Gene description for CFHR3
Gene name complement factor H-related 3
Gene symbol CFHR3
Other names/aliases CFHL3
DOWN16
FHR-3
FHR3
HLF4
Species Homo sapiens
 Database cross references - CFHR3
ExoCarta ExoCarta_10878
Entrez Gene 10878
HGNC 16980
MIM 605336
UniProt Q02985  
 CFHR3 identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for CFHR3
Subcellular Localization
    extracellular space GO:0005615 TAS
    extracellular exosome GO:0070062 IDA
    blood microparticle GO:0072562 IDA
 Experiment description of studies that identified CFHR3 in exosomes
1
Experiment ID 63
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✔
AQP2
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for CFHR3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 C3 718
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which CFHR3 is involved
PathwayEvidenceSource
Regulation of Complement cascade TAS Reactome





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