ExoCarta: Gene summary

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Gene description for ICT1
Gene name	immature colon carcinoma transcript 1
Gene symbol	ICT1
Other names/aliases	DS-1 DS1 MRP-L58
Species	Homo sapiens
Database cross references - ICT1
ExoCarta	ExoCarta_3396
Vesiclepedia	VP_3396
Entrez Gene	3396
HGNC	5359
MIM	603000
UniProt	Q14197
ICT1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells	36408942
Bone marrow mesenchymal stem cells	36408942
Bone marrow mesenchymal stem cells	36408942
Bone marrow mesenchymal stem cells	36408942

Gene ontology annotations for ICT1

Molecular Function
	aminoacyl-tRNA hydrolase activity	GO:0004045	IBA
	aminoacyl-tRNA hydrolase activity	GO:0004045	IDA
	translation release factor activity, codon nonspecific	GO:0016150	IBA
	translation release factor activity, codon nonspecific	GO:0016150	IDA
Biological Process
	mitochondrial translation	GO:0032543	NAS
	mitochondrial translational termination	GO:0070126	IBA
	mitochondrial translational termination	GO:0070126	IDA
	rescue of stalled ribosome	GO:0072344	IDA
Subcellular Localization
	nucleoplasm	GO:0005654	IDA
	mitochondrion	GO:0005739	HTP
	mitochondrion	GO:0005739	IDA
	mitochondrial inner membrane	GO:0005743	NAS
	mitochondrial inner membrane	GO:0005743	TAS
	mitochondrial matrix	GO:0005759	TAS
	mitochondrial large ribosomal subunit	GO:0005762	IBA
	mitochondrial large ribosomal subunit	GO:0005762	IDA
	mitochondrial large ribosomal subunit	GO:0005762	NAS
	plasma membrane	GO:0005886	IDA

Experiment description of studies that identified ICT1 in sEVs

Experiment ID

489

MISEV standards
✔	Biophysical techniques
✔	Enriched markers
✔	Negative markers
✔	Particle analysis

Identified molecule

Protein

Identification method

Mass spectrometry

PubMed ID

36408942

Organism

Rattus norvegicus

Experiment description

Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells

Authors

"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."

Journal name

Proteomics

Publication year

2023

Sample

Bone marrow mesenchymal stem cells

Sample name

BMSC - Passage 6

Isolation/purification methods

Differential centrifugation
Filtration
Ultracentrifugation

Flotation density

Molecules identified in the study

Protein

Methods used in the study

Western blotting
Mass spectometry

Experiment ID

490

MISEV standards
✔	Biophysical techniques
✔	Enriched markers
✔	Negative markers
✔	Particle analysis

Identified molecule

Protein

Identification method

Mass spectrometry

PubMed ID

36408942

Organism

Rattus norvegicus

Experiment description

Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells

Authors

"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."

Journal name

Proteomics

Publication year

2023

Sample

Bone marrow mesenchymal stem cells

Sample name

BMSC - Passage 7

Isolation/purification methods

Differential centrifugation
Filtration
Ultracentrifugation

Flotation density

Molecules identified in the study

Protein

Methods used in the study

Western blotting
Mass spectometry

Experiment ID

491

MISEV standards
✔	Biophysical techniques
✔	Enriched markers
✔	Negative markers
✔	Particle analysis

Identified molecule

Protein

Identification method

Mass spectrometry

PubMed ID

36408942

Organism

Rattus norvegicus

Experiment description

Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells

Authors

"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."

Journal name

Proteomics

Publication year

2023

Sample

Bone marrow mesenchymal stem cells

Sample name

BMSC - Passage 8

Isolation/purification methods

Differential centrifugation
Filtration
Ultracentrifugation

Flotation density

Molecules identified in the study

Protein

Methods used in the study

Western blotting
Mass spectometry

Experiment ID

492

MISEV standards
✔	Biophysical techniques
✔	Enriched markers
✔	Negative markers
✔	Particle analysis

Identified molecule

Protein

Identification method

Mass spectrometry

PubMed ID

36408942

Organism

Rattus norvegicus

Experiment description

Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells

Authors

"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."

Journal name

Proteomics

Publication year

2023

Sample

Bone marrow mesenchymal stem cells

Sample name

BMSC - Passage 9

Isolation/purification methods

Differential centrifugation
Filtration
Ultracentrifugation

Flotation density

Molecules identified in the study

Protein

Methods used in the study

Western blotting
Mass spectometry

Protein-protein interactions for ICT1

Protein Interactor

ExoCarta ID

Identification method

PubMed

Species

SLC25A13

10165

Affinity Capture-MS

Homo sapiens

UQCRFS1

7386

Co-fractionation

Homo sapiens

SLC25A18

Affinity Capture-MS

Homo sapiens

MRPL33

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

ACOT9

23597

Affinity Capture-MS

Homo sapiens

MTG2

Proximity Label-MS

Homo sapiens

MRPL24

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

MRPL27

51264

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

SLC25A1

6576

Affinity Capture-MS

Homo sapiens

MRPS18C

Proximity Label-MS

Homo sapiens

MCU

90550

Affinity Capture-MS

Homo sapiens

PMPCA

23203

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

CDH2

1000

Co-fractionation

Homo sapiens

PUSL1

Affinity Capture-MS

Homo sapiens

ETFA

2108

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

POLRMT

5442

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

PTCD1

26024

Affinity Capture-MS

Homo sapiens

BCS1L

617

Proximity Label-MS

Homo sapiens

VWA8

23078

Proximity Label-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

MRPL47

57129

Affinity Capture-MS		Homo sapiens
Co-fractionation		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

RPL19

6143

Affinity Capture-MS

Homo sapiens

SLC25A3

5250

Affinity Capture-MS

Homo sapiens

HSPA9

3313

Affinity Capture-MS

Homo sapiens

PGAM5

192111

Affinity Capture-MS

Homo sapiens

ACADVL

Affinity Capture-MS

Homo sapiens

SRSF3

6428

Co-fractionation

Homo sapiens

YBX2

51087

Affinity Capture-MS

Homo sapiens

TUFM

7284

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

SYNJ2BP

55333

Co-fractionation

Homo sapiens

RBMS2

5939

Affinity Capture-MS

Homo sapiens

MRPS6

Affinity Capture-MS		Homo sapiens
Affinity Capture-Western		Homo sapiens
Proximity Label-MS		Homo sapiens

CCDC109B

55013

Proximity Label-MS

Homo sapiens

SYNCRIP

10492

Co-fractionation

Homo sapiens

CYC1

1537

Co-fractionation

Homo sapiens

DBT

1629

Proximity Label-MS

Homo sapiens

MTRF1L

Proximity Label-MS

Homo sapiens

DDX39B

7919

Proximity Label-MS

Homo sapiens

SLC25A5

292

Affinity Capture-MS

Homo sapiens

MRPL41

64975

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Co-fractionation		Homo sapiens
Proximity Label-MS		Homo sapiens

MRPL14

64928

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

RARS2

Proximity Label-MS

Homo sapiens

WBSCR16

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

HADHA

3030

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

MRPS12

Proximity Label-MS

Homo sapiens

MTIF2

4528

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

MCCC2

64087

Affinity Capture-MS

Homo sapiens

NDUFA13

51079

Affinity Capture-MS

Homo sapiens

SDHA

6389

Affinity Capture-MS

Homo sapiens

MRPL16

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

MRPL3

Affinity Capture-MS		Homo sapiens
Co-fractionation		Homo sapiens
Affinity Capture-Western		Homo sapiens
Affinity Capture-Western		Homo sapiens
Co-fractionation		Homo sapiens
Proximity Label-MS		Homo sapiens

FAHD1

81889

Affinity Capture-MS

Homo sapiens

GADD45GIP1

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

VARS2

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

C12orf65

Proximity Label-MS

Homo sapiens

HNRNPR

10236

Proximity Label-MS

Homo sapiens

MTG1

Affinity Capture-MS

Homo sapiens

DLST

1743

Proximity Label-MS

Homo sapiens

RPL27A

6157

Affinity Capture-MS

Homo sapiens

AUH

549

Proximity Label-MS

Homo sapiens

COX2

4513

Affinity Capture-MS

Homo sapiens

DLAT

1737

Proximity Label-MS

Homo sapiens

MRPL18

29074

Co-fractionation		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens
Cross-Linking-MS (XL-MS)		Homo sapiens

Fbxw11

Affinity Capture-MS

Mus musculus

YBX1

4904

Affinity Capture-MS

Homo sapiens

DNAJC28

Proximity Label-MS

Homo sapiens

GLS

2744

Proximity Label-MS

Homo sapiens

CLPX

10845

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

COQ5

Proximity Label-MS

Homo sapiens

NME4

4833

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

MTERF1

Affinity Capture-MS

Homo sapiens

CLPTM1

1209

Co-fractionation

Homo sapiens

RRP1

8568

Proximity Label-MS

Homo sapiens

ATP5B

506

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

SSBP1

6742

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

OAT

4942

Affinity Capture-MS

Homo sapiens

NIPSNAP1

8508

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

LARS2

23395

Proximity Label-MS

Homo sapiens

PARS2

25973

Affinity Capture-MS

Homo sapiens

ACOT1

641371

Proximity Label-MS

Homo sapiens

FECH

2235

Proximity Label-MS

Homo sapiens

THNSL1

79896

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

MRPS16

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

ATXN7L3

Affinity Capture-MS

Homo sapiens

MRPL55

Affinity Capture-MS		Homo sapiens
Co-fractionation		Homo sapiens
Proximity Label-MS		Homo sapiens

POLG

Proximity Label-MS

Homo sapiens

HNRNPL

3191

Proximity Label-MS

Homo sapiens

MRPL28

10573

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

LUC7L

55692

Proximity Label-MS

Homo sapiens

NDUFS6

Proximity Label-MS

Homo sapiens

AFG3L2

10939

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

H1FNT

Affinity Capture-MS

Homo sapiens

MRPL48

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

ATP5J2-PTCD1

Proximity Label-MS

Homo sapiens

GTPBP10

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

MTPAP

55149

Proximity Label-MS

Homo sapiens

ALDH2

217

Affinity Capture-MS

Homo sapiens

NDUFB5

4711

Co-fractionation

Homo sapiens

CHCHD1

Affinity Capture-MS

Homo sapiens

RPL14

9045

Co-fractionation

Homo sapiens

100

MRPL50

54534

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

101

MUT

4594

Affinity Capture-MS

Homo sapiens

102

MRPL49

740

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

103

MRPL44

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

104

NDUFS2

4720

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

105

ATP5L

10632

Affinity Capture-MS

Homo sapiens

106

RPS18

6222

Co-fractionation

Homo sapiens

107

OGDH

4967

Proximity Label-MS

Homo sapiens

108

HINT2

84681

Proximity Label-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

109

HARS2

23438

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

110

MRPS23

51649

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

111

NDUFA5

4698

Proximity Label-MS

Homo sapiens

112

MALSU1

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

113

ERAL1

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

114

PHB

5245

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

115

NDUFV3

4731

Proximity Label-MS

Homo sapiens

116

MRPS7

51081

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

117

PMPCB

9512

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

118

TACO1

Proximity Label-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

119

FASTKD2

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

120

HK1

3098

Affinity Capture-MS

Homo sapiens

121

NNT

23530

Proximity Label-MS

Homo sapiens

122

SLC25A10

1468

Affinity Capture-MS

Homo sapiens

123

C6orf203

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

124

MRPL45

84311

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

125

RPL4

6124

Co-fractionation

Homo sapiens

126

PPT2

Co-fractionation

Homo sapiens

127

ATPAF1

Proximity Label-MS

Homo sapiens

128

ALDH18A1

5832

Affinity Capture-MS

Homo sapiens

129

MRPL51

51258

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Co-fractionation		Homo sapiens
Proximity Label-MS		Homo sapiens

130

POLDIP2

26073

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

131

NDUFA2

4695

Co-fractionation		Homo sapiens
Proximity Label-MS		Homo sapiens

132

UQCRC1

7384

Affinity Capture-MS

Homo sapiens

133

AARS2

Proximity Label-MS

Homo sapiens

134

CYLD

Affinity Capture-MS

Homo sapiens

135

ABCB7

Affinity Capture-MS

Homo sapiens

136

NDUFAF1

Proximity Label-MS

Homo sapiens

137

MRM1

Affinity Capture-MS

Homo sapiens

138

IBA57

Proximity Label-MS

Homo sapiens

139

MRPS35

60488

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

140

PCCB

5096

Affinity Capture-MS

Homo sapiens

141

MRPS11

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

142

MTIF3

Proximity Label-MS

Homo sapiens

143

MRPL9

65005

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

144

ATP5F1

515

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

145

HSD17B10

3028

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

146

MYC

Dosage Lethality		Homo sapiens
Affinity Capture-MS		Homo sapiens

147

HNRNPAB

3182

Proximity Label-MS

Homo sapiens

148

MRPS17

51373

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

149

NDUFV2

4729

Proximity Label-MS

Homo sapiens

150

RPL26

6154

Affinity Capture-MS

Homo sapiens

151

PPIF

10105

Proximity Label-MS

Homo sapiens

152

RPL13

6137

Affinity Capture-MS

Homo sapiens

153

1431

Proximity Label-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

154

C17orf80

55028

Proximity Label-MS

Homo sapiens

155

WARS2

Proximity Label-MS

Homo sapiens

156

CALU

813

Co-fractionation

Homo sapiens

157

TRMT61B

Proximity Label-MS

Homo sapiens

158

MRPS15

Affinity Capture-MS

Homo sapiens

159

SHMT2

6472

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

160

HNRNPK

3190

Proximity Label-MS

Homo sapiens

161

ME2

4200

Affinity Capture-MS

Homo sapiens

162

GFM1

85476

Proximity Label-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

163

TEFM

Proximity Label-MS

Homo sapiens

164

DDX28

Co-fractionation		Homo sapiens
Affinity Capture-MS		Homo sapiens

165

TIMM44

10469

Proximity Label-MS

Homo sapiens

166

C1QBP

708

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

167

ATP5C1

509

Affinity Capture-MS

Homo sapiens

168

ALDH1L2

160428

Affinity Capture-MS

Homo sapiens

169

MRPS9

64965

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

170

MRPS27

23107

Affinity Capture-Western		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

171

SLIRP

81892

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

172

NDUFS1

4719

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

173

SIKE1

Affinity Capture-MS

Homo sapiens

174

MRPL30

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

175

MRPL17

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

176

ANGEL2

90806

Proximity Label-MS

Homo sapiens

177

ISCA1

Affinity Capture-MS

Homo sapiens

178

NOA1

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

179

PYCR1

5831

Proximity Label-MS

Homo sapiens

180

SYNE2

23224

Co-fractionation

Homo sapiens

181

GATB

Proximity Label-MS

Homo sapiens

182

CARS2

79587

Proximity Label-MS

Homo sapiens

183

LRPPRC

10128

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

184

ACAD9

28976

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

185

NDUFS3

4722

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

186

SARS2

54938

Affinity Capture-MS

Homo sapiens

187

YARS2

Affinity Capture-MS

Homo sapiens

188

SUPV3L1

6832

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

189

AASS

Affinity Capture-MS

Homo sapiens

190

MRPL39

54148

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Co-fractionation		Homo sapiens
Co-fractionation		Homo sapiens
Proximity Label-MS		Homo sapiens

191

NDUFV1

4723

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

192

PRDX4

10549

Affinity Capture-MS

Homo sapiens

193

ADCK3

Affinity Capture-MS

Homo sapiens

194

MRPL4

51073

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Co-fractionation		Homo sapiens
Proximity Label-MS		Homo sapiens

195

MTERF3

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

196

LIN28A

Affinity Capture-MS

Homo sapiens

197

MDH2

4191

Proximity Label-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

198

ALAS1

Proximity Label-MS

Homo sapiens

199

EIF2AK2

5610

Proximity Label-MS

Homo sapiens

200

ATAD3B

83858

Affinity Capture-MS

Homo sapiens

201

MRPS25

64432

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

202

ATP5A1

498

Affinity Capture-MS

Homo sapiens

203

FASTKD5

Proximity Label-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

204

NDUFB7

4713

Co-fractionation

Homo sapiens

205

CENPV

201161

Proximity Label-MS

Homo sapiens

206

PAM16

Proximity Label-MS

Homo sapiens

207

KIAA0391

Proximity Label-MS

Homo sapiens

208

MRPL11

65003

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

209

HNRNPA3

220988

Proximity Label-MS

Homo sapiens

210

TMEM70

Proximity Label-MS

Homo sapiens

211

MRPL2

51069

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

212

HNRNPDL

9987

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

213

ECH1

1891

Affinity Capture-MS

Homo sapiens

214

ACAT1

Proximity Label-MS

Homo sapiens

215

MRPL40

64976

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

216

SLC25A12

8604

Affinity Capture-MS

Homo sapiens

217

TRMT10C

54931

Proximity Label-MS

Homo sapiens

218

PNPT1

87178

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

219

CDK5RAP1

Proximity Label-MS

Homo sapiens

220

MRPS14

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

221

HNRNPA1

3178

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

222

DHX30

22907

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

223

HNRNPUL1

11100

Proximity Label-MS

Homo sapiens

224

AP2M1

1173

Affinity Capture-MS

Homo sapiens

225

MRPS28

Affinity Capture-MS		Homo sapiens
Co-fractionation		Homo sapiens
Proximity Label-MS		Homo sapiens

226

CECR5

27440

Affinity Capture-MS

Homo sapiens

227

MRPL19

9801

Co-fractionation		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

228

MRPL37

51253

Affinity Capture-MS		Homo sapiens
Co-fractionation		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

229

HSDL2

84263

Proximity Label-MS

Homo sapiens

230

TOP1

7150

Affinity Capture-MS

Homo sapiens

231

MRPS36

92259

Proximity Label-MS

Homo sapiens

232

HSPD1

3329

Affinity Capture-MS

Homo sapiens

233

MRPL38

Proximity Label-MS

Homo sapiens

234

PUS1

80324

Affinity Capture-MS

Homo sapiens

235

METTL15

Proximity Label-MS

Homo sapiens

236

FLOT1

10211

Co-fractionation

Homo sapiens

237

IMMT

10989

Affinity Capture-MS

Homo sapiens

238

DDX50

79009

Proximity Label-MS

Homo sapiens

239

RPL37

6167

Affinity Capture-MS

Homo sapiens

240

PLEKHA4

57664

Affinity Capture-MS

Homo sapiens

241

PHB2

11331

Affinity Capture-MS

Homo sapiens

242

TSFM

10102

Proximity Label-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

243

SLC25A6

293

Affinity Capture-MS

Homo sapiens

244

PDK3

5165

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

245

NDUFAF2

Proximity Label-MS

Homo sapiens

246

RPL6

6128

Affinity Capture-MS

Homo sapiens

247

LONP1

9361

Affinity Capture-MS

Homo sapiens

248

MRPL53

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

249

PDHA1

5160

Proximity Label-MS

Homo sapiens

250

ERLIN2

11160

Affinity Capture-MS

Homo sapiens

251

NDUFA12

55967

Proximity Label-MS

Homo sapiens

252

GRPEL1

80273

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

253

MRPS10

55173

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

254

MTHFD1

4522

Co-fractionation

Homo sapiens

255

ERGIC1

57222

Co-fractionation

Homo sapiens

256

GUF1

Proximity Label-MS

Homo sapiens

257

NDUFS8

4728

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

258

MRPS18B

28973

Affinity Capture-MS		Homo sapiens
Affinity Capture-Western		Homo sapiens
Proximity Label-MS		Homo sapiens

259

TBRG4

9238

Proximity Label-MS

Homo sapiens

260

RNMTL1

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

261

MGME1

Proximity Label-MS

Homo sapiens

262

RPUSD3

Affinity Capture-MS

Homo sapiens

263

LAMB3

3914

Affinity Capture-MS

Homo sapiens

264

VDAC3

7419

Affinity Capture-MS

Homo sapiens

265

MRPS22

56945

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

266

FLAD1

80308

Affinity Capture-MS

Homo sapiens

267

PRDX3

10935

Proximity Label-MS

Homo sapiens

268

IGF2BP2

10644

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

269

IARS2

55699

Proximity Label-MS

Homo sapiens

270

UBE2H

7328

Affinity Capture-MS

Homo sapiens

271

RBMS3

Affinity Capture-MS

Homo sapiens

272

TRUB2

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

273

NGRN

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

274

RPL10

6134

Affinity Capture-MS

Homo sapiens

275

MRPL10

124995

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Co-fractionation		Homo sapiens
Proximity Label-MS		Homo sapiens

276

ETFB

2109

Proximity Label-MS

Homo sapiens

277

KARS

3735

Affinity Capture-MS

Homo sapiens

278

ECI1

1632

Affinity Capture-MS

Homo sapiens

279

MRPL52

Affinity Capture-MS		Homo sapiens
Co-fractionation		Homo sapiens
Proximity Label-MS		Homo sapiens

280

RPUSD4

84881

Proximity Label-MS

Homo sapiens

281

DNAJC15

Proximity Label-MS

Homo sapiens

282

MTRF1

Proximity Label-MS

Homo sapiens

283

APP

351

Reconstituted Complex

Homo sapiens

284

ILF2

3608

Co-fractionation

Homo sapiens

285

HADH

3033

Proximity Label-MS

Homo sapiens

286

MRPL20

55052

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

287

TFAM

7019

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

288

NDUFA7

4701

Proximity Label-MS

Homo sapiens

289

MRPL23

6150

Affinity Capture-MS		Homo sapiens
Co-fractionation		Homo sapiens
Proximity Label-MS		Homo sapiens

290

MRPS5

64969

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

291

C8orf82

Proximity Label-MS

Homo sapiens

292

MRPS24

64951

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

293

MRPL12

6182

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Co-fractionation		Homo sapiens
Affinity Capture-Western		Homo sapiens
Affinity Capture-Western		Homo sapiens
Co-fractionation		Homo sapiens
Proximity Label-MS		Homo sapiens

294

HMGA1

3159

Proximity Label-MS

Homo sapiens

295

MRPS26

64949

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

296

ATP5O

539

Proximity Label-MS

Homo sapiens

297

MRPS21

Affinity Capture-MS

Homo sapiens

298

ATP5H

10476

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

299

MYCN

Affinity Capture-MS

Homo sapiens

300

NDUFA6

Proximity Label-MS

Homo sapiens

301

DAP3

7818

Affinity Capture-MS		Homo sapiens
Affinity Capture-Western		Homo sapiens
Affinity Capture-Western		Homo sapiens
Co-fractionation		Homo sapiens
Proximity Label-MS		Homo sapiens

302

STOML2

30968

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

303

MRPS30

10884

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

304

MRPL13

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Co-fractionation		Homo sapiens
Proximity Label-MS		Homo sapiens

305

FARS2

10667

Affinity Capture-MS

Homo sapiens

306

MRPL32

64983

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

307

PRDX5

25824

Affinity Capture-MS

Homo sapiens

308

NDUFS4

4724

Proximity Label-MS

Homo sapiens

309

MRPL54

Affinity Capture-MS

Homo sapiens

310

MRPS34

65993

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

311

NSUN4

Affinity Capture-MS

Homo sapiens

312

AGK

55750

Affinity Capture-MS

Homo sapiens

313

ACOT2

10965

Proximity Label-MS

Homo sapiens

314

PTCD3

55037

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

315

HSCB

150274

Proximity Label-MS

Homo sapiens

316

MMAB

326625

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

317

TARS2

80222

Affinity Capture-MS

Homo sapiens

318

DDX54

79039

Proximity Label-MS

Homo sapiens

319

MRPL22

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

320

H2AFY

9555

Proximity Label-MS

Homo sapiens

321

NDUFAF3

25915

Affinity Capture-MS

Homo sapiens

322

MRPS33

Proximity Label-MS

Homo sapiens

323

COX4I1

1327

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

324

OXA1L

Affinity Capture-MS

Homo sapiens

325

PDE12

201626

Proximity Label-MS

Homo sapiens

326

MRPL21

219927

Proximity Label-MS

Homo sapiens

327

MRRF

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

328

NDUFA9

4704

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

329

MRPL35

Proximity Label-MS

Homo sapiens

330

LETM1

3954

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

331

UQCRC2

7385

Affinity Capture-MS

Homo sapiens

332

NFS1

9054

Proximity Label-MS

Homo sapiens

333

RPL3

6122

Co-fractionation

Homo sapiens

334

ELAC2

60528

Proximity Label-MS

Homo sapiens

335

PYCR2

29920

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

336

ECHS1

1892

Proximity Label-MS

Homo sapiens

337

MRPL15

29088

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens
Cross-Linking-MS (XL-MS)		Homo sapiens

338

MRPL1

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

339

CPT2

1376

Affinity Capture-MS

Homo sapiens

340

EIF4H

7458

Co-fractionation

Homo sapiens

341

DKC1

1736

Proximity Label-MS

Homo sapiens

342

YME1L1

10730

Affinity Capture-MS

Homo sapiens

343

PDPR

55066

Proximity Label-MS

Homo sapiens

344

VDAC1

7416

Affinity Capture-MS

Homo sapiens

345

QRSL1

Proximity Label-MS

Homo sapiens

346

MRPL34

Proximity Label-MS

Homo sapiens

347

C10orf2

56652

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

348

AK4

205

Proximity Label-MS

Homo sapiens

349

MRPL42

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Co-fractionation		Homo sapiens
Proximity Label-MS		Homo sapiens

350

GLUD1

2746

Affinity Capture-MS

Homo sapiens

351

SLC25A11

8402

Affinity Capture-MS

Homo sapiens

352

DNAJC19

131118

Proximity Label-MS

Homo sapiens

353

MCAT

27349

Affinity Capture-MS

Homo sapiens

354

MRPS2

51116

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

355

MRPS31

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

356

MRPL43

84545

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

357

DNAJA3

9093

Affinity Capture-MS

Homo sapiens

358

RPS15

6209

Co-fractionation

Homo sapiens

359

NDUFS7

374291

Proximity Label-MS

Homo sapiens

360

PDHB

5162

Proximity Label-MS

Homo sapiens

361

SUCLA2

8803

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

362

C21orf33

Proximity Label-MS

Homo sapiens

363

MTERF4

Affinity Capture-MS

Homo sapiens

364

SFXN1

94081

Affinity Capture-MS

Homo sapiens

365

MOV10

4343

Affinity Capture-MS

Homo sapiens

366

SLC25A4

291

Affinity Capture-MS

Homo sapiens

367

PDK1

5163

Proximity Label-MS

Homo sapiens

368

MRPL46

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

369

RPS8

6202

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

370

GRSF1

2926

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

371

NDUFAF4

29078

Proximity Label-MS

Homo sapiens

372

HNRNPU

3192

Co-fractionation

Homo sapiens

373

METTL17

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

374

MRPS18A

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

375

ECSIT

51295

Proximity Label-MS

Homo sapiens

View the network

Pathways in which ICT1 is involved

Pathway	Evidence	Source
Metabolism of proteins	TAS	Reactome
Metabolism of proteins	IEA	Reactome
Mitochondrial translation	TAS	Reactome
Mitochondrial translation	IEA	Reactome
Mitochondrial translation elongation	TAS	Reactome
Mitochondrial translation elongation	IEA	Reactome
Mitochondrial translation initiation	IEA	Reactome
Mitochondrial translation termination	TAS	Reactome
Translation	TAS	Reactome
Translation	IEA	Reactome

Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here