Gene description for COPA
Gene name coatomer protein complex, subunit alpha
Gene symbol COPA
Other names/aliases -
Species Bos taurus
 Database cross references - COPA
ExoCarta ExoCarta_100126041
Entrez Gene 100126041
UniProt Q27954  
 COPA identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for COPA
Molecular Function
    protein binding GO:0005515 IPI
    structural molecule activity GO:0005198 IEA
    hormone activity GO:0005179 IEA
Biological Process
    intracellular protein transport GO:0006886 IEA
    retrograde vesicle-mediated transport, Golgi to ER GO:0006890 TAS
    pancreatic juice secretion GO:0030157 IEA
    intra-Golgi vesicle-mediated transport GO:0006891 TAS
Subcellular Localization
    extracellular space GO:0005615 IEA
    COPI vesicle coat GO:0030126 IDA
    extracellular exosome GO:0070062 IEA
 Experiment description of studies that identified COPA in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for COPA
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which COPA is involved
PathwayEvidenceSource
COPI Mediated Transport IEA Reactome





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