Gene description for LAT
Gene name	linker for activation of T cells
Gene symbol	LAT
Other names/aliases	LAT1 pp36
Species	Homo sapiens
Database cross references - LAT
ExoCarta	ExoCarta_27040
Vesiclepedia	VP_27040
Entrez Gene	27040
HGNC	18874
MIM	602354
UniProt	O43561
LAT identified in sEVs derived from the following tissue/cell type
Platelets	25332113
Platelets	25332113
Platelets	25332113
Thymus	23844026

Gene ontology annotations for LAT

Molecular Function     protein binding GO:0005515 IPI     protein kinase binding GO:0019901 IBA     protein kinase binding GO:0019901 IPI     signaling receptor complex adaptor activity GO:0030159 IDA     signaling adaptor activity GO:0035591 IDA     molecular condensate scaffold activity GO:0140693 IDA Biological Process     adaptive immune response GO:0002250 IEA     lymphocyte homeostasis GO:0002260 IEA     inflammatory response GO:0006954 IBA     immune response GO:0006955 IBA     immune response GO:0006955 IDA     integrin-mediated signaling pathway GO:0007229 IDA     Ras protein signal transduction GO:0007265 IMP     gene expression GO:0010467 IEA     calcium-mediated signaling GO:0019722 IMP     membrane raft distribution GO:0031580 IDA     intracellular signal transduction GO:0035556 IBA     intracellular signal transduction GO:0035556 IDA     T cell activation GO:0042110 TAS     mast cell degranulation GO:0043303 IEA     positive regulation of MAPK cascade GO:0043410 IDA     positive regulation of protein kinase activity GO:0045860 IEP     T cell receptor signaling pathway GO:0050852 IDA     regulation of T cell activation GO:0050863 IBA     regulation of T cell activation GO:0050863 IMP Subcellular Localization     immunological synapse GO:0001772 IBA     immunological synapse GO:0001772 IDA     Golgi apparatus GO:0005794 IDA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 TAS     cell-cell junction GO:0005911 IEA     COP9 signalosome GO:0008180 ISS     membrane GO:0016020 IDA     TCR signalosome GO:0036398 IDA     membrane raft GO:0045121 TAS