Gene description for Hnrnph1
Gene name heterogeneous nuclear ribonucleoprotein H1
Gene symbol Hnrnph1
Other names/aliases AI642080
E430005G16Rik
Hnrnph
Hnrph1
Species Mus musculus
 Database cross references - Hnrnph1
ExoCarta ExoCarta_59013
Vesiclepedia VP_59013
Entrez Gene 59013
UniProt O35737  
 Hnrnph1 identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Hnrnph1
Molecular Function
    RNA binding GO:0003723 IBA
    RNA binding GO:0003723 ISO
    RNA binding GO:0003723 ISS
    protein binding GO:0005515 IPI
    enzyme binding GO:0019899 ISO
    identical protein binding GO:0042802 ISO
Biological Process
    mRNA processing GO:0006397 IEA
    RNA splicing GO:0008380 IEA
    regulation of RNA splicing GO:0043484 IBA
    regulation of RNA splicing GO:0043484 ISO
    regulation of RNA splicing GO:0043484 ISS
    cellular response to interleukin-7 GO:0098761 IDA
Subcellular Localization
    nucleus GO:0005634 ISO
    nucleus GO:0005634 ISS
    nucleoplasm GO:0005654 IBA
    nucleoplasm GO:0005654 IEA
    nucleoplasm GO:0005654 ISO
    spliceosomal complex GO:0005681 IEA
    cytosol GO:0005829 ISO
    postsynaptic density GO:0014069 ISO
    catalytic step 2 spliceosome GO:0071013 ISO
    ribonucleoprotein complex GO:1990904 IBA
 Experiment description of studies that identified Hnrnph1 in sEVs
1
Experiment ID 907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Hnrnph1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HNRNPH1 3187
Affinity Capture-MS Homo sapiens
2 Ddx5 13207
Affinity Capture-Western Mus musculus
3 Snrpd1 20641
Co-fractionation Mus musculus
4 Stau1  
Co-fractionation Mus musculus
5 WDR77 79084
Affinity Capture-MS Homo sapiens
6 Prpf8 192159
Co-fractionation Mus musculus
7 Plrg1  
Co-fractionation Mus musculus
8 Snrpd2 107686
Co-fractionation Mus musculus
9 ELAVL4  
Reconstituted Complex Homo sapiens
10 Kctd13  
Affinity Capture-MS Mus musculus
11 Ykt6 56418
Co-fractionation Mus musculus
12 Tfe3  
Affinity Capture-MS Mus musculus
13 Snrnp200 320632
Co-fractionation Mus musculus
14 Tia1  
Affinity Capture-Western Mus musculus
15 PLOD1 5351
Affinity Capture-MS Homo sapiens
16 Sf3a1 67465
Co-fractionation Mus musculus
17 PRMT5 10419
Affinity Capture-MS Homo sapiens
18 Iqcb1  
Affinity Capture-MS Mus musculus
19 Mecp2  
Affinity Capture-MS Mus musculus
20 Snrpd3 67332
Co-fractionation Mus musculus
21 Ighmbp2 20589
Affinity Capture-MS Mus musculus
22 Sf3b3 101943
Co-fractionation Mus musculus
23 Lsm3  
Co-fractionation Mus musculus
24 Tardbp 230908
Affinity Capture-Western Mus musculus
Co-fractionation Mus musculus
Affinity Capture-Western Mus musculus
25 Srsf1 110809
Co-fractionation Mus musculus
26 Hnrnpc 15381
Co-fractionation Mus musculus
27 Srrm2  
Co-fractionation Mus musculus
28 Unk  
Affinity Capture-RNA Mus musculus
29 Syncrip 56403
Co-fractionation Mus musculus
30 Snw1  
Co-fractionation Mus musculus
31 Ppwd1  
Co-fractionation Mus musculus
32 Zbtb7b  
Affinity Capture-MS Mus musculus
33 Lnx1  
Affinity Capture-MS Mus musculus
34 SNW1 22938
Two-hybrid Homo sapiens
35 Eed  
Affinity Capture-MS Mus musculus
36 Nlrp3  
Affinity Capture-MS Mus musculus
37 Ptbp1 19205
Co-fractionation Mus musculus
38 Skiv2l2  
Co-fractionation Mus musculus
39 Tcerg1  
Co-fractionation Mus musculus
40 Atg12  
Negative Genetic Mus musculus
41 Fancd2  
Affinity Capture-MS Mus musculus
42 Ptbp2  
Co-fractionation Mus musculus
43 Fus  
Affinity Capture-Western Mus musculus
View the network image/svg+xml



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