Gene description for Aldh1l1
Gene name aldehyde dehydrogenase 1 family, member L1
Gene symbol Aldh1l1
Other names/aliases 1810048F20Rik
Species Mus musculus
 Database cross references - Aldh1l1
ExoCarta ExoCarta_107747
Entrez Gene 107747
UniProt Q8R0Y6  
 Aldh1l1 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Aldh1l1
Molecular Function
    hydroxymethyl-, formyl- and related transferase activity GO:0016742 IEA
    protein complex binding GO:0032403 ISO
    oxidoreductase activity GO:0016491 IEA
    aldehyde dehydrogenase (NADP+) activity GO:0033721 ISO
    catalytic activity GO:0003824 IEA
    formyltetrahydrofolate dehydrogenase activity GO:0016155 IBA
    oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 IEA
    aldehyde dehydrogenase [NAD(P)+] activity GO:0004030 ISO
    aldehyde dehydrogenase (NAD) activity GO:0004029 IBA
    protein binding GO:0005515 IPI
    methyltransferase activity GO:0008168 IEA
Biological Process
    10-formyltetrahydrofolate catabolic process GO:0009258 IEA
    oxidation-reduction process GO:0055114 IBA
    metabolic process GO:0008152 IEA
    biosynthetic process GO:0009058 IEA
    one-carbon metabolic process GO:0006730 IEA
Subcellular Localization
    mitochondrion GO:0005739 IDA
    extracellular exosome GO:0070062 ISO
    protein complex GO:0043234 ISO
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified Aldh1l1 in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Aldh1l1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Aldh1l1 is involved
No pathways found

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