Gene description for TPM2
Gene name tropomyosin 2 (beta)
Gene symbol TPM2
Other names/aliases AMCD1
DA1
DA2B
HEL-S-273
NEM4
TMSB
Species Homo sapiens
 Database cross references - TPM2
ExoCarta ExoCarta_7169
Vesiclepedia VP_7169
Entrez Gene 7169
HGNC 12011
MIM 190990
UniProt P07951  
 TPM2 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Keratinocytes 19530224    
Keratinocytes 19530224    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
 Gene ontology annotations for TPM2
Molecular Function
    actin binding GO:0003779 IDA
    protein binding GO:0005515 IPI
    structural constituent of muscle GO:0008307 TAS
    identical protein binding GO:0042802 IPI
    identical protein binding GO:0042802 ISS
    protein homodimerization activity GO:0042803 ISS
    protein heterodimerization activity GO:0046982 ISS
    actin filament binding GO:0051015 IBA
    actin filament binding GO:0051015 ISS
Biological Process
    muscle contraction GO:0006936 IBA
    actin filament organization GO:0007015 IBA
    regulation of ATP-dependent activity GO:0043462 IDA
Subcellular Localization
    cytosol GO:0005829 TAS
    muscle thin filament tropomyosin GO:0005862 TAS
    actin filament GO:0005884 IBA
    actin cytoskeleton GO:0015629 ISS
 Experiment description of studies that identified TPM2 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
6
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
7
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
9
Experiment ID 189
MISEV standards
✔
EM
Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors "Chavez-Muñoz C, Kilani RT, Ghahary A."
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Differentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 190
MISEV standards
✔
EM
Biophysical techniques
✔
HSC70
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors "Chavez-Muñoz C, Kilani RT, Ghahary A."
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Undifferentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TPM2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ATAD1 84896
Affinity Capture-MS Homo sapiens
2 CCAR1 55749
Co-fractionation Homo sapiens
3 ISG15 9636
Affinity Capture-MS Homo sapiens
4 INSIG1  
Affinity Capture-MS Homo sapiens
5 PPP1CB 5500
Affinity Capture-MS Homo sapiens
6 Tpm1 22003
Affinity Capture-MS Mus musculus
7 SUB1 10923
Co-fractionation Homo sapiens
8 SYCE1  
Affinity Capture-MS Homo sapiens
9 LGALS9C  
Affinity Capture-MS Homo sapiens
10 TPM2 7169
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
11 SP1  
Affinity Capture-MS Homo sapiens
12 Calml3  
Affinity Capture-MS Mus musculus
13 TMEM205 374882
Affinity Capture-MS Homo sapiens
14 RRAD 6236
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
15 ACTA1 58
Reconstituted Complex Homo sapiens
16 KIF20A 10112
Affinity Capture-MS Homo sapiens
17 CKMT1B 1159
Co-fractionation Homo sapiens
18 SSB 6741
Co-fractionation Homo sapiens
19 MYO5C 55930
Affinity Capture-MS Homo sapiens
20 Actb 11461
Affinity Capture-MS Mus musculus
21 SEPT2 4735
Affinity Capture-MS Homo sapiens
22 TMPO 7112
Affinity Capture-MS Homo sapiens
23 PCGF2 7703
Affinity Capture-MS Homo sapiens
24 GOLGA7 51125
Affinity Capture-MS Homo sapiens
25 KIAA1429 25962
Affinity Capture-MS Homo sapiens
26 CAPZB 832
Co-fractionation Homo sapiens
27 CORO1B 57175
Co-fractionation Homo sapiens
28 B3GNT2 10678
Affinity Capture-MS Homo sapiens
29 DSTN 11034
Co-fractionation Homo sapiens
30 MYH6 4624
Co-fractionation Homo sapiens
31 DYRK1A 1859
Affinity Capture-MS Homo sapiens
32 STOX1  
Affinity Capture-MS Homo sapiens
33 CKMT1A 548596
Co-fractionation Homo sapiens
34 RRM2B 50484
Affinity Capture-MS Homo sapiens
35 FBXW7  
Affinity Capture-MS Homo sapiens
36 IQGAP1 8826
Affinity Capture-MS Homo sapiens
37 CPSF7 79869
Co-fractionation Homo sapiens
38 ADD1 118
Affinity Capture-MS Homo sapiens
39 Flot2 14252
Affinity Capture-MS Mus musculus
40 POC1B 282809
Affinity Capture-MS Homo sapiens
41 PSMD5 5711
Co-fractionation Homo sapiens
42 SLC4A1AP  
Co-fractionation Homo sapiens
43 MYCN  
Affinity Capture-MS Homo sapiens
44 Lima1  
Affinity Capture-MS Mus musculus
45 AHCYL1 10768
Co-fractionation Homo sapiens
46 MYL6 4637
Co-fractionation Homo sapiens
47 NINL  
Affinity Capture-MS Homo sapiens
48 KANSL1  
Affinity Capture-MS Homo sapiens
49 SLC25A48  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 FARS2 10667
Two-hybrid Homo sapiens
51 MYO18A 399687
Affinity Capture-MS Homo sapiens
52 POF1B 79983
Affinity Capture-MS Homo sapiens
53 MAPK3 5595
Affinity Capture-MS Homo sapiens
54 NEB 4703
Reconstituted Complex Homo sapiens
55 RHOBTB2  
Affinity Capture-MS Homo sapiens
56 TFCP2 7024
Affinity Capture-MS Homo sapiens
57 MAGEA10  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
58 SCG3  
Affinity Capture-MS Homo sapiens
59 FAM9C  
Affinity Capture-MS Homo sapiens
60 NONO 4841
Co-fractionation Homo sapiens
61 RSPH6A  
Affinity Capture-MS Homo sapiens
62 ZNF22  
Affinity Capture-MS Homo sapiens
63 TPM4 7171
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
64 PDLIM5 10611
Affinity Capture-MS Homo sapiens
65 CCDC51 79714
Affinity Capture-MS Homo sapiens
66 RPA2 6118
Affinity Capture-MS Homo sapiens
67 MYH9 4627
Affinity Capture-MS Homo sapiens
68 VCP 7415
Affinity Capture-MS Homo sapiens
69 ACTN4 81
Co-fractionation Homo sapiens
70 CDK5R1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 SLC47A1  
Affinity Capture-MS Homo sapiens
72 Coro1c 23790
Affinity Capture-MS Mus musculus
73 SEMA6D  
Affinity Capture-MS Homo sapiens
74 MYH3 4621
Co-fractionation Homo sapiens
75 CFHR3 10878
Affinity Capture-MS Homo sapiens
76 YAP1 10413
Affinity Capture-MS Homo sapiens
77 HAS3  
Affinity Capture-MS Homo sapiens
78 STAM 8027
Co-fractionation Homo sapiens
79 COX4I1 1327
Co-fractionation Homo sapiens
80 MESDC2 23184
Two-hybrid Homo sapiens
81 ANLN 54443
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
82 FAM189B  
Affinity Capture-MS Homo sapiens
83 ACTN1 87
Co-fractionation Homo sapiens
84 SF3B2 10992
Co-fractionation Homo sapiens
85 AGBL2  
Affinity Capture-MS Homo sapiens
86 TAF15 8148
Co-fractionation Homo sapiens
87 HADHA 3030
Cross-Linking-MS (XL-MS) Homo sapiens
88 Myh9 17886
Affinity Capture-MS Mus musculus
89 NDUFB10 4716
Co-fractionation Homo sapiens
90 C11orf70  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
91 ECT2 1894
Affinity Capture-MS Homo sapiens
92 SRXN1 140809
Co-fractionation Homo sapiens
93 FAM60A  
Affinity Capture-MS Homo sapiens
94 UQCRC2 7385
Co-fractionation Homo sapiens
95 AKAP9 10142
Affinity Capture-MS Homo sapiens
96 STK17B 9262
Affinity Capture-MS Homo sapiens
97 MEX3A  
Affinity Capture-RNA Homo sapiens
98 BCAP31 10134
Co-fractionation Homo sapiens
99 Itga5 16402
Affinity Capture-MS Mus musculus
100 ATP5F1 515
Co-fractionation Homo sapiens
101 EBNA1BP2 10969
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
102 CIART  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
103 ZNF250  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
104 TFPT  
Two-hybrid Homo sapiens
105 MYO19  
Affinity Capture-MS Homo sapiens
106 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
107 AURKB 9212
Affinity Capture-MS Homo sapiens
108 CDK2 1017
Affinity Capture-MS Homo sapiens
109 TPM1 7168
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
110 ABTB2 25841
Affinity Capture-MS Homo sapiens
111 SYNPO 11346
Affinity Capture-MS Homo sapiens
112 PRPF19 27339
Affinity Capture-MS Homo sapiens
113 MYC  
Affinity Capture-MS Homo sapiens
114 RPA3 6119
Affinity Capture-MS Homo sapiens
115 RPS14 6208
Cross-Linking-MS (XL-MS) Homo sapiens
116 MRFAP1  
Two-hybrid Homo sapiens
117 CFL1 1072
Cross-Linking-MS (XL-MS) Homo sapiens
118 AKT2 208
Affinity Capture-MS Homo sapiens
119 ACTN2 88
Co-fractionation Homo sapiens
120 DDB1 1642
Co-fractionation Homo sapiens
121 STMN1 3925
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
122 MYH7 4625
Co-fractionation Homo sapiens
123 MECOM 2122
Affinity Capture-MS Homo sapiens
124 SIK2  
Affinity Capture-MS Homo sapiens
125 AKT1 207
Affinity Capture-MS Homo sapiens
126 HIST1H1T 3010
Affinity Capture-MS Homo sapiens
127 C1orf43 25912
Affinity Capture-MS Homo sapiens
128 WAC  
Affinity Capture-MS Homo sapiens
129 TPM3 7170
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
130 YIPF1  
Affinity Capture-MS Homo sapiens
131 DDX46 9879
Co-fractionation Homo sapiens
132 HECTD1 25831
Co-fractionation Homo sapiens
133 TAF6 6878
Co-fractionation Homo sapiens
134 PDLIM7 9260
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
135 ZNF620  
Two-hybrid Homo sapiens
136 RBPJ 3516
Affinity Capture-MS Homo sapiens
137 PRKCSH 5589
Cross-Linking-MS (XL-MS) Homo sapiens
138 ZNF785  
Two-hybrid Homo sapiens
139 KIF14 9928
Affinity Capture-MS Homo sapiens
140 PKIG  
Affinity Capture-MS Homo sapiens
141 SKIL  
Two-hybrid Homo sapiens
142 HMGB1 3146
Co-fractionation Homo sapiens
143 SIRT2 22933
Affinity Capture-MS Homo sapiens
144 C6orf201  
Affinity Capture-MS Homo sapiens
145 SULT1A1 6817
Co-fractionation Homo sapiens
146 RPA1 6117
Affinity Capture-MS Homo sapiens
147 Myo1c 17913
Affinity Capture-MS Mus musculus
148 C17orf105  
Affinity Capture-MS Homo sapiens
149 CAPZA2 830
Affinity Capture-MS Homo sapiens
150 SNAPIN 23557
Two-hybrid Homo sapiens
151 ASPDH  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
152 DDX58 23586
Affinity Capture-RNA Homo sapiens
153 ZNF229  
Two-hybrid Homo sapiens
154 ZNF704  
Affinity Capture-MS Homo sapiens
155 Myh10 77579
Affinity Capture-MS Mus musculus
156 DYNC1H1 1778
Co-fractionation Homo sapiens
157 RPS28 6234
Cross-Linking-MS (XL-MS) Homo sapiens
158 Samm50  
Affinity Capture-MS Mus musculus
159 ABI2 10152
Two-hybrid Homo sapiens
160 DDX3X 1654
Co-fractionation Homo sapiens
161 LRRK2 120892
Affinity Capture-MS Homo sapiens
162 FLNA 2316
Affinity Capture-MS Homo sapiens
163 CCDC96  
Affinity Capture-MS Homo sapiens
164 RC3H1 149041
Affinity Capture-MS Homo sapiens
165 PSMB6 5694
Co-fractionation Homo sapiens
166 POTEB3 102724631
Affinity Capture-MS Homo sapiens
167 Tpm4  
Affinity Capture-MS Mus musculus
168 TIMM44 10469
Affinity Capture-MS Homo sapiens
169 TNNI1 7135
Co-fractionation Homo sapiens
View the network image/svg+xml
 Pathways in which TPM2 is involved
PathwayEvidenceSource
Muscle contraction TAS Reactome
Smooth Muscle Contraction TAS Reactome
Striated Muscle Contraction TAS Reactome





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