Gene description for C17orf62
Gene name chromosome 17 open reading frame 62
Gene symbol C17orf62
Other names/aliases -
Species Homo sapiens
 Database cross references - C17orf62
ExoCarta ExoCarta_79415
Vesiclepedia VP_79415
Entrez Gene 79415
HGNC 28672
UniProt Q9BQA9  
 C17orf62 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for C17orf62
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    innate immune response GO:0045087 IMP
    innate immune response GO:0045087 ISS
    respiratory burst after phagocytosis GO:0045728 IMP
    respiratory burst after phagocytosis GO:0045728 ISS
Subcellular Localization
    endoplasmic reticulum GO:0005783 IDA
    endoplasmic reticulum membrane GO:0005789 IEA
 Experiment description of studies that identified C17orf62 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for C17orf62
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GTF2A1 2957
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 CLDN7 1366
Two-hybrid Homo sapiens
3 P2RX4 5025
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 BET1 10282
Two-hybrid Homo sapiens
5 HSD17B11 51170
Two-hybrid Homo sapiens
6 GJA8  
Two-hybrid Homo sapiens
7 LAT 27040
Two-hybrid Homo sapiens
8 NINJ2  
Two-hybrid Homo sapiens
9 MAPRE1 22919
Affinity Capture-MS Homo sapiens
10 GPR151  
Two-hybrid Homo sapiens
11 TRAM1L1  
Two-hybrid Homo sapiens
12 SHISA4 149345
Two-hybrid Homo sapiens
13 PLP1 5354
Two-hybrid Homo sapiens
14 NDUFV3 4731
Affinity Capture-MS Homo sapiens
15 SSMEM1  
Two-hybrid Homo sapiens
16 SPN 6693
Two-hybrid Homo sapiens
17 TMEM80  
Two-hybrid Homo sapiens
18 AIG1  
Two-hybrid Homo sapiens
19 C4orf3  
Two-hybrid Homo sapiens
20 NDUFA9 4704
Affinity Capture-MS Homo sapiens
21 CD79B 974
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 INSIG2  
Two-hybrid Homo sapiens
23 MTIF3  
Two-hybrid Homo sapiens
24 P2RX1 5023
Two-hybrid Homo sapiens
25 GALNT10 55568
Affinity Capture-MS Homo sapiens
26 SYT2  
Affinity Capture-MS Homo sapiens
27 CYBB 1536
Two-hybrid Homo sapiens
28 ERGIC3 51614
Two-hybrid Homo sapiens
29 TMEM128  
Two-hybrid Homo sapiens
30 AGTRAP 57085
Two-hybrid Homo sapiens
31 PEX12  
Two-hybrid Homo sapiens
32 C14orf180  
Two-hybrid Homo sapiens
33 NRM 11270
Two-hybrid Homo sapiens
34 CCDC155  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
35 HSD17B13  
Two-hybrid Homo sapiens
36 AQP3  
Affinity Capture-MS Homo sapiens
37 ETS1  
Reconstituted Complex Homo sapiens
38 JAGN1 84522
Two-hybrid Homo sapiens
39 KIR2DL3  
Two-hybrid Homo sapiens
40 CREB3L1  
Two-hybrid Homo sapiens
41 APCDD1L  
Two-hybrid Homo sapiens
42 DUSP6 1848
Affinity Capture-MS Homo sapiens
43 THBD 7056
Two-hybrid Homo sapiens
44 GPR152  
Two-hybrid Homo sapiens
45 FAM209A 200232
Two-hybrid Homo sapiens
46 TM4SF19  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
47 CD53 963
Two-hybrid Homo sapiens
48 TMPRSS2 7113
Two-hybrid Homo sapiens
49 ADIPOQ 9370
Two-hybrid Homo sapiens
50 APOL2 23780
Two-hybrid Homo sapiens
51 APOA2 336
Two-hybrid Homo sapiens
52 CPLX4  
Two-hybrid Homo sapiens
53 DNAJC11 55735
Affinity Capture-MS Homo sapiens
54 C1orf27 54953
Affinity Capture-MS Homo sapiens
55 PLIN3 10226
Two-hybrid Homo sapiens
56 AQP10  
Two-hybrid Homo sapiens
57 CREB3  
Two-hybrid Homo sapiens
58 PDZK1IP1 10158
Two-hybrid Homo sapiens
59 CISD2 493856
Two-hybrid Homo sapiens
60 UFSP2 55325
Affinity Capture-MS Homo sapiens
61 AHNAK2 113146
Two-hybrid Homo sapiens
62 PLP2 5355
Two-hybrid Homo sapiens
63 CCDC47 57003
Affinity Capture-MS Homo sapiens
64 VANGL1 81839
Affinity Capture-MS Homo sapiens
65 SLC22A4 6583
Affinity Capture-MS Homo sapiens
66 AQP8  
Two-hybrid Homo sapiens
67 TSPAN12  
Two-hybrid Homo sapiens
68 MFF 56947
Two-hybrid Homo sapiens
69 MGST3 4259
Two-hybrid Homo sapiens
70 HIATL1 84641
Two-hybrid Homo sapiens
71 TMX2 51075
Two-hybrid Homo sapiens
72 STX2 2054
Two-hybrid Homo sapiens
73 CLN6  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which C17orf62 is involved
No pathways found





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