Gene description for PABPC4
Gene name poly(A) binding protein, cytoplasmic 4 (inducible form)
Gene symbol PABPC4
Other names/aliases APP-1
APP1
PABP4
iPABP
Species Homo sapiens
 Database cross references - PABPC4
ExoCarta ExoCarta_8761
Vesiclepedia VP_8761
Entrez Gene 8761
HGNC 8557
MIM 603407
UniProt Q13310  
 PABPC4 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 35918900    
Breast cancer cells 35918900    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Prostate cancer cells 25844599    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Serum 25844599    
Serum 25844599    
Serum 25844599    
Serum 25844599    
Serum 25844599    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
 Gene ontology annotations for PABPC4
Molecular Function
    RNA binding GO:0003723 HDA
    mRNA 3'-UTR binding GO:0003730 IBA
    protein binding GO:0005515 IPI
    poly(A) binding GO:0008143 IBA
    poly(A) binding GO:0008143 IDA
    poly(U) RNA binding GO:0008266 IBA
    poly(U) RNA binding GO:0008266 IDA
    poly(C) RNA binding GO:0017130 IDA
Biological Process
    RNA processing GO:0006396 TAS
    RNA catabolic process GO:0006401 TAS
    translation GO:0006412 TAS
    blood coagulation GO:0007596 TAS
    regulation of mRNA stability GO:0043488 IEA
    myeloid cell development GO:0061515 IEA
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    cytoplasm GO:0005737 IDA
    cytosol GO:0005829 IBA
    cytosol GO:0005829 IDA
    cytoplasmic stress granule GO:0010494 IBA
    cytoplasmic stress granule GO:0010494 IDA
    ribonucleoprotein complex GO:1990904 IBA
    ribonucleoprotein complex GO:1990904 IDA
 Experiment description of studies that identified PABPC4 in sEVs
1
Experiment ID 489
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 1333
MISEV standards
Biophysical techniques
✔ Enriched markers
✘ Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
Western blotting
10
Experiment ID 1333
MISEV standards
Biophysical techniques
✔ Enriched markers
✘ Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
Western blotting
11
Experiment ID 1335
MISEV standards
Biophysical techniques
✔ Enriched markers
✘ Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
12
Experiment ID 1335
MISEV standards
Biophysical techniques
✔ Enriched markers
✘ Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
13
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
14
Experiment ID 498
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
15
Experiment ID 207
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 208
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
18
Experiment ID 407
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
22
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
23
Experiment ID 405
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
25
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
26
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
27
Experiment ID 235
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
28
Experiment ID 236
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
29
Experiment ID 417
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 411
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 488
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
32
Experiment ID 418
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
33
Experiment ID 224
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
34
Experiment ID 413
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 211
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
36
Experiment ID 212
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
37
Experiment ID 406
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
38
Experiment ID 415
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
39
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
40
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
41
Experiment ID 408
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
42
Experiment ID 409
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
43
Experiment ID 416
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
44
Experiment ID 274
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
45
Experiment ID 834
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
46
Experiment ID 835
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
47
Experiment ID 276
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Serum
Sample name Serum - Docetaxel resistant castration resistant prostate cancer patient 1
Isolation/purification methods Filtration
Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
48
Experiment ID 278
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Serum
Sample name Serum - Docetaxel resistant castration resistant prostate cancer patient 3
Isolation/purification methods Filtration
Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
49
Experiment ID 279
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Serum
Sample name Serum - Docetaxel sensitive castration resistant prostate cancer patient 4
Isolation/purification methods Filtration
Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
50
Experiment ID 280
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Serum
Sample name Serum - Docetaxel sensitive castration resistant prostate cancer patient 5
Isolation/purification methods Filtration
Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
51
Experiment ID 281
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Serum
Sample name Serum - Docetaxel sensitive castration resistant prostate cancer patient 6
Isolation/purification methods Filtration
Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
52
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
53
Experiment ID 410
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for PABPC4
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 EIF4G3 8672
Co-fractionation Homo sapiens
2 HNRNPH1 3187
Co-fractionation Homo sapiens
3 SLIRP 81892
Affinity Capture-MS Homo sapiens
4 MSI2 124540
Co-fractionation Homo sapiens
5 PABPC1 26986
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 TRIM3 10612
Affinity Capture-MS Homo sapiens
7 UBL4A 8266
Affinity Capture-MS Homo sapiens
8 QARS 5859
Co-fractionation Homo sapiens
9 BAG3 9531
Affinity Capture-MS Homo sapiens
10 RPL15 6138
Co-fractionation Homo sapiens
11 HSPA6 3310
Co-fractionation Homo sapiens
12 ANLN 54443
Affinity Capture-MS Homo sapiens
13 EIF2S3 1968
Affinity Capture-MS Homo sapiens
14 RIN3  
Affinity Capture-MS Homo sapiens
15 SRPK2 6733
FRET Homo sapiens
Affinity Capture-MS Homo sapiens
16 TARDBP 23435
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
17 SAP30L  
Affinity Capture-MS Homo sapiens
18 RPA2 6118
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
19 RPL13A 23521
Co-fractionation Homo sapiens
20 Ybx1 22608
Affinity Capture-MS Mus musculus
21 LIN28A  
Affinity Capture-MS Homo sapiens
22 TSG101 7251
Affinity Capture-MS Homo sapiens
23 KIF20A 10112
Affinity Capture-MS Homo sapiens
24 UBC 7316
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
25 CSNK2A1 1457
Affinity Capture-MS Homo sapiens
26 RPL18A 6142
Co-fractionation Homo sapiens
27 CAND1 55832
Affinity Capture-MS Homo sapiens
28 HNRNPR 10236
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
29 SRP72 6731
Affinity Capture-MS Homo sapiens
30 RNF208  
Affinity Capture-MS Homo sapiens
31 TMPO 7112
Affinity Capture-MS Homo sapiens
32 ILF2 3608
Affinity Capture-MS Homo sapiens
33 GSK3A 2931
Affinity Capture-MS Homo sapiens
34 PPP1CC 5501
Affinity Capture-MS Homo sapiens
35 SURF2  
Affinity Capture-MS Homo sapiens
36 TNRC6C  
Affinity Capture-MS Homo sapiens
37 PARK2  
Affinity Capture-MS Homo sapiens
38 RPS20 6224
Proximity Label-MS Homo sapiens
39 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
40 GSPT2 23708
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 TRIM28 10155
Affinity Capture-MS Homo sapiens
42 PRR11  
Affinity Capture-MS Homo sapiens
43 EDC4 23644
Affinity Capture-MS Homo sapiens
44 PRDX3 10935
Co-fractionation Homo sapiens
45 KIF23 9493
Affinity Capture-MS Homo sapiens
46 MCM2 4171
Affinity Capture-MS Homo sapiens
47 ATXN2L 11273
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
48 EIF3B 8662
Affinity Capture-MS Homo sapiens
49 COPS5 10987
Affinity Capture-MS Homo sapiens
50 METAP2 10988
Affinity Capture-MS Homo sapiens
51 PRC1 9055
Affinity Capture-MS Homo sapiens
52 NPM1 4869
Affinity Capture-MS Homo sapiens
53 FBL 2091
Co-fractionation Homo sapiens
54 YWHAG 7532
Co-fractionation Homo sapiens
55 IFIT3 3437
Affinity Capture-MS Homo sapiens
56 APRT 353
Co-fractionation Homo sapiens
57 RPS9 6203
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
58 MYCN  
Affinity Capture-MS Homo sapiens
59 GSPT1 2935
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
60 ITGA4 3676
Affinity Capture-MS Homo sapiens
61 CDC27 996
Protein-RNA Homo sapiens
Affinity Capture-RNA Homo sapiens
62 SRP68 6730
Affinity Capture-MS Homo sapiens
63 KLF4  
Affinity Capture-MS Homo sapiens
64 YWHAB 7529
Affinity Capture-MS Homo sapiens
65 DDX6 1656
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 RC3H2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
67 Gspt1 14852
Affinity Capture-MS Mus musculus
68 CUL1 8454
Affinity Capture-MS Homo sapiens
69 PSPC1 55269
Affinity Capture-MS Homo sapiens
70 MAPRE1 22919
Affinity Capture-MS Homo sapiens
71 RPS11 6205
Affinity Capture-MS Homo sapiens
72 SREK1 140890
Affinity Capture-MS Homo sapiens
73 SOD1 6647
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
74 EEF1A1 1915
Co-fractionation Homo sapiens
75 CTCF  
Affinity Capture-MS Homo sapiens
76 KIF14 9928
Affinity Capture-MS Homo sapiens
77 LARP4B 23185
Affinity Capture-MS Homo sapiens
78 HSPA8 3312
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
79 WDR1 9948
Co-fractionation Homo sapiens
80 ATXN2 6311
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
81 CPEB1  
Affinity Capture-MS Homo sapiens
82 BRIX1 55299
Co-fractionation Homo sapiens
83 HSPA9 3313
Co-fractionation Homo sapiens
84 PPM1B 5495
Affinity Capture-MS Homo sapiens
85 NF2 4771
Affinity Capture-MS Homo sapiens
86 EIF2AK2 5610
Affinity Capture-MS Homo sapiens
87 SF3A2 8175
Co-fractionation Homo sapiens
88 COX15 1355
Affinity Capture-MS Homo sapiens
89 USP10 9100
Affinity Capture-MS Homo sapiens
90 CRY1  
Affinity Capture-MS Homo sapiens
91 DCP1B  
Affinity Capture-MS Homo sapiens
92 PCF11 51585
Co-fractionation Homo sapiens
93 PINX1  
Affinity Capture-MS Homo sapiens
94 CUL4B 8450
Affinity Capture-MS Homo sapiens
95 RPL4 6124
Affinity Capture-MS Homo sapiens
96 DRG1 4733
Affinity Capture-MS Homo sapiens
97 HIST1H1B 3009
Affinity Capture-MS Homo sapiens
98 PAN2  
Affinity Capture-MS Homo sapiens
99 TRA2A 29896
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
100 XRN1 54464
Two-hybrid Homo sapiens
101 GLE1 2733
Affinity Capture-MS Homo sapiens
102 STAU1 6780
Affinity Capture-MS Homo sapiens
103 PURG  
Affinity Capture-MS Homo sapiens
104 BZLF1  
Affinity Capture-MS
105 TRIM37  
Protein-RNA Homo sapiens
Affinity Capture-RNA Homo sapiens
106 Pabpc1 18458
Affinity Capture-MS Mus musculus
107 RPL5 6125
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
108 SKI 6497
Affinity Capture-MS Homo sapiens
109 RB1CC1 9821
Affinity Capture-MS Homo sapiens
110 MKRN2 23609
Affinity Capture-MS Homo sapiens
111 YWHAE 7531
Affinity Capture-MS Homo sapiens
112 DDX5 1655
Co-fractionation Homo sapiens
113 NTRK1 4914
Affinity Capture-MS Homo sapiens
114 RNPEP 6051
Co-fractionation Homo sapiens
115 IFI16 3428
Affinity Capture-MS Homo sapiens
116 U2AF2 11338
Affinity Capture-MS Homo sapiens
117 DCP1A 55802
Affinity Capture-MS Homo sapiens
118 SYNCRIP 10492
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
119 NCL 4691
Co-fractionation Homo sapiens
120 LUC7L2 51631
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
121 OAS3 4940
Affinity Capture-MS Homo sapiens
122 YWHAQ 10971
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
123 ALYREF 10189
Co-fractionation Homo sapiens
124 Nhp2l1 20826
Affinity Capture-MS Mus musculus
125 HECTD1 25831
Affinity Capture-MS Homo sapiens
126 ENY2 56943
Affinity Capture-MS Homo sapiens
127 CUL2 8453
Affinity Capture-MS Homo sapiens
128 RPS16 6217
Affinity Capture-MS Homo sapiens
129 DDX39B 7919
Co-fractionation Homo sapiens
130 CEBPA  
Protein-peptide Homo sapiens
131 CYLD  
Affinity Capture-MS Homo sapiens
132 NFX1  
Affinity Capture-MS Homo sapiens
133 OGT 8473
Reconstituted Complex Homo sapiens
134 IGBP1 3476
Co-fractionation Homo sapiens
135 RPLP0 6175
Co-fractionation Homo sapiens
136 CNBP 7555
Co-fractionation Homo sapiens
137 ELAVL2 1993
Affinity Capture-MS Homo sapiens
138 ACTN4 81
Co-fractionation Homo sapiens
139 HNRNPDL 9987
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
140 PAIP2B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
141 ECH1 1891
Co-fractionation Homo sapiens
142 GAN 8139
Affinity Capture-MS Homo sapiens
143 IMPA2 3613
Co-fractionation Homo sapiens
144 LARP1 23367
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
145 PNN 5411
Cross-Linking-MS (XL-MS) Homo sapiens
146 RPL3L 6123
Co-fractionation Homo sapiens
147 BCL2L2 599
Affinity Capture-MS Homo sapiens
148 NR4A1  
Affinity Capture-MS Homo sapiens
149 CLK3  
Affinity Capture-MS Homo sapiens
150 EMC8 10328
Affinity Capture-MS Homo sapiens
151 XPO1 7514
Affinity Capture-MS Homo sapiens
152 NUBP2 10101
Co-fractionation Homo sapiens
153 EIF4G1 1981
Co-fractionation Homo sapiens
154 ECT2 1894
Affinity Capture-MS Homo sapiens
155 YBX1 4904
Affinity Capture-MS Homo sapiens
156 SIRT7  
Affinity Capture-MS Homo sapiens
157 ZFC3H1 196441
Affinity Capture-MS Homo sapiens
158 PPA1 5464
Co-fractionation Homo sapiens
159 PLRG1 5356
Co-fractionation Homo sapiens
160 CTNNB1 1499
Affinity Capture-MS Homo sapiens
161 MEX3A  
Affinity Capture-RNA Homo sapiens
162 PRKAR1A 5573
Co-fractionation Homo sapiens
163 PAN3 255967
Affinity Capture-MS Homo sapiens
164 BAG1 573
Affinity Capture-MS Homo sapiens
165 CUL3 8452
Affinity Capture-MS Homo sapiens
166 YWHAZ 7534
Affinity Capture-MS Homo sapiens
167 BTF3 689
Affinity Capture-MS Homo sapiens
168 CSE1L 1434
Co-fractionation Homo sapiens
169 ARF6 382
Affinity Capture-MS Homo sapiens
170 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
171 EPRS 2058
Co-fractionation Homo sapiens
172 MYC  
Affinity Capture-MS Homo sapiens
173 RPL7 6129
Co-fractionation Homo sapiens
174 SUZ12  
Affinity Capture-MS Homo sapiens
175 SART1 9092
Co-fractionation Homo sapiens
176 FN1 2335
Affinity Capture-MS Homo sapiens
177 TROVE2 6738
Co-fractionation Homo sapiens
178 AURKB 9212
Affinity Capture-MS Homo sapiens
179 HNF4A  
Affinity Capture-MS Homo sapiens
180 MKRN1 23608
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
181 PRKACA 5566
Affinity Capture-MS Homo sapiens
182 AGO4  
Affinity Capture-MS Homo sapiens
183 NCAPH 23397
Affinity Capture-MS Homo sapiens
184 DCUN1D1 54165
Affinity Capture-MS Homo sapiens
185 EIF4E 1977
Co-fractionation Homo sapiens
186 IFIT1 3434
Affinity Capture-MS Homo sapiens
187 RPA3 6119
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
188 SMAD9  
Two-hybrid Homo sapiens
189 PTPN1 5770
Co-fractionation Homo sapiens
190 MAT2A 4144
Co-fractionation Homo sapiens
191 TRIM11  
Affinity Capture-MS Homo sapiens
192 PABPC5 140886
Cross-Linking-MS (XL-MS) Homo sapiens
193 NHP2L1 4809
Co-fractionation Homo sapiens
194 HSPA1A 3303
Co-fractionation Homo sapiens
195 SSB 6741
Affinity Capture-MS Homo sapiens
196 HIST1H1A 3024
Affinity Capture-MS Homo sapiens
197 SKIV2L2 23517
Co-fractionation Homo sapiens
198 STMN1 3925
Cross-Linking-MS (XL-MS) Homo sapiens
199 RPL18 6141
Co-fractionation Homo sapiens
200 DDRGK1 65992
Affinity Capture-MS Homo sapiens
201 RNF2  
Affinity Capture-MS Homo sapiens
202 BMI1  
Affinity Capture-MS Homo sapiens
203 HSPB1 3315
Co-fractionation Homo sapiens
204 XIRP2  
Cross-Linking-MS (XL-MS) Homo sapiens
205 FSCN1 6624
Affinity Capture-MS Homo sapiens
206 Ppp1cb 19046
Affinity Capture-MS Mus musculus
207 TSC22D3  
Affinity Capture-MS Homo sapiens
208 ZC3H3  
Affinity Capture-MS Homo sapiens
209 AKAP1 8165
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
210 RAE1 8480
Co-fractionation Homo sapiens
211 CCDC8  
Affinity Capture-MS Homo sapiens
212 PHGDH 26227
Co-fractionation Homo sapiens
213 G3BP1 10146
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
214 DSP 1832
Co-fractionation Homo sapiens
215 WDR77 79084
Affinity Capture-MS Homo sapiens
216 TTN 7273
Cross-Linking-MS (XL-MS) Homo sapiens
217 HSP90AA1 3320
Cross-Linking-MS (XL-MS) Homo sapiens
218 TBX3 6926
Affinity Capture-MS Homo sapiens
219 KRT18 3875
Co-fractionation Homo sapiens
220 DHX15 1665
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
221 PPT1 5538
Co-fractionation Homo sapiens
222 ARRB2 409
Affinity Capture-MS Homo sapiens
223 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
224 FBXW11  
Affinity Capture-MS Homo sapiens
225 SPOP  
Affinity Capture-MS Homo sapiens
226 TERF2  
Affinity Capture-MS Homo sapiens
227 LRPPRC 10128
Affinity Capture-MS Homo sapiens
228 RPS3 6188
Co-fractionation Homo sapiens
229 PREP 5550
Co-fractionation Homo sapiens
230 POLE  
Co-fractionation Homo sapiens
231 TP53 7157
Affinity Capture-MS Homo sapiens
232 RPL6 6128
Affinity Capture-MS Homo sapiens
233 LSM12 124801
Affinity Capture-MS Homo sapiens
234 WWOX 51741
Affinity Capture-MS Homo sapiens
235 APOBEC3D  
Affinity Capture-MS Homo sapiens
236 ZNF746  
Affinity Capture-MS Homo sapiens
237 ATG13 9776
Affinity Capture-MS Homo sapiens
238 RPA1 6117
Affinity Capture-MS Homo sapiens
239 GNB2L1 10399
Affinity Capture-MS Homo sapiens
240 CUL5 8065
Affinity Capture-MS Homo sapiens
241 PDCD6 10016
Co-fractionation Homo sapiens
242 EMC9  
Affinity Capture-MS Homo sapiens
243 MKRN3  
Affinity Capture-MS Homo sapiens
244 PRMT1 3276
Affinity Capture-MS Homo sapiens
245 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
246 CAPRIN1 4076
Affinity Capture-MS Homo sapiens
247 CAPZB 832
Affinity Capture-MS Homo sapiens
248 NSA2  
Affinity Capture-MS Homo sapiens
249 G3BP2 9908
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
250 PUF60 22827
Affinity Capture-MS Homo sapiens
251 GNL1 2794
Co-fractionation Homo sapiens
252 DDX58 23586
Affinity Capture-RNA Homo sapiens
253 MNDA 4332
Affinity Capture-MS Homo sapiens
254 CUL9  
Affinity Capture-MS Homo sapiens
255 ESR1  
Affinity Capture-MS Homo sapiens
256 PDZD8 118987
Affinity Capture-MS Homo sapiens
257 UFL1 23376
Affinity Capture-MS Homo sapiens
258 GSTM3 2947
Co-fractionation Homo sapiens
259 DDX39A 10212
Co-fractionation Homo sapiens
260 RPL39 6170
Co-fractionation Homo sapiens
261 RPS3A 6189
Co-fractionation Homo sapiens
262 NCAPD2 9918
Co-fractionation Homo sapiens
263 TERF1 7013
Affinity Capture-MS Homo sapiens
264 CHMP4C 92421
Affinity Capture-MS Homo sapiens
265 PABPC4L 132430
Affinity Capture-MS Homo sapiens
266 GAPDH 2597
Co-fractionation Homo sapiens
267 EZH2  
Affinity Capture-MS Homo sapiens
268 HNRNPL 3191
Co-fractionation Homo sapiens
269 PHLDA1 22822
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
270 ATG4B 23192
Affinity Capture-MS Homo sapiens
271 TRIM31  
Affinity Capture-MS Homo sapiens
272 PINK1  
Affinity Capture-MS Homo sapiens
273 IL7R  
Protein-RNA Homo sapiens
274 RBM8A 9939
Affinity Capture-MS Homo sapiens
275 RPL8 6132
Co-fractionation Homo sapiens
276 RPL27 6155
Co-fractionation Homo sapiens
277 EDC3 80153
Affinity Capture-MS Homo sapiens
278 SERBP1 26135
Proximity Label-MS Homo sapiens
279 CUL7 9820
Affinity Capture-MS Homo sapiens
280 ACE2 59272
Affinity Capture-MS Homo sapiens
281 HNRNPU 3192
Affinity Capture-MS Homo sapiens
282 SH3KBP1 30011
Affinity Capture-MS Homo sapiens
283 NUFIP2 57532
Affinity Capture-MS Homo sapiens
284 RC3H1 149041
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
285 DDX3X 1654
Affinity Capture-MS Homo sapiens
286 IVNS1ABP  
Affinity Capture-MS Homo sapiens
287 PAIP1 10605
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
288 IFIT2 3433
Affinity Capture-MS Homo sapiens
289 UBE2H 7328
Affinity Capture-MS Homo sapiens
290 CUL4A 8451
Affinity Capture-MS Homo sapiens
291 EP300 2033
Affinity Capture-MS Homo sapiens
292 EIF5 1983
Affinity Capture-MS Homo sapiens
293 HNRNPA2B1 3181
Co-fractionation Homo sapiens
294 C9orf72  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which PABPC4 is involved
No pathways found





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