Gene description for PPP5C
Gene name protein phosphatase 5, catalytic subunit
Gene symbol PPP5C
Other names/aliases PP5
PPP5
PPT
Species Homo sapiens
 Database cross references - PPP5C
ExoCarta ExoCarta_5536
Vesiclepedia VP_5536
Entrez Gene 5536
HGNC 9322
MIM 600658
UniProt P53041  
 PPP5C identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Mesenchymal stem cells 36408942    
Neuroblastoma cells 25944692    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
 Gene ontology annotations for PPP5C
Molecular Function
    RNA binding GO:0003723 IEA
    phosphoprotein phosphatase activity GO:0004721 ISS
    phosphoprotein phosphatase activity GO:0004721 TAS
    protein serine/threonine phosphatase activity GO:0004722 IBA
    protein serine/threonine phosphatase activity GO:0004722 IDA
    protein serine/threonine phosphatase activity GO:0004722 ISS
    protein serine/threonine phosphatase activity GO:0004722 TAS
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IDA
    lipid binding GO:0008289 IEA
    phosphatase activity GO:0016791 IDA
    myosin phosphatase activity GO:0017018 IEA
    calmodulin-dependent protein phosphatase activity GO:0033192 IEA
    identical protein binding GO:0042802 IPI
    ADP binding GO:0043531 IDA
    metal ion binding GO:0046872 IEA
    tau protein binding GO:0048156 NAS
    Hsp90 protein binding GO:0051879 IPI
    histone H2AXS140 phosphatase activity GO:0140791 IEA
    RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity GO:0180004 IEA
    RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity GO:0180005 IEA
    RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity GO:0180006 IEA
    RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity GO:0180007 IEA
    RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity GO:0180008 IEA
    MAP kinase serine/threonine phosphatase activity GO:1990439 IEA
Biological Process
    MAPK cascade GO:0000165 TAS
    mitotic cell cycle GO:0000278 TAS
    double-strand break repair GO:0006302 TAS
    chromatin remodeling GO:0006338 IEA
    DNA-templated transcription GO:0006351 TAS
    regulation of transcription by RNA polymerase II GO:0006357 IEA
    protein dephosphorylation GO:0006470 TAS
    response to lead ion GO:0010288 ISS
    peptidyl-threonine dephosphorylation GO:0035970 TAS
    positive regulation of canonical NF-kappaB signal transduction GO:0043123 HMP
    response to morphine GO:0043278 IEA
    peptidyl-serine dephosphorylation GO:0070262 IDA
    peptidyl-serine dephosphorylation GO:0070262 TAS
    response to arachidonate GO:1904550 ISS
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleoplasm GO:0005654 TAS
    cytosol GO:0005829 IBA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    plasma membrane GO:0005886 IEA
    protein-containing complex GO:0032991 IDA
    intracellular membrane-bounded organelle GO:0043231 IDA
    protein folding chaperone complex GO:0101031 IDA
 Experiment description of studies that identified PPP5C in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
6
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
9
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
12
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
13
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PPP5C
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 HACD3 51495
Affinity Capture-MS Homo sapiens
3 NUDC 10726
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
4 BPHL 670
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 GNA12 2768
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
6 DNAJC11 55735
Affinity Capture-MS Homo sapiens
7 CDC42BPB 9578
Affinity Capture-MS Homo sapiens
8 DNAJC8 22826
Affinity Capture-MS Homo sapiens
9 HSPA6 3310
Affinity Capture-MS Homo sapiens
10 DUSP8  
Affinity Capture-MS Homo sapiens
11 BZW2 28969
Co-fractionation Homo sapiens
12 CCT4 10575
Affinity Capture-MS Homo sapiens
13 HSP90AB1 3326
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
14 CSE1L 1434
Two-hybrid Homo sapiens
15 PGR  
Affinity Capture-Western Homo sapiens
16 APP 351
Reconstituted Complex Homo sapiens
17 MAP3K5 4217
Affinity Capture-Western Homo sapiens
Phenotypic Suppression Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
18 LRRC1 55227
Affinity Capture-MS Homo sapiens
19 AHSG 197
Co-fractionation Homo sapiens
20 AGO3  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
21 FSCN3  
Affinity Capture-MS Homo sapiens
22 STIP1 10963
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
23 PLD2 5338
Affinity Capture-MS Homo sapiens
24 CHORDC1 26973
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
25 CDC27 996
Reconstituted Complex Homo sapiens
26 YWHAB 7529
Affinity Capture-MS Homo sapiens
27 CTPS1 1503
Co-fractionation Homo sapiens
28 YAF2  
Affinity Capture-MS Homo sapiens
29 HSPA8 3312
Affinity Capture-MS Homo sapiens
30 ADSL 158
Co-fractionation Homo sapiens
31 LMAN1 3998
Proximity Label-MS Homo sapiens
32 XPO1 7514
Co-fractionation Homo sapiens
33 GADL1  
Affinity Capture-MS Homo sapiens
34 IRS4 8471
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
35 PPIB 5479
Co-fractionation Homo sapiens
36 PRPF8 10594
Affinity Capture-MS Homo sapiens
37 PARK2  
Affinity Capture-MS Homo sapiens
38 DUT 1854
Co-fractionation Homo sapiens
39 RAB41  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 TUFM 7284
Co-fractionation Homo sapiens
41 ABCF2 10061
Affinity Capture-MS Homo sapiens
42 RPS6KB1 6198
Affinity Capture-MS Homo sapiens
43 MAPT  
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
44 VCL 7414
Co-fractionation Homo sapiens
45 FUBP1 8880
Co-fractionation Homo sapiens
46 NTRK1 4914
Affinity Capture-MS Homo sapiens
47 MOV10 4343
Affinity Capture-RNA Homo sapiens
48 USP45  
Affinity Capture-MS Homo sapiens
49 YWHAQ 10971
Affinity Capture-MS Homo sapiens
50 ENO1 2023
Affinity Capture-RNA Homo sapiens
51 PIK3R1 5295
Affinity Capture-MS Homo sapiens
52 ABHD14A  
Co-fractionation Homo sapiens
53 DEF8  
Affinity Capture-MS Homo sapiens
54 CEBPA  
Protein-peptide Homo sapiens
55 PHLPP1  
Affinity Capture-MS Homo sapiens
56 DISC1 27185
Two-hybrid Homo sapiens
57 RBBP6 5930
Affinity Capture-MS Homo sapiens
58 OGT 8473
Reconstituted Complex Homo sapiens
59 RAP1GDS1 5910
Co-fractionation Homo sapiens
60 PAPSS1 9061
Co-fractionation Homo sapiens
61 CDK9 1025
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
62 TP53BP1 7158
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
63 PLA2G4A 5321
Affinity Capture-MS Homo sapiens
64 EIF6 3692
Co-fractionation Homo sapiens
65 BAG2 9532
Affinity Capture-MS Homo sapiens
66 CNTLN 54875
Affinity Capture-MS Homo sapiens
67 Itgb1bp2  
Reconstituted Complex Mus musculus
68 IKBKAP 8518
Affinity Capture-MS Homo sapiens
69 ELP3 55140
Affinity Capture-MS Homo sapiens
70 NR3C1 2908
Affinity Capture-Western Homo sapiens
71 EGFR 1956
PCA Homo sapiens
72 DCPS 28960
Co-fractionation Homo sapiens
73 HNRNPA1 3178
Co-fractionation Homo sapiens
74 HSP90AA5P 730211
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
75 MAP3K7  
Two-hybrid Homo sapiens
76 RIPK4  
Affinity Capture-MS Homo sapiens
77 NXF1 10482
Affinity Capture-RNA Homo sapiens
78 GINS3  
Co-fractionation Homo sapiens
79 FKBP5 2289
Affinity Capture-MS Homo sapiens
80 PSPC1 55269
Co-fractionation Homo sapiens
81 RPA3 6119
Proximity Label-MS Homo sapiens
82 DIS3 22894
Co-fractionation Homo sapiens
83 TATDN1 83940
Co-fractionation Homo sapiens
84 HSPA4 3308
Affinity Capture-MS Homo sapiens
85 CDK20  
Reconstituted Complex Homo sapiens
86 DDB1 1642
Affinity Capture-MS Homo sapiens
87 GNA13 10672
Reconstituted Complex Homo sapiens
88 FLII 2314
Affinity Capture-MS Homo sapiens
89 DNAJB13  
Affinity Capture-MS Homo sapiens
90 SNRNP200 23020
Affinity Capture-MS Homo sapiens
91 CRY2  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
92 GRB2 2885
Affinity Capture-MS Homo sapiens
93 PSEN2 5664
Affinity Capture-MS Homo sapiens
94 AHSA1 10598
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
95 SUGT1 10910
Affinity Capture-MS Homo sapiens
96 NAPRT 93100
Co-fractionation Homo sapiens
97 Chordc1  
Reconstituted Complex Mus musculus
Reconstituted Complex Mus musculus
98 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
99 ESR2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
100 USP49 25862
Affinity Capture-MS Homo sapiens
101 FBXL6  
Affinity Capture-MS Homo sapiens
102 GSS 2937
Co-fractionation Homo sapiens
103 AGO1  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
104 NOL10  
Co-fractionation Homo sapiens
105 PAFAH1B2 5049
Co-fractionation Homo sapiens
106 TPTE  
Affinity Capture-MS Homo sapiens
107 DFFA 1676
Co-fractionation Homo sapiens
108 CDC37 11140
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
109 CDK18 5129
Affinity Capture-MS Homo sapiens
110 NR3C2  
Affinity Capture-Western Homo sapiens
111 FAM83F 113828
Affinity Capture-MS Homo sapiens
112 HSP90AA1 3320
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
113 SHMT2 6472
Affinity Capture-RNA Homo sapiens
114 Map3k6  
Two-hybrid Mus musculus
115 FLCN 201163
Affinity Capture-Western Homo sapiens
116 ESR1  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
117 PLD3 23646
Co-fractionation Homo sapiens
118 EEF1A1P5 158078
Cross-Linking-MS (XL-MS) Homo sapiens
119 GAPDH 2597
Co-fractionation Homo sapiens
120 MINPP1 9562
Co-fractionation Homo sapiens
121 CAD 790
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
122 RXRA 6256
Co-fractionation Homo sapiens
123 RBBP5 5929
Affinity Capture-MS Homo sapiens
124 BRD1 23774
Affinity Capture-MS Homo sapiens
125 CDC37L1  
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
126 PTGES3 10728
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
127 GNB2L1 10399
Affinity Capture-MS Homo sapiens
128 AR 367
Affinity Capture-Western Homo sapiens
129 HSP90AB4P 664618
Affinity Capture-MS Homo sapiens
130 NOL9 79707
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
131 POLD2 5425
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
132 HSPA1B 3304
Affinity Capture-MS Homo sapiens
133 INTU  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here