Gene description for CD33
Gene name	CD33 molecule
Gene symbol	CD33
Other names/aliases	SIGLEC-3 SIGLEC3 p67
Species	Homo sapiens
Database cross references - CD33
ExoCarta	ExoCarta_945
Vesiclepedia	VP_945
Entrez Gene	945
HGNC	1659
MIM	159590
UniProt	P20138
CD33 identified in sEVs derived from the following tissue/cell type
Neuroblastoma cells	25944692

Gene ontology annotations for CD33

Molecular Function     protein binding GO:0005515 IPI     protein tyrosine phosphatase activator activity GO:0008160 IMP     protein phosphatase binding GO:0019903 IPI     carbohydrate binding GO:0030246 IEA     sialic acid binding GO:0033691 IBA     sialic acid binding GO:0033691 IMP     signaling receptor activity GO:0038023 TAS Biological Process     immune response-inhibiting signal transduction GO:0002765 IDA     cell adhesion GO:0007155 IBA     signal transduction GO:0007165 TAS     cell-cell signaling GO:0007267 TAS     negative regulation of cell population proliferation GO:0008285 TAS     negative regulation of interleukin-1 beta production GO:0032691 IMP     negative regulation of interleukin-8 production GO:0032717 IMP     negative regulation of tumor necrosis factor production GO:0032720 IMP     Fc-gamma receptor signaling pathway GO:0038094 IDA     positive regulation of protein secretion GO:0050714 IMP     cell-cell adhesion GO:0098609 IMP     negative regulation of monocyte activation GO:0150102 IDA Subcellular Localization     nucleoplasm GO:0005654 IDA     peroxisome GO:0005777 IDA     peroxisome GO:0005777 IEA     Golgi apparatus GO:0005794 IDA     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 TAS     external side of plasma membrane GO:0009897 IDA     cell surface GO:0009986 IDA     specific granule membrane GO:0035579 TAS     tertiary granule membrane GO:0070821 TAS