Gene description for HELLS
Gene name	helicase, lymphoid-specific
Gene symbol	HELLS
Other names/aliases	LSH Nbla10143 PASG SMARCA6
Species	Homo sapiens
Database cross references - HELLS
ExoCarta	ExoCarta_3070
Vesiclepedia	VP_3070
Entrez Gene	3070
HGNC	4861
MIM	603946
UniProt	Q9NRZ9
HELLS identified in sEVs derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for HELLS

Molecular Function     chromatin binding GO:0003682 IBA     helicase activity GO:0004386 IEA     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     hydrolase activity GO:0016787 IEA Biological Process     urogenital system development GO:0001655 IEA     kidney development GO:0001822 ISS     DNA methylation-dependent constitutive heterochromatin formation GO:0006346 IBA     DNA methylation-dependent constitutive heterochromatin formation GO:0006346 ISS     apoptotic process GO:0006915 IEA     pericentric heterochromatin formation GO:0031508 IBA     pericentric heterochromatin formation GO:0031508 ISS     negative regulation of gene expression via chromosomal CpG island methylation GO:0044027 IBA     negative regulation of gene expression via chromosomal CpG island methylation GO:0044027 ISS     lymphocyte proliferation GO:0046651 IBA     lymphocyte proliferation GO:0046651 ISS     cell division GO:0051301 IEA     chromosomal DNA methylation maintenance following DNA replication GO:0141119 IEA     cellular response to leukemia inhibitory factor GO:1990830 IEA     negative regulation of intrinsic apoptotic signaling pathway GO:2001243 IEA Subcellular Localization     chromosome, centromeric region GO:0000775 ISS     nucleus GO:0005634 IBA     pericentric heterochromatin GO:0005721 IBA     pericentric heterochromatin GO:0005721 ISS