Gene description for ATP8A1
Gene name	ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
Gene symbol	ATP8A1
Other names/aliases	ATPASEII ATPIA ATPP2
Species	Homo sapiens
Database cross references - ATP8A1
ExoCarta	ExoCarta_10396
Vesiclepedia	VP_10396
Entrez Gene	10396
HGNC	13531
MIM	609542
UniProt	Q9Y2Q0
ATP8A1 identified in sEVs derived from the following tissue/cell type
Platelets	25332113
Platelets	25332113
Platelets	25332113

Gene ontology annotations for ATP8A1

Molecular Function     magnesium ion binding GO:0000287 IEA     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     ATP hydrolysis activity GO:0016887 IEA     ATPase-coupled monoatomic cation transmembrane transporter activity GO:0019829 NAS     phosphatidylserine floppase activity GO:0090556 IEA     ATPase-coupled intramembrane lipid transporter activity GO:0140326 IBA     ATPase-coupled intramembrane lipid transporter activity GO:0140326 TAS     phosphatidylserine flippase activity GO:0140346 IDA     phosphatidylserine flippase activity GO:0140346 ISS Biological Process     learning GO:0007612 IEA     positive regulation of cell migration GO:0030335 IEA     monoatomic ion transmembrane transport GO:0034220 TAS     phospholipid translocation GO:0045332 IBA     phospholipid translocation GO:0045332 NAS     synaptic vesicle endocytosis GO:0048488 IEA     positive regulation of phospholipid translocation GO:0061092 IEA     monoatomic cation transmembrane transport GO:0098655 IEA     aminophospholipid translocation GO:0140331 IDA     aminophospholipid translocation GO:0140331 ISS     transport across blood-brain barrier GO:0150104 NAS Subcellular Localization     endoplasmic reticulum GO:0005783 IDA     Golgi apparatus GO:0005794 IDA     trans-Golgi network GO:0005802 IBA     cytosol GO:0005829 IDA     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 TAS     membrane GO:0016020 HDA     synaptic vesicle membrane GO:0030672 IEA     organelle membrane GO:0031090 ISS     cytoplasmic vesicle GO:0031410 ISS     azurophil granule membrane GO:0035577 TAS     specific granule membrane GO:0035579 TAS     chromaffin granule membrane GO:0042584 IEA     intracellular membrane-bounded organelle GO:0043231 IDA     extracellular exosome GO:0070062 HDA     glutamatergic synapse GO:0098978 IEA     phospholipid-translocating ATPase complex GO:1990531 IDA     phospholipid-translocating ATPase complex GO:1990531 IPI