Gene description for ANKRD13A
Gene name ankyrin repeat domain 13A
Gene symbol ANKRD13A
Other names/aliases ANKRD13
NY-REN-25
Species Homo sapiens
 Database cross references - ANKRD13A
ExoCarta ExoCarta_88455
Vesiclepedia VP_88455
Entrez Gene 88455
HGNC 21268
MIM 615123
UniProt Q8IZ07  
 ANKRD13A identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
Prostate cancer cells 25844599    
 Gene ontology annotations for ANKRD13A
Molecular Function
    ubiquitin-modified protein reader activity GO:0140036 IDA
    ubiquitin-modified protein reader activity GO:0140036 IPI
Biological Process
    negative regulation of receptor internalization GO:0002091 IMP
    negative regulation of protein localization to endosome GO:1905667 IDA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    late endosome GO:0005770 IDA
    plasma membrane GO:0005886 IDA
    perinuclear region of cytoplasm GO:0048471 IDA
 Experiment description of studies that identified ANKRD13A in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 274
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
 Protein-protein interactions for ANKRD13A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TNFAIP3 7128
Affinity Capture-Western Homo sapiens
2 IZUMO1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 SLC39A4 55630
Affinity Capture-MS Homo sapiens
4 STMN4  
Affinity Capture-MS Homo sapiens
5 MS4A10  
Affinity Capture-MS Homo sapiens
6 FBXO25  
Biochemical Activity Homo sapiens
7 CSNK1G3 1456
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 FAM153C  
Affinity Capture-MS Homo sapiens
9 UBC 7316
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
10 RIPK1 8737
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
11 DNAJB3 414061
Affinity Capture-MS Homo sapiens
12 FFAR1  
Affinity Capture-MS Homo sapiens
13 ARHGDIA 396
Affinity Capture-MS Homo sapiens
14 CTDSP2 10106
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 C22orf42  
Affinity Capture-MS Homo sapiens
16 ZDHHC11  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 DDX58 23586
Affinity Capture-RNA Homo sapiens
18 HAUS6  
Affinity Capture-MS Homo sapiens
19 SLC2A8 29988
Affinity Capture-MS Homo sapiens
20 FKBP11 51303
Affinity Capture-MS Homo sapiens
21 TCP11L1 55346
Affinity Capture-MS Homo sapiens
22 LDLRAD4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 SMAD5 4090
Two-hybrid Homo sapiens
24 CYSTM1 84418
Affinity Capture-MS Homo sapiens
25 WBP2 23558
Two-hybrid Homo sapiens
26 ARHGEF4  
Affinity Capture-MS Homo sapiens
27 HAUS4  
Affinity Capture-MS Homo sapiens
28 RNF11 26994
Two-hybrid Homo sapiens
29 TOLLIP 54472
Affinity Capture-MS Homo sapiens
30 DESI2  
Affinity Capture-MS Homo sapiens
31 MARCH7  
Affinity Capture-MS Homo sapiens
32 TSPAN33 340348
Affinity Capture-MS Homo sapiens
33 ARRDC1 92714
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 PSMD4 5710
Co-fractionation Homo sapiens
35 WBP1  
Affinity Capture-MS Homo sapiens
36 STOM 2040
Affinity Capture-MS Homo sapiens
37 RALA 5898
Affinity Capture-MS Homo sapiens
38 LAPTM5 7805
Two-hybrid Homo sapiens
39 EXPH5  
Affinity Capture-MS Homo sapiens
40 HAUS8  
Affinity Capture-MS Homo sapiens
41 VCP 7415
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
42 NTRK1 4914
Affinity Capture-MS Homo sapiens
43 NCR1  
Affinity Capture-MS Homo sapiens
44 TMEM171  
Affinity Capture-MS Homo sapiens
45 LRRC3B  
Affinity Capture-MS Homo sapiens
46 MTR 4548
Affinity Capture-MS Homo sapiens
47 KCNIP2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
48 PRRG4  
Affinity Capture-MS Homo sapiens
49 FAM189B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 HLA-DPB1 3115
Affinity Capture-MS Homo sapiens
51 RNF219  
Affinity Capture-MS Homo sapiens
52 SCAMP2 10066
Affinity Capture-MS Homo sapiens
53 CXCR4 7852
Affinity Capture-MS Homo sapiens
54 DCK 1633
Affinity Capture-MS Homo sapiens
55 STMN2  
Affinity Capture-MS Homo sapiens
56 XPO1 7514
Affinity Capture-MS Homo sapiens
57 ARRDC4  
Affinity Capture-MS Homo sapiens
58 RALB 5899
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
59 TRIM10  
Affinity Capture-MS Homo sapiens
60 ERGIC3 51614
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
61 EGFR 1956
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
62 RPS27A 6233
Affinity Capture-MS Homo sapiens
63 PI4K2A 55361
Affinity Capture-MS Homo sapiens
64 MLF1  
Affinity Capture-MS Homo sapiens
65 FAM153A  
Affinity Capture-MS Homo sapiens
66 SLC10A1  
Affinity Capture-MS Homo sapiens
67 UBTD1 80019
Affinity Capture-MS Homo sapiens
68 RHOB 388
Affinity Capture-MS Homo sapiens
69 KCNMB2  
Affinity Capture-MS Homo sapiens
70 HAUS3  
Affinity Capture-MS Homo sapiens
71 ZRANB1 54764
Affinity Capture-MS Homo sapiens
72 TMEM51 55092
Affinity Capture-MS Homo sapiens
73 FADD 8772
Affinity Capture-Western Homo sapiens
74 TSPAN5 10098
Affinity Capture-MS Homo sapiens
75 FAM153B  
Affinity Capture-MS Homo sapiens
76 EDNRA 1909
Affinity Capture-MS Homo sapiens
77 CTDSP1 58190
Affinity Capture-MS Homo sapiens
78 HAUS1  
Affinity Capture-MS Homo sapiens
79 PPIP5K1 9677
Affinity Capture-MS Homo sapiens
80 LRRCC1  
Affinity Capture-MS Homo sapiens
81 RP2 6102
Affinity Capture-MS Homo sapiens
82 CASP8 841
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
83 TSPAN17 26262
Affinity Capture-MS Homo sapiens
84 SMURF1 57154
Biochemical Activity Homo sapiens
85 ZNRF1  
Affinity Capture-MS Homo sapiens
86 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
87 DLK1  
Affinity Capture-MS Homo sapiens
88 SLAMF1 6504
Affinity Capture-MS Homo sapiens
89 PGAP3  
Affinity Capture-MS Homo sapiens
90 ASB7  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
91 DIO3  
Affinity Capture-MS Homo sapiens
92 QDPR 5860
Two-hybrid Homo sapiens
93 WDR59 79726
Affinity Capture-MS Homo sapiens
94 FAM189A2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
95 KCNIP4 80333
Affinity Capture-MS Homo sapiens
96 ADGRE5 976
Affinity Capture-MS Homo sapiens
97 TMEM31  
Affinity Capture-MS Homo sapiens
98 CCR6  
Affinity Capture-MS Homo sapiens
99 TXNDC8 255220
Affinity Capture-MS Homo sapiens
100 CAV1 857
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
101 PDRG1  
Affinity Capture-MS Homo sapiens
102 B3GNT8  
Affinity Capture-MS Homo sapiens
103 KIAA1644  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ANKRD13A is involved
No pathways found





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