Gene description for RPL27
Gene name ribosomal protein L27
Gene symbol RPL27
Other names/aliases L27
Species Homo sapiens
 Database cross references - RPL27
ExoCarta ExoCarta_6155
Vesiclepedia VP_6155
Entrez Gene 6155
HGNC 10328
MIM 607526
UniProt P61353  
 RPL27 identified in sEVs derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
B cells 20458337    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocytes 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for RPL27
Molecular Function
    RNA binding GO:0003723 HDA
    structural constituent of ribosome GO:0003735 IBA
    structural constituent of ribosome GO:0003735 IDA
    structural constituent of ribosome GO:0003735 NAS
    structural constituent of ribosome GO:0003735 TAS
    protein binding GO:0005515 IPI
Biological Process
    cytoplasmic translation GO:0002181 IC
    cytoplasmic translation GO:0002181 NAS
    rRNA processing GO:0006364 IMP
    translation GO:0006412 NAS
    response to aldosterone GO:1904044 IEA
Subcellular Localization
    nucleus GO:0005634 HDA
    nucleoplasm GO:0005654 IDA
    nucleolus GO:0005730 IDA
    cytoplasm GO:0005737 NAS
    cytosol GO:0005829 TAS
    ribosome GO:0005840 TAS
    focal adhesion GO:0005925 HDA
    membrane GO:0016020 HDA
    cytosolic large ribosomal subunit GO:0022625 HDA
    cytosolic large ribosomal subunit GO:0022625 IBA
    cytosolic large ribosomal subunit GO:0022625 IDA
    cytosolic large ribosomal subunit GO:0022625 IPI
    cytosolic ribosome GO:0022626 IDA
    synapse GO:0045202 IEA
    extracellular exosome GO:0070062 HDA
    cytoplasmic side of rough endoplasmic reticulum membrane GO:0098556 ISS
    ribonucleoprotein complex GO:1990904 IDA
 Experiment description of studies that identified RPL27 in sEVs
1
Experiment ID 79
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 80
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
3
Experiment ID 81
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
4
Experiment ID 489
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 490
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 491
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 492
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 412
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
9
Experiment ID 414
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
13
Experiment ID 498
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
14
Experiment ID 407
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
15
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
18
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
19
Experiment ID 405
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 235
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
24
Experiment ID 236
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
25
Experiment ID 237
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
26
Experiment ID 417
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 411
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 488
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
29
Experiment ID 418
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 418
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 224
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
32
Experiment ID 413
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
33
Experiment ID 211
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
34
Experiment ID 212
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
35
Experiment ID 406
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 415
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
37
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
38
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
39
Experiment ID 408
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
40
Experiment ID 409
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
41
Experiment ID 416
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
42
Experiment ID 834
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
43
Experiment ID 835
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
44
Experiment ID 410
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
45
Experiment ID 217
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RPL27
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RPSA 3921
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
2 SRP19 6728
Affinity Capture-MS Homo sapiens
3 RIT1 6016
Negative Genetic Homo sapiens
4 CRBN  
Affinity Capture-MS Homo sapiens
5 HDAC4  
Affinity Capture-MS Homo sapiens
6 RPL26L1 51121
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
7 SPRTN  
Affinity Capture-MS Homo sapiens
8 UBL4A 8266
Affinity Capture-MS Homo sapiens
9 QARS 5859
Co-fractionation Homo sapiens
10 RPS3A 6189
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
11 NDUFS1 4719
Co-fractionation Homo sapiens
12 EIF2S3 1968
Affinity Capture-MS Homo sapiens
13 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
14 RPL30 6156
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
15 PPIE 10450
Affinity Capture-MS Homo sapiens
16 TOP2B 7155
Cross-Linking-MS (XL-MS) Homo sapiens
17 SSB 6741
Affinity Capture-MS Homo sapiens
18 ABCB5  
Cross-Linking-MS (XL-MS) Homo sapiens
19 CSNK1A1 1452
Affinity Capture-MS Homo sapiens
20 RPL13A 23521
Co-fractionation Homo sapiens
21 RPL37A 6168
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
22 G3BP1 10146
Affinity Capture-MS Homo sapiens
23 RPS19 6223
Co-fractionation Homo sapiens
24 RPL10 6134
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
25 RPL15 6138
Co-fractionation Homo sapiens
26 RPL14 9045
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
27 CSNK2A1 1457
Affinity Capture-MS Homo sapiens
28 DNAJC25 548645
Affinity Capture-MS Homo sapiens
29 CAND1 55832
Affinity Capture-MS Homo sapiens
30 ZBTB1  
Affinity Capture-MS Homo sapiens
31 NOC2L 26155
Co-fractionation Homo sapiens
32 DNAJC15  
Affinity Capture-MS Homo sapiens
33 SOX2  
Affinity Capture-MS Homo sapiens
34 RPS3 6188
Co-fractionation Homo sapiens
35 RPL3L 6123
Co-fractionation Homo sapiens
36 RB1CC1 9821
Affinity Capture-MS Homo sapiens
37 PPP1CC 5501
Affinity Capture-MS Homo sapiens
38 RPS18 6222
Co-fractionation Homo sapiens
39 CAPZB 832
Affinity Capture-MS Homo sapiens
40 METAP2 10988
Affinity Capture-MS Homo sapiens
41 RPL4 6124
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
42 RPS20 6224
Co-fractionation Homo sapiens
43 FBXW7  
Affinity Capture-MS Homo sapiens
44 BTF3 689
Affinity Capture-MS Homo sapiens
45 PRC1 9055
Affinity Capture-MS Homo sapiens
46 PSMA3 5684
Cross-Linking-MS (XL-MS) Homo sapiens
47 KIF23 9493
Affinity Capture-MS Homo sapiens
48 MCM2 4171
Affinity Capture-MS Homo sapiens
49 SF3B1 23451
Cross-Linking-MS (XL-MS) Homo sapiens
50 AP1G1 164
Cross-Linking-MS (XL-MS) Homo sapiens
51 COPS5 10987
Affinity Capture-MS Homo sapiens
52 SMYD3 64754
Affinity Capture-MS Homo sapiens
53 RPL24 6152
Co-fractionation Homo sapiens
54 RPL18 6141
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
55 PSMD9 5715
Affinity Capture-MS Homo sapiens
56 NPM1 4869
Affinity Capture-MS Homo sapiens
57 RPS9 6203
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
58 MYCN  
Affinity Capture-MS Homo sapiens
59 GSPT1 2935
Affinity Capture-MS Homo sapiens
60 ADARB1 104
Affinity Capture-MS Homo sapiens
61 PRKRA 8575
Affinity Capture-MS Homo sapiens
62 DNAJC16  
Affinity Capture-MS Homo sapiens
63 SRP68 6730
Affinity Capture-MS Homo sapiens
64 RPL29 6159
Co-fractionation Homo sapiens
65 DDX18 8886
Co-fractionation Homo sapiens
66 ATG16L1 55054
Affinity Capture-MS Homo sapiens
67 DDX6 1656
Affinity Capture-MS Homo sapiens
68 SUGCT  
Cross-Linking-MS (XL-MS) Homo sapiens
69 ZNF346  
Affinity Capture-MS Homo sapiens
70 RPS26 6231
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
71 MECP2 4204
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 Eif3a 13669
Affinity Capture-MS Mus musculus
73 CUL1 8454
Affinity Capture-MS Homo sapiens
74 TFCP2 7024
Affinity Capture-MS Homo sapiens
75 ARIH2 10425
Affinity Capture-MS Homo sapiens
76 RBM42  
Affinity Capture-MS Homo sapiens
77 RPS11 6205
Co-fractionation Homo sapiens
78 PABPC4 8761
Co-fractionation Homo sapiens
79 RPL19 6143
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
80 SLC25A3 5250
Co-fractionation Homo sapiens
81 CTCF  
Affinity Capture-MS Homo sapiens
82 KIF14 9928
Affinity Capture-MS Homo sapiens
83 GAR1 54433
Affinity Capture-MS Homo sapiens
84 PES1 23481
Co-fractionation Homo sapiens
85 FOXP1 27086
Protein-RNA Homo sapiens
86 LIN28A  
Affinity Capture-MS Homo sapiens
87 EMC9  
Affinity Capture-MS Homo sapiens
88 MRE11A 4361
Co-fractionation Homo sapiens
89 PDZD8 118987
Affinity Capture-MS Homo sapiens
90 BRIX1 55299
Co-fractionation Homo sapiens
91 TSHZ2  
Cross-Linking-MS (XL-MS) Homo sapiens
92 CHMP4C 92421
Affinity Capture-MS Homo sapiens
93 AURKA 6790
Affinity Capture-MS Homo sapiens
94 RPL27 6155
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
95 SRP9 6726
Affinity Capture-MS Homo sapiens
96 DLD 1738
Affinity Capture-MS Homo sapiens
97 KIAA0020 9933
Affinity Capture-MS Homo sapiens
98 SPANXN2  
Two-hybrid Homo sapiens
99 FOXA1  
Affinity Capture-MS Homo sapiens
100 RPL27A 6157
Co-fractionation Homo sapiens
101 COX15 1355
Affinity Capture-MS Homo sapiens
102 DDX21 9188
Affinity Capture-MS Homo sapiens
103 FUT8 2530
Co-fractionation Homo sapiens
104 RPL9 6133
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
105 BMP4 652
Affinity Capture-MS Homo sapiens
106 CUL4B 8450
Affinity Capture-MS Homo sapiens
107 PARK2  
Affinity Capture-MS Homo sapiens
108 RPS10 6204
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
109 MSX2  
Affinity Capture-MS Homo sapiens
110 C17orf85  
Affinity Capture-MS Homo sapiens
111 TUBGCP4 27229
Affinity Capture-MS Homo sapiens
112 HIST1H3E 8353
Affinity Capture-MS Homo sapiens
113 VRK1 7443
Affinity Capture-MS Homo sapiens
114 RPL5 6125
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
115 RPL18A 6142
Co-fractionation Homo sapiens
116 PABPC1 26986
Co-fractionation Homo sapiens
117 CHMP4B 128866
Affinity Capture-MS Homo sapiens
118 YAP1 10413
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
119 TRIM21 6737
Affinity Capture-MS Homo sapiens
120 RPL31 6160
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
121 RPS7 6201
Co-fractionation Homo sapiens
122 RPS24 6229
Co-fractionation Homo sapiens
123 ARNT 405
Affinity Capture-MS Homo sapiens
124 RLIM 51132
Affinity Capture-MS Homo sapiens
125 API5 8539
Affinity Capture-MS Homo sapiens
126 RPL36 25873
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
127 EVPL 2125
Co-fractionation Homo sapiens
128 RPLP1 6176
Co-fractionation Homo sapiens
129 DDX1 1653
Co-fractionation Homo sapiens
130 DHX9 1660
Co-fractionation Homo sapiens
131 HECTD1 25831
Affinity Capture-MS Homo sapiens
132 RIN3  
Affinity Capture-MS Homo sapiens
133 RPLP0 6175
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
134 RPLP0P6 220717
Co-fractionation Homo sapiens
135 MAGEB2 4113
Affinity Capture-MS Homo sapiens
136 TRIM31  
Affinity Capture-MS Homo sapiens
137 MYBBP1A 10514
Affinity Capture-MS Homo sapiens
138 Ksr1  
Affinity Capture-MS Mus musculus
139 GTPBP4 23560
Co-fractionation Homo sapiens
140 CYLD  
Affinity Capture-MS Homo sapiens
141 LOC101929876 101929876
Co-fractionation Homo sapiens
142 HMGB2 3148
Affinity Capture-MS Homo sapiens
143 RRS1 23212
Affinity Capture-MS Homo sapiens
144 CNBP 7555
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
145 ANLN 54443
Affinity Capture-MS Homo sapiens
146 NEDD1 121441
Affinity Capture-MS Homo sapiens
147 TMPO 7112
Affinity Capture-MS Homo sapiens
148 RPL32 6161
Co-fractionation Homo sapiens
149 RPS17 6218
Co-fractionation Homo sapiens
150 RBM39 9584
Affinity Capture-MS Homo sapiens
151 EFNA4  
Affinity Capture-MS Homo sapiens
152 RPS29 6235
Co-fractionation Homo sapiens
153 RPLP2 6181
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
154 FANCD2  
Affinity Capture-MS Homo sapiens
155 ABT1 29777
Affinity Capture-MS Homo sapiens
156 METTL14  
Affinity Capture-MS Homo sapiens
157 RPL7A 6130
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
158 MRTO4 51154
Co-fractionation Homo sapiens
159 RPS2 6187
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
160 UBE2H 7328
Affinity Capture-MS Homo sapiens
161 RC3H2  
Affinity Capture-MS Homo sapiens
162 ECT2 1894
Affinity Capture-MS Homo sapiens
163 DNAJC2 27000
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
164 RPL35 11224
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
165 AHNAK 79026
Cross-Linking-MS (XL-MS) Homo sapiens
166 UBE2L6 9246
Affinity Capture-MS Homo sapiens
167 NPM3 10360
Affinity Capture-MS Homo sapiens
168 USP36  
Affinity Capture-MS Homo sapiens
169 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
170 RPS8 6202
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
171 RPL21 6144
Co-fractionation Homo sapiens
172 RPL3 6122
Co-fractionation Homo sapiens
173 EBNA1BP2 10969
Affinity Capture-MS Homo sapiens
174 FAM90A1  
Affinity Capture-MS Homo sapiens
175 MYC  
Affinity Capture-MS Homo sapiens
176 ANP32E 81611
Cross-Linking-MS (XL-MS) Homo sapiens
177 NTHL1  
Affinity Capture-MS Homo sapiens
178 AURKB 9212
Affinity Capture-MS Homo sapiens
179 RPS27 6232
Co-fractionation Homo sapiens
180 CDK2 1017
Affinity Capture-MS Homo sapiens
181 CEP250 11190
Affinity Capture-MS Homo sapiens
182 AGO4  
Affinity Capture-MS Homo sapiens
183 NCAPH 23397
Affinity Capture-MS Homo sapiens
184 SOAT1 6646
Affinity Capture-MS Homo sapiens
185 PCBP1 5093
Affinity Capture-MS Homo sapiens
186 RPL17 6139
Co-fractionation Homo sapiens
187 PSPC1 55269
Affinity Capture-MS Homo sapiens
188 BAG1 573
Affinity Capture-MS Homo sapiens
189 RPS13 6207
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
190 RPS6 6194
Co-fractionation Homo sapiens
191 INO80B 83444
Affinity Capture-MS Homo sapiens
192 EGFR 1956
Negative Genetic Homo sapiens
193 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
194 RPS14 6208
Co-fractionation Homo sapiens
195 RPL35A 6165
Co-fractionation Homo sapiens
196 RPL12 6136
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
197 RPA4  
Proximity Label-MS Homo sapiens
198 RPL22 6146
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
199 SART3 9733
Affinity Capture-MS Homo sapiens
200 PPP6C 5537
Affinity Capture-MS Homo sapiens
201 RPL23A 6147
Co-fractionation Homo sapiens
202 FLII 2314
Co-fractionation Homo sapiens
203 DDRGK1 65992
Affinity Capture-MS Homo sapiens
204 RNF2  
Affinity Capture-MS Homo sapiens
205 VDAC1 7416
Affinity Capture-MS Homo sapiens
206 Rpl35 66489
Affinity Capture-MS Mus musculus
207 RPL11 6135
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
208 RPL7 6129
Co-fractionation Homo sapiens
209 Eif3e 16341
Affinity Capture-MS Mus musculus
210 RPL26 6154
Co-fractionation Homo sapiens
211 CHUK 1147
Two-hybrid Homo sapiens
212 C9orf72  
Affinity Capture-MS Homo sapiens
213 HUWE1 10075
Affinity Capture-MS Homo sapiens
214 RPS16 6217
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
215 PA2G4 5036
Affinity Capture-MS Homo sapiens
216 RPL13 6137
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
217 RPL37 6167
Co-fractionation Homo sapiens
218 ENY2 56943
Affinity Capture-MS Homo sapiens
219 NRP1 8829
Two-hybrid Homo sapiens
220 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
221 PSMB10 5699
Affinity Capture-MS Homo sapiens
222 RPS25 6230
Co-fractionation Homo sapiens
223 PARP1 142
Proximity Label-MS Homo sapiens
224 BKRF1  
Affinity Capture-MS
225 ILF3 3609
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
226 CUL2 8453
Affinity Capture-MS Homo sapiens
227 DNAJC19 131118
Affinity Capture-MS Homo sapiens
228 RPL10L 140801
Co-fractionation Homo sapiens
229 TP53 7157
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
230 RPL6 6128
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
231 FOLR1 2348
Affinity Capture-MS Homo sapiens
232 RPS21 6227
Co-fractionation Homo sapiens
233 ATG13 9776
Affinity Capture-MS Homo sapiens
234 CDK11B 984
Co-fractionation Homo sapiens
235 TPT1 7178
Affinity Capture-MS Homo sapiens
236 CUL5 8065
Affinity Capture-MS Homo sapiens
237 RPS12 6206
Co-fractionation Homo sapiens
238 Pard6b  
Affinity Capture-MS Mus musculus
239 KNOP1 400506
Affinity Capture-MS Homo sapiens
240 HNRNPM 4670
Co-fractionation Homo sapiens
241 RPS4X 6191
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
242 ZNF48  
Affinity Capture-MS Homo sapiens
243 RPS15 6209
Co-fractionation Homo sapiens
244 HSPA5 3309
Cross-Linking-MS (XL-MS) Homo sapiens
245 SRP72 6731
Affinity Capture-MS Homo sapiens
246 CAPRIN1 4076
Affinity Capture-MS Homo sapiens
247 TKT 7086
Cross-Linking-MS (XL-MS) Homo sapiens
248 NSA2  
Co-fractionation Homo sapiens
249 G3BP2 9908
Affinity Capture-MS Homo sapiens
250 RPS5 6193
Co-fractionation Homo sapiens
251 RPS15A 6210
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
252 RPL34 6164
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
253 TOP2A 7153
Affinity Capture-MS Homo sapiens
254 COL6A6 131873
Cross-Linking-MS (XL-MS) Homo sapiens
255 DRG1 4733
Affinity Capture-MS Homo sapiens
256 UFL1 23376
Affinity Capture-MS Homo sapiens
257 RPL10A 4736
Co-fractionation Homo sapiens
258 COQ2  
Affinity Capture-MS Homo sapiens
259 DNM1L 10059
Affinity Capture-MS Homo sapiens
260 SETD8  
Affinity Capture-MS Homo sapiens
261 RPL38 6169
Co-fractionation Homo sapiens
262 PPP1R12A 4659
Cross-Linking-MS (XL-MS) Homo sapiens
263 NCL 4691
Affinity Capture-MS Homo sapiens
264 SEC61B 10952
Affinity Capture-MS Homo sapiens
265 IL17B 27190
Affinity Capture-MS Homo sapiens
266 RPS23 6228
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
267 RTCB 51493
Co-fractionation Homo sapiens
268 ATG4B 23192
Affinity Capture-MS Homo sapiens
269 RPL23 9349
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
270 PINK1  
Affinity Capture-MS Homo sapiens
271 RBM8A 9939
Affinity Capture-MS Homo sapiens
272 Rrbp1  
Affinity Capture-MS Mus musculus
273 RPL8 6132
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
274 RPL28 6158
Affinity Capture-MS Homo sapiens
275 DNAJC1 64215
Affinity Capture-MS Homo sapiens
276 KRAS 3845
Negative Genetic Homo sapiens
277 HNRNPU 3192
Affinity Capture-MS Homo sapiens
278 GNB2L1 10399
Affinity Capture-MS Homo sapiens
279 RPL36AL 6166
Affinity Capture-MS Homo sapiens
280 RC3H1 149041
Affinity Capture-MS Homo sapiens
281 IGF2BP3 10643
Cross-Linking-MS (XL-MS) Homo sapiens
282 MATN2 4147
Affinity Capture-MS Homo sapiens
283 RPA3 6119
Proximity Label-MS Homo sapiens
284 REPIN1  
Affinity Capture-MS Homo sapiens
285 DDX56  
Co-fractionation Homo sapiens
286 H1FOO 132243
Affinity Capture-MS Homo sapiens
287 CUL4A 8451
Affinity Capture-MS Homo sapiens
288 EP300 2033
Two-hybrid Homo sapiens
289 SP3  
Cross-Linking-MS (XL-MS) Homo sapiens
View the network image/svg+xml
 Pathways in which RPL27 is involved
PathwayEvidenceSource
Axon guidance IEA Reactome
Cap-dependent Translation Initiation TAS Reactome
Cellular response to starvation IEA Reactome
Cellular responses to stimuli IEA Reactome
Cellular responses to stress IEA Reactome
Developmental Biology IEA Reactome
Disease TAS Reactome
Eukaryotic Translation Elongation IEA Reactome
Eukaryotic Translation Initiation TAS Reactome
Eukaryotic Translation Termination IEA Reactome
Formation of a pool of free 40S subunits TAS Reactome
GTP hydrolysis and joining of the 60S ribosomal subunit TAS Reactome
Infectious disease TAS Reactome
Influenza Infection TAS Reactome
Influenza Viral RNA Transcription and Replication TAS Reactome
L13a-mediated translational silencing of Ceruloplasmin expression TAS Reactome
Major pathway of rRNA processing in the nucleolus and cytosol TAS Reactome
Metabolism IEA Reactome
Metabolism of amino acids and derivatives IEA Reactome
Metabolism of proteins TAS Reactome
Metabolism of proteins IEA Reactome
Metabolism of RNA TAS Reactome
Nervous system development IEA Reactome
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) TAS Reactome
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) TAS Reactome
Nonsense-Mediated Decay (NMD) TAS Reactome
Peptide chain elongation IEA Reactome
Regulation of expression of SLITs and ROBOs IEA Reactome
Response of EIF2AK4 (GCN2) to amino acid deficiency IEA Reactome
rRNA processing TAS Reactome
rRNA processing in the nucleus and cytosol TAS Reactome
Selenoamino acid metabolism IEA Reactome
Selenocysteine synthesis IEA Reactome
Signaling by ROBO receptors IEA Reactome
SRP-dependent cotranslational protein targeting to membrane IEA Reactome
SRP-dependent cotranslational protein targeting to membrane TAS Reactome
Translation TAS Reactome
Translation IEA Reactome
Viral Infection Pathways TAS Reactome
Viral mRNA Translation TAS Reactome





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