Gene description for BRD9
Gene name bromodomain containing 9
Gene symbol BRD9
Other names/aliases LAVS3040
PRO9856
Species Homo sapiens
 Database cross references - BRD9
ExoCarta ExoCarta_65980
Vesiclepedia VP_65980
Entrez Gene 65980
HGNC 25818
UniProt Q9H8M2  
 BRD9 identified in sEVs derived from the following tissue/cell type
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
 Gene ontology annotations for BRD9
Molecular Function
    nucleic acid binding GO:0003676 NAS
    protein binding GO:0005515 IPI
    lysine-acetylated histone binding GO:0070577 IBA
    lysine-acetylated histone binding GO:0070577 IDA
Biological Process
    chromatin remodeling GO:0006338 NAS
    regulation of transcription by RNA polymerase II GO:0006357 IBA
    regulation of transcription by RNA polymerase II GO:0006357 NAS
    positive regulation of cell population proliferation GO:0008284 NAS
    negative regulation of cell differentiation GO:0045596 NAS
    positive regulation of stem cell population maintenance GO:1902459 NAS
Subcellular Localization
    chromatin GO:0000785 NAS
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    SWI/SNF complex GO:0016514 IDA
    GBAF complex GO:0140288 NAS
 Experiment description of studies that identified BRD9 in sEVs
1
Experiment ID 834
MISEV standards
EM
Biophysical techniques
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 835
MISEV standards
EM
Biophysical techniques
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for BRD9
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ATG16L1 55054
Affinity Capture-MS Homo sapiens
2 LBR 3930
Affinity Capture-MS Homo sapiens
3 GLTSCR1L  
Affinity Capture-MS Homo sapiens
4 SLC25A13 10165
Affinity Capture-MS Homo sapiens
5 MAPKAPK2 9261
Affinity Capture-MS Homo sapiens
6 MYCN  
Affinity Capture-MS Homo sapiens
7 SMARCB1 6598
Affinity Capture-MS Homo sapiens
8 SMARCA2 6595
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 ARID2  
Affinity Capture-MS Homo sapiens
10 STK11IP 114790
Affinity Capture-MS Homo sapiens
11 CATIP  
Two-hybrid Homo sapiens
12 MUS81  
Synthetic Growth Defect Homo sapiens
13 MSH6 2956
Affinity Capture-MS Homo sapiens
14 NFE2L1  
Affinity Capture-MS Homo sapiens
15 BCL7A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 SMARCD1 6602
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 RIN3  
Affinity Capture-MS Homo sapiens
18 ECT2 1894
Affinity Capture-MS Homo sapiens
19 ARID1B 57492
Affinity Capture-MS Homo sapiens
20 DNAJA2 10294
Affinity Capture-MS Homo sapiens
21 PPARG 5468
Proximity Label-MS Homo sapiens
22 SMARCC1 6599
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 TCOF1 6949
Affinity Capture-MS Homo sapiens
24 PBRM1 55193
Affinity Capture-MS Homo sapiens
25 ACTC1 70
Affinity Capture-MS Homo sapiens
26 BRD7  
Affinity Capture-MS Homo sapiens
27 SMARCE1 6605
Affinity Capture-MS Homo sapiens
28 BRD2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
29 CSNK2A1 1457
Affinity Capture-MS Homo sapiens
30 PSME3 10197
Affinity Capture-MS Homo sapiens
31 PARK2  
Affinity Capture-MS Homo sapiens
32 PGAM5 192111
Affinity Capture-MS Homo sapiens
33 SMARCD2 6603
Affinity Capture-MS Homo sapiens
34 GLTSCR1 29998
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 SLC16A1 6566
Affinity Capture-MS Homo sapiens
36 SS18  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 DPF1  
Affinity Capture-MS Homo sapiens
38 CXXC4 80319
Affinity Capture-MS Homo sapiens
39 SLC25A11 8402
Affinity Capture-MS Homo sapiens
40 OTUD1 220213
Affinity Capture-MS Homo sapiens
41 SMARCA4 6597
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
42 RNPS1 10921
Affinity Capture-MS Homo sapiens
43 CHMP4B 128866
Affinity Capture-MS Homo sapiens
44 SS18L2  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
45 RPA3 6119
Proximity Label-MS Homo sapiens
46 BCL7C  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 DPF2  
Affinity Capture-MS Homo sapiens
48 NOLC1 9221
Affinity Capture-MS Homo sapiens
49 ACTL6A 86
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 ZCCHC10  
Affinity Capture-MS Homo sapiens
51 DPF3  
Affinity Capture-MS Homo sapiens
52 STK11 6794
Negative Genetic Homo sapiens
53 PRC1 9055
Affinity Capture-MS Homo sapiens
54 RCN2 5955
Affinity Capture-MS Homo sapiens
55 ARID1A 8289
Affinity Capture-MS Homo sapiens
56 WHSC1L1  
Affinity Capture-MS Homo sapiens
57 TUFM 7284
Affinity Capture-MS Homo sapiens
58 SMARCD3  
Affinity Capture-MS Homo sapiens
59 CKAP4 10970
Affinity Capture-MS Homo sapiens
60 ATRX 546
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
61 PHF10  
Affinity Capture-MS Homo sapiens
62 SS18L1  
Affinity Capture-MS Homo sapiens
63 SLC25A12 8604
Affinity Capture-MS Homo sapiens
64 BRD3 8019
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
65 RAD51  
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
66 CEBPA  
Proximity Label-MS Homo sapiens
67 BRD4 23476
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
68 SMARCC2 6601
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which BRD9 is involved
No pathways found





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