Gene description for COPA
Gene name coatomer protein complex, subunit alpha
Gene symbol COPA
Other names/aliases -
Species Bos taurus
 Database cross references - COPA
ExoCarta ExoCarta_100126041
Entrez Gene 100126041
UniProt Q27954  
 COPA identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for COPA
Molecular Function
    protein binding GO:0005515 IPI
    structural molecule activity GO:0005198 IEA
    hormone activity GO:0005179 IEA
Biological Process
    intracellular protein transport GO:0006886 IEA
    retrograde vesicle-mediated transport, Golgi to ER GO:0006890 TAS
    pancreatic juice secretion GO:0030157 IEA
    intra-Golgi vesicle-mediated transport GO:0006891 TAS
Subcellular Localization
    extracellular space GO:0005615 IEA
    COPI vesicle coat GO:0030126 IDA
    extracellular exosome GO:0070062 IEA
 Experiment description of studies that identified COPA in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for COPA
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which COPA is involved
PathwayEvidenceSource
COPI Mediated Transport IEA Reactome





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