Gene description for DGKD
Gene name	diacylglycerol kinase, delta 130kDa
Gene symbol	DGKD
Other names/aliases	DGKdelta dgkd-2
Species	Homo sapiens
Database cross references - DGKD
ExoCarta	ExoCarta_8527
Vesiclepedia	VP_8527
Entrez Gene	8527
HGNC	2851
MIM	601826
UniProt	Q16760
DGKD identified in sEVs derived from the following tissue/cell type
Hepatocytes	26054723

Gene ontology annotations for DGKD

Molecular Function     ATP-dependent diacylglycerol kinase activity GO:0004143 IBA     ATP-dependent diacylglycerol kinase activity GO:0004143 IDA     ATP-dependent diacylglycerol kinase activity GO:0004143 TAS     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     kinase binding GO:0019900 IPI     diacylglycerol binding GO:0019992 NAS     identical protein binding GO:0042802 IDA     identical protein binding GO:0042802 IPI     protein homodimerization activity GO:0042803 IDA     metal ion binding GO:0046872 IEA     protein heterodimerization activity GO:0046982 IDA Biological Process     phosphatidic acid biosynthetic process GO:0006654 IBA     phosphatidic acid biosynthetic process GO:0006654 IDA     endocytosis GO:0006897 IEA     signal transduction GO:0007165 TAS     phospholipase C-activating G protein-coupled receptor signaling pathway GO:0007200 IEA     protein transport GO:0015031 IEA     platelet activation GO:0030168 TAS     intracellular signal transduction GO:0035556 IBA     positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 ISS     positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 TAS     diacylglycerol metabolic process GO:0046339 IBA     diacylglycerol metabolic process GO:0046339 IC     diacylglycerol metabolic process GO:0046339 IDA     diacylglycerol catabolic process GO:0046340 IEA     lipid phosphorylation GO:0046834 IDA     negative regulation of phospholipase C/protein kinase C signal transduction GO:0160195 ISS     positive regulation of clathrin-dependent endocytosis GO:2000370 IMP Subcellular Localization     nucleus GO:0005634 TAS     cytoplasm GO:0005737 IDA     cytosol GO:0005829 IDA     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 TAS     clathrin-coated pit GO:0005905 IDA     cytoplasmic vesicle GO:0031410 IDA