Gene description for ABCA7
Gene name	ATP-binding cassette, sub-family A (ABC1), member 7
Gene symbol	ABCA7
Other names/aliases	ABCA-SSN ABCX
Species	Homo sapiens
Database cross references - ABCA7
ExoCarta	ExoCarta_10347
Entrez Gene	10347
HGNC	37
MIM	605414
UniProt	Q8IZY2
ABCA7 identified in exosomes derived from the following tissue/cell type
Plasma	19028452

Gene ontology annotations for ABCA7

Molecular Function     apolipoprotein A-I receptor activity GO:0034188 IDA     ATP binding GO:0005524 IEA     ATPase activity, coupled to transmembrane movement of substances GO:0042626 IBA     phospholipid transporter activity GO:0005548 IBA     ATPase activity GO:0016887 IDA     cholesterol transporter activity GO:0017127 IBA     transporter activity GO:0005215 TAS Biological Process     negative regulation of beta-amyloid formation GO:1902430 ISS     cholesterol efflux GO:0033344 IDA     positive regulation of ERK1 and ERK2 cascade GO:0070374 ISS     peptide cross-linking GO:0018149 ISS     positive regulation of beta-amyloid clearance GO:1900223 ISS     positive regulation of cholesterol efflux GO:0010875 ISS     phospholipid scrambling GO:0017121 IDA     apolipoprotein A-I-mediated signaling pathway GO:0038027 IDA     protein localization to nucleus GO:0034504 ISS     memory GO:0007613 ISS     positive regulation of phospholipid efflux GO:1902995 ISS     phagocytosis GO:0006909 IEA     transmembrane transport GO:0055085 TAS     positive regulation of engulfment of apoptotic cell GO:1901076 ISS     high-density lipoprotein particle assembly GO:0034380 IDA     positive regulation of ATPase activity GO:0032781 IDA     phospholipid efflux GO:0033700 IDA     positive regulation of phagocytosis GO:0050766 ISS     negative regulation of amyloid precursor protein biosynthetic process GO:0042985 ISS     negative regulation of ATPase activity GO:0032780 IDA Subcellular Localization     endosome membrane GO:0010008 IEA     Golgi apparatus GO:0005794 IDA     ruffle membrane GO:0032587 ISS     ATP-binding cassette (ABC) transporter complex GO:0043190 TAS     Golgi membrane GO:0000139 IEA     cytoplasm GO:0005737 IDA     plasma membrane GO:0005886 TAS     apical plasma membrane GO:0016324 IEA     integral component of plasma membrane GO:0005887 IBA     cell surface GO:0009986 ISS     integral component of membrane GO:0016021 TAS     phagocytic cup GO:0001891 ISS