Gene description for UBXN1
Gene name UBX domain protein 1
Gene symbol UBXN1
Other names/aliases 2B28
SAKS1
UBXD10
Species Homo sapiens
 Database cross references - UBXN1
ExoCarta ExoCarta_51035
Vesiclepedia VP_51035
Entrez Gene 51035
HGNC 18402
UniProt Q04323  
 UBXN1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Mesenchymal stem cells 36408942    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Thymus 23844026    
 Gene ontology annotations for UBXN1
Molecular Function
    protein binding GO:0005515 IPI
    polyubiquitin modification-dependent protein binding GO:0031593 IDA
    ubiquitin protein ligase binding GO:0031625 IDA
    K48-linked polyubiquitin modification-dependent protein binding GO:0036435 IBA
    K48-linked polyubiquitin modification-dependent protein binding GO:0036435 IDA
    ubiquitin binding GO:0043130 IDA
    ATPase binding GO:0051117 IPI
    K6-linked polyubiquitin modification-dependent protein binding GO:0071796 IDA
    proteasome regulatory particle binding GO:1904855 IDA
Biological Process
    negative regulation of protein ubiquitination GO:0031397 IBA
    negative regulation of protein ubiquitination GO:0031397 IDA
    negative regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032435 IBA
    negative regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032435 IDA
    proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161 NAS
    negative regulation of protein K48-linked deubiquitination GO:1903094 IBA
    negative regulation of protein K48-linked deubiquitination GO:1903094 IDA
    negative regulation of ERAD pathway GO:1904293 IMP
    negative regulation of ubiquitin-specific protease activity GO:2000157 IDA
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    endoplasmic reticulum GO:0005783 IDA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    VCP-NPL4-UFD1 AAA ATPase complex GO:0034098 IDA
 Experiment description of studies that identified UBXN1 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
6
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
9
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
15
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
19
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for UBXN1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SEC22B 9554
Co-fractionation Homo sapiens
2 LY86  
Affinity Capture-MS Homo sapiens
3 A1BG 1
Affinity Capture-MS Homo sapiens
4 DENR 8562
Co-fractionation Homo sapiens
5 ISG15 9636
Affinity Capture-MS Homo sapiens
6 ATPIF1 93974
Cross-Linking-MS (XL-MS) Homo sapiens
7 SPRTN  
Affinity Capture-MS Homo sapiens
8 CLIP1 6249
Cross-Linking-MS (XL-MS) Homo sapiens
9 KCTD10 83892
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 RPA2 6118
Co-fractionation Homo sapiens
11 BRCA1 672
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
12 GMCL1P1  
Affinity Capture-MS Homo sapiens
13 UBE3A 7337
Affinity Capture-MS Homo sapiens
14 USP9X 8239
Co-fractionation Homo sapiens
15 PRPSAP2 5636
Affinity Capture-MS Homo sapiens
16 UBC 7316
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
17 CSE1L 1434
Co-fractionation Homo sapiens
18 VAMP2 6844
Co-fractionation Homo sapiens
19 CCDC102B  
Affinity Capture-MS Homo sapiens
20 KIAA1598 57698
Co-fractionation Homo sapiens
21 BTBD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 EMILIN1 11117
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 CTLA4  
Affinity Capture-MS Homo sapiens
24 MCM2 4171
Affinity Capture-MS Homo sapiens
25 WDR20 91833
Affinity Capture-MS Homo sapiens
26 TWF2 11344
Co-fractionation Homo sapiens
27 UBE2A  
Co-fractionation Homo sapiens
28 MCTS1 28985
Co-fractionation Homo sapiens
29 PPP1R7 5510
Affinity Capture-Western Homo sapiens
30 UBQLN1 29979
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
31 VPS4B 9525
Co-fractionation Homo sapiens
32 MID2 11043
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
33 FAF1 11124
Affinity Capture-MS Homo sapiens
34 TAGLN3 29114
Co-fractionation Homo sapiens
35 BIRC3 330
Affinity Capture-MS Homo sapiens
36 HDAC8 55869
Affinity Capture-MS Homo sapiens
37 MAVS 57506
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
38 CUL1 8454
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
39 UBQLN4 56893
Co-fractionation Homo sapiens
40 TWF1 5756
Co-fractionation Homo sapiens
41 YAF2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
42 PSMC3 5702
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 RAD23A 5886
Two-hybrid Homo sapiens
44 PRPS2 5634
Affinity Capture-MS Homo sapiens
45 FAS 355
Proximity Label-MS Homo sapiens
46 UNC45A 55898
Co-fractionation Homo sapiens
47 E2F4  
Affinity Capture-MS Homo sapiens
48 UBR4 23352
Affinity Capture-MS Homo sapiens
49 ACAT2 39
Co-fractionation Homo sapiens
50 UBE4B 10277
Affinity Capture-MS Homo sapiens
51 DSG1 1828
Affinity Capture-MS Homo sapiens
52 MARCH7  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 PSMD4 5710
Affinity Capture-Western Homo sapiens
54 SPDL1  
Co-fractionation Homo sapiens
55 AMFR 267
Affinity Capture-MS Homo sapiens
56 CLNS1A 1207
Co-fractionation Homo sapiens
57 BAG6 7917
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
58 TUFM 7284
Co-fractionation Homo sapiens
59 UBE2I 7329
Two-hybrid Homo sapiens
60 USP47 55031
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
61 UBR5 51366
Affinity Capture-MS Homo sapiens
62 YWHAE 7531
Co-fractionation Homo sapiens
63 VCP 7415
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
64 TTN 7273
Cross-Linking-MS (XL-MS) Homo sapiens
65 UBE2L3 7332
Co-fractionation Homo sapiens
66 CDK5R1  
Affinity Capture-MS Homo sapiens
67 SMC1A 8243
Cross-Linking-MS (XL-MS) Homo sapiens
68 CTPS1 1503
Co-fractionation Homo sapiens
69 CUL2 8453
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
70 VCPIP1 80124
Affinity Capture-MS Homo sapiens
71 PROSC 11212
Co-fractionation Homo sapiens
72 CEBPA  
Protein-peptide Homo sapiens
73 DNAJB11 51726
Co-fractionation Homo sapiens
74 UBXN6 80700
Affinity Capture-MS Homo sapiens
75 USP32 84669
Affinity Capture-MS Homo sapiens
76 BARD1 580
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
77 IGBP1 3476
Co-fractionation Homo sapiens
78 ZPR1 8882
Co-fractionation Homo sapiens
79 HSPA5 3309
Co-fractionation Homo sapiens
80 PLAA 9373
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
81 TUBB2A 7280
Co-fractionation Homo sapiens
82 UFC1 51506
Co-fractionation Homo sapiens
83 AHCYL1 10768
Co-fractionation Homo sapiens
84 PLA2G4A 5321
Two-hybrid Homo sapiens
85 UBXN7 26043
Affinity Capture-MS Homo sapiens
86 S100A16 140576
Co-fractionation Homo sapiens
87 NPTN 27020
Co-fractionation Homo sapiens
88 RLIM 51132
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
89 TRA  
Affinity Capture-Western Homo sapiens
90 CUL3 8452
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
91 RPGRIP1  
Cross-Linking-MS (XL-MS) Homo sapiens
92 TXNRD1 7296
Co-fractionation Homo sapiens
93 NSFL1C 55968
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
94 KLRG2 346689
Affinity Capture-MS Homo sapiens
95 METTL21B  
Affinity Capture-MS Homo sapiens
96 KBTBD7  
Affinity Capture-MS Homo sapiens
97 ZFYVE19 84936
Co-fractionation Homo sapiens
98 BASP1 10409
Co-fractionation Homo sapiens
99 DUSP6 1848
Affinity Capture-MS Homo sapiens
100 NXF1 10482
Affinity Capture-RNA Homo sapiens
101 UBL4A 8266
Affinity Capture-MS Homo sapiens
102 KLHL22 84861
Affinity Capture-MS Homo sapiens
103 NPLOC4 55666
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
104 HOMER2  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
105 UBR1 197131
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
106 PRPF19 27339
Co-fractionation Homo sapiens
107 RPA3 6119
Co-fractionation Homo sapiens
108 ATP6V1A 523
Co-fractionation Homo sapiens
109 SHKBP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
110 FAF2 23197
Affinity Capture-MS Homo sapiens
111 DDB1 1642
Affinity Capture-MS Homo sapiens
112 KLHL10  
Affinity Capture-MS Homo sapiens
113 TNFRSF1B  
Affinity Capture-MS Homo sapiens
114 TXNDC5 81567
Co-fractionation Homo sapiens
115 MSN 4478
Cross-Linking-MS (XL-MS) Homo sapiens
116 TRNT1 51095
Co-fractionation Homo sapiens
117 TRIM39  
Two-hybrid Homo sapiens
118 C9orf72  
Affinity Capture-MS Homo sapiens
119 UBXN1 51035
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
120 HUWE1 10075
Affinity Capture-MS Homo sapiens
121 AQP9  
Affinity Capture-MS Homo sapiens
122 HIF1A 3091
Affinity Capture-Western Homo sapiens
123 PAFAH1B1 5048
Co-fractionation Homo sapiens
124 UBQLN2 29978
Two-hybrid Homo sapiens
125 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
126 UBR2 23304
Affinity Capture-MS Homo sapiens
127 TTC1 7265
Co-fractionation Homo sapiens
128 JUP 3728
Affinity Capture-MS Homo sapiens
129 GAR1 54433
Affinity Capture-MS Homo sapiens
130 USP34 9736
Co-fractionation Homo sapiens
131 ASF1B  
Affinity Capture-MS Homo sapiens
132 TNFAIP1 7126
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
133 SULT1A1 6817
Co-fractionation Homo sapiens
134 ASPSCR1 79058
Cross-Linking-MS (XL-MS) Homo sapiens
135 RPA1 6117
Co-fractionation Homo sapiens
136 UFD1L 7353
Affinity Capture-Western Homo sapiens
137 SQSTM1 8878
Affinity Capture-MS Homo sapiens
138 DSC1 1823
Affinity Capture-MS Homo sapiens
139 UBE2C 11065
Co-fractionation Homo sapiens
140 PJA2  
Affinity Capture-MS Homo sapiens
141 VTA1 51534
Co-fractionation Homo sapiens
142 STK26 51765
Co-fractionation Homo sapiens
143 GET4 51608
Affinity Capture-MS Homo sapiens
144 AARSD1 80755
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
145 UNK  
Co-fractionation Homo sapiens
146 PSMA1 5682
Affinity Capture-MS Homo sapiens
147 BABAM1 29086
Affinity Capture-MS Homo sapiens
148 BTBD2  
Affinity Capture-MS Homo sapiens
149 POLR3C 10623
Two-hybrid Homo sapiens
150 MAGED1 9500
Affinity Capture-MS Homo sapiens
151 CDK4 1019
Affinity Capture-MS Homo sapiens
152 HK1 3098
Co-fractionation Homo sapiens
153 CEP135  
Cross-Linking-MS (XL-MS) Homo sapiens
154 TCAF1 9747
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
155 SSSCA1 10534
Co-fractionation Homo sapiens
156 ALPP 250
Affinity Capture-MS Homo sapiens
157 FAM189A2  
Two-hybrid Homo sapiens
158 SERBP1 26135
Affinity Capture-MS Homo sapiens
159 MYO6 4646
Affinity Capture-MS Homo sapiens
160 PIPSL 266971
Co-fractionation Homo sapiens
161 PPP1CB 5500
Affinity Capture-MS Homo sapiens
162 BTBD9  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
163 KLHL12  
Affinity Capture-MS Homo sapiens
164 HMGB3 3149
Co-fractionation Homo sapiens
165 UBE2V2 7336
Co-fractionation Homo sapiens
166 UFM1 51569
Co-fractionation Homo sapiens
167 CAPN2 824
Co-fractionation Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here