Gene description for UPK1B
Gene name
uroplakin 1B
Gene symbol
UPK1B
Other names/aliases
TSPAN20 UPIB UPK1
Species
Homo sapiens
Database cross references - UPK1B
ExoCarta
ExoCarta_7348
Vesiclepedia
VP_7348
Entrez Gene
7348
HGNC
12578
MIM
602380
UniProt
O75841
UPK1B identified in sEVs derived from the following tissue/cell type
Ovarian cancer cells
23333927
Ovarian cancer cells
23333927
Urine
19056867
Gene ontology annotations for UPK1B
Experiment description of studies that identified UPK1B in sEVs
1
Experiment ID
211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
"Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
IGROV1
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
2
Experiment ID
212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
"Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
OVCAR-3
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
3
Experiment ID
63
MISEV standards
✘
Biophysical techniques
✔
AQP2
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
19056867
Organism
Homo sapiens
Experiment description
Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors
"Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name
JASN
Publication year
2009
Sample
Urine
Sample name
Urine - Normal
Isolation/purification methods
Differential centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [LTQ] Western blotting
Protein-protein interactions for UPK1B
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
TMEM91
Two-hybrid
Homo sapiens
2
GJA8
Two-hybrid
Homo sapiens
3
KIR2DL3
Two-hybrid
Homo sapiens
4
GPX8
493869
Two-hybrid
Homo sapiens
5
SYT9
143425
Two-hybrid
Homo sapiens
6
FNDC9
Two-hybrid
Homo sapiens
7
SHISA4
149345
Two-hybrid
Homo sapiens
8
SSMEM1
Two-hybrid
Homo sapiens
9
C6orf57
Two-hybrid
Homo sapiens
10
CD69
Two-hybrid
Homo sapiens
11
FFAR2
Two-hybrid
Homo sapiens
12
SLC16A2
Two-hybrid
Homo sapiens
13
GPR161
Two-hybrid
Homo sapiens
14
MS4A4A
Two-hybrid
Homo sapiens
15
VSIG1
Two-hybrid
Homo sapiens
16
ITGB2
3689
Two-hybrid
Homo sapiens
17
TMEM54
Two-hybrid
Homo sapiens
18
SPINT1
6692
Two-hybrid
Homo sapiens
19
CLDN7
1366
Two-hybrid
Homo sapiens
20
PPAPDC1A
Two-hybrid
Homo sapiens
21
TMUB2
Two-hybrid
Homo sapiens
22
TMEM139
Two-hybrid
Homo sapiens
23
SLC10A2
Two-hybrid
Homo sapiens
24
TMEM194A
Two-hybrid
Homo sapiens
25
FAM209A
200232
Two-hybrid
Homo sapiens
26
CCDC155
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
27
SLC39A2
Two-hybrid
Homo sapiens
28
CD53
963
Two-hybrid
Homo sapiens
29
BCL2L13
23786
Two-hybrid
Homo sapiens
30
STX1A
6804
Two-hybrid
Homo sapiens
31
TMEM262
Two-hybrid
Homo sapiens
32
GJB1
2705
Two-hybrid
Homo sapiens
33
GPR37L1
Two-hybrid
Homo sapiens
34
RHCG
51458
Two-hybrid
Homo sapiens
35
BNIP2
Two-hybrid
Homo sapiens
36
KCNJ6
Two-hybrid
Homo sapiens
37
TMEM45B
120224
Two-hybrid
Homo sapiens
38
PDZK1IP1
10158
Two-hybrid
Homo sapiens
39
SIT1
27240
Two-hybrid
Homo sapiens
40
ISLR2
Two-hybrid
Homo sapiens
41
KLRC1
Two-hybrid
Homo sapiens
42
TMEM237
65062
Two-hybrid
Homo sapiens
43
UPK3A
7380
Affinity Capture-Western
Homo sapiens
44
MFF
56947
Two-hybrid
Homo sapiens
45
DAGLA
747
Two-hybrid
Homo sapiens
46
EDAR
Two-hybrid
Homo sapiens
View the network
image/svg+xml
Pathways in which UPK1B is involved
No pathways found