Gene description for HADHA
Gene name hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
Gene symbol HADHA
Other names/aliases ECHA
GBP
HADH
LCEH
LCHAD
MTPA
TP-ALPHA
Species Homo sapiens
 Database cross references - HADHA
ExoCarta ExoCarta_3030
Vesiclepedia VP_3030
Entrez Gene 3030
HGNC 4801
MIM 600890
UniProt P40939  
 HADHA identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Colorectal cancer cells 17956143    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Nasopharyngeal carcinoma cells 25857718    
Nasopharyngeal carcinoma cells 25857718    
Nasopharyngeal carcinoma cells 25857718    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
T lymphocytes 34108659    
 Gene ontology annotations for HADHA
Molecular Function
    fatty-acyl-CoA binding GO:0000062 IEA
    3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 TAS
    acetyl-CoA C-acetyltransferase activity GO:0003985 TAS
    enoyl-CoA hydratase activity GO:0004300 IBA
    protein binding GO:0005515 IPI
    long-chain-3-hydroxyacyl-CoA dehydrogenase activity GO:0016509 IBA
    3-hydroxyacyl-CoA dehydratase activity GO:0018812 IEA
    protein-containing complex binding GO:0044877 IEA
    NAD+ binding GO:0070403 IEA
Biological Process
    fatty acid beta-oxidation GO:0006635 IBA
    fatty acid beta-oxidation GO:0006635 IDA
    fatty acid beta-oxidation GO:0006635 IEA
    response to xenobiotic stimulus GO:0009410 IEA
    response to insulin GO:0032868 IEA
    cardiolipin acyl-chain remodeling GO:0035965 IDA
Subcellular Localization
    mitochondrion GO:0005739 HDA
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IDA
    mitochondrial inner membrane GO:0005743 IDA
    mitochondrial inner membrane GO:0005743 TAS
    mitochondrial fatty acid beta-oxidation multienzyme complex GO:0016507 IBA
    mitochondrial fatty acid beta-oxidation multienzyme complex GO:0016507 IPI
    mitochondrial nucleoid GO:0042645 IDA
 Experiment description of studies that identified HADHA in sEVs
1
Experiment ID 489
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 20
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
10
Experiment ID 407
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
11
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 405
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
16
Experiment ID 417
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 411
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
18
Experiment ID 488
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
19
Experiment ID 418
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 418
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 219
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25857718    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name Int J Cancer
Publication year 2015
Sample Nasopharyngeal carcinoma cells
Sample name C666-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.17-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
22
Experiment ID 220
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25857718    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name Int J Cancer
Publication year 2015
Sample Nasopharyngeal carcinoma cells
Sample name NP69
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.17-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
23
Experiment ID 221
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25857718    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name Int J Cancer
Publication year 2015
Sample Nasopharyngeal carcinoma cells
Sample name NP460
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.17-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
24
Experiment ID 413
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 211
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
26
Experiment ID 212
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
27
Experiment ID 406
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 415
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
30
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
31
Experiment ID 408
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 409
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
33
Experiment ID 416
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
34
Experiment ID 834
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
35
Experiment ID 835
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
36
Experiment ID 410
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for HADHA
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Mdm2  
Affinity Capture-MS Mus musculus
2 DNAJC11 55735
Affinity Capture-MS Homo sapiens
3 PRPF8 10594
Co-fractionation Homo sapiens
4 RIN3  
Affinity Capture-MS Homo sapiens
5 SKI 6497
Affinity Capture-MS Homo sapiens
6 TPM2 7169
Cross-Linking-MS (XL-MS) Homo sapiens
7 CDH5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 ACTC1 70
Affinity Capture-MS Homo sapiens
9 MTG2  
Proximity Label-MS Homo sapiens
10 C9orf78 51759
Affinity Capture-MS Homo sapiens
11 UBC 7316
Affinity Capture-MS Homo sapiens
12 PARK7 11315
Affinity Capture-MS Homo sapiens
13 SOX2  
Affinity Capture-MS Homo sapiens
14 CCDC90B  
Proximity Label-MS Homo sapiens
15 MAP1LC3B 81631
Affinity Capture-MS Homo sapiens
16 WDR76  
Affinity Capture-MS Homo sapiens
17 DDA1  
Affinity Capture-MS Homo sapiens
18 MRPL40 64976
Co-fractionation Homo sapiens
19 PMPCA 23203
Proximity Label-MS Homo sapiens
20 UBE2O 63893
Affinity Capture-MS Homo sapiens
21 COX7A2L 9167
Co-fractionation Homo sapiens
22 POU5F1  
Affinity Capture-MS Homo sapiens
23 ETFA 2108
Co-fractionation Homo sapiens
24 NDUFA3  
Co-fractionation Homo sapiens
25 MECP2 4204
Affinity Capture-MS Homo sapiens
26 PPP6R3 55291
Co-fractionation Homo sapiens
27 GPS1 2873
Co-fractionation Homo sapiens
28 VWA8 23078
Proximity Label-MS Homo sapiens
29 KIF21A 55605
Co-fractionation Homo sapiens
30 SLC25A3 5250
Co-fractionation Homo sapiens
31 KIF14 9928
Affinity Capture-MS Homo sapiens
32 AP1S2 8905
Co-fractionation Homo sapiens
33 MTCH2 23788
Co-fractionation Homo sapiens
34 ACOT9 23597
Co-fractionation Homo sapiens
35 MAP1B 4131
Co-fractionation Homo sapiens
36 TUFM 7284
Proximity Label-MS Homo sapiens
37 TTC19  
Affinity Capture-MS Homo sapiens
38 Srp72  
Affinity Capture-MS Mus musculus
39 YAP1 10413
Affinity Capture-MS Homo sapiens
40 CCDC109B 55013
Proximity Label-MS Homo sapiens
41 YWHAQ 10971
Reconstituted Complex Homo sapiens
42 ABCF1 23
Cross-Linking-MS (XL-MS) Homo sapiens
43 MTRF1L  
Proximity Label-MS Homo sapiens
44 DDX39B 7919
Cross-Linking-MS (XL-MS) Homo sapiens
45 SND1 27044
Co-fractionation Homo sapiens
46 VDAC2 7417
Co-fractionation Homo sapiens
47 GBAS 2631
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
48 SCARNA22  
Affinity Capture-RNA Homo sapiens
49 ANLN 54443
Affinity Capture-MS Homo sapiens
50 TMPO 7112
Affinity Capture-MS Homo sapiens
51 HADHB 3032
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
52 MRPS12  
Proximity Label-MS Homo sapiens
53 MTIF2 4528
Proximity Label-MS Homo sapiens
54 APOE 348
Co-fractionation Homo sapiens
55 SIRT7  
Affinity Capture-MS Homo sapiens
56 IQCB1  
Affinity Capture-MS Homo sapiens
57 CD274 29126
Affinity Capture-MS Homo sapiens
58 CUL3 8452
Affinity Capture-MS Homo sapiens
59 SDC2 6383
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
60 FN1 2335
Affinity Capture-MS Homo sapiens
61 ZNF782  
Co-fractionation Homo sapiens
62 CYP51A1 1595
Co-fractionation Homo sapiens
63 C12orf65  
Proximity Label-MS Homo sapiens
64 SAAL1 113174
Affinity Capture-MS Homo sapiens
65 KIF1BP 26128
Co-fractionation Homo sapiens
66 RPA3 6119
Proximity Label-MS Homo sapiens
67 COX6C 1345
Co-fractionation Homo sapiens
68 HSPA4 3308
Co-fractionation Homo sapiens
69 LAMA4 3910
Affinity Capture-MS Homo sapiens
70 COX2 4513
Co-fractionation Homo sapiens
71 NFATC2  
Affinity Capture-MS Homo sapiens
72 SCCPDH 51097
Co-fractionation Homo sapiens
73 U2SURP 23350
Co-fractionation Homo sapiens
74 AUH 549
Proximity Label-MS Homo sapiens
75 USP49 25862
Affinity Capture-MS Homo sapiens
76 PTPRD 5789
Affinity Capture-MS Homo sapiens
77 NRXN3 9369
Affinity Capture-MS Homo sapiens
78 WWOX 51741
Affinity Capture-MS Homo sapiens
79 COX5A 9377
Co-fractionation Homo sapiens
80 EPHX1 2052
Co-fractionation Homo sapiens
81 PTPN2 5771
Affinity Capture-MS Homo sapiens
82 HSP90AA1 3320
Co-fractionation Homo sapiens
83 SSBP1 6742
Proximity Label-MS Homo sapiens
84 AGRN 375790
Affinity Capture-MS Homo sapiens
85 CEBPA  
Protein-peptide Homo sapiens
86 MAP1LC3A 84557
Affinity Capture-MS Homo sapiens
87 DDX3X 1654
Affinity Capture-MS Homo sapiens
88 PLOD3 8985
Co-fractionation Homo sapiens
89 PCCB 5096
Co-fractionation Homo sapiens
90 RAB11A 8766
Co-fractionation Homo sapiens
91 SDC4 6385
Affinity Capture-MS Homo sapiens
92 CUL7 9820
Affinity Capture-MS Homo sapiens
93 VANGL1 81839
Affinity Capture-MS Homo sapiens
94 HNRNPH1 3187
Co-fractionation Homo sapiens
95 KIF23 9493
Affinity Capture-MS Homo sapiens
96 SPRTN  
Affinity Capture-MS Homo sapiens
97 VARS 7407
Co-fractionation Homo sapiens
98 BTF3 689
Affinity Capture-MS Homo sapiens
99 LGALS1 3956
Affinity Capture-MS Homo sapiens
100 ZFR 51663
Co-fractionation Homo sapiens
101 HSP90AB1 3326
Co-fractionation Homo sapiens
102 CAND1 55832
Affinity Capture-MS Homo sapiens
103 AAR2 25980
Co-fractionation Homo sapiens
104 NDUFA4 4697
Co-fractionation Homo sapiens
105 SETDB1  
Co-fractionation Homo sapiens
106 CPT1A 1374
Co-fractionation Homo sapiens
107 ATP5L 10632
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
108 B3GNT2 10678
Affinity Capture-MS Homo sapiens
109 OGDH 4967
Co-fractionation Homo sapiens
110 PRC1 9055
Affinity Capture-MS Homo sapiens
111 PPP6R1 22870
Affinity Capture-MS Homo sapiens
112 RAB5B 5869
Co-fractionation Homo sapiens
113 GPC6 10082
Affinity Capture-MS Homo sapiens
114 LEO1 123169
Affinity Capture-MS Homo sapiens
115 PHB 5245
Co-fractionation Homo sapiens
116 TOMM40 10452
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
117 ANKRD34C  
Co-fractionation Homo sapiens
118 C6orf203  
Proximity Label-MS Homo sapiens
119 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
120 NDUFA8 4702
Co-fractionation Homo sapiens
121 DHRS2 10202
Affinity Capture-MS Homo sapiens
122 SNRNP200 23020
Co-fractionation Homo sapiens
123 VRK1 7443
Affinity Capture-MS Homo sapiens
124 CFDP1  
Affinity Capture-MS Homo sapiens
125 GYS1 2997
Co-fractionation Homo sapiens
126 UQCRC1 7384
Co-fractionation Homo sapiens
127 PREB 10113
Co-fractionation Homo sapiens
128 TGFBR3 7049
Affinity Capture-MS Homo sapiens
129 AGPS 8540
Co-fractionation Homo sapiens
130 PPM1G 5496
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
131 Ksr1  
Affinity Capture-MS Mus musculus
132 PER2  
Proximity Label-MS Homo sapiens
133 CXCR4 7852
Affinity Capture-MS Homo sapiens
134 AIFM1 9131
Proximity Label-MS Homo sapiens
135 CANX 821
Co-fractionation Homo sapiens
136 ATL3 25923
Co-fractionation Homo sapiens
137 ICAM1 3383
Co-fractionation Homo sapiens
138 SLC25A51  
Proximity Label-MS Homo sapiens
139 MTIF3  
Proximity Label-MS Homo sapiens
140 TUBB4B 10383
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
141 ATP5F1 515
Co-fractionation Homo sapiens
142 RMND1 55005
Proximity Label-MS Homo sapiens
143 HSD17B10 3028
Two-hybrid Homo sapiens
144 FTH1 2495
Co-fractionation Homo sapiens
145 NAF1  
Affinity Capture-MS Homo sapiens
146 RIPK4  
Affinity Capture-MS Homo sapiens
147 CDK2 1017
Affinity Capture-MS Homo sapiens
148 CNR2  
Affinity Capture-MS Homo sapiens
149 BAG1 573
Affinity Capture-MS Homo sapiens
150 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
151 ACAD9 28976
Proximity Label-MS Homo sapiens
152 DDB1 1642
Affinity Capture-MS Homo sapiens
153 DDRGK1 65992
Affinity Capture-MS Homo sapiens
154 OSBPL8 114882
Affinity Capture-MS Homo sapiens
155 MCUR1 63933
Proximity Label-MS Homo sapiens
156 CLPP 8192
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
157 CS 1431
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
158 C17orf80 55028
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
159 RC3H1 149041
Affinity Capture-MS Homo sapiens
160 PARP1 142
Cross-Linking-MS (XL-MS) Homo sapiens
161 MAX  
Co-fractionation Homo sapiens
162 BCKDHA 593
Co-fractionation Homo sapiens
163 CAPZA2 830
Affinity Capture-MS Homo sapiens
164 SQSTM1 8878
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
165 Numb  
Affinity Capture-MS Mus musculus
166 ATG101  
Affinity Capture-MS Homo sapiens
167 COX8A  
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
168 SHMT2 6472
Co-fractionation Homo sapiens
169 ESR1  
Affinity Capture-MS Homo sapiens
170 GFM1 85476
Proximity Label-MS Homo sapiens
171 UBR4 23352
Co-fractionation Homo sapiens
172 C1QBP 708
Proximity Label-MS Homo sapiens
173 ATP5C1 509
Co-fractionation Homo sapiens
174 MYC  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
175 YBEY  
Affinity Capture-MS Homo sapiens
176 TOMM5  
Co-fractionation Homo sapiens
177 GABARAPL1 23710
Affinity Capture-MS Homo sapiens
178 COL6A1 1291
Co-fractionation Homo sapiens
179 RAB1A 5861
Co-fractionation Homo sapiens
180 NDUFS1 4719
Co-fractionation Homo sapiens
181 GPC2  
Affinity Capture-MS Homo sapiens
182 GPC1 2817
Affinity Capture-MS Homo sapiens
183 RPS19 6223
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
184 NEFM 4741
Cross-Linking-MS (XL-MS) Homo sapiens
185 LRPPRC 10128
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
186 CAPZB 832
Affinity Capture-MS Homo sapiens
187 MGST1 4257
Co-fractionation Homo sapiens
188 HEATR3 55027
Affinity Capture-MS Homo sapiens
189 NDUFS3 4722
Co-fractionation Homo sapiens
190 NDUFB8 4714
Co-fractionation Homo sapiens
191 MCM2 4171
Affinity Capture-MS Homo sapiens
192 KPNA3 3839
Co-fractionation Homo sapiens
193 HINT2 84681
Proximity Label-MS Homo sapiens
194 AASS  
Co-fractionation Homo sapiens
195 C20orf24  
Co-fractionation Homo sapiens
196 NDUFV1 4723
Co-fractionation Homo sapiens
197 PRDX4 10549
Co-fractionation Homo sapiens
198 CALR 811
Co-fractionation Homo sapiens
199 TFCP2 7024
Affinity Capture-MS Homo sapiens
200 UQCRQ 27089
Co-fractionation Homo sapiens
201 NDUFS5 4725
Co-fractionation Homo sapiens
202 MTERF3  
Proximity Label-MS Homo sapiens
203 MDH2 4191
Proximity Label-MS Homo sapiens
204 PTGES2 80142
Co-fractionation Homo sapiens
205 ATP5A1 498
Co-fractionation Homo sapiens
206 P4HA1 5033
Co-fractionation Homo sapiens
207 CD74 972
Two-hybrid Homo sapiens
208 PARK2  
Affinity Capture-MS Homo sapiens
209 RTF1 23168
Affinity Capture-MS Homo sapiens
210 ABCF2 10061
Two-hybrid Homo sapiens
211 CHMP4B 128866
Affinity Capture-MS Homo sapiens
212 SLC25A20 788
Co-fractionation Homo sapiens
213 NTRK1 4914
Affinity Capture-MS Homo sapiens
214 OCIAD2 132299
Co-fractionation Homo sapiens
215 ACTB 60
Co-fractionation Homo sapiens
216 COPS3 8533
Co-fractionation Homo sapiens
217 MRPL11 65003
Proximity Label-MS Homo sapiens
218 HDAC5 10014
Affinity Capture-MS Homo sapiens
219 IPO9 55705
Affinity Capture-MS Homo sapiens
220 CA9 768
Affinity Capture-MS Homo sapiens
221 SDC3  
Affinity Capture-MS Homo sapiens
222 GPC4 2239
Affinity Capture-MS Homo sapiens
223 CDC73  
Affinity Capture-MS Homo sapiens
224 TRMT10C 54931
Co-fractionation Homo sapiens
225 ECT2 1894
Affinity Capture-MS Homo sapiens
226 EEF2 1938
Co-fractionation Homo sapiens
227 NR3C1 2908
Affinity Capture-MS Homo sapiens
228 CORO1C 23603
Co-fractionation Homo sapiens
229 SOX15  
Affinity Capture-MS Homo sapiens
230 GNA11 2767
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
231 GARNL3  
Cross-Linking-MS (XL-MS) Homo sapiens
232 EMC2 9694
Co-fractionation Homo sapiens
233 CYC1 1537
Co-fractionation Homo sapiens
234 Kctd5  
Affinity Capture-MS Mus musculus
235 MSN 4478
Co-fractionation Homo sapiens
236 HSPA9 3313
Co-fractionation Homo sapiens
237 METTL15  
Proximity Label-MS Homo sapiens
238 NDUFS2 4720
Co-fractionation Homo sapiens
239 IMMT 10989
Co-fractionation Homo sapiens
240 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
241 PHB2 11331
Co-fractionation Homo sapiens
242 TSFM 10102
Proximity Label-MS Homo sapiens
243 RPL6 6128
Cross-Linking-MS (XL-MS) Homo sapiens
244 ICT1 3396
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
245 PIN1 5300
Reconstituted Complex Homo sapiens
246 PDHA1 5160
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
247 GABARAPL2 11345
Affinity Capture-MS Homo sapiens
248 DDX58 23586
Affinity Capture-RNA Homo sapiens
249 GNG5 2787
Co-fractionation Homo sapiens
250 NDUFS8 4728
Co-fractionation Homo sapiens
251 TBRG4 9238
Proximity Label-MS Homo sapiens
252 AARS2  
Proximity Label-MS Homo sapiens
253 RAB7A 7879
Co-fractionation Homo sapiens
254 GPC3 2719
Affinity Capture-MS Homo sapiens
255 CIT 11113
Affinity Capture-MS Homo sapiens
256 SPG20 23111
Affinity Capture-MS Homo sapiens
257 SERBP1 26135
Affinity Capture-MS Homo sapiens
258 STT3B 201595
Co-fractionation Homo sapiens
259 COX7C 1350
Co-fractionation Homo sapiens
260 CD44 960
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
261 VDAC3 7419
Co-fractionation Homo sapiens
262 TFAM 7019
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
263 MGST3 4259
Co-fractionation Homo sapiens
264 EP300 2033
Affinity Capture-MS Homo sapiens
265 UBE2H 7328
Affinity Capture-MS Homo sapiens
266 Edc4  
Affinity Capture-MS Mus musculus
267 GNAO1 2775
Co-fractionation Homo sapiens
268 TNPO1 3842
Co-fractionation Homo sapiens
269 CDH8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
270 TMEFF1  
Affinity Capture-MS Homo sapiens
271 KPNB1 3837
Co-fractionation Homo sapiens
272 TRUB2  
Proximity Label-MS Homo sapiens
273 USP9X 8239
Co-fractionation Homo sapiens
274 ETFB 2109
Cross-Linking-MS (XL-MS) Homo sapiens
275 DNAJC25 548645
Affinity Capture-MS Homo sapiens
276 ZBTB1  
Affinity Capture-MS Homo sapiens
277 DNAJC15  
Affinity Capture-MS Homo sapiens
278 MTRF1  
Proximity Label-MS Homo sapiens
279 USP36  
Affinity Capture-MS Homo sapiens
280 KIAA1429 25962
Affinity Capture-MS Homo sapiens
281 KIF20A 10112
Affinity Capture-MS Homo sapiens
282 PRDX3 10935
Co-fractionation Homo sapiens
283 GLG1 2734
Affinity Capture-MS Homo sapiens
284 ATXN2L 11273
Two-hybrid Homo sapiens
285 CYB5R1 51706
Co-fractionation Homo sapiens
286 FBXW7  
Affinity Capture-MS Homo sapiens
287 COA3 28958
Co-fractionation Homo sapiens
288 MRPS26 64949
Proximity Label-MS Homo sapiens
289 ATP5O 539
Co-fractionation Homo sapiens
290 EXD2  
Proximity Label-MS Homo sapiens
291 VAT1 10493
Cross-Linking-MS (XL-MS) Homo sapiens
292 CASK 8573
Affinity Capture-MS Homo sapiens
293 USP22 23326
Affinity Capture-MS Homo sapiens
294 STOML2 30968
Co-fractionation Homo sapiens
295 SRP9 6726
Affinity Capture-MS Homo sapiens
296 EMD 2010
Affinity Capture-MS Homo sapiens
297 ARRDC1 92714
Affinity Capture-MS Homo sapiens
298 PSMD4 5710
Affinity Capture-MS Homo sapiens
299 HSP90B1 7184
Co-fractionation Homo sapiens
300 ATF2  
Affinity Capture-MS Homo sapiens
301 RELL2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
302 HSCB 150274
Proximity Label-MS Homo sapiens
303 USMG5 84833
Co-fractionation Homo sapiens
304 VCP 7415
Affinity Capture-MS Homo sapiens
305 SRF  
Affinity Capture-MS Homo sapiens
306 PLEK2 26499
Cross-Linking-MS (XL-MS) Homo sapiens
307 BTK 695
Affinity Capture-MS Homo sapiens
308 H2AFY 9555
Co-fractionation Homo sapiens
309 NIPSNAP1 8508
Co-fractionation Homo sapiens
310 ATP5B 506
Co-fractionation Homo sapiens
311 COX4I1 1327
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
312 NID2 22795
Affinity Capture-MS Homo sapiens
313 COPS2 9318
Co-fractionation Homo sapiens
314 MRRF  
Proximity Label-MS Homo sapiens
315 NR4A1  
Two-hybrid Homo sapiens
316 SDC1 6382
Affinity Capture-MS Homo sapiens
317 NDUFA9 4704
Co-fractionation Homo sapiens
318 LETM1 3954
Co-fractionation Homo sapiens
319 UQCRC2 7385
Co-fractionation Homo sapiens
320 CYB5R3 1727
Co-fractionation Homo sapiens
321 ADNP 23394
Co-fractionation Homo sapiens
322 PMPCB 9512
Proximity Label-MS Homo sapiens
323 IL7R  
Affinity Capture-MS Homo sapiens
324 ASPH 444
Co-fractionation Homo sapiens
325 ATP1B1 481
Co-fractionation Homo sapiens
326 VDAC1 7416
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
327 FARP1 10160
Affinity Capture-MS Homo sapiens
328 CCDC8  
Affinity Capture-MS Homo sapiens
329 Cbx1  
Affinity Capture-MS Mus musculus
330 NRP1 8829
Affinity Capture-MS Homo sapiens
331 DNAJC19 131118
Affinity Capture-MS Homo sapiens
332 C11orf58  
Co-fractionation Homo sapiens
333 TUBG1 7283
Affinity Capture-MS Homo sapiens
334 CCDC50 152137
Affinity Capture-MS Homo sapiens
335 WBP11  
Co-fractionation Homo sapiens
336 ZNF746  
Affinity Capture-MS Homo sapiens
337 B3GALT6 126792
Affinity Capture-MS Homo sapiens
338 TPTE  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
339 NDUFS7 374291
Co-fractionation Homo sapiens
340 PDHB 5162
Co-fractionation Homo sapiens
341 C21orf33  
Proximity Label-MS Homo sapiens
342 CUL9  
Affinity Capture-MS Homo sapiens
343 SFXN1 94081
Co-fractionation Homo sapiens
344 HMGCLL1  
Co-fractionation Homo sapiens
345 TRIP4 9325
Affinity Capture-MS Homo sapiens
346 PINK1  
Affinity Capture-MS Homo sapiens
347 COX7A2 1347
Co-fractionation Homo sapiens
348 GRSF1 2926
Affinity Capture-MS Homo sapiens
349 MYL12A 10627
Co-fractionation Homo sapiens
350 DNAJC1 64215
Affinity Capture-MS Homo sapiens
351 HNRNPU 3192
Cross-Linking-MS (XL-MS) Homo sapiens
352 C9orf72  
Affinity Capture-MS Homo sapiens
353 METTL17  
Proximity Label-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here