Gene description for MRPS30
Gene name mitochondrial ribosomal protein S30
Gene symbol MRPS30
Other names/aliases MRP-S30
PAP
PDCD9
S30mt
Species Homo sapiens
 Database cross references - MRPS30
ExoCarta ExoCarta_10884
Vesiclepedia VP_10884
Entrez Gene 10884
HGNC 8769
MIM 611991
UniProt Q9NP92  
 MRPS30 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for MRPS30
Molecular Function
    RNA binding GO:0003723 HDA
    structural constituent of ribosome GO:0003735 IEA
Biological Process
    apoptotic process GO:0006915 TAS
    mitochondrial translation GO:0032543 NAS
Subcellular Localization
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IDA
    mitochondrial inner membrane GO:0005743 NAS
    mitochondrial inner membrane GO:0005743 TAS
    mitochondrial large ribosomal subunit GO:0005762 IBA
    mitochondrial large ribosomal subunit GO:0005762 IDA
    mitochondrial large ribosomal subunit GO:0005762 NAS
 Experiment description of studies that identified MRPS30 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for MRPS30
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 RIT1 6016
Negative Genetic Homo sapiens
3 ZMYND19  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 SLIRP 81892
Proximity Label-MS Homo sapiens
5 H1FNT  
Affinity Capture-MS Homo sapiens
6 MRPL48  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 RBMS3  
Affinity Capture-MS Homo sapiens
8 MRPL30  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 MRPL33  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 RBMS2 5939
Affinity Capture-MS Homo sapiens
11 GTPBP10  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 RPL13A 23521
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 TRUB2  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 MTG2  
Proximity Label-MS Homo sapiens
15 NGRN  
Proximity Label-MS Homo sapiens
16 YBX2 51087
Affinity Capture-MS Homo sapiens
17 RPL10 6134
Affinity Capture-MS Homo sapiens
18 C9orf78 51759
Affinity Capture-MS Homo sapiens
19 MRPL10 124995
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 MRPL27 51264
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
21 MRPL50 54534
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 MRPL52  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 RPUSD4 84881
Proximity Label-MS Homo sapiens
24 MRPL49 740
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 MTRF1  
Proximity Label-MS Homo sapiens
26 GFM2 84340
Proximity Label-MS Homo sapiens
27 MSI1  
Affinity Capture-MS Homo sapiens
28 CCDC90B  
Proximity Label-MS Homo sapiens
29 RPL26L1 51121
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 LRPPRC 10128
Proximity Label-MS Homo sapiens
31 MRPL20 55052
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 PMPCA 23203
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
33 C8orf82  
Proximity Label-MS Homo sapiens
34 Dtl  
Affinity Capture-MS Mus musculus
35 MRPL23 6150
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 YARS2  
Affinity Capture-MS Homo sapiens
37 HINT2 84681
Proximity Label-MS Homo sapiens
38 MRPL12 6182
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 RER1 11079
Affinity Capture-MS Homo sapiens
40 MRPL57  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 MRPS26 64949
Proximity Label-MS Homo sapiens
42 MALSU1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 SRSF3 6428
Affinity Capture-MS Homo sapiens
44 EXD2  
Proximity Label-MS Homo sapiens
45 HIST2H2AC 8338
Affinity Capture-MS Homo sapiens
46 MRPL39 54148
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 GNL3 26354
Affinity Capture-MS Homo sapiens
48 IVD 3712
Affinity Capture-MS Homo sapiens
49 NDUFAB1 4706
Affinity Capture-MS Homo sapiens
50 PMPCB 9512
Proximity Label-MS Homo sapiens
51 MRPL4 51073
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
52 FASTKD2  
Proximity Label-MS Homo sapiens
53 VWA8 23078
Proximity Label-MS Homo sapiens
54 MRPL47 57129
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 RPL19 6143
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
56 SLC25A3 5250
Co-fractionation Homo sapiens
57 CTCF  
Affinity Capture-MS Homo sapiens
58 KIF14 9928
Affinity Capture-MS Homo sapiens
59 RBFOX3  
Affinity Capture-MS Homo sapiens
60 LIN28A  
Affinity Capture-MS Homo sapiens
61 MDH2 4191
Proximity Label-MS Homo sapiens
62 MRPL34  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
63 MRPL13  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
64 RPS9 6203
Affinity Capture-MS Homo sapiens
65 MRPL32 64983
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 C6orf203  
Proximity Label-MS Homo sapiens
67 MRPL17  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
68 FASTKD5  
Proximity Label-MS Homo sapiens
69 MRPL45 84311
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
70 RPL26 6154
Affinity Capture-MS Homo sapiens
71 PARK2  
Affinity Capture-MS Homo sapiens
72 ARMC8 25852
Affinity Capture-MS Homo sapiens
73 MRPL14 64928
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
74 MEX3C 51320
Affinity Capture-MS Homo sapiens
75 TUFM 7284
Proximity Label-MS Homo sapiens
76 MTIF3  
Proximity Label-MS Homo sapiens
77 RPL35 11224
Affinity Capture-MS Homo sapiens
78 PPOX 5498
Affinity Capture-MS Homo sapiens
79 MRPL51 51258
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
80 FGF8  
Affinity Capture-MS Homo sapiens
81 CCDC109B 55013
Proximity Label-MS Homo sapiens
82 HERC2 8924
Affinity Capture-MS Homo sapiens
83 TARS2 80222
Affinity Capture-MS Homo sapiens
84 GFM1 85476
Proximity Label-MS Homo sapiens
85 CYP24A1  
Affinity Capture-MS Homo sapiens
86 KIAA0391  
Affinity Capture-MS Homo sapiens
87 RPL27A 6157
Affinity Capture-MS Homo sapiens
88 HNRNPL 3191
Affinity Capture-MS Homo sapiens
89 MRPL11 65003
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
90 MTRF1L  
Proximity Label-MS Homo sapiens
91 TMEM70  
Proximity Label-MS Homo sapiens
92 CYLD  
Affinity Capture-MS Homo sapiens
93 Katna1  
Affinity Capture-MS Mus musculus
94 MRPL2 51069
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
95 MRPL41 64975
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
96 OXA1L  
Affinity Capture-MS Homo sapiens
97 HNRNPD 3184
Affinity Capture-MS Homo sapiens
98 MRPL44  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
99 MRPL40 64976
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
100 MRPL21 219927
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
101 MRRF  
Proximity Label-MS Homo sapiens
102 MRPS12  
Proximity Label-MS Homo sapiens
103 MRPL46  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
104 MTIF2 4528
Proximity Label-MS Homo sapiens
105 MRPL24  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
106 MRPL35  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
107 YBX1 4904
Affinity Capture-MS Homo sapiens
108 MRPL37 51253
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
109 SRSF4 6429
Affinity Capture-MS Homo sapiens
110 MRPL9 65005
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
111 MRPL16  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
112 RPL37 6167
Affinity Capture-MS Homo sapiens
113 RPS8 6202
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
114 EGFR 1956
Negative Genetic Homo sapiens
115 FAHD1 81889
Affinity Capture-MS Homo sapiens
116 ELAC2 60528
Affinity Capture-MS Homo sapiens
117 GADD45GIP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
118 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
119 FOXL1  
Affinity Capture-MS Homo sapiens
120 C17orf80 55028
Proximity Label-MS Homo sapiens
121 MRPL15 29088
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
122 C12orf65  
Proximity Label-MS Homo sapiens
123 GATB  
Affinity Capture-MS Homo sapiens
124 HSPD1 3329
Affinity Capture-MS Homo sapiens
125 TACO1  
Proximity Label-MS Homo sapiens
126 MTG1  
Proximity Label-MS Homo sapiens
127 RPA3 6119
Proximity Label-MS Homo sapiens
128 THAP3  
Affinity Capture-MS Homo sapiens
129 MRPL3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
130 ACAD9 28976
Proximity Label-MS Homo sapiens
131 RPL23A 6147
Affinity Capture-MS Homo sapiens
132 MRPS17 51373
Affinity Capture-MS Homo sapiens
133 MRPL38  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
134 METTL15  
Proximity Label-MS Homo sapiens
135 SARDH 1757
Affinity Capture-MS Homo sapiens
136 MCUR1 63933
Proximity Label-MS Homo sapiens
137 MRPL18 29074
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
138 RPL13 6137
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
139 CLPP 8192
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
140 CS 1431
Proximity Label-MS Homo sapiens
141 MRPL42  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
142 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
143 TSFM 10102
Proximity Label-MS Homo sapiens
144 AUH 549
Proximity Label-MS Homo sapiens
145 MRPL22  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
146 RPL6 6128
Affinity Capture-MS Homo sapiens
147 ICT1 3396
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
148 LARS2 23395
Affinity Capture-MS Homo sapiens
149 FOXB1  
Affinity Capture-MS Homo sapiens
150 MRPL53  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
151 LSM14A 26065
Affinity Capture-MS Homo sapiens
152 MRPL43 84545
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
153 MRPL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
154 UTP23  
Affinity Capture-MS Homo sapiens
155 MRPL54  
Affinity Capture-MS Homo sapiens
156 C21orf33  
Proximity Label-MS Homo sapiens
157 SSBP1 6742
Proximity Label-MS Homo sapiens
158 TBRG4 9238
Proximity Label-MS Homo sapiens
159 RNMTL1  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
160 VPS26B 112936
Affinity Capture-MS Homo sapiens
161 GLI4  
Affinity Capture-MS Homo sapiens
162 RPUSD3  
Proximity Label-MS Homo sapiens
163 MRPL19 9801
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
164 YKT6 10652
Co-fractionation Homo sapiens
165 GRSF1 2926
Proximity Label-MS Homo sapiens
166 C1QBP 708
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
167 IGF2BP1 10642
Affinity Capture-MS Homo sapiens
168 HNRNPU 3192
Affinity Capture-MS Homo sapiens
169 MRPL55  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
170 RPL36AL 6166
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
171 METTL17  
Proximity Label-MS Homo sapiens
172 MRPL28 10573
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
173 MRPS18A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
174 BCKDHA 593
Affinity Capture-MS Homo sapiens
175 DDX28  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
176 RPL17 6139
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
177 DARS2 55157
Affinity Capture-MS Homo sapiens
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