Gene description for Prkag2
Gene name protein kinase, AMP-activated, gamma 2 non-catalytic subunit
Gene symbol Prkag2
Other names/aliases 2410051C13Rik
AAKG
AAKG2
AI854673
H91620p
WPWS
Species Mus musculus
 Database cross references - Prkag2
ExoCarta ExoCarta_108099
Entrez Gene 108099
UniProt Q91WG5  
 Prkag2 identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Prkag2
Molecular Function
    protein kinase activator activity GO:0030295 ISO
    protein kinase binding GO:0019901 ISO
    AMP binding GO:0016208 ISO
    ADP binding GO:0043531 ISO
    cAMP-dependent protein kinase inhibitor activity GO:0004862 ISO
    nucleotide binding GO:0000166 IEA
    AMP-activated protein kinase activity GO:0004679 TAS
    ATP binding GO:0005524 ISO
    phosphorylase kinase regulator activity GO:0008607 ISO
    cAMP-dependent protein kinase regulator activity GO:0008603 ISO
Biological Process
    regulation of catalytic activity GO:0050790 ISO
    protein phosphorylation GO:0006468 TAS
    fatty acid biosynthetic process GO:0006633 IEA
    lipid metabolic process GO:0006629 IEA
    negative regulation of protein serine/threonine kinase activity GO:0071901 ISO
    intracellular signal transduction GO:0035556 ISO
    positive regulation of protein kinase activity GO:0045860 ISO
    fatty acid metabolic process GO:0006631 IEA
    negative regulation of protein kinase activity GO:0006469 ISO
    glycogen metabolic process GO:0005977 ISO
    regulation of fatty acid metabolic process GO:0019217 ISO
    regulation of glycolytic process GO:0006110 ISO
    positive regulation of peptidyl-threonine phosphorylation GO:0010800 ISO
Subcellular Localization
    AMP-activated protein kinase complex GO:0031588 ISO
    extracellular space GO:0005615 ISO
 Experiment description of studies that identified Prkag2 in exosomes
1
Experiment ID 188
ISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Prkag2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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