Gene description for Anp32b
Gene name acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
Gene symbol Anp32b
Other names/aliases 2410015B15Rik
PAL31
PHAPI2a
Ssp29
Species Mus musculus
 Database cross references - Anp32b
ExoCarta ExoCarta_67628
Vesiclepedia VP_67628
Entrez Gene 67628
UniProt Q9EST5  
 Anp32b identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Anp32b
Molecular Function
    histone binding GO:0042393 IBA
    histone binding GO:0042393 IEA
    histone binding GO:0042393 ISO
    RNA polymerase binding GO:0070063 IEA
    RNA polymerase binding GO:0070063 ISO
Biological Process
    G1/S transition of mitotic cell cycle GO:0000082 ISO
    vasculature development GO:0001944 IMP
    nucleosome assembly GO:0006334 IEA
    nucleosome assembly GO:0006334 ISO
    positive regulation of cell population proliferation GO:0008284 ISO
    ventricular system development GO:0021591 IMP
    regulation of apoptotic process GO:0042981 IBA
    negative regulation of apoptotic process GO:0043066 ISO
    negative regulation of cell differentiation GO:0045596 IEA
    negative regulation of cell differentiation GO:0045596 ISO
    positive regulation of protein export from nucleus GO:0046827 IEA
    positive regulation of protein export from nucleus GO:0046827 ISO
    inner ear development GO:0048839 IMP
    roof of mouth development GO:0060021 IMP
    positive regulation of G1/S transition of mitotic cell cycle GO:1900087 ISO
    positive regulation of cysteine-type endopeptidase activity GO:2001056 ISO
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleus GO:0005634 ISO
    nucleoplasm GO:0005654 IEA
    nucleoplasm GO:0005654 ISO
    nucleolus GO:0005730 IEA
    nucleolus GO:0005730 ISO
    cytoplasm GO:0005737 IEA
    cytoplasm GO:0005737 ISO
 Experiment description of studies that identified Anp32b in sEVs
1
Experiment ID 907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Anp32b
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Arpc2 76709
Co-fractionation Mus musculus
2 Actr2 66713
Co-fractionation Mus musculus
3 Actr3 74117
Co-fractionation Mus musculus
4 Eed  
Affinity Capture-MS Mus musculus
5 2510003E04Rik  
Co-fractionation Mus musculus
6 Arpc1b 11867
Co-fractionation Mus musculus
View the network image/svg+xml
 Pathways in which Anp32b is involved
No pathways found





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