Gene description for HDGF
Gene name hepatoma-derived growth factor
Gene symbol HDGF
Other names/aliases HMG1L2
Species Homo sapiens
 Database cross references - HDGF
ExoCarta ExoCarta_3068
Vesiclepedia VP_3068
Entrez Gene 3068
HGNC 4856
MIM 600339
UniProt P51858  
 HDGF identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
 Gene ontology annotations for HDGF
Molecular Function
    nucleotide binding GO:0000166 IEA
    RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IEA
    transcription corepressor binding GO:0001222 IPI
    DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227 IEA
    transcription corepressor activity GO:0003714 IDA
    RNA binding GO:0003723 HDA
    actin binding GO:0003779 IDA
    protein binding GO:0005515 IPI
    growth factor activity GO:0008083 IEA
    heparin binding GO:0008201 IDA
    heparin binding GO:0008201 IDA
    heparin binding GO:0008201 IEA
    tubulin binding GO:0015631 IDA
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 IDA
    chromatin remodeling GO:0006338 IBA
    signal transduction GO:0007165 NAS
    protein localization to nucleus GO:0034504 IEA
    positive regulation of transcription by RNA polymerase II GO:0045944 IEA
    positive regulation of cell division GO:0051781 IDA
    positive regulation of cell division GO:0051781 IDA
Subcellular Localization
    extracellular region GO:0005576 HDA
    extracellular space GO:0005615 HDA
    extracellular space GO:0005615 IDA
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    cytoplasm GO:0005737 IDA
    cytoplasm GO:0005737 IEA
    transcription repressor complex GO:0017053 IDA
    collagen-containing extracellular matrix GO:0062023 HDA
 Experiment description of studies that identified HDGF in sEVs
1
Experiment ID 489
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 207
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 208
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 282
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
13
Experiment ID 283
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
14
Experiment ID 285
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
15
Experiment ID 286
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
16
Experiment ID 407
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
20
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
21
Experiment ID 405
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
24
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
25
Experiment ID 234
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-C3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
26
Experiment ID 236
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
27
Experiment ID 417
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 411
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 418
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 418
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 413
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 211
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
33
Experiment ID 212
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
34
Experiment ID 406
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 415
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
37
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
38
Experiment ID 408
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
39
Experiment ID 409
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
40
Experiment ID 416
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
41
Experiment ID 410
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for HDGF
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
2 HIST1H2BC 8347
Affinity Capture-MS Homo sapiens
3 HIST2H2BE 8349
Affinity Capture-Western Homo sapiens
4 MPG 4350
Affinity Capture-MS Homo sapiens
5 UBE2H 7328
Affinity Capture-MS Homo sapiens
6 SMC3 9126
Affinity Capture-MS Homo sapiens
7 RFC1 5981
Affinity Capture-MS Homo sapiens
8 HIST1H2BE 8344
Affinity Capture-MS Homo sapiens
9 POLDIP3 84271
Affinity Capture-MS Homo sapiens
10 HDAC2 3066
Affinity Capture-MS Homo sapiens
11 RPS11 6205
Affinity Capture-MS Homo sapiens
12 CPOX 1371
Co-fractionation Homo sapiens
13 EIF2S3 1968
Affinity Capture-MS Homo sapiens
14 PGAM5 192111
Affinity Capture-MS Homo sapiens
15 TPD52L2 7165
Co-fractionation Homo sapiens
16 MRTO4 51154
Affinity Capture-MS Homo sapiens
17 MRPS27 23107
Affinity Capture-MS Homo sapiens
18 RCL1 10171
Affinity Capture-MS Homo sapiens
19 HIST1H1D 3007
Affinity Capture-MS Homo sapiens
20 SP1  
Co-fractionation Homo sapiens
21 NACA 4666
Affinity Capture-MS Homo sapiens
22 HIST1H2BG 8339
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 ABCF1 23
Affinity Capture-MS Homo sapiens
24 INTS10  
Affinity Capture-MS Homo sapiens
25 HIST1H4K 8362
Affinity Capture-MS Homo sapiens
26 HIST1H4D 8360
Affinity Capture-MS Homo sapiens
27 TOP1 7150
Affinity Capture-MS Homo sapiens
28 CSNK2A1 1457
Affinity Capture-MS Homo sapiens
29 KPNA2 3838
Affinity Capture-MS Homo sapiens
30 PRSS3 5646
Affinity Capture-MS Homo sapiens
31 SRSF2 6427
Affinity Capture-MS Homo sapiens
32 SNRPF 6636
Co-fractionation Homo sapiens
33 PWP2 5822
Affinity Capture-MS Homo sapiens
34 PRKDC 5591
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
35 APP 351
Reconstituted Complex Homo sapiens
36 RPL22 6146
Affinity Capture-MS Homo sapiens
37 WDR36 134430
Affinity Capture-MS Homo sapiens
38 TMPO 7112
Affinity Capture-MS Homo sapiens
39 APEX1 328
Proximity Label-MS Homo sapiens
40 HP1BP3 50809
Affinity Capture-MS Homo sapiens
41 HIST1H3H 8357
Affinity Capture-MS Homo sapiens
42 EIF4ENIF1 56478
Two-hybrid Homo sapiens
43 HIST1H2BD 3017
Affinity Capture-MS Homo sapiens
44 RUVBL1 8607
Affinity Capture-MS Homo sapiens
45 NCOR1  
Co-fractionation Homo sapiens
46 HIST1H4E 8367
Affinity Capture-MS Homo sapiens
47 EXOSC2 23404
Affinity Capture-MS Homo sapiens
48 RFC3 5983
Affinity Capture-MS Homo sapiens
49 H1FX 8971
Affinity Capture-MS Homo sapiens
50 HIST1H3F 8968
Affinity Capture-MS Homo sapiens
51 HIST1H3G 8355
Affinity Capture-MS Homo sapiens
52 PRMT5 10419
Affinity Capture-MS Homo sapiens
53 DRG1 4733
Affinity Capture-MS Homo sapiens
54 IQGAP1 8826
Co-fractionation Homo sapiens
55 SSB 6741
Affinity Capture-MS Homo sapiens
56 MCTS1 28985
Co-fractionation Homo sapiens
57 FBL 2091
Affinity Capture-MS Homo sapiens
58 H2AFY2 55506
Affinity Capture-MS Homo sapiens
59 SSR1 6745
Affinity Capture-MS Homo sapiens
60 EIF5B 9669
Affinity Capture-MS Homo sapiens
61 HIST1H3A 8350
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
62 HIST4H4 121504
Affinity Capture-MS Homo sapiens
63 POLRMT 5442
Affinity Capture-MS Homo sapiens
64 SLC7A6 9057
Affinity Capture-MS Homo sapiens
65 GRWD1 83743
Affinity Capture-MS Homo sapiens
66 RCC1 1104
Affinity Capture-MS Homo sapiens
67 ITGA8 8516
Cross-Linking-MS (XL-MS) Homo sapiens
68 SRP68 6730
Affinity Capture-MS Homo sapiens
69 U2AF1 7307
Affinity Capture-MS Homo sapiens
70 HIST1H1C 3006
Affinity Capture-MS Homo sapiens
71 EXOSC6 118460
Affinity Capture-MS Homo sapiens
72 MAPK14 1432
Affinity Capture-MS Homo sapiens
73 MYCN  
Affinity Capture-MS Homo sapiens
74 WDR5 11091
Affinity Capture-MS Homo sapiens
75 MSH6 2956
Co-fractionation Homo sapiens
76 YAF2  
Affinity Capture-MS Homo sapiens
77 HIST2H4A 8370
Affinity Capture-MS Homo sapiens
78 SLC25A3 5250
Affinity Capture-MS Homo sapiens
79 PRNP 5621
Affinity Capture-MS Homo sapiens
80 SUB1 10923
Affinity Capture-MS Homo sapiens
81 PSME3 10197
Co-fractionation Homo sapiens
82 RBMX 27316
Affinity Capture-MS Homo sapiens
83 BRIX1 55299
Affinity Capture-MS Homo sapiens
84 HSPA9 3313
Affinity Capture-MS Homo sapiens
85 RAN 5901
Affinity Capture-MS Homo sapiens
86 LRRC59 55379
Affinity Capture-MS Homo sapiens
87 RCC2 55920
Affinity Capture-MS Homo sapiens
88 CPNE2 221184
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
89 FOXC1  
Affinity Capture-MS Homo sapiens
90 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
91 DDX21 9188
Affinity Capture-MS Homo sapiens
92 C7orf26  
Affinity Capture-MS Homo sapiens
93 EMD 2010
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
94 RFC5 5985
Affinity Capture-MS Homo sapiens
95 DIMT1 27292
Affinity Capture-MS Homo sapiens
96 PARK2  
Affinity Capture-MS Homo sapiens
97 WHSC1 7468
Proximity Label-MS Homo sapiens
98 HIST1H3C 8352
Affinity Capture-MS Homo sapiens
99 HIST1H3E 8353
Affinity Capture-MS Homo sapiens
100 SRSF3 6428
Affinity Capture-MS Homo sapiens
101 GTPBP1 9567
Affinity Capture-MS Homo sapiens
102 STAU1 6780
Affinity Capture-MS Homo sapiens
103 TRIM24  
Affinity Capture-MS Homo sapiens
104 NOP2 4839
Affinity Capture-MS Homo sapiens
105 CBX3 11335
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
106 KRT10 3858
Affinity Capture-MS Homo sapiens
107 HIST1H3J 8356
Affinity Capture-MS Homo sapiens
108 DEK 7913
Affinity Capture-MS Homo sapiens
109 SNRPD1 6632
Affinity Capture-MS Homo sapiens
110 JUN 3725
Two-hybrid Homo sapiens
111 NUDC 10726
Affinity Capture-MS Homo sapiens
112 VCP 7415
Affinity Capture-MS Homo sapiens
113 DDX5 1655
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
114 NTRK1 4914
Affinity Capture-MS Homo sapiens
115 ACTL6A 86
Affinity Capture-MS Homo sapiens
116 U2AF2 11338
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
117 HMGA2 8091
Affinity Capture-MS Homo sapiens
118 EEF2 1938
Affinity Capture-MS Homo sapiens
119 DNAJA1 3301
Affinity Capture-MS Homo sapiens
120 NCL 4691
Affinity Capture-MS Homo sapiens
121 FLNB 2317
Cross-Linking-MS (XL-MS) Homo sapiens
122 YWHAQ 10971
Co-fractionation Homo sapiens
123 ENO1 2023
Affinity Capture-RNA Homo sapiens
124 RFC4 5984
Affinity Capture-MS Homo sapiens
125 DDX1 1653
Affinity Capture-MS Homo sapiens
126 KRT2 3849
Affinity Capture-MS Homo sapiens
127 DHX9 1660
Affinity Capture-MS Homo sapiens
128 DDX17 10521
Affinity Capture-MS Homo sapiens
129 HNRNPL 3191
Co-fractionation Homo sapiens
130 HIST1H2BK 85236
Affinity Capture-MS Homo sapiens
131 RRP1B 23076
Affinity Capture-MS Homo sapiens
132 HIST1H2BF 8343
Affinity Capture-MS Homo sapiens
133 MAGEB2 4113
Affinity Capture-MS Homo sapiens
134 HNRNPA3 220988
Affinity Capture-MS Homo sapiens
135 MYBBP1A 10514
Affinity Capture-MS Homo sapiens
136 CEBPA  
Protein-peptide Homo sapiens
137 SRPK1 6732
Affinity Capture-MS Homo sapiens
138 ARID4A  
Co-fractionation Homo sapiens
139 C7orf50 84310
Affinity Capture-MS Homo sapiens
140 HIST1H4C 8364
Affinity Capture-MS Homo sapiens
141 RSL1D1 26156
Affinity Capture-MS Homo sapiens
142 HMGN1  
Affinity Capture-MS Homo sapiens
143 HIST1H4H 8365
Affinity Capture-MS Homo sapiens
144 RPL32 6161
Affinity Capture-MS Homo sapiens
145 OLA1 29789
Co-fractionation Homo sapiens
146 RBM39 9584
Affinity Capture-MS Homo sapiens
147 BMS1  
Affinity Capture-MS Homo sapiens
148 AHCY 191
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
149 AIFM1 9131
Co-fractionation Homo sapiens
150 EXOSC10 5394
Affinity Capture-MS Homo sapiens
151 TRMT10C 54931
Affinity Capture-MS Homo sapiens
152 BAZ1B 9031
Affinity Capture-MS Homo sapiens
153 HIST2H4B 554313
Affinity Capture-MS Homo sapiens
154 LMNB1 4001
Co-fractionation Homo sapiens
155 SMARCA5 8467
Affinity Capture-MS Homo sapiens
156 EIF2S1 1965
Affinity Capture-MS Homo sapiens
157 RPL35 11224
Affinity Capture-MS Homo sapiens
158 CTNNB1 1499
Co-fractionation Homo sapiens
159 SRSF1 6426
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
160 HIST1H1E 3008
Affinity Capture-MS Homo sapiens
161 ASB6 140459
Co-fractionation Homo sapiens
162 UBR7  
Co-fractionation Homo sapiens
163 SRSF5 6430
Affinity Capture-MS Homo sapiens
164 EGFR 1956
Affinity Capture-MS Homo sapiens
165 HSD17B10 3028
Affinity Capture-MS Homo sapiens
166 H1F0 3005
Affinity Capture-MS Homo sapiens
167 DHX30 22907
Affinity Capture-MS Homo sapiens
168 EIF2S2 8894
Affinity Capture-RNA Homo sapiens
Affinity Capture-MS Homo sapiens
169 KRT1 3848
Affinity Capture-MS Homo sapiens
170 RBBP4 5928
Affinity Capture-MS Homo sapiens
171 XBP1  
Two-hybrid Homo sapiens
172 NXF1 10482
Affinity Capture-RNA Homo sapiens
173 EFTUD2 9343
Affinity Capture-MS Homo sapiens
174 HIST1H3B 8358
Affinity Capture-MS Homo sapiens
175 EBNA1BP2 10969
Affinity Capture-MS Homo sapiens
176 FARSB 10056
Affinity Capture-MS Homo sapiens
177 MYC  
Affinity Capture-MS Homo sapiens
178 DDX47 51202
Affinity Capture-MS Homo sapiens
179 PHF6  
Affinity Capture-MS Homo sapiens
180 EXOSC3 51010
Affinity Capture-MS Homo sapiens
181 LYAR 55646
Affinity Capture-MS Homo sapiens
182 RPL10 6134
Affinity Capture-MS Homo sapiens
183 RPL35A 6165
Affinity Capture-MS Homo sapiens
184 KAT5  
Affinity Capture-MS Homo sapiens
185 TBL1X 6907
Co-fractionation Homo sapiens
186 HIST1H4F 8361
Affinity Capture-MS Homo sapiens
187 MAP4 4134
Affinity Capture-MS Homo sapiens
188 RNA18S5  
Affinity Capture-RNA Homo sapiens
189 HIST1H3I 8354
Affinity Capture-MS Homo sapiens
190 CROCC 9696
Co-fractionation Homo sapiens
191 ZC3HAV1 56829
Affinity Capture-MS Homo sapiens
192 HIST1H4I 8294
Affinity Capture-MS Homo sapiens
193 GPR37  
Two-hybrid Homo sapiens
194 HIST1H4B 8366
Affinity Capture-MS Homo sapiens
195 MSN 4478
Co-fractionation Homo sapiens
196 CCND1 595
Co-fractionation Homo sapiens
197 TSR1 55720
Affinity Capture-MS Homo sapiens
198 H2AFY 9555
Affinity Capture-MS Homo sapiens
199 HIST1H2BI 8346
Affinity Capture-MS Homo sapiens
200 SUPT16H 11198
Affinity Capture-MS Homo sapiens
201 GNL3 26354
Affinity Capture-MS Homo sapiens
202 XRCC5 7520
Affinity Capture-MS Homo sapiens
203 RNA28S5  
Affinity Capture-RNA Homo sapiens
204 ASUN  
Affinity Capture-MS Homo sapiens
205 RPL19 6143
Affinity Capture-MS Homo sapiens
206 KRT18 3875
Co-fractionation Homo sapiens
207 DHX15 1665
Affinity Capture-MS Homo sapiens
208 DDX50 79009
Affinity Capture-MS Homo sapiens
209 KIF2A 3796
Affinity Capture-MS Homo sapiens
210 C8orf33 65265
Affinity Capture-MS Homo sapiens
211 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
212 PARP1 142
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
213 KAT2A  
Affinity Capture-MS Homo sapiens
214 MRPS22 56945
Affinity Capture-MS Homo sapiens
215 ZRANB2 9406
Affinity Capture-MS Homo sapiens
216 RPP38 10557
Affinity Capture-MS Homo sapiens
217 THOC3  
Affinity Capture-MS Homo sapiens
218 CKB 1152
Co-fractionation Homo sapiens
219 RPA1 6117
Affinity Capture-MS Homo sapiens
220 HNRNPA2B1 3181
Affinity Capture-MS Homo sapiens
221 HIST1H3D 8351
Affinity Capture-MS Homo sapiens
222 VWA9  
Affinity Capture-MS Homo sapiens
223 PSIP1 11168
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
224 SRP72 6731
Affinity Capture-MS Homo sapiens
225 HDAC1 3065
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
226 CAPZB 832
Affinity Capture-MS Homo sapiens
227 BUB3 9184
Affinity Capture-MS Homo sapiens
228 DDX58 23586
Affinity Capture-RNA Homo sapiens
229 RPS15A 6210
Affinity Capture-MS Homo sapiens
230 CDK1 983
Affinity Capture-MS Homo sapiens
231 RPL34 6164
Affinity Capture-MS Homo sapiens
232 ATAD3A 55210
Affinity Capture-MS Homo sapiens
233 DDX39A 10212
Co-fractionation Homo sapiens
234 TXN 7295
Co-fractionation Homo sapiens
235 HDGFRP2 84717
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
236 HIST1H4L 8368
Affinity Capture-MS Homo sapiens
237 MOV10 4343
Affinity Capture-RNA Homo sapiens
238 ALYREF 10189
Affinity Capture-MS Homo sapiens
239 EGFL6 25975
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
240 RPS23 6228
Affinity Capture-MS Homo sapiens
241 PLS3 5358
Affinity Capture-MS Homo sapiens
242 SRSF7 6432
Affinity Capture-MS Homo sapiens
243 HIST1H4J 8363
Affinity Capture-MS Homo sapiens
244 RPS6 6194
Proximity Label-MS Homo sapiens
245 EIF2AK2 5610
Affinity Capture-MS Homo sapiens
246 XRCC6 2547
Affinity Capture-MS Homo sapiens
247 HNRNPU 3192
Affinity Capture-MS Homo sapiens
248 SH2D4A 63898
Co-fractionation Homo sapiens
249 CKAP4 10970
Affinity Capture-MS Homo sapiens
250 SSRP1 6749
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
251 SLC25A5 292
Affinity Capture-MS Homo sapiens
252 RPL17 6139
Affinity Capture-MS Homo sapiens
253 EP300 2033
Affinity Capture-MS Homo sapiens
254 CDC5L 988
Affinity Capture-MS Homo sapiens
255 UBA52 7311
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here