Gene description for CAV1
Gene name caveolin 1, caveolae protein, 22kDa
Gene symbol CAV1
Other names/aliases BSCL3
CGL3
LCCNS
MSTP085
PPH3
VIP21
Species Homo sapiens
 Database cross references - CAV1
ExoCarta ExoCarta_857
Vesiclepedia VP_857
Entrez Gene 857
HGNC 1527
MIM 601047
UniProt Q03135  
 CAV1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34796683    
Breast cancer cells 34796683    
Chondrocytes 35931686    
Chondrocytes 35931686    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Melanoma cells 19801663    
Melanoma cells 19381331    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells Unpublished / Not applicable
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Plasma 19381331    
Pluripotent stem cells 34108659    
Prostate cancer cells 25519911    
Prostate cancer cells 25519911    
Prostate cancer cells 25519911    
Prostate cancer cells 25844599    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
 Gene ontology annotations for CAV1
Molecular Function
    signaling receptor binding GO:0005102 IPI
    patched binding GO:0005113 NAS
    protein binding GO:0005515 IPI
    oxysterol binding GO:0008142 ISS
    cholesterol binding GO:0015485 TAS
    peptidase activator activity GO:0016504 ISS
    enzyme binding GO:0019899 IPI
    protein kinase binding GO:0019901 IBA
    protein kinase binding GO:0019901 IPI
    protein tyrosine kinase inhibitor activity GO:0030292 IMP
    protein tyrosine kinase inhibitor activity GO:0030292 ISS
    protein-macromolecule adaptor activity GO:0030674 IEA
    small GTPase binding GO:0031267 IPI
    identical protein binding GO:0042802 IPI
    transmembrane transporter binding GO:0044325 IBA
    transmembrane transporter binding GO:0044325 IPI
    protein-containing complex binding GO:0044877 IPI
    protein heterodimerization activity GO:0046982 IEA
    nitric-oxide synthase binding GO:0050998 IPI
    ATPase binding GO:0051117 IPI
    ATPase binding GO:0051117 ISS
    molecular adaptor activity GO:0060090 IBA
    molecular adaptor activity GO:0060090 TAS
    inward rectifier potassium channel inhibitor activity GO:0070320 IDA
    protein sequestering activity GO:0140311 ISS
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 ISS
    MAPK cascade GO:0000165 IEA
    angiogenesis GO:0001525 IEA
    vasculogenesis GO:0001570 ISS
    response to hypoxia GO:0001666 ISS
    endothelial cell proliferation GO:0001935 IEA
    negative regulation of endothelial cell proliferation GO:0001937 IBA
    negative regulation of endothelial cell proliferation GO:0001937 ISS
    negative regulation of cytokine-mediated signaling pathway GO:0001960 IEA
    glandular epithelial cell differentiation GO:0002067 IEA
    response to ischemia GO:0002931 IEA
    regulation of the force of heart contraction by chemical signal GO:0003057 IEA
    triglyceride metabolic process GO:0006641 ISS
    nitric oxide biosynthetic process GO:0006809 IEA
    calcium ion transport GO:0006816 ISS
    intracellular calcium ion homeostasis GO:0006874 ISS
    regulation of smooth muscle contraction GO:0006940 ISS
    skeletal muscle tissue development GO:0007519 ISS
    lactation GO:0007595 IEA
    protein localization GO:0008104 ISS
    cellular response to starvation GO:0009267 IEP
    response to bacterium GO:0009617 IDA
    positive regulation of calcium ion transport into cytosol GO:0010524 ISS
    post-transcriptional regulation of gene expression GO:0010608 IEA
    positive regulation of gene expression GO:0010628 IEA
    positive regulation of cholesterol efflux GO:0010875 IDA
    protein transport GO:0015031 IEA
    vesicle organization GO:0016050 ISS
    receptor-mediated endocytosis of virus by host cell GO:0019065 IGI
    regulation of fatty acid metabolic process GO:0019217 ISS
    cytokine-mediated signaling pathway GO:0019221 IEA
    lipid storage GO:0019915 ISS
    cell differentiation GO:0030154 IBA
    regulation of blood coagulation GO:0030193 IMP
    cholesterol transport GO:0030301 TAS
    positive regulation of cell migration GO:0030335 IMP
    negative regulation of BMP signaling pathway GO:0030514 IDA
    negative regulation of epithelial cell differentiation GO:0030857 ISS
    mammary gland development GO:0030879 ISS
    T cell costimulation GO:0031295 IDA
    negative regulation of protein ubiquitination GO:0031397 IMP
    positive regulation of protein ubiquitination GO:0031398 IMP
    receptor internalization GO:0031623 IDA
    receptor internalization GO:0031623 IMP
    maintenance of protein location in cell GO:0032507 ISS
    response to progesterone GO:0032570 IDA
    negative regulation of peptidyl-serine phosphorylation GO:0033137 IDA
    positive regulation of peptidyl-serine phosphorylation GO:0033138 IDA
    intracellular nitric oxide homeostasis GO:0033484 ISS
    positive regulation of toll-like receptor 3 signaling pathway GO:0034141 IMP
    insulin receptor internalization GO:0038016 IEA
    angiotensin-activated signaling pathway GO:0038166 ISS
    vasoconstriction GO:0042310 IEA
    cholesterol homeostasis GO:0042632 ISS
    cholesterol homeostasis GO:0042632 TAS
    positive regulation of canonical NF-kappaB signal transduction GO:0043123 IMP
    negative regulation of MAPK cascade GO:0043409 ISS
    response to estrogen GO:0043627 IDA
    protein localization to plasma membrane raft GO:0044860 ISS
    negative regulation of nitric oxide biosynthetic process GO:0045019 ISS
    positive regulation of vasoconstriction GO:0045907 ISS
    negative regulation of receptor signaling pathway via JAK-STAT GO:0046426 ISS
    muscle cell cellular homeostasis GO:0046716 IEA
    fibroblast proliferation GO:0048144 IEA
    negative regulation of fibroblast proliferation GO:0048147 IEA
    negative regulation of pinocytosis GO:0048550 IMP
    regulation of cytosolic calcium ion concentration GO:0051480 IBA
    regulation of cytosolic calcium ion concentration GO:0051480 IDA
    response to calcium ion GO:0051592 ISS
    establishment of localization in cell GO:0051649 IEA
    membrane depolarization GO:0051899 ISS
    calcium ion homeostasis GO:0055074 ISS
    mammary gland involution GO:0060056 ISS
    canonical Wnt signaling pathway GO:0060070 IDA
    positive regulation of cell adhesion molecule production GO:0060355 IMP
    negative regulation of necroptotic process GO:0060546 IEA
    caveola assembly GO:0070836 IBA
    caveola assembly GO:0070836 IGI
    caveola assembly GO:0070836 IMP
    caveola assembly GO:0070836 ISS
    cellular response to misfolded protein GO:0071218 IMP
    cellular response to exogenous dsRNA GO:0071360 IMP
    cellular response to peptide hormone stimulus GO:0071375 ISS
    cellular response to hyperoxia GO:0071455 IMP
    cellular response to transforming growth factor beta stimulus GO:0071560 IEA
    basement membrane organization GO:0071711 IEA
    caveolin-mediated endocytosis GO:0072584 IDA
    regulation of heart rate by cardiac conduction GO:0086091 ISS
    negative regulation of canonical Wnt signaling pathway GO:0090090 ISS
    apoptotic signaling pathway GO:0097190 IMP
    regulation of membrane repolarization during action potential GO:0098903 IMP
    regulation of cardiac muscle cell action potential involved in regulation of contraction GO:0098909 IC
    regulation of ventricular cardiac muscle cell action potential GO:0098911 ISS
    positive regulation of cold-induced thermogenesis GO:0120162 ISS
    regulation of ruffle assembly GO:1900027 IDA
    negative regulation of potassium ion transmembrane transport GO:1901380 IMP
    regulation of cell communication by electrical coupling involved in cardiac conduction GO:1901844 ISS
    protein localization to basolateral plasma membrane GO:1903361 ISS
    positive regulation of gap junction assembly GO:1903598 ISS
    negative regulation of inward rectifier potassium channel activity GO:1903609 IMP
    positive regulation of ERAD pathway GO:1904294 IMP
    regulation of entry of bacterium into host cell GO:2000535 IDA
    negative regulation of anoikis GO:2000811 IMP
    positive regulation of extrinsic apoptotic signaling pathway GO:2001238 IMP
    positive regulation of intrinsic apoptotic signaling pathway GO:2001244 IMP
Subcellular Localization
    Golgi membrane GO:0000139 IDA
    Golgi membrane GO:0000139 TAS
    acrosomal membrane GO:0002080 IEA
    caveolar macromolecular signaling complex GO:0002095 IEA
    endosome GO:0005768 IDA
    endoplasmic reticulum GO:0005783 IDA
    endoplasmic reticulum membrane GO:0005789 TAS
    Golgi apparatus GO:0005794 IBA
    lipid droplet GO:0005811 TAS
    plasma membrane GO:0005886 IDA
    plasma membrane GO:0005886 TAS
    caveola GO:0005901 IDA
    caveola GO:0005901 NAS
    focal adhesion GO:0005925 HDA
    focal adhesion GO:0005925 IBA
    focal adhesion GO:0005925 IDA
    cilium GO:0005929 IEA
    cell cortex GO:0005938 IEA
    membrane GO:0016020 IDA
    basolateral plasma membrane GO:0016323 IDA
    apical plasma membrane GO:0016324 IDA
    endocytic vesicle membrane GO:0030666 TAS
    cytoplasmic vesicle GO:0031410 IBA
    cytoplasmic vesicle GO:0031410 IDA
    early endosome membrane GO:0031901 TAS
    protein-containing complex GO:0032991 IDA
    sarcolemma GO:0042383 IBA
    membrane raft GO:0045121 IDA
    membrane raft GO:0045121 ISS
    perinuclear region of cytoplasm GO:0048471 IBA
    perinuclear region of cytoplasm GO:0048471 IDA
    perinuclear region of cytoplasm GO:0048471 ISS
 Experiment description of studies that identified CAV1 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 1331
MISEV standards
Biophysical techniques
✔
CD9|CD151|CD63|ICAM1|Alix
Enriched markers
✘ Negative markers
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 34796683    
Organism Homo sapiens
Experiment description High TSPAN8 expression in epithelial cancer cell-derived small extracellular vesicles promote confined diffusion and pronounced uptake
Authors "Wang T, Wang X, Wang H, Li L, Zhang C, Xiang R, Tan X, Li Z, Jiang C, Zheng L, Xiao L, Yue S."
Journal name J Extracell Vesicles
Publication year 2021
Sample Breast cancer cells
Sample name T-47D
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
10
Experiment ID 1332
MISEV standards
Biophysical techniques
✔
CD9|CD151|CD63|ICAM1|Alix
Enriched markers
✘ Negative markers
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 34796683    
Organism Homo sapiens
Experiment description High TSPAN8 expression in epithelial cancer cell-derived small extracellular vesicles promote confined diffusion and pronounced uptake
Authors "Wang T, Wang X, Wang H, Li L, Zhang C, Xiang R, Tan X, Li Z, Jiang C, Zheng L, Xiao L, Yue S."
Journal name J Extracell Vesicles
Publication year 2021
Sample Breast cancer cells
Sample name T-47D
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
11
Experiment ID 494
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Osteoarthritic cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
12
Experiment ID 496
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Healthy cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
13
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
14
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
18
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
RT-PCR
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
23
Experiment ID 236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
RT-PCR
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
24
Experiment ID 236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
Western blotting
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
25
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 72
MISEV standards
✘ Biophysical techniques
✔
LAMP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 19801663    
Organism Homo sapiens
Experiment description Microenvironmental pH is a key factor for exosome traffic in tumor cells.
Authors "Parolini I, Federici C, Raggi C, Lugini L, Palleschi S, de Milito A, Coscia C, Iessi E, Logozzi MA, Molinari A, Colone M, Tatti M, Sargiacomo M, Fais S"
Journal name JBC
Publication year 2009
Sample Melanoma cells
Sample name Me665/1
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Thin layer chromatography
28
Experiment ID 74
MISEV standards
✘ Biophysical techniques
✔
RAB5B|LAMP1|CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 19381331    
Organism Homo sapiens
Experiment description High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients.
Authors "Logozzi M, De Milito A, Lugini L, Borghi M, Calabrò L, Spada M, Perdicchio M, Marino ML, Federici C, Iessi E, Brambilla D, Venturi G, Lozupone F, Santinami M, Huber V, Maio M, Rivoltini L, Fais S"
Journal name PLoS One
Publication year 2009
Sample Melanoma cells
Sample name Me501
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
ELISA
FACS
29
Experiment ID 257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
30
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
31
Experiment ID 260
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 1205Lu
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
32
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
33
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
34
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
37
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
38
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
39
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
40
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
41
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
42
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
43
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
44
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
45
Experiment ID 75
MISEV standards
✘ Biophysical techniques
✔
RAB5B|CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 19381331    
Organism Homo sapiens
Experiment description High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients.
Authors "Logozzi M, De Milito A, Lugini L, Borghi M, Calabrò L, Spada M, Perdicchio M, Marino ML, Federici C, Iessi E, Brambilla D, Venturi G, Lozupone F, Santinami M, Huber V, Maio M, Rivoltini L, Fais S"
Journal name PLoS One
Publication year 2009
Sample Plasma
Sample name Plasma - Melanoma
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
ELISA
FACS
46
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
47
Experiment ID 245
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|CD9|CD63|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25519911    
Organism Homo sapiens
Experiment description The ether lipid precursor hexadecylglycerol stimulates the release and changes the composition of exosomes derived from PC-3 cells
Authors "Phuyal S, Skotland T, Hessvik NP, Simolin H, Overbye A, Brech A, Parton RG, Ekroos K, Sandvig K, Llorente A."
Journal name J Biol Chem
Publication year 2015
Sample Prostate cancer cells
Sample name PC-3 - Ethanol treated (control)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Lipids
Protein
Methods used in the study Western blotting
Mass spectrometry
48
Experiment ID 246
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|CD9|CD63|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25519911    
Organism Homo sapiens
Experiment description The ether lipid precursor hexadecylglycerol stimulates the release and changes the composition of exosomes derived from PC-3 cells
Authors "Phuyal S, Skotland T, Hessvik NP, Simolin H, Overbye A, Brech A, Parton RG, Ekroos K, Sandvig K, Llorente A."
Journal name J Biol Chem
Publication year 2015
Sample Prostate cancer cells
Sample name PC-3 - sn-1-O-hexadecylglycerol treated
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Lipids
Methods used in the study Western blotting
Mass spectrometry
49
Experiment ID 247
MISEV standards
✘ Biophysical techniques
✔
TSG101|Alix|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25519911    
Organism Homo sapiens
Experiment description The ether lipid precursor hexadecylglycerol stimulates the release and changes the composition of exosomes derived from PC-3 cells
Authors "Phuyal S, Skotland T, Hessvik NP, Simolin H, Overbye A, Brech A, Parton RG, Ekroos K, Sandvig K, Llorente A."
Journal name J Biol Chem
Publication year 2015
Sample Prostate cancer cells
Sample name PC-3 - DL- palmitin treated
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Lipids
Methods used in the study Western blotting
Mass spectrometry
50
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
51
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
52
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
53
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
54
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for CAV1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ITGB1 3688
Proximity Label-MS Homo sapiens
2 TAS2R19  
Affinity Capture-MS Homo sapiens
3 GJD3  
Proximity Label-MS Homo sapiens
4 ISG15 9636
Affinity Capture-MS Homo sapiens
5 WDR6 11180
Proximity Label-MS Homo sapiens
6 UTRN 7402
Proximity Label-MS Homo sapiens
7 PPP2R4 5524
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
8 SLC1A5 6510
Proximity Label-MS Homo sapiens
9 EPB41L1 2036
Proximity Label-MS Homo sapiens
10 MSRB2  
Affinity Capture-MS Homo sapiens
11 LLGL1 3996
Proximity Label-MS Homo sapiens
12 DAG1 1605
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
13 SH3BP4 23677
Proximity Label-MS Homo sapiens
14 CEP55 55165
Proximity Label-MS Homo sapiens
15 JPH1 56704
Proximity Label-MS Homo sapiens
16 TMEM184A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 SH3RF1  
Proximity Label-MS Homo sapiens
18 KIF20A 10112
Affinity Capture-MS Homo sapiens
19 MAP4K4 9448
Proximity Label-MS Homo sapiens
20 EDNRB 1910
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
21 ADCY5  
Affinity Capture-Western Homo sapiens
22 ARHGAP1 392
Proximity Label-MS Homo sapiens
23 LPCAT1 79888
Proximity Label-MS Homo sapiens
24 SEPT9 10801
Affinity Capture-MS Homo sapiens
25 PTRH2 51651
Proximity Label-MS Homo sapiens
26 MON2 23041
Proximity Label-MS Homo sapiens
27 NDRG1 10397
Proximity Label-MS Homo sapiens
28 APBB2  
Proximity Label-MS Homo sapiens
29 ADCY6 112
Affinity Capture-Western Homo sapiens
30 UNC5B 219699
Proximity Label-MS Homo sapiens
31 STOM 2040
Proximity Label-MS Homo sapiens
32 SRC 6714
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
33 PSMD12 5718
Proximity Label-MS Homo sapiens
34 YIPF3 25844
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 KDR  
Co-fractionation Homo sapiens
36 RASAL2 9462
Proximity Label-MS Homo sapiens
37 RHOA 387
Reconstituted Complex Homo sapiens
38 Flot2 14252
Affinity Capture-MS Mus musculus
39 DYNLL1 8655
Affinity Capture-MS Homo sapiens
40 CD99 4267
Proximity Label-MS Homo sapiens
41 MARCKSL1 65108
Proximity Label-MS Homo sapiens
42 MLXIPL  
Affinity Capture-MS Homo sapiens
43 SLC6A15 55117
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
44 ZFYVE9  
Proximity Label-MS Homo sapiens
45 TFRC 7037
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
46 STX12 23673
Proximity Label-MS Homo sapiens
47 TMEM87A 25963
Proximity Label-MS Homo sapiens
48 YES1 7525
Proximity Label-MS Homo sapiens
49 EXOC3 11336
Proximity Label-MS Homo sapiens
50 EXOC4 60412
Proximity Label-MS Homo sapiens
51 NOTCH2 4853
Proximity Label-MS Homo sapiens
52 RABGEF1 27342
Affinity Capture-MS Homo sapiens
53 TOLLIP 54472
Affinity Capture-Western Homo sapiens
54 PKP2 5318
Proximity Label-MS Homo sapiens
55 PDGFRB 5159
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
56 MCAM 4162
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
57 EFR3B  
Proximity Label-MS Homo sapiens
58 PDXDC1 23042
Proximity Label-MS Homo sapiens
59 FYN 2534
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
60 GORASP2 26003
Proximity Label-MS Homo sapiens
61 NOS2  
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
62 GJB1 2705
Affinity Capture-Western Homo sapiens
63 Coro1c 23790
Affinity Capture-MS Mus musculus
64 MPP7 143098
Proximity Label-MS Homo sapiens
65 DLC1 10395
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
66 FLOT2 2319
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
67 ANKRD13A 88455
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
68 IQGAP2 10788
Proximity Label-MS Homo sapiens
69 EPHB4 2050
Proximity Label-MS Homo sapiens
70 STAM 8027
Proximity Label-MS Homo sapiens
71 LRP8 7804
Proximity Label-MS Homo sapiens
72 ZDHHC20 253832
Proximity Label-MS Homo sapiens
73 ANLN 54443
Affinity Capture-MS Homo sapiens
74 TMF1 7110
Proximity Label-MS Homo sapiens
75 DST 667
Proximity Label-MS Homo sapiens
76 CSNK1G3 1456
Proximity Label-MS Homo sapiens
77 PALM2  
Proximity Label-MS Homo sapiens
78 GJB2  
Affinity Capture-Western Homo sapiens
79 PLAA 9373
Affinity Capture-Western Homo sapiens
80 ARHGAP32  
Proximity Label-MS Homo sapiens
81 FAM83B  
Proximity Label-MS Homo sapiens
82 FAM129B 64855
Proximity Label-MS Homo sapiens
83 Cd2ap 12488
Affinity Capture-MS Mus musculus
84 AHCYL1 10768
Proximity Label-MS Homo sapiens
85 CDCA3 83461
Proximity Label-MS Homo sapiens
86 ROBO1 6091
Proximity Label-MS Homo sapiens
87 ERBB2IP 55914
Proximity Label-MS Homo sapiens
88 ADCY3 109
Proximity Label-MS Homo sapiens
89 DLG1 1739
Proximity Label-MS Homo sapiens
90 GOLT1B 51026
Affinity Capture-MS Homo sapiens
91 TNFRSF1A 7132
Co-fractionation Homo sapiens
92 CUL3 8452
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
93 MBOAT1  
Affinity Capture-MS Homo sapiens
94 ITGA1 3672
Proximity Label-MS Homo sapiens
95 UBA2 10054
Proximity Label-MS Homo sapiens
96 RPA3 6119
Affinity Capture-MS Homo sapiens
97 IGSF3 3321
Proximity Label-MS Homo sapiens
98 ABCC1 4363
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
99 MPZL1 9019
Proximity Label-MS Homo sapiens
100 DZIP1  
Proximity Label-MS Homo sapiens
101 MARVELD2 153562
Proximity Label-MS Homo sapiens
102 CTNNA1 1495
Proximity Label-MS Homo sapiens
103 KIDINS220 57498
Proximity Label-MS Homo sapiens
104 EFNB2 1948
Proximity Label-MS Homo sapiens
105 Tsg101 22088
Affinity Capture-MS Mus musculus
106 CDC42EP4  
Proximity Label-MS Homo sapiens
107 KCNA5  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
108 GOLGB1 2804
Proximity Label-MS Homo sapiens
109 SLC4A2 6522
Proximity Label-MS Homo sapiens
110 FLVCR1 28982
Proximity Label-MS Homo sapiens
111 GRK5 2869
Reconstituted Complex Homo sapiens
112 GPRIN3  
Proximity Label-MS Homo sapiens
113 PSD3 23362
Proximity Label-MS Homo sapiens
114 BSDC1 55108
Proximity Label-MS Homo sapiens
115 TGFBR2 7048
Affinity Capture-Western Homo sapiens
116 RAB11FIP5 26056
Proximity Label-MS Homo sapiens
117 SCYL3 57147
Proximity Label-MS Homo sapiens
118 MACF1 23499
Proximity Label-MS Homo sapiens
119 WWOX 51741
Proximity Label-MS Homo sapiens
120 SPTBN2 6712
Proximity Label-MS Homo sapiens
121 APRT 353
Proximity Label-MS Homo sapiens
122 HSP90AA1 3320
Affinity Capture-Western Homo sapiens
123 TRIP11 9321
Proximity Label-MS Homo sapiens
124 ANKRD26 22852
Proximity Label-MS Homo sapiens
125 RAB11FIP1 80223
Proximity Label-MS Homo sapiens
126 LATS1  
Protein-peptide Homo sapiens
Proximity Label-MS Homo sapiens
127 ITGA2 3673
Proximity Label-MS Homo sapiens
128 RABL3 285282
Affinity Capture-MS Homo sapiens
129 FAM219A 203259
Proximity Label-MS Homo sapiens
130 RAB2A 5862
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
131 PHACTR4 65979
Proximity Label-MS Homo sapiens
132 GOLGA5 9950
Proximity Label-MS Homo sapiens
133 SLC25A51  
Proximity Label-MS Homo sapiens
134 RAB11A 8766
Proximity Label-MS Homo sapiens
135 EPHA2 1969
Proximity Label-MS Homo sapiens
136 RAB5C 5878
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
137 SCP2 6342
Affinity Capture-Western Homo sapiens
FRET Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
138 PRAF2 11230
Proximity Label-MS Homo sapiens
139 VANGL1 81839
Proximity Label-MS Homo sapiens
140 SNX29  
Proximity Label-MS Homo sapiens
141 KCNA3  
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
FRET Homo sapiens
Affinity Capture-Western Homo sapiens
FRET Homo sapiens
142 CTNND1 1500
Proximity Label-MS Homo sapiens
143 DERL1 79139
Affinity Capture-Western Homo sapiens
144 PTPRF 5792
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
145 Tmed2 56334
Affinity Capture-MS Mus musculus
146 USP6NL 9712
Proximity Label-MS Homo sapiens
147 Spast  
Affinity Capture-MS Mus musculus
148 ARHGAP39  
Proximity Label-MS Homo sapiens
149 ATG5 9474
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
150 TSC2 7249
Co-purification Homo sapiens
151 GJA1 2697
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
152 RPA2 6118
Affinity Capture-MS Homo sapiens
153 ARFGAP2 84364
Proximity Label-MS Homo sapiens
154 APC  
Proximity Label-MS Homo sapiens
155 DBN1 1627
Affinity Capture-MS Homo sapiens
156 PACSIN2 11252
Proximity Label-MS Homo sapiens
157 DTNA  
Proximity Label-MS Homo sapiens
158 TRIM33 51592
Affinity Capture-MS Homo sapiens
159 CNP 1267
Proximity Label-MS Homo sapiens
160 FMN2  
Proximity Label-MS Homo sapiens
161 VAMP2 6844
Proximity Label-MS Homo sapiens
162 IFNGR1 3459
Proximity Label-MS Homo sapiens
163 UFD1L 7353
Affinity Capture-Western Homo sapiens
164 TGFBR1 7046
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
165 KIF13B 23303
Proximity Label-MS Homo sapiens
166 VANGL2  
Proximity Label-MS Homo sapiens
167 PPP2R1B 5519
Affinity Capture-Western Homo sapiens
168 PGK1 5230
Proximity Label-MS Homo sapiens
169 USO1 8615
Proximity Label-MS Homo sapiens
170 LRRC1 55227
Proximity Label-MS Homo sapiens
171 GRK1  
Reconstituted Complex Homo sapiens
172 RRP12 23223
Proximity Label-MS Homo sapiens
173 TNIK 23043
Proximity Label-MS Homo sapiens
174 MAP4K5 11183
Proximity Label-MS Homo sapiens
175 C1qbp 12261
Affinity Capture-MS Mus musculus
176 PLCG1 5335
Affinity Capture-Western Homo sapiens
177 STEAP3 55240
Proximity Label-MS Homo sapiens
178 SUN2 25777
Affinity Capture-MS Homo sapiens
179 NCOA7  
Proximity Label-MS Homo sapiens
180 PTPN14 5784
Proximity Label-MS Homo sapiens
181 PALM 5064
Proximity Label-MS Homo sapiens
182 EBAG9 9166
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
183 SLC7A11 23657
Proximity Label-MS Homo sapiens
184 ABCC5 10057
Proximity Label-MS Homo sapiens
185 COBL  
Proximity Label-MS Homo sapiens
186 STAM2 10254
Proximity Label-MS Homo sapiens
187 CHMP7 91782
Proximity Label-MS Homo sapiens
188 MAPK3 5595
Affinity Capture-Western Homo sapiens
189 PTGS1 5742
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
190 VPS45 11311
Proximity Label-MS Homo sapiens
191 RUFY1 80230
Proximity Label-MS Homo sapiens
192 RAI14 26064
Proximity Label-MS Homo sapiens
193 C2CD4C  
Proximity Label-MS Homo sapiens
194 LYN 4067
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
195 PSMD14 10213
Affinity Capture-Western Homo sapiens
196 ACIN1 22985
Co-fractionation Homo sapiens
197 SNAP47 116841
Proximity Label-MS Homo sapiens
198 UBXN7 26043
Affinity Capture-MS Homo sapiens
199 ADD2 119
Proximity Label-MS Homo sapiens
200 MB21D2  
Proximity Label-MS Homo sapiens
201 RELL1 768211
Proximity Label-MS Homo sapiens
202 SCARB1 949
Proximity Label-MS Homo sapiens
203 LAMP1 3916
Proximity Label-MS Homo sapiens
204 PPP2CA 5515
Reconstituted Complex Homo sapiens
205 JAG2  
Proximity Label-MS Homo sapiens
206 ATP4A 495
Affinity Capture-MS Homo sapiens
207 STX5 6811
Proximity Label-MS Homo sapiens
208 FLRT3 23767
Proximity Label-MS Homo sapiens
209 ATG12  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
210 UBXN6 80700
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
211 PTGIS 5740
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
212 PTPN11 5781
Affinity Capture-Western Homo sapiens
213 CXCR4 7852
Co-fractionation Homo sapiens
214 RAB5A 5868
Proximity Label-MS Homo sapiens
215 ADCY9 115
Proximity Label-MS Homo sapiens
216 PPARG 5468
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Co-localization Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
217 ARVCF 421
Proximity Label-MS Homo sapiens
218 CAV2 858
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
219 MIS18A  
Affinity Capture-MS Homo sapiens
220 CDC42EP1 11135
Proximity Label-MS Homo sapiens
221 Rmdn3  
Affinity Capture-MS Mus musculus
222 RICTOR 253260
Proximity Label-MS Homo sapiens
223 EGFR 1956
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
PCA Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
224 AQP3  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
225 TMEM169  
Affinity Capture-MS Homo sapiens
226 GAB1  
Proximity Label-MS Homo sapiens
227 PLEKHA5 54477
Proximity Label-MS Homo sapiens
228 PCDH7 5099
Proximity Label-MS Homo sapiens
229 MYC  
Affinity Capture-MS Homo sapiens
230 SLC3A2 6520
Proximity Label-MS Homo sapiens
231 PKP4 8502
Proximity Label-MS Homo sapiens
232 CHRM5  
Affinity Capture-MS Homo sapiens
233 MICALL1 85377
Proximity Label-MS Homo sapiens
234 MET 4233
Affinity Capture-Western Homo sapiens
235 PEAK1 79834
Proximity Label-MS Homo sapiens
236 Junb  
Affinity Capture-MS Mus musculus
237 AHNAK2 113146
Proximity Label-MS Homo sapiens
238 SLC12A6 9990
Proximity Label-MS Homo sapiens
239 RHOB 388
Proximity Label-MS Homo sapiens
240 CCDC88A 55704
Proximity Label-MS Homo sapiens
241 VIMP 55829
Affinity Capture-Western Homo sapiens
242 LMNA 4000
Proximity Label-MS Homo sapiens
243 SLC37A3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
244 DENND4C 55667
Proximity Label-MS Homo sapiens
245 KRT18 3875
Proximity Label-MS Homo sapiens
246 SPTBN1 6711
Proximity Label-MS Homo sapiens
247 TMEM51 55092
Proximity Label-MS Homo sapiens
248 SEC24A 10802
Proximity Label-MS Homo sapiens
249 SLC38A2 54407
Proximity Label-MS Homo sapiens
250 TRAF2 7186
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
251 KIF14 9928
Affinity Capture-MS Homo sapiens
252 VPS13B  
Proximity Label-MS Homo sapiens
253 GOSR1 9527
Proximity Label-MS Homo sapiens
254 HDAC6 10013
Affinity Capture-Western Homo sapiens
255 KEAP1 9817
Proximity Label-MS Homo sapiens
256 DSC3 1825
Proximity Label-MS Homo sapiens
257 SQSTM1 8878
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
258 MMGT1 93380
Affinity Capture-MS Homo sapiens
259 ESR1  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
260 CHRM3 1131
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
261 AHCYL2 23382
Proximity Label-MS Homo sapiens
262 TNFRSF10B 8795
Co-fractionation Homo sapiens
263 BSG 682
Proximity Label-MS Homo sapiens
264 KIAA0754  
Proximity Label-MS Homo sapiens
265 DENND4A 10260
Proximity Label-MS Homo sapiens
266 ATP1A1 476
Proximity Label-MS Homo sapiens
267 YKT6 10652
Proximity Label-MS Homo sapiens
268 IGF2R 3482
Proximity Label-MS Homo sapiens
269 RPS6KC1  
Proximity Label-MS Homo sapiens
270 ATP6V0A2 23545
Affinity Capture-MS Homo sapiens
271 ANK3  
Proximity Label-MS Homo sapiens
272 GNAI3 2773
Proximity Label-MS Homo sapiens
273 PPP2R1A 5518
Affinity Capture-Western Homo sapiens
274 PTRF 284119
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
275 MAGI1  
Proximity Label-MS Homo sapiens
276 MAP1LC3B2  
Affinity Capture-MS Homo sapiens
277 CC2D1A 54862
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
278 RAB23 51715
Proximity Label-MS Homo sapiens
279 PTPRG 5793
Proximity Label-MS Homo sapiens
280 DLG5 9231
Proximity Label-MS Homo sapiens
281 SLC31A2  
Affinity Capture-MS Homo sapiens
282 CLCN7 1186
Proximity Label-MS Homo sapiens
283 ZDHHC5 25921
Proximity Label-MS Homo sapiens
284 CANT1 124583
Proximity Label-MS Homo sapiens
285 RCVRN  
Affinity Capture-Western Homo sapiens
286 OCLN 100506658
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
287 MARCKS 4082
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
288 LPAR6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
289 EFR3A 23167
Proximity Label-MS Homo sapiens
290 PARD3 56288
Proximity Label-MS Homo sapiens
291 SLC30A1 7779
Proximity Label-MS Homo sapiens
292 EPB41L5 57669
Proximity Label-MS Homo sapiens
293 Chmp4b 75608
Affinity Capture-MS Mus musculus
294 F2R 2149
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
295 ADGRL2 23266
Proximity Label-MS Homo sapiens
296 TRADD 8717
Affinity Capture-Western Homo sapiens
297 ADD3 120
Proximity Label-MS Homo sapiens
298 SHB 6461
Proximity Label-MS Homo sapiens
299 ARCN1 372
Proximity Label-MS Homo sapiens
300 TMEM2 23670
Proximity Label-MS Homo sapiens
301 PTPN1 5770
Affinity Capture-Western Homo sapiens
302 APBB1  
Proximity Label-MS Homo sapiens
303 MAP4K3 8491
Proximity Label-MS Homo sapiens
304 REEP4  
Affinity Capture-MS Homo sapiens
305 Kcnk1  
Affinity Capture-MS Mus musculus
306 SNX3 8724
Proximity Label-MS Homo sapiens
307 MLLT4 4301
Proximity Label-MS Homo sapiens
308 PAK4 10298
Proximity Label-MS Homo sapiens
309 FAM171A2 284069
Proximity Label-MS Homo sapiens
310 NUMBL 9253
Proximity Label-MS Homo sapiens
311 RAB3B 5865
Proximity Label-MS Homo sapiens
312 DSC2 1824
Proximity Label-MS Homo sapiens
313 CUEDC2  
Affinity Capture-MS Homo sapiens
314 SPRY4 81848
Proximity Label-MS Homo sapiens
315 PLD2 5338
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
316 PGD 5226
Proximity Label-MS Homo sapiens
317 CLTC 1213
Affinity Capture-MS Homo sapiens
318 SLC19A1 6573
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
319 ESYT2 57488
Proximity Label-MS Homo sapiens
320 VAPA 9218
Affinity Capture-MS Homo sapiens
321 GPRIN1 114787
Proximity Label-MS Homo sapiens
322 EHD1 10938
Proximity Label-MS Homo sapiens
323 METTL7A 25840
Proximity Label-MS Homo sapiens
324 FAS 355
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
325 LAMP3  
Proximity Label-MS Homo sapiens
326 PLEKHA1 59338
Proximity Label-MS Homo sapiens
327 GOLGA2 2801
Proximity Label-MS Homo sapiens
328 CAV3 859
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
329 EPB41L3 23136
Proximity Label-MS Homo sapiens
330 NF2 4771
Proximity Label-MS Homo sapiens
331 SLC1A3 6507
Proximity Label-MS Homo sapiens
332 IRS4 8471
Proximity Label-MS Homo sapiens
333 SCFD1 23256
Proximity Label-MS Homo sapiens
334 CPNE8 144402
Proximity Label-MS Homo sapiens
335 IRAK1  
Affinity Capture-Western Homo sapiens
336 ZFYVE16  
Proximity Label-MS Homo sapiens
337 ITGA6 3655
Proximity Label-MS Homo sapiens
338 ANTXR1 84168
Proximity Label-MS Homo sapiens
339 CTNNAL1 8727
Proximity Label-MS Homo sapiens
340 PTGS2 5743
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
341 IGF1R 3480
Co-localization Homo sapiens
342 CXADR 1525
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
343 NBR1 4077
Proximity Label-MS Homo sapiens
344 BET1L 51272
Proximity Label-MS Homo sapiens
345 RAB4A 5867
Proximity Label-MS Homo sapiens
346 DNAJC5 80331
Proximity Label-MS Homo sapiens
347 CHMP4B 128866
Affinity Capture-MS Homo sapiens
348 NUMB 8650
Proximity Label-MS Homo sapiens
349 DIRAS3  
Proximity Label-MS Homo sapiens
350 NGFR 4804
Reconstituted Complex Homo sapiens
351 NTRK1 4914
Affinity Capture-Western Homo sapiens
352 SMAD2 4087
Co-fractionation Homo sapiens
353 LRBA 987
Proximity Label-MS Homo sapiens
354 ACTB 60
Affinity Capture-Western Homo sapiens
355 PIK3R1 5295
Proximity Label-MS Homo sapiens
356 VAV2 7410
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
357 ARL13B 200894
Proximity Label-MS Homo sapiens
358 BMX  
Affinity Capture-Western Homo sapiens
359 TOM1L2 146691
Proximity Label-MS Homo sapiens
360 TTLL12 23170
Proximity Label-MS Homo sapiens
361 ITM2B 9445
Proximity Label-MS Homo sapiens
362 SLC4A7 9497
Proximity Label-MS Homo sapiens
363 NEU3  
Affinity Capture-Western Homo sapiens
364 Rab5c 19345
Affinity Capture-MS Mus musculus
365 OLA1 29789
Proximity Label-MS Homo sapiens
366 SMCR8 140775
Proximity Label-MS Homo sapiens
367 MARK3 4140
Proximity Label-MS Homo sapiens
368 ECT2 1894
Affinity Capture-MS Homo sapiens
369 TBC1D22B  
Proximity Label-MS Homo sapiens
370 FERMT2 10979
Proximity Label-MS Homo sapiens
371 PDGFRA 5156
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
372 HSD3B7 80270
Proximity Label-MS Homo sapiens
373 ENDOD1 23052
Affinity Capture-MS Homo sapiens
374 PTEN 5728
Affinity Capture-Western Homo sapiens
375 VAMP3 9341
Proximity Label-MS Homo sapiens
376 RIC1 57589
Proximity Label-MS Homo sapiens
377 GBF1 8729
Proximity Label-MS Homo sapiens
378 COX6B1 1340
Affinity Capture-MS Homo sapiens
379 YIPF5 81555
Affinity Capture-MS Homo sapiens
380 ECE1 1889
Proximity Label-MS Homo sapiens
381 OCIAD1 54940
Proximity Label-MS Homo sapiens
382 TBC1D8  
Proximity Label-MS Homo sapiens
383 CDC42BPA 8476
Proximity Label-MS Homo sapiens
384 SPTAN1 6709
Proximity Label-MS Homo sapiens
385 PTPN13 5783
Proximity Label-MS Homo sapiens
386 RAB9A 9367
Proximity Label-MS Homo sapiens
387 EPB41 2035
Proximity Label-MS Homo sapiens
388 PIK3CA 5290
Affinity Capture-MS Homo sapiens
389 PTPN23 25930
Proximity Label-MS Homo sapiens
390 STX3 6809
Proximity Label-MS Homo sapiens
391 ZC3HAV1 56829
Proximity Label-MS Homo sapiens
392 KIAA1522 57648
Proximity Label-MS Homo sapiens
393 MSN 4478
Proximity Label-MS Homo sapiens
394 SLC22A4 6583
Affinity Capture-MS Homo sapiens
395 HLA-A 3105
Proximity Label-MS Homo sapiens
396 TLR4  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
397 CASKIN2  
Proximity Label-MS Homo sapiens
398 FLOT1 10211
Co-fractionation Homo sapiens
Co-localization Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
399 SLC12A2 6558
Proximity Label-MS Homo sapiens
400 PIP5K1A 8394
Proximity Label-MS Homo sapiens
401 DEPDC1B 55789
Proximity Label-MS Homo sapiens
402 PVRL2 5819
Proximity Label-MS Homo sapiens
403 TACR1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
404 JUP 3728
Proximity Label-MS Homo sapiens
405 SEC23IP 11196
Proximity Label-MS Homo sapiens
406 NDUFAF2  
Proximity Label-MS Homo sapiens
407 MARK2 2011
Proximity Label-MS Homo sapiens
408 RHOC 389
Reconstituted Complex Homo sapiens
409 FAM171B  
Proximity Label-MS Homo sapiens
410 LSR 51599
Proximity Label-MS Homo sapiens
411 TALDO1 6888
Proximity Label-MS Homo sapiens
412 EPHA4 2043
Proximity Label-MS Homo sapiens
413 RPA1 6117
Affinity Capture-MS Homo sapiens
414 VAMP4 8674
Proximity Label-MS Homo sapiens
415 EFNB1 1947
Proximity Label-MS Homo sapiens
416 INSR 3643
Affinity Capture-Western Homo sapiens
417 ERGIC1 57222
Proximity Label-MS Homo sapiens
418 C11orf52 91894
Proximity Label-MS Homo sapiens
419 PPP1R9A  
Proximity Label-MS Homo sapiens
420 FGFR1OP2  
Affinity Capture-MS Homo sapiens
421 DNAJC5B  
Proximity Label-MS Homo sapiens
422 FRS2 10818
Proximity Label-MS Homo sapiens
423 RAB7A 7879
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
424 ROBO2 6092
Proximity Label-MS Homo sapiens
425 TULP3 7289
Proximity Label-MS Homo sapiens
426 Snca  
Reconstituted Complex Mus musculus
427 CD44 960
Co-localization Homo sapiens
428 AR 367
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
429 RAC1 5879
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
430 CNNM2 54805
Proximity Label-MS Homo sapiens
431 SEMA6A  
Proximity Label-MS Homo sapiens
432 GLIPR2 152007
Affinity Capture-Western Homo sapiens
433 NOTCH1 4851
Proximity Label-MS Homo sapiens
434 SLC5A3 6526
Proximity Label-MS Homo sapiens
435 HLA-C 3107
Proximity Label-MS Homo sapiens
436 UBE2H 7328
Affinity Capture-MS Homo sapiens
437 ADRBK1 156
Reconstituted Complex Homo sapiens
438 ARHGAP21 57584
Proximity Label-MS Homo sapiens
439 SLC29A1 2030
Proximity Label-MS Homo sapiens
440 C1orf198 84886
Proximity Label-MS Homo sapiens
441 SLC30A6 55676
Proximity Label-MS Homo sapiens
442 VTI1B 10490
Proximity Label-MS Homo sapiens
443 SNAP23 8773
Proximity Label-MS Homo sapiens
444 CSK 1445
Two-hybrid Homo sapiens
445 PPAP2B 8613
Proximity Label-MS Homo sapiens
446 AKAP12 9590
Proximity Label-MS Homo sapiens
447 NKD2 85409
Co-fractionation Homo sapiens
448 BID  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
449 SPECC1 92521
Proximity Label-MS Homo sapiens
450 ARFGAP3 26286
Proximity Label-MS Homo sapiens
451 LAMP2 3920
Proximity Label-MS Homo sapiens
452 BASP1 10409
Proximity Label-MS Homo sapiens
453 LNPEP 4012
Proximity Label-MS Homo sapiens
454 SLC22A9  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
455 APP 351
Co-fractionation Homo sapiens
Protein-RNA Homo sapiens
456 USP31 57478
Proximity Label-MS Homo sapiens
457 PDE2A  
Affinity Capture-MS Homo sapiens
458 KIAA1429 25962
Affinity Capture-MS Homo sapiens
459 B3GAT1  
Proximity Label-MS Homo sapiens
460 SLC39A14 23516
Proximity Label-MS Homo sapiens
461 JAG1 182
Proximity Label-MS Homo sapiens
462 LRP6 4040
Proximity Label-MS Homo sapiens
463 SLC39A10 57181
Proximity Label-MS Homo sapiens
464 SCRIB 23513
Proximity Label-MS Homo sapiens
465 DIAPH3 81624
Proximity Label-MS Homo sapiens
466 CPD 1362
Proximity Label-MS Homo sapiens
467 HGS 9146
Proximity Label-MS Homo sapiens
468 STX7 8417
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
469 PROCR 10544
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
470 ADD1 118
Proximity Label-MS Homo sapiens
471 UNC5C  
Proximity Label-MS Homo sapiens
472 TIAM1  
Proximity Label-MS Homo sapiens
473 AGTR1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
474 TOM1L1 10040
Affinity Capture-MS Homo sapiens
475 FAM135A  
Proximity Label-MS Homo sapiens
476 STX6 10228
Proximity Label-MS Homo sapiens
477 NEO1 4756
Proximity Label-MS Homo sapiens
478 RAB35 11021
Proximity Label-MS Homo sapiens
479 FAF2 23197
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
480 TNFRSF1B  
Affinity Capture-Western Homo sapiens
481 NEDD4 4734
Co-localization Homo sapiens
482 Lima1  
Affinity Capture-MS Mus musculus
483 VAMP8 8673
Proximity Label-MS Homo sapiens
484 LAMTOR1 55004
Proximity Label-MS Homo sapiens
485 TMEM63B 55362
Affinity Capture-MS Homo sapiens
486 TNF  
Affinity Capture-Western Homo sapiens
487 CASK 8573
Proximity Label-MS Homo sapiens
488 COBLL1 22837
Proximity Label-MS Homo sapiens
489 E2F4  
Affinity Capture-MS Homo sapiens
490 KRT8 3856
Co-fractionation Homo sapiens
491 PPP1CA 5499
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
492 ZDHHC8 29801
Proximity Label-MS Homo sapiens
493 Vcp 269523
Affinity Capture-Western Mus musculus
494 SLC5A6 8884
Affinity Capture-MS Homo sapiens
495 Tapt1  
Affinity Capture-MS Mus musculus
496 LPAR4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
497 TNKS1BP1 85456
Proximity Label-MS Homo sapiens
498 SCAMP1 9522
Proximity Label-MS Homo sapiens
499 CNNM3 26505
Proximity Label-MS Homo sapiens
500 PAG1 55824
Proximity Label-MS Homo sapiens
501 TRPC1  
Affinity Capture-Western Homo sapiens
502 PLD3 23646
Proximity Label-MS Homo sapiens
503 C19orf26 255057
Proximity Label-MS Homo sapiens
504 VCP 7415
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
505 S1PR1 1901
Affinity Capture-Western Homo sapiens
506 SLC7A2 6542
Proximity Label-MS Homo sapiens
507 GOPC 57120
Proximity Label-MS Homo sapiens
508 SMPD3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
509 COG3 83548
Proximity Label-MS Homo sapiens
510 MTMR1 8776
Proximity Label-MS Homo sapiens
511 PML 5371
Affinity Capture-MS Homo sapiens
512 BTK 695
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
513 ATP2B4 493
Proximity Label-MS Homo sapiens
514 TBC1D10B 26000
Proximity Label-MS Homo sapiens
515 ITCH 83737
Affinity Capture-Western Homo sapiens
516 ELOVL5 60481
Proximity Label-MS Homo sapiens
517 COG4 25839
Proximity Label-MS Homo sapiens
518 ACBD3 64746
Proximity Label-MS Homo sapiens
519 SNAP29 9342
Proximity Label-MS Homo sapiens
520 STK10 6793
Proximity Label-MS Homo sapiens
521 LIMA1 51474
Affinity Capture-MS Homo sapiens
522 CACHD1  
Proximity Label-MS Homo sapiens
523 RALGAPA1 253959
Proximity Label-MS Homo sapiens
524 GOLGA3 2802
Proximity Label-MS Homo sapiens
525 ROR1 4919
Proximity Label-MS Homo sapiens
526 FANCD2  
Affinity Capture-MS Homo sapiens
527 LMTK2 22853
Proximity Label-MS Homo sapiens
528 PTPN6 5777
Affinity Capture-Western Homo sapiens
529 PANX1 24145
Proximity Label-MS Homo sapiens
530 SLC39A6 25800
Proximity Label-MS Homo sapiens
531 ATP2B1 490
Proximity Label-MS Homo sapiens
532 NOS3  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
533 CTNNB1 1499
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
534 Bmpr1a  
Affinity Capture-MS Mus musculus
535 FAM171A1 221061
Proximity Label-MS Homo sapiens
536 SLC12A7 10723
Proximity Label-MS Homo sapiens
537 TRIO 7204
Proximity Label-MS Homo sapiens
538 PDIA3 2923
Affinity Capture-Western Homo sapiens
539 SLC7A5 8140
Proximity Label-MS Homo sapiens
540 ARF6 382
Proximity Label-MS Homo sapiens
541 HTR2C  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
542 KCNN3  
Affinity Capture-Western Homo sapiens
543 EHBP1 23301
Proximity Label-MS Homo sapiens
544 NXF1 10482
Affinity Capture-RNA Homo sapiens
545 EPHA7 2045
Proximity Label-MS Homo sapiens
546 PRKCI 5584
Proximity Label-MS Homo sapiens
547 LZTS2 84445
Proximity Label-MS Homo sapiens
548 PRKACA 5566
Affinity Capture-Western Homo sapiens
549 KIRREL 55243
Proximity Label-MS Homo sapiens
550 MYO6 4646
Proximity Label-MS Homo sapiens
551 SEC31A 22872
Proximity Label-MS Homo sapiens
552 AKAP5  
Proximity Label-MS Homo sapiens
553 ERBB2 2064
Proximity Label-MS Homo sapiens
554 PPFIBP1 8496
Proximity Label-MS Homo sapiens
555 HK1 3098
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
556 P2RY10  
Affinity Capture-MS Homo sapiens
557 VDAC1 7416
Affinity Capture-Western Homo sapiens
558 KRAS 3845
Proximity Label-MS Homo sapiens
559 PPFIA1 8500
Proximity Label-MS Homo sapiens
560 PDE3A  
Affinity Capture-MS Homo sapiens
561 CCDC8  
Proximity Label-MS Homo sapiens
562 P2RY12 64805
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
563 SEC24B 10427
Proximity Label-MS Homo sapiens
564 AK4 205
Affinity Capture-MS Homo sapiens
565 FNDC4 64838
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
566 SNCA 6622
Reconstituted Complex Homo sapiens
567 CUX1 1523
Proximity Label-MS Homo sapiens
568 KIAA1549  
Proximity Label-MS Homo sapiens
569 ITGA5 3678
Proximity Label-MS Homo sapiens
570 ANKFY1 51479
Proximity Label-MS Homo sapiens
571 FAP 2191
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
572 Clic4 83718
Co-fractionation Rattus norvegicus
573 EPHB2 2048
Proximity Label-MS Homo sapiens
574 UBA52 7311
Proximity Label-MS Homo sapiens
575 LMAN1 3998
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
576 PIK3CB 5291
Affinity Capture-MS Homo sapiens
577 NISCH 11188
Proximity Label-MS Homo sapiens
578 EPB41L2 2037
Proximity Label-MS Homo sapiens
579 MAPK1 5594
Affinity Capture-Western Homo sapiens
580 ROR2 4920
Proximity Label-MS Homo sapiens
581 ITGAV 3685
Proximity Label-MS Homo sapiens
582 MOV10 4343
Affinity Capture-RNA Homo sapiens
583 SLC5A8 160728
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
584 MICAL3 57553
Proximity Label-MS Homo sapiens
585 SLC38A1 81539
Proximity Label-MS Homo sapiens
586 SLC6A8 6535
Proximity Label-MS Homo sapiens
587 CYB5R3 1727
Affinity Capture-MS Homo sapiens
588 PIK3R2 5296
Proximity Label-MS Homo sapiens
589 GCC1 79571
Proximity Label-MS Homo sapiens
590 Ptpn23 104831
Affinity Capture-MS Mus musculus
591 RAPGEF6 51735
Proximity Label-MS Homo sapiens
592 ESYT1 23344
Proximity Label-MS Homo sapiens
593 DSG2 1829
Proximity Label-MS Homo sapiens
View the network image/svg+xml
 Pathways in which CAV1 is involved
PathwayEvidenceSource
Basigin interactions TAS Reactome
CDC42 GTPase cycle TAS Reactome
Cell surface interactions at the vascular wall TAS Reactome
Disassembly of the destruction complex and recruitment of AXIN to the membrane TAS Reactome
Disease IEA Reactome
Disease TAS Reactome
eNOS activation TAS Reactome
ESR-mediated signaling TAS Reactome
Extra-nuclear estrogen signaling TAS Reactome
FOXO-mediated transcription TAS Reactome
FOXO-mediated transcription of cell cycle genes TAS Reactome
Gene expression (Transcription) TAS Reactome
Generic Transcription Pathway TAS Reactome
Hemostasis TAS Reactome
Infectious disease IEA Reactome
Infectious disease TAS Reactome
Metabolism TAS Reactome
Metabolism IEA Reactome
Metabolism of lipids IEA Reactome
Metabolism of nitric oxide: NOS3 activation and regulation TAS Reactome
NOSTRIN mediated eNOS trafficking TAS Reactome
RAC1 GTPase cycle TAS Reactome
RAC2 GTPase cycle TAS Reactome
RAC3 GTPase cycle TAS Reactome
RHO GTPase cycle TAS Reactome
RHOA GTPase cycle TAS Reactome
RHOB GTPase cycle TAS Reactome
RHOC GTPase cycle TAS Reactome
RHOD GTPase cycle TAS Reactome
RHOF GTPase cycle TAS Reactome
RHOG GTPase cycle TAS Reactome
RHOH GTPase cycle TAS Reactome
RHOJ GTPase cycle TAS Reactome
RHOQ GTPase cycle TAS Reactome
RNA Polymerase II Transcription TAS Reactome
RND1 GTPase cycle TAS Reactome
RND2 GTPase cycle TAS Reactome
RND3 GTPase cycle TAS Reactome
SARS-CoV Infections IEA Reactome
SARS-CoV Infections TAS Reactome
SARS-CoV-1 Infection TAS Reactome
SARS-CoV-1 targets host intracellular signalling and regulatory pathways TAS Reactome
SARS-CoV-1-host interactions TAS Reactome
SARS-CoV-2 Infection IEA Reactome
SARS-CoV-2 targets host intracellular signalling and regulatory pathways IEA Reactome
SARS-CoV-2-host interactions IEA Reactome
Signal Transduction TAS Reactome
Signaling by Nuclear Receptors TAS Reactome
Signaling by Receptor Tyrosine Kinases TAS Reactome
Signaling by Rho GTPases TAS Reactome
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 TAS Reactome
Signaling by VEGF TAS Reactome
Signaling by WNT TAS Reactome
TCF dependent signaling in response to WNT TAS Reactome
Triglyceride catabolism IEA Reactome
Triglyceride metabolism IEA Reactome
VEGFA-VEGFR2 Pathway TAS Reactome
VEGFR2 mediated vascular permeability TAS Reactome
Viral Infection Pathways IEA Reactome
Viral Infection Pathways TAS Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here