Gene description for USMG5
Gene name up-regulated during skeletal muscle growth 5 homolog (mouse)
Gene symbol USMG5
Other names/aliases DAPIT
HCVFTP2
bA792D24.4
Species Homo sapiens
 Database cross references - USMG5
ExoCarta ExoCarta_84833
Vesiclepedia VP_84833
Entrez Gene 84833
HGNC 30889
MIM 615204
UniProt Q96IX5  
 USMG5 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for USMG5
Biological Process
    proton motive force-driven ATP synthesis GO:0015986 NAS
Subcellular Localization
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IDA
    mitochondrion GO:0005739 IMP
    mitochondrial inner membrane GO:0005743 NAS
    mitochondrial inner membrane GO:0005743 TAS
    proton-transporting ATP synthase complex GO:0045259 IBA
    proton-transporting ATP synthase complex GO:0045259 IMP
    proton-transporting ATP synthase complex GO:0045259 ISS
 Experiment description of studies that identified USMG5 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for USMG5
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CYB5R1 51706
Co-fractionation Homo sapiens
2 CBX4  
Affinity Capture-MS Homo sapiens
3 REEP5 7905
Affinity Capture-MS Homo sapiens
4 CLPP 8192
Proximity Label-MS Homo sapiens
5 UBE2H 7328
Affinity Capture-MS Homo sapiens
6 VDAC3 7419
Co-fractionation Homo sapiens
7 C15orf48  
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
8 BNIP3 664
Affinity Capture-MS Homo sapiens
9 Heatr2  
Affinity Capture-MS Mus musculus
10 UBQLN4 56893
Two-hybrid Homo sapiens
11 UBL4A 8266
Affinity Capture-MS Homo sapiens
12 SPATS2L 26010
Affinity Capture-MS Homo sapiens
13 HADHA 3030
Co-fractionation Homo sapiens
14 SLC25A3 5250
Co-fractionation Homo sapiens
15 KIF14 9928
Affinity Capture-MS Homo sapiens
16 SFXN1 94081
Co-fractionation Homo sapiens
17 ACOT9 23597
Co-fractionation Homo sapiens
18 PAM16  
Co-fractionation Homo sapiens
19 UNK  
Affinity Capture-RNA Homo sapiens
20 Itgb1 16412
Affinity Capture-MS Mus musculus
21 CYB5R3 1727
Co-fractionation Homo sapiens
22 ATP5A1 498
Affinity Capture-MS Homo sapiens
23 PRDX1 5052
Co-fractionation Homo sapiens
24 VDAC1 7416
Co-fractionation Homo sapiens
25 CUL3 8452
Affinity Capture-MS Homo sapiens
26 COX7A2 1347
Co-fractionation Homo sapiens
27 Timeless  
Affinity Capture-MS Mus musculus
28 LIMK2 3985
Affinity Capture-MS Homo sapiens
29 SAMD1  
Affinity Capture-MS Homo sapiens
30 NDUFA4 4697
Affinity Capture-MS Homo sapiens
31 OTUB1 55611
Affinity Capture-MS Homo sapiens
32 PEX19 5824
Affinity Capture-MS Homo sapiens
33 SOX2  
Affinity Capture-MS Homo sapiens
34 SPRYD4 283377
Affinity Capture-MS Homo sapiens
35 OCIAD1 54940
Affinity Capture-MS Homo sapiens
36 ATP5L 10632
Co-fractionation Homo sapiens
37 BLK 640
Affinity Capture-MS Homo sapiens
38 AURKB 9212
Affinity Capture-MS Homo sapiens
39 KIAA1429 25962
Affinity Capture-MS Homo sapiens
40 ARMC6 93436
Affinity Capture-MS Homo sapiens
41 Crebbp  
Affinity Capture-MS Mus musculus
42 Hsph1 15505
Affinity Capture-MS Mus musculus
43 MGST1 4257
Co-fractionation Homo sapiens
44 SLC25A20 788
Co-fractionation Homo sapiens
45 ATP5D 513
Cross-Linking-MS (XL-MS) Homo sapiens
46 RAPGEF2 9693
Affinity Capture-MS Homo sapiens
47 RPA3 6119
Proximity Label-MS Homo sapiens
48 Kif4  
Affinity Capture-MS Mus musculus
49 Get4  
Affinity Capture-MS Mus musculus
50 COQ9  
Affinity Capture-MS Homo sapiens
51 RAB7A 7879
Co-fractionation Homo sapiens
52 COX7A2L 9167
Co-fractionation Homo sapiens
53 PTPMT1 114971
Affinity Capture-MS Homo sapiens
54 MPHOSPH8 54737
Affinity Capture-MS Homo sapiens
55 CHCHD2  
Affinity Capture-MS Homo sapiens
56 SERBP1 26135
Affinity Capture-MS Homo sapiens
57 DDRGK1 65992
Affinity Capture-MS Homo sapiens
58 UFL1 23376
Affinity Capture-MS Homo sapiens
59 OCIAD2 132299
Co-fractionation Homo sapiens
60 TUBA1C 84790
Affinity Capture-MS Homo sapiens
61 RNF2  
Affinity Capture-MS Homo sapiens
62 C9orf72  
Affinity Capture-MS Homo sapiens
63 ILK 3611
Affinity Capture-MS Homo sapiens
64 CHCHD10  
Affinity Capture-MS Homo sapiens
65 HADHB 3032
Co-fractionation Homo sapiens
66 Ube2i  
Affinity Capture-MS Mus musculus
67 BNIP3L  
Affinity Capture-MS Homo sapiens
68 ARAF 369
Affinity Capture-MS Homo sapiens
69 SEC61B 10952
Co-fractionation Homo sapiens
70 MGST3 4259
Co-fractionation Homo sapiens
71 SCCPDH 51097
Co-fractionation Homo sapiens
72 HUWE1 10075
Affinity Capture-MS Homo sapiens
73 PIGS 94005
Affinity Capture-MS Homo sapiens
74 SLC25A5 292
Co-fractionation Homo sapiens
75 ATP5E 514
Cross-Linking-MS (XL-MS) Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here