Experiment description of studies that identified SERTAD2 in sEVs

1 Experiment ID 226 MISEV standards ✔ EM Biophysical techniques ✔ GAPDH|CD9|FLOT1 Enriched markers ✔ LMNA|H2AFX|ATP5A1|TOMM20 Negative markers ✘ Particle analysis Identified molecule mRNA Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa) PubMed ID 26027894     Organism Homo sapiens Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting" Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar" Journal name Journal of Extracellular Vesicles Publication year 2015 Sample Endothelial cells Sample name HMEC-1 Isolation/purification methods Differential ultracentrifugation Sucrose density gradient Flotation density 1.10 g/mL Molecules identified in the study miRNA Protein snoRNA lncRNA yRNA snRNA mRNA ncRNA mtRNA vtRNA scaRNA lincRNA Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa) Western blotting

Protein-protein interactions for SERTAD2

Protein Interactor ExoCarta ID Identification method PubMed Species 1 IGFN1   Two-hybrid Homo sapiens 2 CTNNA3   Two-hybrid Homo sapiens 3 PPP2R2B 5521 Affinity Capture-MS Homo sapiens 4 PARVG 64098 Two-hybrid Homo sapiens 5 XPO1 7514 Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens 6 ZNF524   Two-hybrid Homo sapiens 7 KAT2B   Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens 8 ATG12   Two-hybrid Homo sapiens 9 ELAVL1 1994 Affinity Capture-RNA Homo sapiens 10 PPP2R2C 5522 Affinity Capture-MS Homo sapiens 11 SUPT7L   Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens 12 CKS1B   Two-hybrid Homo sapiens 13 PPP2CA 5515 Affinity Capture-MS Homo sapiens 14 HAPLN3 145864 Affinity Capture-MS Homo sapiens 15 PPP2R1B 5519 Affinity Capture-MS Homo sapiens 16 TRIM28 10155 Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens 17 PPP2CB 5516 Affinity Capture-MS Homo sapiens 18 PPP2R1A 5518 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 19 C1orf109   Two-hybrid Homo sapiens 20 KAT5   Two-hybrid Homo sapiens 21 TNS2 23371 Two-hybrid Homo sapiens 22 STRA8   Two-hybrid Homo sapiens 23 ESPNL   Two-hybrid Homo sapiens 24 ZNF581   Two-hybrid Homo sapiens 25 PLA2G6 8398 Two-hybrid Homo sapiens 26 PRKAB2 5565 Two-hybrid Homo sapiens 27 PPP2R2A 5520 Affinity Capture-MS Homo sapiens 28 PPP2R2D 55844 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 29 HELLS 3070 Two-hybrid Homo sapiens 30 ZSCAN22   Two-hybrid Homo sapiens 31 EP300 2033 Affinity Capture-MS Homo sapiens 32 PIK3R3 8503 Two-hybrid Homo sapiens View the network

Pathways in which SERTAD2 is involved

No pathways found