Gene description for HNRNPCL4
Gene name heterogeneous nuclear ribonucleoprotein C-like 4
Gene symbol HNRNPCL4
Other names/aliases -
Species Homo sapiens
 Database cross references - HNRNPCL4
ExoCarta ExoCarta_101060301
Vesiclepedia VP_101060301
Entrez Gene 101060301
HGNC 51333
UniProt P0DMR1   B7ZW38  
 HNRNPCL4 identified in sEVs derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for HNRNPCL4
Molecular Function
    RNA binding GO:0003723 IBA
Subcellular Localization
    nucleus GO:0005634 IBA
 Experiment description of studies that identified HNRNPCL4 in sEVs
1
Experiment ID 224
MISEV standards
EM|AFM
Biophysical techniques
Alix|TSG101|CD63|CD81
Enriched markers
GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for HNRNPCL4
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GAPDH 2597
Cross-Linking-MS (XL-MS) Homo sapiens
2 AURKB 9212
Affinity Capture-MS Homo sapiens
3 RPL4 6124
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which HNRNPCL4 is involved
No pathways found





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