Gene description for NOP2
Gene name NOP2 nucleolar protein
Gene symbol NOP2
Other names/aliases NOL1
NOP120
NSUN1
p120
Species Homo sapiens
 Database cross references - NOP2
ExoCarta ExoCarta_4839
Vesiclepedia VP_4839
Entrez Gene 4839
HGNC 7867
MIM 164031
UniProt P46087  
 NOP2 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 36706192    
Embryonic kidney cells 36706192    
Hepatocellular carcinoma cells 26054723    
Mesenchymal stem cells 36408942    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Squamous carcinoma cells 20124223    
Thymus 23844026    
 Gene ontology annotations for NOP2
Molecular Function
    RNA binding GO:0003723 HDA
    protein binding GO:0005515 IPI
    rRNA (cytosine-C5-)-methyltransferase activity GO:0009383 IBA
    rRNA (cytosine-C5-)-methyltransferase activity GO:0009383 IDA
    rRNA (cytosine-C5-)-methyltransferase activity GO:0009383 IMP
Biological Process
    ribosomal large subunit assembly GO:0000027 IMP
    maturation of LSU-rRNA GO:0000470 IBA
    rRNA processing GO:0006364 IDA
    positive regulation of cell population proliferation GO:0008284 IDA
    ribosomal large subunit biogenesis GO:0042273 IDA
    rRNA base methylation GO:0070475 IBA
    regulation of signal transduction by p53 class mediator GO:1901796 IMP
Subcellular Localization
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 TAS
    nucleolus GO:0005730 HDA
    nucleolus GO:0005730 IBA
    nucleolus GO:0005730 IDA
 Experiment description of studies that identified NOP2 in sEVs
1
Experiment ID 489
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
6
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 498
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 207
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 208
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 1203
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
13
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 1275
MISEV standards
Biophysical techniques
✔ Enriched markers
✔ Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 1280
MISEV standards
Biophysical techniques
✔ Enriched markers
✔ Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T - Fraction 5
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density 1.151 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 236
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
20
Experiment ID 488
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
21
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
23
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
24
Experiment ID 217
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for NOP2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CD3EAP  
Proximity Label-MS Homo sapiens
2 MCRS1  
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
3 ZNF668  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 UBE2H 7328
Affinity Capture-MS Homo sapiens
5 RPL26L1 51121
Affinity Capture-MS Homo sapiens
6 Sgol2  
Affinity Capture-MS Mus musculus
7 RSL1D1 26156
Co-fractionation Homo sapiens
8 CDCA7L  
Two-hybrid Homo sapiens
9 NOP58 51602
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
10 LGR4 55366
Affinity Capture-MS Homo sapiens
11 HIST1H2BH 8345
Cross-Linking-MS (XL-MS) Homo sapiens
12 RPL15 6138
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
13 PAXIP1  
Affinity Capture-MS Homo sapiens
14 RPS3A 6189
Affinity Capture-MS Homo sapiens
15 ZNF320  
Affinity Capture-MS Homo sapiens
16 RNF4 6047
Affinity Capture-MS Homo sapiens
17 RPL30 6156
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
18 PKM 5315
Cross-Linking-MS (XL-MS) Homo sapiens
19 SRPK2 6733
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
20 LMNB1 4001
Affinity Capture-MS Homo sapiens
21 TARDBP 23435
Affinity Capture-MS Homo sapiens
22 LHX2  
Proximity Label-MS Homo sapiens
23 RPL37A 6168
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 Ybx1 22608
Affinity Capture-MS Mus musculus
25 ACTC1 70
Proximity Label-MS Homo sapiens
26 NOP56 10528
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
27 DHX8 1659
Affinity Capture-MS Homo sapiens
28 IMP4  
Affinity Capture-MS Homo sapiens
29 RPL10 6134
Affinity Capture-MS Homo sapiens
30 KIF20A 10112
Affinity Capture-MS Homo sapiens
31 PPAN-P2RY11  
Affinity Capture-MS Homo sapiens
32 MAP4K4 9448
Co-fractionation Homo sapiens
33 PRPF8 10594
Co-fractionation Homo sapiens
34 CAND1 55832
Affinity Capture-MS Homo sapiens
35 RSBN1  
Affinity Capture-MS Homo sapiens
36 ZNF92  
Affinity Capture-MS Homo sapiens
37 DDX47 51202
Co-fractionation Homo sapiens
38 Ktn1  
Affinity Capture-MS Mus musculus
39 SPTY2D1  
Affinity Capture-MS Homo sapiens
40 SOX2  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 WDR36 134430
Affinity Capture-MS Homo sapiens
42 CENPA  
Proximity Label-MS Homo sapiens
43 ILF2 3608
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 APEX1 328
Affinity Capture-RNA Homo sapiens
Proximity Label-MS Homo sapiens
45 EGFR 1956
Negative Genetic Homo sapiens
46 RPL32 6161
Affinity Capture-MS Homo sapiens
47 DDX23 9416
Proximity Label-MS Homo sapiens
48 GPATCH4 54865
Affinity Capture-MS Homo sapiens
49 RPL10A 4736
Affinity Capture-MS Homo sapiens
50 HIST1H1A 3024
Affinity Capture-MS Homo sapiens
51 ZNF189  
Affinity Capture-MS Homo sapiens
52 PRR11  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 RPL7A 6130
Affinity Capture-MS Homo sapiens
54 RPL28 6158
Affinity Capture-MS Homo sapiens
55 CEP70  
Two-hybrid Homo sapiens
56 KIF23 9493
Affinity Capture-MS Homo sapiens
57 DDX24 57062
Co-fractionation Homo sapiens
58 MPHOSPH8 54737
Affinity Capture-MS Homo sapiens
59 CCDC137  
Affinity Capture-MS Homo sapiens
60 NUFIP1  
Affinity Capture-MS Homo sapiens
61 MPHOSPH10 10199
Co-fractionation Homo sapiens
62 COPS5 10987
Affinity Capture-MS Homo sapiens
63 SIRT6  
Affinity Capture-MS Homo sapiens
64 PRC1 9055
Affinity Capture-MS Homo sapiens
65 NPM1 4869
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 RAB2B 84932
Two-hybrid Homo sapiens
67 ETV4  
Affinity Capture-MS Homo sapiens
68 FBL 2091
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
69 H2AFY2 55506
Affinity Capture-MS Homo sapiens
70 OBSL1 23363
Affinity Capture-MS Homo sapiens
71 RPS5 6193
Co-fractionation Homo sapiens
72 URB1 9875
Affinity Capture-MS Homo sapiens
73 MYCN  
Affinity Capture-MS Homo sapiens
74 RPLP2 6181
Affinity Capture-MS Homo sapiens
75 ADARB1 104
Affinity Capture-MS Homo sapiens
76 TTF1  
Affinity Capture-MS Homo sapiens
77 PRKRA 8575
Affinity Capture-MS Homo sapiens
78 DDX51  
Affinity Capture-MS Homo sapiens
79 NIFK 84365
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
80 EED  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
81 SRP68 6730
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
82 KLF4  
Affinity Capture-MS Homo sapiens
83 DDX18 8886
Co-fractionation Homo sapiens
84 ATG16L1 55054
Affinity Capture-MS Homo sapiens
85 NOC3L 64318
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
86 ZNF346  
Affinity Capture-MS Homo sapiens
87 MECP2 4204
Affinity Capture-MS Homo sapiens
88 GLTSCR2  
Affinity Capture-MS Homo sapiens
89 CUL1 8454
Affinity Capture-MS Homo sapiens
90 ARIH2 10425
Affinity Capture-MS Homo sapiens
91 MAK16  
Affinity Capture-MS Homo sapiens
92 NCSTN 23385
Co-fractionation Homo sapiens
93 RPL19 6143
Co-fractionation Homo sapiens
94 RBM8A 9939
Affinity Capture-MS Homo sapiens
95 KIF14 9928
Affinity Capture-MS Homo sapiens
96 ESR1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
97 PES1 23481
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
98 LIN28A  
Affinity Capture-MS Homo sapiens
99 BRIX1 55299
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
100 ASH1L 55870
Affinity Capture-MS Homo sapiens
101 CHMP4C 92421
Affinity Capture-MS Homo sapiens
102 EIF2AK2 5610
Affinity Capture-MS Homo sapiens
103 DDX31  
Affinity Capture-MS Homo sapiens
104 NOLC1 9221
Co-fractionation Homo sapiens
105 KIAA0020 9933
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
106 UTP14A 10813
Co-fractionation Homo sapiens
107 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
108 DDX21 9188
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
109 ZNF7  
Affinity Capture-MS Homo sapiens
110 RPL4 6124
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
111 RBM28 55131
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
112 NOL6 65083
Co-fractionation Homo sapiens
113 CENPV 201161
Affinity Capture-MS Homo sapiens
114 SRSF3 6428
Co-fractionation Homo sapiens
115 KPNA6 23633
Two-hybrid Homo sapiens
116 DNAJC2 27000
Affinity Capture-MS Homo sapiens
117 STAU1 6780
Affinity Capture-MS Homo sapiens
118 RPL5 6125
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
119 BAG6 7917
Affinity Capture-MS Homo sapiens
120 SRSF6 6431
Affinity Capture-MS Homo sapiens
121 PURG  
Affinity Capture-MS Homo sapiens
122 GTPBP10  
Affinity Capture-MS Homo sapiens
123 Ctcf 13018
Affinity Capture-MS Mus musculus
124 ZNF22  
Affinity Capture-MS Homo sapiens
125 UBE2I 7329
Biochemical Activity Homo sapiens
126 UTP15 84135
Affinity Capture-MS Homo sapiens
127 RPL18A 6142
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
128 TOP3B 8940
Affinity Capture-MS Homo sapiens
129 NOC2L 26155
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
130 NFIA 4774
Co-fractionation Homo sapiens
131 CHMP4B 128866
Affinity Capture-MS Homo sapiens
132 ZNF430  
Affinity Capture-MS Homo sapiens
133 NTRK1 4914
Affinity Capture-MS Homo sapiens
134 RPL31 6160
Proximity Label-MS Homo sapiens
135 RPS7 6201
Co-fractionation Homo sapiens
136 IFI16 3428
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
137 Mki67 17345
Affinity Capture-MS Mus musculus
138 REXO4  
Affinity Capture-MS Homo sapiens
139 SYNCRIP 10492
Affinity Capture-MS Homo sapiens
140 SUMO2 6613
Reconstituted Complex Homo sapiens
141 Srp72  
Affinity Capture-MS Mus musculus
142 RPL36 25873
Affinity Capture-MS Homo sapiens
143 HIST1H1C 3006
Cross-Linking-MS (XL-MS) Homo sapiens
144 DDX54 79039
Affinity Capture-MS Homo sapiens
145 EZH2  
Affinity Capture-MS Homo sapiens
146 DHX40  
Proximity Label-MS Homo sapiens
147 HECTD1 25831
Affinity Capture-MS Homo sapiens
148 CDK12 51755
Affinity Capture-MS Homo sapiens
149 RPLP0 6175
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
150 ZNF107  
Affinity Capture-MS Homo sapiens
151 SRPK3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
152 MAGEB2 4113
Affinity Capture-MS Homo sapiens
153 RPS26P11  
Affinity Capture-MS Homo sapiens
154 HDAC5 10014
Affinity Capture-MS Homo sapiens
155 DDX27 55661
Affinity Capture-MS Homo sapiens
156 Ksr1  
Affinity Capture-MS Mus musculus
157 GTPBP4 23560
Co-fractionation Homo sapiens
158 CYLD  
Affinity Capture-MS Homo sapiens
159 SRPK1 6732
Co-fractionation Homo sapiens
160 PITX2  
Affinity Capture-MS Homo sapiens
161 BRCA1 672
Affinity Capture-MS Homo sapiens
162 CPNE4 131034
Affinity Capture-MS Homo sapiens
163 RPL11 6135
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
164 WDR46  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
165 CNBP 7555
Affinity Capture-MS Homo sapiens
166 ANLN 54443
Affinity Capture-MS Homo sapiens
167 RRP8  
Affinity Capture-MS Homo sapiens
168 TLX2  
Proximity Label-MS Homo sapiens
169 RPL23A 6147
Co-fractionation Homo sapiens
170 LOC255308 255308
Co-fractionation Homo sapiens
171 BRF1  
Affinity Capture-MS Homo sapiens
172 ZBTB2 57621
Affinity Capture-MS Homo sapiens
173 BMS1  
Affinity Capture-MS Homo sapiens
174 RPF2 84154
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
175 ZNF770 54989
Affinity Capture-MS Homo sapiens
176 HIST1H3A 8350
Cross-Linking-MS (XL-MS) Homo sapiens
177 FANCD2  
Affinity Capture-MS Homo sapiens
178 NKX2-5  
Affinity Capture-MS Homo sapiens
179 METTL14  
Affinity Capture-MS Homo sapiens
180 RPL23 9349
Co-fractionation Homo sapiens
181 MRTO4 51154
Co-fractionation Homo sapiens
182 RPS2 6187
Co-fractionation Homo sapiens
183 OTUD1 220213
Affinity Capture-MS Homo sapiens
184 CHCHD1  
Proximity Label-MS Homo sapiens
185 EIF6 3692
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
186 RC3H2  
Affinity Capture-MS Homo sapiens
187 ECT2 1894
Affinity Capture-MS Homo sapiens
188 SIRT7  
Affinity Capture-MS Homo sapiens
189 NAT10 55226
Co-fractionation Homo sapiens
190 MEX3A  
Affinity Capture-RNA Homo sapiens
191 HIST1H1E 3008
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
192 NPM3 10360
Affinity Capture-MS Homo sapiens
193 ZNF791  
Affinity Capture-MS Homo sapiens
194 RPL14 9045
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
195 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
196 RPS6 6194
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
197 SRSF5 6430
Affinity Capture-MS Homo sapiens
198 RPL3 6122
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
199 EBNA1BP2 10969
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
200 URB2  
Affinity Capture-MS Homo sapiens
201 BBX 56987
Affinity Capture-MS Homo sapiens
202 RPL7 6129
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
203 SUZ12  
Affinity Capture-MS Homo sapiens
204 NIP7 51388
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
205 ZNF624 57547
Affinity Capture-MS Homo sapiens
206 SOX15  
Affinity Capture-MS Homo sapiens
207 AURKB 9212
Affinity Capture-MS Homo sapiens
208 ZNF512  
Affinity Capture-MS Homo sapiens
209 C12orf65  
Proximity Label-MS Homo sapiens
210 CDK2 1017
Co-fractionation Homo sapiens
211 CEP250 11190
Affinity Capture-MS Homo sapiens
212 BUD13  
Affinity Capture-MS Homo sapiens
213 GLYR1 84656
Affinity Capture-MS Homo sapiens
214 FBXL6  
Affinity Capture-MS Homo sapiens
215 MYC  
Affinity Capture-MS Homo sapiens
216 RPA3 6119
Proximity Label-MS Homo sapiens
217 CEBPZ  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
218 MAGEB10  
Affinity Capture-MS Homo sapiens
219 ZCCHC6 79670
Affinity Capture-MS Homo sapiens
220 DNAJC9 23234
Proximity Label-MS Homo sapiens
221 NOL12 79159
Affinity Capture-MS Homo sapiens
222 CSNK2A2 1459
Co-fractionation Homo sapiens
223 TOP1 7150
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
224 TAF1A  
Affinity Capture-MS Homo sapiens
225 DKC1 1736
Co-fractionation Homo sapiens
226 HP1BP3 50809
Co-fractionation Homo sapiens
227 SART3 9733
Affinity Capture-MS Homo sapiens
228 SKIV2L2 23517
Co-fractionation Homo sapiens
229 ZNF724P  
Affinity Capture-MS Homo sapiens
230 DNAJC1 64215
Affinity Capture-MS Homo sapiens
231 RPL18 6141
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
232 DDRGK1 65992
Affinity Capture-MS Homo sapiens
233 RNF2  
Affinity Capture-MS Homo sapiens
234 ZC3HAV1 56829
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
235 PML 5371
Affinity Capture-MS Homo sapiens
236 PDCD11 22984
Affinity Capture-MS Homo sapiens
237 RPS15A 6210
Co-fractionation Homo sapiens
238 Eif3e 16341
Affinity Capture-MS Mus musculus
239 RPL26 6154
Affinity Capture-MS Homo sapiens
240 ZC3H3  
Affinity Capture-MS Homo sapiens
241 DDX52  
Affinity Capture-MS Homo sapiens
242 FTSJ3 117246
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
243 GNL3 26354
Co-fractionation Homo sapiens
244 CCDC8  
Affinity Capture-MS Homo sapiens
245 RPS16 6217
Affinity Capture-MS Homo sapiens
246 RPL13 6137
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
247 YTHDC2 64848
Affinity Capture-MS Homo sapiens
248 SURF6  
Affinity Capture-MS Homo sapiens
249 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
250 RC3H1 149041
Affinity Capture-MS Homo sapiens
251 DNAJB6 10049
Proximity Label-MS Homo sapiens
252 PARP1 142
Proximity Label-MS Homo sapiens
253 HDGF 3068
Affinity Capture-MS Homo sapiens
254 HIST1H2BK 85236
Cross-Linking-MS (XL-MS) Homo sapiens
255 RRS1 23212
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
256 TP53 7157
Affinity Capture-MS Homo sapiens
257 RPL6 6128
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
258 VPS52 6293
Two-hybrid Homo sapiens
259 MNDA 4332
Affinity Capture-MS Homo sapiens
260 RPLP0P6 220717
Co-fractionation Homo sapiens
261 MCM5 4174
Affinity Capture-MS Homo sapiens
262 USP36  
Affinity Capture-MS Homo sapiens
263 RPS8 6202
Co-fractionation Homo sapiens
264 MEN1 4221
Affinity Capture-MS Homo sapiens
265 BOP1 23246
Co-fractionation Homo sapiens
266 DGCR8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
267 KNOP1 400506
Affinity Capture-MS Homo sapiens
268 RPS4X 6191
Co-fractionation Homo sapiens
269 ZNF48  
Affinity Capture-MS Homo sapiens
270 NHLRC2 374354
Affinity Capture-MS Homo sapiens
271 UTP23  
Affinity Capture-MS Homo sapiens
272 NSA2  
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
273 NOL8  
Affinity Capture-MS Homo sapiens
274 TAF1D  
Affinity Capture-MS Homo sapiens
275 DDX58 23586
Affinity Capture-RNA Homo sapiens
276 RPF1  
Affinity Capture-MS Homo sapiens
277 MYBBP1A 10514
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
278 TOP2A 7153
Co-fractionation Homo sapiens
279 THAP7  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
280 UFL1 23376
Affinity Capture-MS Homo sapiens
281 ZNF317 57693
Affinity Capture-MS Homo sapiens
282 KRR1 11103
Co-fractionation Homo sapiens
283 RBM4 5936
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
284 CEBPA  
Protein-peptide Homo sapiens
285 ZNF746  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
286 RPS24 6229
Proximity Label-MS Homo sapiens
287 MOV10 4343
Affinity Capture-RNA Homo sapiens
288 ALYREF 10189
Co-fractionation Homo sapiens
289 MT1F  
Two-hybrid Homo sapiens
290 PARK2  
Affinity Capture-MS Homo sapiens
291 MINK1 50488
Co-fractionation Homo sapiens
292 TRAP1 10131
Affinity Capture-MS Homo sapiens
293 SORT1 6272
Affinity Capture-MS Homo sapiens
294 PINK1  
Affinity Capture-MS Homo sapiens
295 Rrbp1  
Affinity Capture-MS Mus musculus
296 RPL8 6132
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
297 TAF1C  
Affinity Capture-MS Homo sapiens
298 GRSF1 2926
Proximity Label-MS Homo sapiens
299 ELF3 1999
Affinity Capture-MS Homo sapiens
300 LDLR 3949
Positive Genetic Homo sapiens
301 ZNF445  
Affinity Capture-MS Homo sapiens
302 CUL7 9820
Affinity Capture-MS Homo sapiens
303 KRAS 3845
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
304 HNRNPU 3192
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
305 C9orf72  
Affinity Capture-MS Homo sapiens
306 RPL36AL 6166
Affinity Capture-MS Homo sapiens
307 RBM34  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
308 ZNF431  
Affinity Capture-MS Homo sapiens
309 SSRP1 6749
Co-fractionation Homo sapiens
310 PRMT1 3276
Affinity Capture-MS Homo sapiens
311 ZNF467  
Affinity Capture-MS Homo sapiens
312 NVL  
Affinity Capture-MS Homo sapiens
313 DDX56  
Co-fractionation Homo sapiens
314 H1FOO 132243
Affinity Capture-MS Homo sapiens
315 RPL17 6139
Affinity Capture-MS Homo sapiens
316 EP300 2033
Affinity Capture-MS Homo sapiens
317 CDC5L 988
Co-fractionation Homo sapiens
318 NHLH1  
Proximity Label-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here