sapiens
174 CLINT1 9685
Affinity Capture-MS Homo sapiens
175 CDK7 1022
Affinity Capture-MS Homo sapiens
176 TIAL1 7073
Affinity Capture-MS Homo sapiens
177 CUL1 8454
Affinity Capture-MS Homo sapiens
178 AKTIP  
Two-hybrid Homo sapiens
179 USP7 7874
Affinity Capture-MS Homo sapiens
180 FGFR1 2260
Affinity Capture-MS Homo sapiens
181 DHX36 170506
Affinity Capture-MS Homo sapiens
182 RPL10L 140801
Affinity Capture-MS Homo sapiens
183 MED4 29079
Affinity Capture-MS Homo sapiens
184 GTF2I 2969
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
185 ACTA2 59
Affinity Capture-MS Homo sapiens
186 SYMPK 8189
Affinity Capture-MS Homo sapiens
187 HNRNPA0 10949
Affinity Capture-MS Homo sapiens
188 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
189 TOP3B 8940
Affinity Capture-MS Homo sapiens
190 RAI14 26064
Affinity Capture-MS Homo sapiens
191 NBN 4683
Affinity Capture-MS Homo sapiens
192 EXOC4 60412
Co-fractionation Homo sapiens
193 NTPCR 84284
Affinity Capture-MS Homo sapiens
194 SNRNP200 23020
Affinity Capture-MS Homo sapiens
195 CCNB1 891
Biochemical Activity Homo sapiens
Co-fractionation Homo sapiens
196 TUBA1C 84790
Affinity Capture-MS Homo sapiens
197 RAD18  
Affinity Capture-MS Homo sapiens
198 PPP2CA 5515
Affinity Capture-MS Homo sapiens
199 GAPDH 2597
Affinity Capture-MS Homo sapiens
200 RFC2 5982
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
201 RPLP0 6175
Affinity Capture-MS Homo sapiens
202 RAD21 5885
Affinity Capture-MS Homo sapiens
203 WDR33 55339
Affinity Capture-MS Homo sapiens
204 C7orf50 84310
Affinity Capture-MS Homo sapiens
205 ZCCHC8 55596
Affinity Capture-MS Homo sapiens
206 TPX2  
Affinity Capture-MS Homo sapiens
207 HNRNPD 3184
Affinity Capture-MS Homo sapiens
208 PTPN11 5781
Co-fractionation Homo sapiens
209 TUBB 203068
Affinity Capture-MS Homo sapiens
210 HUS1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
211 NKX2-5  
Affinity Capture-MS Homo sapiens
212 CANX 821
Affinity Capture-MS Homo sapiens
213 FLNA 2316
Affinity Capture-MS Homo sapiens
214 TP53BP1 7158
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
215 KIN  
Co-fractionation Homo sapiens
216 CTSC 1075
Co-fractionation Homo sapiens
217 POLR2E 5434
Affinity Capture-MS Homo sapiens
218 RAD52  
FRET Homo sapiens
Reconstituted Complex Homo sapiens
219 POLK  
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
220 SETD2  
Co-localization Homo sapiens
221 MYO1E 4643
Affinity Capture-MS Homo sapiens
222 TUBB4B 10383
Affinity Capture-MS Homo sapiens
223 EGFR 1956
Negative Genetic Homo sapiens
Affinity Capture-MS Homo sapiens
224 FUS 2521
Affinity Capture-MS Homo sapiens
225 WAPAL  
Affinity Capture-MS Homo sapiens
226 RPRD1B 58490
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
227 TFCP2 7024
Affinity Capture-MS Homo sapiens
228 G6PD 2539
Co-fractionation Homo sapiens
229 MSH4  
Co-localization Homo sapiens
230 EFTUD2 9343
Affinity Capture-MS Homo sapiens
231 CDK2 1017
Biochemical Activity Homo sapiens
Co-fractionation Homo sapiens
232 DYNC1LI1 51143
Co-fractionation Homo sapiens
233 SELENBP1 8991
Two-hybrid Homo sapiens
234 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
235 NIPBL 25836
Affinity Capture-MS Homo sapiens
236 EEF1A2 1917
Affinity Capture-MS Homo sapiens
237 THOC1 9984
Affinity Capture-MS Homo sapiens
238 HNRNPAB 3182
Affinity Capture-MS Homo sapiens
239 DDB1 1642
Affinity Capture-MS Homo sapiens
240 CCNA1  
Biochemical Activity Homo sapiens
241 MPRIP 23164
Affinity Capture-MS Homo sapiens
242 COLGALT1 79709
Co-fractionation Homo sapiens
243 LMNA 4000
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
244 ADAR 103
Affinity Capture-MS Homo sapiens
245 PFDN5 5204
Co-fractionation Homo sapiens
246 DSP 1832
Affinity Capture-MS Homo sapiens
247 RPL19 6143
Affinity Capture-MS Homo sapiens
248 SPTBN1 6711
Affinity Capture-MS Homo sapiens
249 PRRC2A 7916
Affinity Capture-MS Homo sapiens
250 PARP1 142
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
251 ELMSAN1  
Affinity Capture-MS Homo sapiens
252 HDGF 3068
Affinity Capture-MS Homo sapiens
253 ATXN3 4287
Affinity Capture-MS Homo sapiens
254 H3F3A 3020
Affinity Capture-Western Homo sapiens
255 TP53 7157
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
256 EXOC8 149371
Co-fractionation Homo sapiens
257 PGRMC1 10857
Affinity Capture-MS Homo sapiens
258 CSNK1A1 1452
Affinity Capture-MS Homo sapiens
259 HDAC6 10013
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
260 AKAP8  
Affinity Capture-MS Homo sapiens
261 HLTF  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
262 PTBP1 5725
Affinity Capture-MS Homo sapiens
263 BID  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
264 ATG101  
Affinity Capture-MS Homo sapiens
265 CMTR1 23070
Co-fractionation Homo sapiens
266 MLH1 4292
Co-fractionation Homo sapiens
267 CAPRIN1 4076
Affinity Capture-MS Homo sapiens
268 BUB3 9184
Affinity Capture-MS Homo sapiens
269 RPS5 6193
Affinity Capture-MS Homo sapiens
270 HNRNPK 3190
Affinity Capture-MS Homo sapiens
271 YTHDF3  
Affinity Capture-MS Homo sapiens
272 RAD50 10111
Affinity Capture-MS Homo sapiens
273 ESR1  
Affinity Capture-MS Homo sapiens
274 RAB8A 4218
Affinity Capture-MS Homo sapiens
275 RBM23  
Two-hybrid Homo sapiens
276 TAGLN2 8407
Affinity Capture-MS Homo sapiens
277 PRDX1 5052
Affinity Capture-MS Homo sapiens
278 ALPP 250
Affinity Capture-MS Homo sapiens
279 SMAD3 4088
Two-hybrid Homo sapiens
280 HSPA4L 22824
Co-fractionation Homo sapiens
281 SMARCAL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
282 SH3KBP1 30011
Affinity Capture-MS Homo sapiens
283 GATA4  
Affinity Capture-MS Homo sapiens
284 CDKN2AIP  
Affinity Capture-MS Homo sapiens
285 TEX10 54881
Affinity Capture-MS Homo sapiens
286 RAB2A 5862
Affinity Capture-MS Homo sapiens
287 CPE 1363
Two-hybrid Homo sapiens
288 RALY 22913
Affinity Capture-MS Homo sapiens
289 XPC  
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
290 MCM7 4176
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
291 MPG 4350
Affinity Capture-MS Homo sapiens
292 RAB1A 5861
Affinity Capture-MS Homo sapiens
293 NAPA 8775
Affinity Capture-MS Homo sapiens
294 RPS6KA5 9252
Two-hybrid Homo sapiens
295 SP1  
Affinity Capture-MS Homo sapiens
296 LIMCH1 22998
Affinity Capture-MS Homo sapiens
297 LUZP4  
Affinity Capture-MS Homo sapiens
298 MRE11A 4361
Affinity Capture-MS Homo sapiens
299 XRN2 22803
Affinity Capture-MS Homo sapiens
300 HNRNPCL1 343069
Affinity Capture-MS Homo sapiens
301 FUBP3 8939
Affinity Capture-MS Homo sapiens
302 HNRNPR 10236
Affinity Capture-MS Homo sapiens
303 PPP1R10  
Affinity Capture-MS Homo sapiens
304 LTN1 26046
Co-fractionation Homo sapiens
305 RTN4 57142
Affinity Capture-MS Homo sapiens
306 ERCC5  
Co-fractionation Homo sapiens
307 CAPZB 832
Affinity Capture-MS Homo sapiens
308 RPAIN  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
309 PELP1 27043
Affinity Capture-MS Homo sapiens
310 TRIM28 10155
Affinity Capture-MS Homo sapiens
311 MCM2 4171
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
312 DAZAP1 26528
Affinity Capture-MS Homo sapiens
313 ZNF638 27332
Affinity Capture-MS Homo sapiens
314 LIG1 3978
Co-fractionation Homo sapiens
315 IQGAP1 8826
Affinity Capture-MS Homo sapiens
316 MDC1  
Affinity Capture-MS Homo sapiens
317 EWSR1 2130
Affinity Capture-MS Homo sapiens
318 MCM6 4175
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
319 RCC1 1104
Two-hybrid Homo sapiens
320 ATRX 546
Affinity Capture-MS Homo sapiens
321 CKAP5 9793
Affinity Capture-MS Homo sapiens
322 ATG16L1 55054
Affinity Capture-MS Homo sapiens
323 CLTC 1213
Affinity Capture-MS Homo sapiens
324 CALR 811
Co-fractionation Homo sapiens
325 PARP14 54625
Affinity Capture-MS Homo sapiens
326 CSNK2B 1460
Two-hybrid Homo sapiens
327 PABPC4 8761
Affinity Capture-MS Homo sapiens
328 USP37  
Proximity Label-MS Homo sapiens
329 KIAA0196 9897
Affinity Capture-MS Homo sapiens
330 HSPA8 3312
Affinity Capture-MS Homo sapiens
331 NF2 4771
Affinity Capture-MS Homo sapiens
332 NSUN2 54888
Co-fractionation Homo sapiens
333 DLD 1738
Affinity Capture-MS Homo sapiens
334 FANCM 57697
Affinity Capture-MS Homo sapiens
335 FOXC1  
Affinity Capture-MS Homo sapiens
336 RPL9 6133
Affinity Capture-MS Homo sapiens
337 CUL4B 8450
Co-fractionation Homo sapiens
338 PARK2  
Affinity Capture-MS Homo sapiens
339 PNKP 11284
Affinity Capture-MS Homo sapiens
340 TCEA2  
Two-hybrid Homo sapiens
341 XRN1 54464
Affinity Capture-MS Homo sapiens
342 BLM 641
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
343 DNTTIP1 116092
Affinity Capture-MS Homo sapiens
344 CAST 831
Co-fractionation Homo sapiens
345 PTPRE 5791
Affinity Capture-MS Homo sapiens
346 GTF2H1 2965
Affinity Capture-Western Homo sapiens
347 FUBP1 8880
Co-fractionation Homo sapiens
348 NTRK1 4914
Affinity Capture-MS Homo sapiens
349 ETAA1  
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
350 PPME1 51400
Co-fractionation Homo sapiens
351 RPA4  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Two-hybrid Homo sapiens
352 ACTB 60
Affinity Capture-MS Homo sapiens
353 COA7  
Co-fractionation Homo sapiens
354 DHX9 1660
Affinity Capture-MS Homo sapiens
355 MNAT1  
Affinity Capture-MS Homo sapiens
356 SLX4IP  
Affinity Capture-MS Homo sapiens
357 TMEM33 55161
Affinity Capture-MS Homo sapiens
358 HNRNPA3 220988
Affinity Capture-MS Homo sapiens
359 OXR1  
Co-fractionation Homo sapiens
360 PDS5A 23244
Affinity Capture-MS Homo sapiens
361 PURB 5814
Affinity Capture-MS Homo sapiens
362 RBM10  
Affinity Capture-MS Homo sapiens
363 HNRNPDL 9987
Affinity Capture-MS Homo sapiens
364 SF3B2 10992
Affinity Capture-MS Homo sapiens
365 EFNA4  
Affinity Capture-MS Homo sapiens
366 CCNA2 890
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
367 RAB6A 5870
Affinity Capture-MS Homo sapiens
368 MSH2 4436
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
369 BAG2 9532
Affinity Capture-MS Homo sapiens
370 SMARCA5 8467
Affinity Capture-MS Homo sapiens
371 EXOSC10 5394
Affinity Capture-MS Homo sapiens
372 AHNAK 79026
Affinity Capture-MS Homo sapiens
373 RPRD2  
Affinity Capture-MS Homo sapiens
374 PTEN 5728
Affinity Capture-MS Homo sapiens
375 DCAF13 25879
Affinity Capture-MS Homo sapiens
376 GTF3C2  
Affinity Capture-MS Homo sapiens
377 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
378 ERCC1  
FRET Homo sapiens
379 HNRNPUL1 11100
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
380 POLR2A 5430
Affinity Capture-Western Homo sapiens
381 RFC1 5981
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
382 PRPF19 27339
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
383 FDPS 2224
Co-fractionation Homo sapiens
384 RAB11B 9230
Affinity Capture-MS Homo sapiens
385 TOP1 7150
Co-fractionation Homo sapiens
386 SKIV2L2 23517
Affinity Capture-MS Homo sapiens
387 MATR3 9782
Affinity Capture-MS Homo sapiens
388 RPL18 6141
Affinity Capture-MS Homo sapiens
389 DIDO1  
Affinity Capture-MS Homo sapiens
390 RNF2  
Affinity Capture-MS Homo sapiens
391 SEH1L 81929
Affinity Capture-MS Homo sapiens
392 HAX1  
Two-hybrid Homo sapiens
393 PUS1 80324
Co-fractionation Homo sapiens
394 TSR1 55720
Affinity Capture-MS Homo sapiens
395 ILF3 3609
Affinity Capture-MS Homo sapiens
396 XRCC5 7520
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
397 SMS 6611
Co-fractionation Homo sapiens
398 PROSC 11212
Affinity Capture-MS Homo sapiens
399 EIF2S1 1965
Affinity Capture-MS Homo sapiens
400 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
401 LIG3 3980
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
402 TOPBP1 11073
Co-localization Homo sapiens
403 RPL6 6128
Affinity Capture-MS Homo sapiens
404 RAB10 10890
Affinity Capture-MS Homo sapiens
405 DDX3X 1654
Affinity Capture-MS Homo sapiens
406 DNA2  
Affinity Capture-MS Homo sapiens
407 RPA1 6117
Co-crystal Structure Homo sapiens
Co-crystal Structure Homo sapiens
408 ALDH1B1 219
Co-fractionation Homo sapiens
409 EFNA1  
Affinity Capture-MS Homo sapiens
410 HNRNPM 4670
Affinity Capture-MS Homo sapiens
411 PARP9 83666
Affinity Capture-MS Homo sapiens
412 SHFM1 7979
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
413 HSPB1 3315
Affinity Capture-MS Homo sapiens
414 GRPEL1 80273
Co-fractionation Homo sapiens
415 CHD1L 9557
Affinity Capture-MS Homo sapiens
416 THOC6 79228
Affinity Capture-MS Homo sapiens
417 MTHFD1 4522
Affinity Capture-MS Homo sapiens
418 ERGIC1 57222
Affinity Capture-MS Homo sapiens
419 TRIM25 7706
Affinity Capture-MS Homo sapiens
420 RAVER1 125950
Affinity Capture-MS Homo sapiens
421 PCNA 5111
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
422 Samm50  
Affinity Capture-MS Mus musculus
423 KDM1A 23028
Affinity Capture-MS Homo sapiens
424 SERPINB12 89777
Affinity Capture-MS Homo sapiens
425 RAB7A 7879
Affinity Capture-MS Homo sapiens
426 RPS7 6201
Affinity Capture-MS Homo sapiens
427 HNRNPF 3185
Affinity Capture-MS Homo sapiens
428 C14orf166 51637
Affinity Capture-MS Homo sapiens
429 SERBP1 26135
Affinity Capture-MS Homo sapiens
430 UBA6 55236
Co-fractionation Homo sapiens
431 VIM 7431
Two-hybrid Homo sapiens
432 TFAM 7019
Co-fractionation Homo sapiens
433 CAV1 857
Affinity Capture-MS Homo sapiens
434 UBE2H 7328
Affinity Capture-MS Homo sapiens
435 SLFN11 91607
Affinity Capture-MS Homo sapiens
436 PRIM2 5558
Co-fractionation Homo sapiens
437 ACTR2 10097
Co-fractionation Homo sapiens
438 RAB6B 51560
Affinity Capture-MS Homo sapiens
439 AP2B1 163
Affinity Capture-MS Homo sapiens
440 CCNH  
Affinity Capture-MS Homo sapiens
441 PAXIP1  
Two-hybrid Homo sapiens
442 RPS3A 6189
Affinity Capture-MS Homo sapiens
443 CAPZA2 830
Co-fractionation Homo sapiens
444 YTHDF1 54915
Affinity Capture-MS Homo sapiens
445 LOC442497 442497
Affinity Capture-MS Homo sapiens
446 RPL13A 23521
Affinity Capture-MS Homo sapiens
447 THOC2 57187
Affinity Capture-MS Homo sapiens
448 RPL15 6138
Affinity Capture-MS Homo sapiens
449 HGH1 51236
Two-hybrid Homo sapiens
450 ELAVL1 1994
Affinity Capture-MS Homo sapiens
451 MSH3 4437
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
452 TMPO 7112
Affinity Capture-MS Homo sapiens
453 ILF2 3608
Affinity Capture-MS Homo sapiens
454 PPP1CC 5501
Affinity Capture-MS Homo sapiens
455 TOP2A 7153
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
456 RPS20 6224
Co-fractionation Homo sapiens
457 PPP1R12A 4659
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
458 BTF3 689
Affinity Capture-MS Homo sapiens
459 RFC3 5983
Affinity Capture-MS Homo sapiens
460 ANP32B 10541
Co-fractionation Homo sapiens
461 IMPDH2 3615
Affinity Capture-MS Homo sapiens
462 POLL  
Affinity Capture-MS Homo sapiens
463 PRIM1  
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
464 FBXO18 84893
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
465 MTUS2 23281
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
466 RAD51  
Reconstituted Complex Homo sapiens
467 MYO1B 4430
Affinity Capture-MS Homo sapiens
468 INTS6 26512
Affinity Capture-MS Homo sapiens
469 AARSD1 80755
Co-fractionation Homo sapiens
470 ADD1 118
Affinity Capture-MS Homo sapiens
471 RAB35 11021
Affinity Capture-MS Homo sapiens
472 CHERP 10523
Affinity Capture-MS Homo sapiens
473 TRIP12 9320
Affinity Capture-MS Homo sapiens
474 SMC4 10051
Affinity Capture-MS Homo sapiens
475 WRN 7486
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
476 EDC4 23644
Affinity Capture-MS Homo sapiens
477 PRPF6 24148
Affinity Capture-MS Homo sapiens
478 STRA13  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
479 POLD1 5424
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
480 BRIP1  
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Far Western Homo sapiens
Reconstituted Complex Homo sapiens
481 PSMD4 5710
Affinity Capture-Western Homo sapiens
482 RB1CC1 9821
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
483 CCAR2 57805
Affinity Capture-MS Homo sapiens
484 RBM4 5936
Affinity Capture-MS Homo sapiens
485 NONO 4841
Affinity Capture-MS Homo sapiens
486 STAU1 6780
Co-fractionation Homo sapiens
487 GNB5 10681
Two-hybrid Homo sapiens
488 BZLF1  
Affinity Capture-MS
Affinity Capture-Western
489 GRAMD4 23151
Affinity Capture-MS Homo sapiens
490 DDX5 1655
Affinity Capture-MS Homo sapiens
491 IFI16 3428
Affinity Capture-MS Homo sapiens
492 AP1B1 162
Affinity Capture-MS Homo sapiens
493 SRF  
Affinity Capture-MS Homo sapiens
494 TERF2  
Affinity Capture-MS Homo sapiens
495 SMC1A 8243
Affinity Capture-MS Homo sapiens
496 MYH10 4628
Affinity Capture-MS Homo sapiens
497 MYH11 4629
Affinity Capture-MS Homo sapiens
498 POLE  
Co-fractionation Homo sapiens
499 KIAA1033 23325
Affinity Capture-MS Homo sapiens
500 CEBPA  
Proximity Label-MS Homo sapiens
Protein-peptide Homo sapiens
501 EYA1  
Affinity Capture-MS Homo sapiens
502 C17orf53  
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
Reconstituted Complex Homo sapiens
503 SMARCC2 6601
Affinity Capture-MS Homo sapiens
504 RNASEH1 246243
Affinity Capture-MS Homo sapiens
505 NEURL4  
Affinity Capture-MS Homo sapiens
506 WDR82 80335
Affinity Capture-MS Homo sapiens
507 STK10 6793
Co-fractionation Homo sapiens
508 LIMA1 51474
Affinity Capture-MS Homo sapiens
509 NUMA1 4926
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
510 SFPQ 6421
Affinity Capture-MS Homo sapiens
511 EXO5  
Reconstituted Complex Homo sapiens
512 TAF15 8148
Affinity Capture-MS Homo sapiens
513 HIST1H3A 8350
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
514 FANCD2  
Affinity Capture-MS Homo sapiens
515 HELQ  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
516 SNRPB 6628
Affinity Capture-MS Homo sapiens
517 PLRG1 5356
Co-fractionation Homo sapiens
518 CTNNB1 1499
Affinity Capture-MS Homo sapiens
519 PARP12 64761
Affinity Capture-MS Homo sapiens
520 HCFC1 3054
Affinity Capture-MS Homo sapiens
521 NAA15 80155
Co-fractionation Homo sapiens
522 UNG  
Affinity Capture-MS Homo sapiens
523 CTTN 2017
Affinity Capture-MS Homo sapiens
524 TOP3A  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
525 MCM4 4173
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
526 RBM27  
Affinity Capture-MS Homo sapiens
527 BBX 56987
Affinity Capture-MS Homo sapiens
528 RPL7 6129
Affinity Capture-MS Homo sapiens
529 SF3A1 10291
Affinity Capture-MS Homo sapiens
530 AURKB 9212
Affinity Capture-MS Homo sapiens
531 RPL13P12  
Affinity Capture-MS Homo sapiens
532 RBM26 64062
Affinity Capture-MS Homo sapiens
533 FBXO6 26270
Affinity Capture-MS Homo sapiens
534 ZUFSP 221302
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
535 MYOF 26509
Affinity Capture-MS Homo sapiens
536 MSI2 124540
Affinity Capture-MS Homo sapiens
537 DNAJC9 23234
Affinity Capture-MS Homo sapiens
538 KCNAB2 8514
Affinity Capture-MS Homo sapiens
539 ESRP2 80004
Affinity Capture-MS Homo sapiens
540 DYRK2 8445
Affinity Capture-MS Homo sapiens
541 SF3B3 23450
Affinity Capture-MS Homo sapiens
542 KRAS 3845
Negative Genetic Homo sapiens
543 CORO1C 23603
Co-fractionation Homo sapiens
544 UBXN1 51035
Co-fractionation Homo sapiens
545 CCDC8  
Affinity Capture-MS Homo sapiens
546 PKP3 11187
Affinity Capture-MS Homo sapiens
547 DHX15 1665
Affinity Capture-MS Homo sapiens
548 MYO1C 4641
Affinity Capture-MS Homo sapiens
549 ARRB2 409
Affinity Capture-MS Homo sapiens
550 SPTAN1 6709
Affinity Capture-MS Homo sapiens
551 BKRF1  
Affinity Capture-Western
552 KAT2A  
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
553 RPS7P4  
Affinity Capture-MS Homo sapiens
554 HNRNPA2B1 3181
Affinity Capture-MS Homo sapiens
555 DGCR8  
Affinity Capture-MS Homo sapiens
556 SMNDC1  
Co-fractionation Homo sapiens
557 PDHB 5162
Co-fractionation Homo sapiens
558 CHD4 1108
Affinity Capture-MS Homo sapiens
559 COBL  
Affinity Capture-MS Homo sapiens
560 GEMIN4 50628
Affinity Capture-MS Homo sapiens
561 ANXA2P2 304
Affinity Capture-MS Homo sapiens
562 RBFOX2 23543
Affinity Capture-MS Homo sapiens
563 MCPH1  
Co-localization Homo sapiens
564 APITD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
565 MOV10 4343
Affinity Capture-MS Homo sapiens
566 GTF2H3  
Affinity Capture-MS Homo sapiens
567 TRIP4 9325
Affinity Capture-MS Homo sapiens
568 RAD23B 5887
Reconstituted Complex Homo sapiens
569 RPS8 6202
Affinity Capture-MS Homo sapiens
570 GEMIN5 25929
Affinity Capture-MS Homo sapiens
571 XRCC6 2547
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
572 HIRA  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
573 HNRNPU 3192
Affinity Capture-MS Homo sapiens
574 C9orf72  
Affinity Capture-MS Homo sapiens
575 EMG1 10436
Affinity Capture-MS Homo sapiens
576 STRBP 55342
Affinity Capture-MS Homo sapiens
577 ESYT1 23344
Affinity Capture-MS Homo sapiens
578 WDHD1  
Affinity Capture-MS Homo sapiens
579 TIPIN  
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
580 CDC5L 988
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
581 CNDP2 55748
Co-fractionation Homo sapiens
View the network image/svg+xml
 Pathways in which RPA1 is involved
PathwayEvidenceSource
Activation of ATR in response to replication stress TAS Reactome
Activation of the pre-replicative complex TAS Reactome
Base Excision Repair TAS Reactome
Cell Cycle IEA Reactome
Cell Cycle TAS Reactome
Cell Cycle Checkpoints TAS Reactome
Cell Cycle, Mitotic TAS Reactome
Cellular response to heat stress TAS Reactome
Cellular responses to stimuli TAS Reactome
Cellular responses to stress TAS Reactome
Chromosome Maintenance TAS Reactome
Defective homologous recombination repair (HRR) due to BRCA2 loss of function TAS Reactome
Disease TAS Reactome
Diseases of DNA Double-Strand Break Repair TAS Reactome
Diseases of DNA repair TAS Reactome
DNA Damage Bypass TAS Reactome
DNA Double-Strand Break Repair TAS Reactome
DNA Repair TAS Reactome
DNA Repair IEA Reactome
DNA Replication TAS Reactome
DNA Replication Pre-Initiation TAS Reactome
DNA strand elongation TAS Reactome
Dual Incision in GG-NER TAS Reactome
Dual incision in TC-NER TAS Reactome
Extension of Telomeres TAS Reactome
Fanconi Anemia Pathway TAS Reactome
Formation of Incision Complex in GG-NER TAS Reactome
G1/S Transition TAS Reactome
G2/M Checkpoints TAS Reactome
G2/M DNA damage checkpoint TAS Reactome
Gap-filling DNA repair synthesis and ligation in GG-NER TAS Reactome
Gap-filling DNA repair synthesis and ligation in TC-NER TAS Reactome
Gene expression (Transcription) TAS Reactome
Generic Transcription Pathway TAS Reactome
Global Genome Nucleotide Excision Repair (GG-NER) TAS Reactome
HDR through Homologous Recombination (HRR) TAS Reactome
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) TAS Reactome
HDR through Single Strand Annealing (SSA) TAS Reactome
Homologous DNA Pairing and Strand Exchange TAS Reactome
Homology Directed Repair TAS Reactome
HSF1 activation TAS Reactome
Impaired BRCA2 binding to RAD51 TAS Reactome
Lagging Strand Synthesis TAS Reactome
Meiosis IEA Reactome
Meiotic recombination IEA Reactome
Metabolism of proteins TAS Reactome
Mismatch Repair TAS Reactome
Mismatch Repair IEA Reactome
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) TAS Reactome
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) IEA Reactome
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) TAS Reactome
Mitotic G1 phase and G1/S transition TAS Reactome
Nucleotide Excision Repair TAS Reactome
PCNA-Dependent Long Patch Base Excision Repair TAS Reactome
Post-translational protein modification TAS Reactome
Presynaptic phase of homologous DNA pairing and strand exchange TAS Reactome
Processing of DNA double-strand break ends TAS Reactome
Processive synthesis on the C-strand of the telomere TAS Reactome
Processive synthesis on the lagging strand TAS Reactome
Recognition of DNA damage by PCNA-containing replication complex TAS Reactome
Regulation of HSF1-mediated heat shock response TAS Reactome
Regulation of TP53 Activity TAS Reactome
Regulation of TP53 Activity through Phosphorylation TAS Reactome
Removal of the Flap Intermediate TAS Reactome
Removal of the Flap Intermediate from the C-strand TAS Reactome
Reproduction IEA Reactome
Resolution of Abasic Sites (AP sites) TAS Reactome
Resolution of AP sites via the multiple-nucleotide patch replacement pathway TAS Reactome
RNA Polymerase II Transcription TAS Reactome
S Phase TAS Reactome
SUMO E3 ligases SUMOylate target proteins TAS Reactome
SUMOylation TAS Reactome
SUMOylation of DNA damage response and repair proteins TAS Reactome
Synthesis of DNA TAS Reactome
Telomere C-strand (Lagging Strand) Synthesis TAS Reactome
Telomere Maintenance TAS Reactome
Termination of translesion DNA synthesis TAS Reactome
Transcription-Coupled Nucleotide Excision Repair (TC-NER) TAS Reactome
Transcriptional Regulation by TP53 TAS Reactome
Translesion Synthesis by POLH TAS Reactome
Translesion synthesis by POLI TAS Reactome
Translesion synthesis by POLK TAS Reactome
Translesion synthesis by REV1 TAS Reactome
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template TAS Reactome





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